Tag: M.W=600-700

These common heterocyclic compound, 61326-44-1, name is 1,1,2,2-Tetrakis(4-bromophenyl)ethene, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. Safety of 1,1,2,2-Tetrakis(4-bromophenyl)ethene

Mixture of 1 (3 g, 4.63 mmol), potassium acetate (4.56 g, 46.50 mmol), bis(pinacolato)diboron(5.30 g, 20.4 mmol), and anhydrous dioxane (90 mL) was put into a three-neckedflask and argon gas was bubbled for 30 min. [1,10-Bis(diphenylphosphino)ferrocene]dichloropalladium (II) in dichloromethane (180 mg, 0.22 mmol) were added to the flaskunder argon. The mixture was charged with argon gas for 30 min and then stirred at110 C for 3 days. After cooling to room temperature, the reaction mixture was pouredinto cold water. The precipitate was isolated by filtration and dried in a vacuum oven.The residue was dissolved in chloroform and purified by column chromatography (eluent:chloroform: ethyl acetate 1:1). The resulting white solid was washed with methanol anddried (yield 3.16 g, 82%). 1H NMR (300MHz, CDCl3) 7.5 (8H, d), 7.0 (8H, d) ppm, 1.3(24H, s) ppm. FT-IR (KBr pellet, cm1): 2981 (C-H), 1606 (CC), 1359 (B-O).

The synthetic route of 1,1,2,2-Tetrakis(4-bromophenyl)ethene has been constantly updated, and we look forward to future research findings.

Reference:
Article; Lee, Jeong Jun; Lee, Taek Seung; Molecular Crystals and Liquid Crystals; vol. 686; 1; (2019); p. 1 – 8;,
Bromide – Wikipedia,
bromide – Wiktionary

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 61326-44-1, name is 1,1,2,2-Tetrakis(4-bromophenyl)ethene belongs to bromides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. Product Details of 61326-44-1

[0070] Synthesis of tcbpe-F (Ri = F, R2 to R4 = H in Scheme 1): To a 250m1 three-neck flask, tetra-(4-bromo-phenyl)ethylene (tpe-Br, 2.71 g, 4.2 mmol), 3-fluoro-4- (methoxycarbonyl)phenylboronic acid (5.OOg, 25.2 mmol) and Pd(PPh3)4 (0.40g ) were added, then THF (100 mL) and K2C03 aqueous solution (3.OM, 15 mL) were added under nitrogen protection at room temperature. The mixture solution was kept at 90 °C for three days. After cooling to room temperature, the reaction solution was extracted with dichloromethane for three times (100 mL x 3). The organic phase was washed with water, dried with anhydrous magnesium sulfate. The crude mixture was purified by flash chromatography using dichloromethane/methanol (V : V =40: 1) as fluent. The product, tcbpe-F-ester, was obtained as green-yellow solid in 63.3percent yield (2.50 g). ?H NMR (400 MHz, CDC13) t5: 7.90 (t, J= 10.8 Hz), 7.36 (d, 8H,J= 11.2 Hz), 7.28 (m, 8H), 7.12(d, 8H,J= 11.2 Hz), 3.87(s, 12H).

The synthetic route of 61326-44-1 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY; LI, Jing; HU, Zhichao; GONG, Qihan; WO2015/164784; (2015); A1;,
Bromide – Wikipedia,
bromide – Wiktionary

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 61326-44-1, name is 1,1,2,2-Tetrakis(4-bromophenyl)ethene, A new synthetic method of this compound is introduced below., Computed Properties of C26H16Br4

General procedure: A mixture of 1-(4-bromophenyl)-1,2,2-triphenylethylene (1) (200 mg, 0.48 mmol) and 4-(2,2-diphenylvinyl)phenylboronic acid (8) (174 mg, 0.58 mmol) were dissolved in toluene (10 mL) under argon atmosphere. Aqueous solution of K2CO3 (2 ml, 2 M), tricaprylylmethyl ammoniumchloride (Aliquat® 336) (3 drops) and Pd(PPh)4 (10 mg) was added to the mixture. The reaction mixture was heated at 90 ºC overnight. After being cooled to room temperature, distilled water (5 mL) was added and extracted with dichloromethane (3×10 mL). Organic layer was dried over anhydrous Na2SO4. The solvent was removed under reduced pressure, the residue was purified using column chromatography (silica gel/ethyl acetate: petroleum ether 5:95) affoarded the compound 10 (240 mg, 85percent) as a white solid.

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.

Reference:
Article; Jana, Debabrata; Ghorai, Binay K.; Tetrahedron Letters; vol. 53; 50; (2012); p. 6838 – 6842;,
Bromide – Wikipedia,
bromide – Wiktionary

Related Products of 61326-44-1, The chemical industry reduces the impact on the environment during synthesis 61326-44-1, name is 1,1,2,2-Tetrakis(4-bromophenyl)ethene, I believe this compound will play a more active role in future production and life.

Using the polar solvent “one-pot synthesis”, the 1, 1, 2, 2-tetra (4-bromophenyl) ethylene, 1H-1, 2, 4-triazole, potassium carbonate, and copper oxide in the preparation of the heating condition; wherein the 1, 1, 2, 2-tetra (4-bromophenyl) ethylene: 1H-1, 2, 4-triazole: potassium carbonate: copper oxide in a molar ratio of 2:10-15 : 30:1; the reaction temperature 80-200°C, reaction time 12-120 hours. The present invention is preferably 1, 1, 2, 2-tetra (4-bromophenyl) ethylene: 1H-1, 2, 4-triazole: potassium carbonate: copper oxide in a molar ratio of 2:10-15 : 30:1; the reaction temperature is 100 °C, the reaction time is 48 hours. In the polar solvent, the “one-pot synthesis”, the 1, 1, 2, 2-tetra (4-bromophenyl) ethylene, 1H-1, 2, 4-triazole, potassium carbonate, and copper oxide under the heating condition preparing 1, 1, 2, 2-tetra [4 – (1H-1, 2, 4-triazole-1-yl) phenyl] ethylene (L). Yield 60percent

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1,1,2,2-Tetrakis(4-bromophenyl)ethene, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; Tianjin Normal University; Wang, yin; (12 pag.)CN105418655; (2016); A;,
Bromide – Wikipedia,
bromide – Wiktionary

Adding a certain compound to certain chemical reactions, such as: 61326-44-1, name is 1,1,2,2-Tetrakis(4-bromophenyl)ethene, belongs to bromides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 61326-44-1, Product Details of 61326-44-1

Under argon protection,Tetrakis(4-bromophenyl)ethene 210.7 mg, 0.33 mmol) was added to the reaction flask in that order.3,4,5-trifluorobenzeneboronic acid (274.9 mg, 1.56 mmol),Potassium carbonate (135.4 mg, 0.98 mmol),Tetrakis(triphenylphosphine)palladium (20.3 mg, 0.018 mmol),Tetrabutylammonium bromide (12.3 mg, 0.038 mmol),Add 20 mL of toluene and 5 mL of deionized water.The mixture was heated to 100 ° C, reacted for 27 h, and the reaction was monitored by thin layer chromatography.After the system was lowered to 27 ° C, the liquid was separated.The aqueous phase was extracted with dichloromethane (15 mL×3) and the organic phases were combined.Add anhydrous sodium sulfate and filter,The filtrate is concentrated and subjected to thin layer chromatography.The developing agent ratio is dichloromethane: n-hexane (V: V) = 2:1,The bright blue band of the product (observed under a 365 nm UV lamp) is scraped off.After fully crushing, pour into a sand core funnel and rinse with 80 mL of dichloromethane.Evaporate dry solvent,Obtaining a yellow solid is the target product F-TPE,The weight was 169.2 mg, and the yield was 61.02percent.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1,1,2,2-Tetrakis(4-bromophenyl)ethene, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; University of Jinan; Miao Jinling; Xiong Zhixin; Nie Yong; Zhang Hao; (15 pag.)CN108947766; (2018); A;,
Bromide – Wikipedia,
bromide – Wiktionary

Reference of 61326-44-1,Some common heterocyclic compound, 61326-44-1, name is 1,1,2,2-Tetrakis(4-bromophenyl)ethene, molecular formula is C26H16Br4, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

The present invention is preferably 1,1,2,2-tetrakis(4-bromophenyl)ethylene: 1H-1,2,4-triazole: potassium carbonate: copper oxide molar ratio of 2: 10-15: 30: 1; Reaction temperature of 100 deg.C. The reaction time was 48 hours. In a polar solvent, using the “one-pot method”, 1,1,2,2-tetrakis(4-bromophenyl)ethylene,1H-1,2,4-triazole, potassium carbonate and copper oxide under heating conditions 1,1,2,2-tetrakis[4-(1H-1,2,4-triazol-1-yl)phenyl]ethylene (L) is prepared. Yield 60percent.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 1,1,2,2-Tetrakis(4-bromophenyl)ethene, its application will become more common.

Reference:
Patent; Tianjin Normal University; Wang, Ying; (12 pag.)CN105669705; (2016); A;,
Bromide – Wikipedia,
bromide – Wiktionary

Related Products of 61326-44-1, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 61326-44-1, name is 1,1,2,2-Tetrakis(4-bromophenyl)ethene belongs to bromides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.

(1) A mixture of 3,4,2 mg of palladium acetate, 200 g of K2CO3 and 44 mg of tricyclohexylphosphine was added to the reaction tube under N2, followed by addition of 10 mL of DMF and 130 g of 4-vinylpyridine, followed by heating under reflux for 48 h Room temperature. The solvent was removed by rotary evaporator, the product was extracted with CHCl3, washed with water, the organic phase was collected, and dried over anhydrous Mg2SO4. The final organic phase was purified by silica gel column chromatography eluting with CHCl3: MeOH = 30: 1 to give the final product 6.

The synthetic route of 1,1,2,2-Tetrakis(4-bromophenyl)ethene has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Northwest University; Cao Liping; Li Yawen; Dong Yunhong; (17 pag.)CN107141250; (2017); A;,
Bromide – Wikipedia,
bromide – Wiktionary

Synthetic Route of 61326-44-1, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 61326-44-1, name is 1,1,2,2-Tetrakis(4-bromophenyl)ethene belongs to bromides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.

Preparation of 1- (4- (4- (1H-1,2,4-triazol-1-yl) phenoxy) phenyl) -1H-1,2,4-triazole (L) _: The organic compound is prepared by heating 1,1,2,2-tetrakis (4-bromophenyl) ethylene, triazole, potassium carbonate and copper oxide under heating in a DMF polar solvent;The molar ratio of 4,4′-dibromodiphenyl ether: triazole: potassium carbonate: copper oxide is 2: 10: 30: 1;The reaction temperature was 150 ° C and the reaction time was 18 hours.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1,1,2,2-Tetrakis(4-bromophenyl)ethene, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; Tianjin Normal University; Wang, Ying; (11 pag.)CN104530092; (2017); B;,
Bromide – Wikipedia,
bromide – Wiktionary

Electric Literature of 105309-59-9, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 105309-59-9 name is Tetrakis(4-bromophenyl)methane, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.

Cz (2.5 g, 8.9 mmol), intermediate TBrBen (2.8 g, 4.5 mmol), CuI (0.19 g, 1.0 mmol) and K3PO4 (1.69 g, 8.0 mmol) were added to 100 mL of toluene.The reaction was carried out under argon gas protection and reflux for 24 hours.After removing the solvent, the residue was extracted with dichloromethane (3×100 mL).The organic phases were combined and dried over anhydrous magnesium sulfate.The residue obtained by concentration was purified by column chromatography using dichloromethane: n-hexane (7:3) as eluent to afford product DCzCBr (2.7 g, yield 50.3%).Identification of intermediates by mass spectrometry,The result is:

At the same time, in my other blogs, there are other synthetic methods of this type of compound, Tetrakis(4-bromophenyl)methane, and friends who are interested can also refer to it.

Reference:
Patent; Yangtze Normal University; Yang Yezi; Yao Chuang; Sun Changqing; (13 pag.)CN108752320; (2018); A;,
Bromide – Wikipedia,
bromide – Wiktionary

Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 105309-59-9, name is Tetrakis(4-bromophenyl)methane, A new synthetic method of this compound is introduced below., Application In Synthesis of Tetrakis(4-bromophenyl)methane

(a) Add tetra-[4-bromo-phenyl]methane 0.636 g (1 mmoL) and tetrakistriphenylphosphine palladium 0.18 g to a 50 mL two-necked round bottom flask and add toluene/tetrahydrofuran mixed solvent 20 mL under a vacuum of nitrogen. (volume ratio is 1:1), stir and dissolve uniformly, then inject 3-butylthiophene tributyl group 3.642g (8mmoL), raise the temperature to 140C, and react for 24 hours under light-proof conditions. After the reaction was completed, the mixture was extracted with methylene chloride, and the extract was spin-dried and separated by a column. Silica gel was used as a filler, and petroleum ether and methylene chloride (4:1 by volume) were used as eluent to give a pale yellow product (0.39 g). The yield is 40%.

The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.

Reference:
Patent; Zhejiang University of Technology; Zhang Cheng; Dai Yuyu; Li Weijun; Yan Shuanma; Qu Xingxing; Chen Lan; (11 pag.)CN107188902; (2017); A;,
Bromide – Wikipedia,
bromide – Wiktionary