Tag: M.W=600-700

Application of 61326-44-1,Some common heterocyclic compound, 61326-44-1, name is 1,1,2,2-Tetrakis(4-bromophenyl)ethene, molecular formula is C26H16Br4, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

The present invention is preferably 1,1,2,2-tetrakis(4-bromophenyl)ethylene: 1H-1,2,4-triazole: potassium carbonate: copper oxide molar ratio of 2: 10-15: 30: 1; Reaction temperature of 100 deg.C. The reaction time was 48 hours. In a polar solvent, using the “one-pot method”, 1,1,2,2-tetrakis(4-bromophenyl)ethylene,1H-1,2,4-triazole, potassium carbonate and copper oxide under heating conditions 1,1,2,2-tetrakis[4-(1H-1,2,4-triazol-1-yl)phenyl]ethylene (L) is prepared. Yield 60percent.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 1,1,2,2-Tetrakis(4-bromophenyl)ethene, its application will become more common.

Reference:
Patent; Tianjin Normal University; Wang, Ying; (12 pag.)CN105669705; (2016); A;,
Bromide – Wikipedia,
bromide – Wiktionary

Reference of 61326-44-1, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 61326-44-1, name is 1,1,2,2-Tetrakis(4-bromophenyl)ethene belongs to bromides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.

(1) A mixture of 3,4,2 mg of palladium acetate, 200 g of K2CO3 and 44 mg of tricyclohexylphosphine was added to the reaction tube under N2, followed by addition of 10 mL of DMF and 130 g of 4-vinylpyridine, followed by heating under reflux for 48 h Room temperature. The solvent was removed by rotary evaporator, the product was extracted with CHCl3, washed with water, the organic phase was collected, and dried over anhydrous Mg2SO4. The final organic phase was purified by silica gel column chromatography eluting with CHCl3: MeOH = 30: 1 to give the final product 6.

The synthetic route of 1,1,2,2-Tetrakis(4-bromophenyl)ethene has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Northwest University; Cao Liping; Li Yawen; Dong Yunhong; (17 pag.)CN107141250; (2017); A;,
Bromide – Wikipedia,
bromide – Wiktionary

Synthetic Route of 105309-59-9, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 105309-59-9 name is Tetrakis(4-bromophenyl)methane, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.

Cz (2.5 g, 8.9 mmol), intermediate TBrBen (2.8 g, 4.5 mmol), CuI (0.19 g, 1.0 mmol) and K3PO4 (1.69 g, 8.0 mmol) were added to 100 mL of toluene.The reaction was carried out under argon gas protection and reflux for 24 hours.After removing the solvent, the residue was extracted with dichloromethane (3×100 mL).The organic phases were combined and dried over anhydrous magnesium sulfate.The residue obtained by concentration was purified by column chromatography using dichloromethane: n-hexane (7:3) as eluent to afford product DCzCBr (2.7 g, yield 50.3%).Identification of intermediates by mass spectrometry,The result is:

At the same time, in my other blogs, there are other synthetic methods of this type of compound, Tetrakis(4-bromophenyl)methane, and friends who are interested can also refer to it.

Reference:
Patent; Yangtze Normal University; Yang Yezi; Yao Chuang; Sun Changqing; (13 pag.)CN108752320; (2018); A;,
Bromide – Wikipedia,
bromide – Wiktionary

Application of 61326-44-1, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 61326-44-1, name is 1,1,2,2-Tetrakis(4-bromophenyl)ethene belongs to bromides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.

Step 2, under nitrogen protection, in a 100 mL three-necked flask was added 0.60 g of compound A, 0.72 g of 4-methoxybenzeneboronic acid, 0.60g TauBetaAlphaBeta,3.6 mL of a 2 mol aqueous solution of potassium carbonate, 0.60 g of tetrakistriphenylphosphine palladium and 25 mL of toluene, stirred at 80 ° C for 16 h, extracted with CH2CI2 (40 mL X 3 ) Rotary steaming, column chromatography:PE: EA = 50:1 gave compound B.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1,1,2,2-Tetrakis(4-bromophenyl)ethene, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; Changzhou University; Xiao Tangxin; Zhou Ling; Li Zhengyi; Sun Xiaoqiang; (7 pag.)CN109879858; (2019); A;,
Bromide – Wikipedia,
bromide – Wiktionary

In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 61326-44-1 as follows. Recommanded Product: 1,1,2,2-Tetrakis(4-bromophenyl)ethene

A mixture of tetrakis(4-bromophenyl)ethene(0.65 g, 1.0 mmol), bis(pinacolato)diboron (1.50 g, 6.0 mmol), 1,10 -bis(diphenylphosphino)ferrocene-palladium(II)dichloride dichloromethanecomplex (Pd(dppf)Cl2CH2Cl2) (0.041 g, 0.05 mmol), and potassiumacetate (KOAc) (1.60 g, 16.0 mmol) in 30 mL degassed 1,2-dimethoxyethane (DME) was heated to 100 C for 12 h under N2. Aftercooling down, the solvent was removed in vacuum, and the residue wassubjected to chromatography on a silica gel column using chloroform aseluent. Repeated column chromatography and the following recrystallizationfrom chloroform and methanol afforded the target white compoundTMDB-TPE (0.63 g, yield 75.0%). 1H NMR (400 MHz, CDCl3-d):7.50 (d, 8H, J 8.00 Hz), 6.99 (d, 8H, J 8.00 Hz), 1.32 (s, 48H).MALDI-TOF MS: an isotopic cluster peaking at m/z 836.4, Calcd. forC50H64B4O8, [M] 836.5. Anal. Calcd. for C50H64B4O80.4CHCl3: C,68.47; H, 7.34. Found: C, 68.43; H, 7.18.

According to the analysis of related databases, 61326-44-1, the application of this compound in the production field has become more and more popular.

Reference:
Article; Zheng, Yingting; Wang, Hailong; Jiang, Jianzhuang; Dyes and Pigments; vol. 173; (2020);,
Bromide – Wikipedia,
bromide – Wiktionary

Related Products of 61326-44-1, These common heterocyclic compound, 61326-44-1, name is 1,1,2,2-Tetrakis(4-bromophenyl)ethene, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

TPE-4Br (130 mg, 0.2 mmol), Py-4BO (440 mg, 1.0 mmol), Pd(PPh3)4 (0.10 g, 0.08 mmol) andpotassium carbonate (553 mg, 4.0 mmol) in toluene (20 mL) and distilled water (7 mL) wereadded into a 200 mL Schlenk tube. The resultant mixture was refluxed for 3 days under argon,then extracted with dichloromethane. The combined organic extracts were dried overanhydrous Na2SO4 and concentrated by rotary evaporation. The crude product was purified bycolumn chromatography on silica gel using chloroform/petroleum ether (v/v=1/5) as eluent. Alight yellow solid was finally produced in the yield of 30percent (95 mg). 1H NMR (300 MHz, CDCl3,delta): 8.27 (s, 4H), 8.19 (s, 8H), 8.13 (s, 4H), 8.06 (s, 4H), 8.04 (s, 8H), 7.62 (t, 16H), 1.28 (s, 72H). 13CNMR (75Hz, CDCl3, delta): 148.7, 148.2, 143.1, 140.6, 139.5, 139.3, 131.7, 130.9, 130.7, 130.4, 129.9,129.5, 127.7, 127.6, 127.1, 123.1, 122.3, 122.0, 121.8, 121.0, 35.1, 31.9, 31.6, 29.6. MS (MALDI TOF),m/z: 1580.9053 ([M+], calcd for C112H116, 1580.9077). Anal. Calcd for C112H116: C, 92.61; H, 7.39.Found: C, 92.23; H, 7.47.

Statistics shows that 1,1,2,2-Tetrakis(4-bromophenyl)ethene is playing an increasingly important role. we look forward to future research findings about 61326-44-1.

Reference:
Article; Yang, Jie; Qin, Jianwen; Ren, Zichun; Peng, Qian; Xie, Guohua; Li, Zhen; Molecules; vol. 22; 12; (2017);,
Bromide – Wikipedia,
bromide – Wiktionary

Synthetic Route of 61326-44-1, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 61326-44-1 name is 1,1,2,2-Tetrakis(4-bromophenyl)ethene, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.

General procedure: Chlorodimethyl(octyl)silane (1.03 g, 5.0mmol) was used as reagentinstead of chlorotrimethylsilane. The reaction and purification wereconducted by following the same procedure as that for the synthesisof TPE1. The final product was obtained as a slightly colorless liquid.1H NMR (500 MHz, CDCl3, delta): 7.19 (d, 8H), 6.96 (d, 8H), 1.25?0.66 (m,68H), 0.18 (s, 24H).

At the same time, in my other blogs, there are other synthetic methods of this type of compound, 1,1,2,2-Tetrakis(4-bromophenyl)ethene, and friends who are interested can also refer to it.

Reference:
Article; Jin, Young-Jae; Choi, Young-Ghil; Park, Hyosang; Kwak, Giseop; Journal of Molecular Liquids; vol. 265; (2018); p. 260 – 268;,
Bromide – Wikipedia,
bromide – Wiktionary

Reference of 61326-44-1, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 61326-44-1 name is 1,1,2,2-Tetrakis(4-bromophenyl)ethene, This compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.

In a polar solvent, 1,1,2,2-tetrakis (4-bromophenyl) ethylene, 1,1,2,2-tetrakis (4-bromophenyl)1H-1,2,4-triazole,Potassium carbonate andCopper oxide in the reaction conditions;Wherein 1,1,2,2-tetrakis (4-bromophenyl) ethylene:1H-1,2,4-triazole:Potassium carbonate:The molar ratio of copper oxide is 2: 10-15: 30: 1;The reaction temperature is 80-200 DEG C, the reaction time is 12-120 hoursThe present invention is preferably 1,1,2,2-tetrakis (4-bromophenyl) ethylene:1H-1,2,4-triazole:Potassium carbonate:The molar ratio of copper oxide was2: 10-15: 30: 1;Reaction temperature 100 ,The reaction time was 48 hours.In a polar solvent,Using the “one-pot method”1, 1, 2,(4-bromophenyl) ethene, 1H-1,2,4-triazole, potassium carbonate and copper oxide were heated under heating to produce 1,1,2,2-tetrakis [4-(1H-1,2,4-triazol-1-yl) phenyl] ethylene (L). Yield 60percent.

At the same time, in my other blogs, there are other synthetic methods of this type of compound, 1,1,2,2-Tetrakis(4-bromophenyl)ethene, and friends who are interested can also refer to it.

Reference:
Patent; Tianjin Normal University; Wang, Ying; (11 pag.)CN105524086; (2016); A;,
Bromide – Wikipedia,
bromide – Wiktionary

Reference of 61326-44-1, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 61326-44-1, name is 1,1,2,2-Tetrakis(4-bromophenyl)ethene belongs to bromides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.

the intermediate 14 (1.30g, 2mmol), intermediate 5 (4.44g, 12mmol), four (triphenylphosphine) palladium (280 mg, 0 . 24mmol) and sodium carbonate (1.06g, 10mmol) added to the reaction in the bottle, the substitute gas three times, under the protection of nitrogen injection THF (80 ml) and H2 O (20 ml), 80 °C heating reflux reaction 24h. Water quenching reaction, by methylene chloride extraction, after concentrating makes the powder, eluent for (petroleum ether/dichloromethane=10/1) column, to obtain the final product TPE – TB, yield 85percent.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1,1,2,2-Tetrakis(4-bromophenyl)ethene, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; South China University of Technology; Tang Benzhong; Chen Long; Zhao Zujin; Qin Anjun; Hu Rongrong; (18 pag.)CN104031077; (2017); B;,
Bromide – Wikipedia,
bromide – Wiktionary

Synthetic Route of 61326-44-1, A common heterocyclic compound, 61326-44-1, name is 1,1,2,2-Tetrakis(4-bromophenyl)ethene, molecular formula is C26H16Br4, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

Under the protection of high purity nitrogen,In the 50ml schleckThe reaction flask was charged with 15 ml of tetrakis (4-bromophenyl) ethane (648 mg, 1 Ommol, 1. eqq), Pd (PPh3) 4 (116 mg, 0 lmmol, 0 leq) and re-distilled toluene After dissolving, 3 ml of an ethanol solution dissolved in 4-methoxyphenylphenylborate borane (1170 mg, 5 O Ommol, 5 Oeq) and 1 ml of an aqueous solution of 2MNa2C03 were added to the reaction flask by means of a syringe, and the reaction solution was heated to 50 to 70 C was refluxed for 12 h, cooled to room temperature, extracted with dichloromethane / water. The combined organic layers were dried over anhydrous sodium sulfate. The solvent was removed under reduced pressure and recrystallized from ethanol to give 545 mg of a white solid in 72percent yield.

The synthetic route of 61326-44-1 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; TECHNICAL INSTITUTE OF PHYSICS AND CHEMISTRY, CHINESE ACADEMY OF SCIENCES; LI YI, LI YI; HAO, QINGSHAN; CHEN, JINPING; ZENG, YI; YU, TIANJUN; (14 pag.)CN104557552; (2016); B;,
Bromide – Wikipedia,
bromide – Wiktionary