Tag: M.W=400-500

SDS of cas: 119707-74-3. The protonation of heteroatoms in aromatic heterocycles can be divided into two categories: lone pairs of electrons are in the aromatic ring conjugated system; and lone pairs of electrons do not participate. Compound: (S)-3,3′-Dibromo-1,1′-bi-2-naphthol, is researched, Molecular C20H12Br2O2, CAS is 119707-74-3, about Asymmetric allylboration of ketones catalyzed by chiral diols. Author is Lou, Sha; Moquist, Philip N.; Schaus, Scott E..

Chiral BINOL-derived diols catalyzed the asym. allylboration of ketones. The reaction required 3,3′-Br2-BINOL as the catalyst and allyldiisopropoxyborane as the nucleophile. The reaction products were obtained in good yields and high enantiomeric ratios. High diastereoselectivities and enantioselectivities were obtained in the reactions of acetophenone with crotyldiisopropoxyboranes.

Compound(119707-74-3)SDS of cas: 119707-74-3 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound((S)-3,3′-Dibromo-1,1′-bi-2-naphthol), if you are interested, you can check out my other related articles.

Reference:
Bromide – Wikipedia,
bromide – Wiktionary

Muncipinto, Giovanni; Moquist, Philip N.; Schreiber, Stuart L.; Schaus, Scott E. published an article about the compound: (S)-3,3′-Dibromo-1,1′-bi-2-naphthol( cas:119707-74-3,SMILESS:OC1=C(Br)C=C2C=CC=CC2=C1C3=C4C=CC=CC4=CC(Br)=C3O ).COA of Formula: C20H12Br2O2. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:119707-74-3) through the article.

The first diastereoselective Petasis reaction catalyzed by chiral biphenols that enables the synthesis of syn and anti β-amino alcs. in pure form has been developed. The reaction exploits a multicomponent approach that involves boronates, α-hydroxy aldehydes, and amines: R1CH(OH)CHO + R2R3NH + R4B(OEt)2 → R1CH(OH)CH(NR2R3)R4.

Compound(119707-74-3)COA of Formula: C20H12Br2O2 received a lot of attention, and I have introduced some compounds in other articles, similar to this compound((S)-3,3′-Dibromo-1,1′-bi-2-naphthol), if you are interested, you can check out my other related articles.

Reference:
Bromide – Wikipedia,
bromide – Wiktionary

Du, Haifeng; Zhang, Xue; Wang, Zheng; Ding, Kuiling published an article about the compound: (S)-3,3′-Dibromo-1,1′-bi-2-naphthol( cas:119707-74-3,SMILESS:OC1=C(Br)C=C2C=CC=CC2=C1C3=C4C=CC=CC4=CC(Br)=C3O ).Electric Literature of C20H12Br2O2. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:119707-74-3) through the article.

This paper describes the successful development of a series of chiral zinc catalysts containing (R)-3,3′-Br2-BINOL ligand and various diimine activators for enantioselective HDA reaction of Danishefsky’s diene with aldehydes through a combinatorial approach, affording the corresponding 2,3-dihydro-4H-pyran-4-one derivatives in excellent yields and enantioselectivities. The application of this type of catalysis was also extended to the diethylzinc addition to the benzaldehyde, affording the corresponding secondary alc. with up to 94.5% ee under optimized conditions. On the basis of these facts, the integration of two distinct enantioselective reactions, HDA and diethylzinc addition reactions, has been realized in one-pot with the promotion of a single chiral zinc catalyst in a sequential manner. The impact of diimine additive on the catalytic system of HDA reaction was also investigated by probing the nonlinear effect of reaction system. The pos. nonlinear effect exhibited in the catalytic system could be attributed to the poor solubility of the heterochiral zinc species. On the basis of various exptl. findings disclosed in this research, a possible mechanism for the asym. induction in the 3,3′-Br2-BINOL/Zn/diimine catalyzed enantioselective HDA reaction of Danishefsky’s diene with aldehydes was outlined.

From this literature《One catalyst for two distinct reactions: sequential asymmetric hetero Diels-Alder reaction and diethylzinc addition》,we know some information about this compound(119707-74-3)Electric Literature of C20H12Br2O2, but this is not all information, there are many literatures related to this compound(119707-74-3).

Reference:
Bromide – Wikipedia,
bromide – Wiktionary

Formula: C20H12Br2O2. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: (S)-3,3′-Dibromo-1,1′-bi-2-naphthol, is researched, Molecular C20H12Br2O2, CAS is 119707-74-3, about Chiral amino alcohols via catalytic enantioselective Petasis borono-Mannich reactions. Author is Kavouris, John A.; Kavouris, Kathryn E.; Wambua, Victor; Demerzhan, Roman; Moquist, Philip N.; Vetticatt, Mathew J.; Schaus, Scott E..

Chiral amino alcs. are valuable building blocks in the synthesis of drugs, natural products, and chiral ligands used in enantioselective catalysis. The Petasis borono-Mannich reaction is a multicomponent condensation reaction of aldehydes, amines, and boronic acids to afford chiral amines. This report describes a practical, easily scaled, enantioselective Petasis borono-Mannich reaction of glycolaldehyde, with primary or secondary amines, and boronates catalyzed by BINOL-derived catalysts to afford chiral 1,2-amino alcs. in high yields and enantioselectivities. The reactions are executed at room temperature in ethanol or trifluorotoluene using com. available reagents and leverage an inherently attractive feature of the multicomponent reaction; the ability to use amines and boronates that possess a wide range of structural and electronic properties. Computational modeling of the diastereomeric transition states using DFT calculations identified a non-conventional CH···O interaction as a key feature that selectively stabilizes the transition state leading to the major enantiomer. The enantioselective catalytic reaction exemplifies a truly practical multicomponent condensation to afford 1,2-amino alcs. in highly enantioenriched form.

From this literature《Chiral amino alcohols via catalytic enantioselective Petasis borono-Mannich reactions》,we know some information about this compound(119707-74-3)Formula: C20H12Br2O2, but this is not all information, there are many literatures related to this compound(119707-74-3).

Reference:
Bromide – Wikipedia,
bromide – Wiktionary

Quality Control of (S)-3,3′-Dibromo-1,1′-bi-2-naphthol. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: (S)-3,3′-Dibromo-1,1′-bi-2-naphthol, is researched, Molecular C20H12Br2O2, CAS is 119707-74-3, about Catalytic Asymmetric Intramolecular Hydroacylation with Rhodium/Phosphoramidite-Alkene Ligand Complexes. Author is Hoffman, Thomas J.; Carreira, Erick M..

An asym. intramol. Rh-catalyzed hydroacylation reaction of pent-4-enals for the preparation of functionalized cyclopentanones in good yield and high enantioselectivity is described (I → II; R = e.g., alkyl, aryl). This process uses rhodium complexes featuring novel modular phosphoramidite-alkene ligands and achiral phosphine coligands.

From this literature《Catalytic Asymmetric Intramolecular Hydroacylation with Rhodium/Phosphoramidite-Alkene Ligand Complexes》,we know some information about this compound(119707-74-3)Quality Control of (S)-3,3′-Dibromo-1,1′-bi-2-naphthol, but this is not all information, there are many literatures related to this compound(119707-74-3).

Reference:
Bromide – Wikipedia,
bromide – Wiktionary

The chemical properties of alicyclic heterocycles are similar to those of the corresponding chain compounds. Compound: (S)-3,3′-Dibromo-1,1′-bi-2-naphthol, is researched, Molecular C20H12Br2O2, CAS is 119707-74-3, about Asymmetric catalysts for helix-sense selective carbodiimide polymerizations, the main research direction is titanium catalyst helix sense selective carbodiimide polymerization.Product Details of 119707-74-3.

A family of active highly enantioselective titanium catalysts was used for the helix-sense selective polymerization of carbodiimides. The polymer produced were chiral and optically active due only to the predominance of one helical sense over the other.

From this literature《Asymmetric catalysts for helix-sense selective carbodiimide polymerizations》,we know some information about this compound(119707-74-3)Product Details of 119707-74-3, but this is not all information, there are many literatures related to this compound(119707-74-3).

Reference:
Bromide – Wikipedia,
bromide – Wiktionary

Reference of (S)-3,3′-Dibromo-1,1′-bi-2-naphthol. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: (S)-3,3′-Dibromo-1,1′-bi-2-naphthol, is researched, Molecular C20H12Br2O2, CAS is 119707-74-3, about Lewis Acid Catalysis and Ligand Exchange in the Asymmetric Binaphthol-Catalyzed Propargylation of Ketones. Author is Grayson, Matthew N.; Goodman, Jonathan M..

1,1′-Bi-2-naphthol (BINOL)-derived catalysts catalyze the asym. propargylation of ketones. D. functional theory (DFT) calculations show that the reaction proceeds via a closed six-membered transition structure (TS) in which the chiral catalyst undergoes an exchange process with the original cyclic boronate ligand. This leads to a Lewis acid type activation mode, not a Bronsted acid process, which accurately predicts the stereochem. outcome observed exptl.

In some applications, this compound(119707-74-3)Reference of (S)-3,3′-Dibromo-1,1′-bi-2-naphthol is unique.If you want to know more details about this compound, you can contact with the author or consult more relevant literature.

Reference:
Bromide – Wikipedia,
bromide – Wiktionary

Most of the compounds have physiologically active properties, and their biological properties are often attributed to the heteroatoms contained in their molecules, and most of these heteroatoms also appear in cyclic structures. A Journal, Article, Research Support, Non-U.S. Gov’t, Journal of the American Chemical Society called Michael Reaction Inspired Atroposelective Construction of Axially Chiral Biaryls, Author is Yan, Shengyi; Xia, Wang; Li, Shaoyu; Song, Qiuling; Xiang, Shao-Hua; Tan, Bin, which mentions a compound: 119707-74-3, SMILESS is OC1=C(Br)C=C2C=CC=CC2=C1C3=C4C=CC=CC4=CC(Br)=C3O, Molecular C20H12Br2O2, Synthetic Route of C20H12Br2O2.

The first copper-catalyzed atroposelective Michael-type addition between azonaphthalenes and arylboronic acids for the construction of biaryl atropisomers was established using a novel BINOL-derived phosphoramidite as a chiral ligand. A broad range of atropisomeric biaryls were obtained with good efficiency, and the practicality of this approach was verified by versatile transformations toward axially chiral ligands, catalysts, and other functional atropisomers. This set of catalytic systems successfully inhibited the routine 1,2-addition and promoted the formation of an aryl-aryl chiral axis. Meanwhile, this strategy bypassed the use of an oxidant as well as the harsh conditions normally necessary for transition-metal-mediated arene C-H coupling with arylboronic acids as an arylation counterpart, offering a straightforward alternative to access optically active biaryls.

When you point to this article, it is believed that you are also very interested in this compound(119707-74-3)Synthetic Route of C20H12Br2O2 and due to space limitations, I can only present the most important information.

Reference:
Bromide – Wikipedia,
bromide – Wiktionary

Application In Synthesis of (S)-3,3′-Dibromo-1,1′-bi-2-naphthol. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: (S)-3,3′-Dibromo-1,1′-bi-2-naphthol, is researched, Molecular C20H12Br2O2, CAS is 119707-74-3, about Highly efficient enantioselective epoxidation of α,β-enones catalyzed by cheap chiral lanthanum and gadolinium alkoxides. Author is Chen, Ruifang; Qian, Changtao; de Vries, Johannes G..

(S)-6,6′-Dibromo-BINOL and (S)-6,6′-diphenyl-BINOL have been developed as efficient chiral ligands applicable to lanthanoid catalyzed asym. epoxidation of α,β-unsaturated ketones in the presence of cumene hydroperoxide. Excellent chem. yield and enantioselectivity have been achieved for several epoxides, e.g., I, at room temperature by using 5 mol% of La(O-i-Pr)3-(S)-6,6′-dibromo-BINOL and Gd(O-i-Pr)3-(S)-6,6′-diphenyl-BINOL, resp. Up to 95% ee was obtained for epoxychalcone with Gd(O-i-Pr)3-(S)-6,6-diphenyl-BINOL catalyst at room temperature A plausible catalyst structure as well as the catalytic cycle has also been suggested.

When you point to this article, it is believed that you are also very interested in this compound(119707-74-3)Application In Synthesis of (S)-3,3′-Dibromo-1,1′-bi-2-naphthol and due to space limitations, I can only present the most important information.

Reference:
Bromide – Wikipedia,
bromide – Wiktionary

Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: (S)-3,3′-Dibromo-1,1′-bi-2-naphthol, is researched, Molecular C20H12Br2O2, CAS is 119707-74-3, about Catalytic enantioselective trapping of an alcoholic oxonium ylide with aldehydes: RhII/ZrIV-Co-catalyzed three-component reactions of aryl diazoacetates, benzyl alcohol, and aldehydes.Application In Synthesis of (S)-3,3′-Dibromo-1,1′-bi-2-naphthol.

A catalytic asym. multicomponent reaction has been developed in which two stereogenic carbon centers are constructed in a single step. This type of enantioselective three-component reaction generates α,β-dihydroxy acid derivatives, e.g. (2S,3S)-PhCH(OH)CPh(OBn)CO2Me, in good yields and with excellent enantioselectivities.

When you point to this article, it is believed that you are also very interested in this compound(119707-74-3)Application In Synthesis of (S)-3,3′-Dibromo-1,1′-bi-2-naphthol and due to space limitations, I can only present the most important information.

Reference:
Bromide – Wikipedia,
bromide – Wiktionary