Tag: M.W=250-300

Yao, Zhaoyang published the artcileConformational and compositional tuning of phenanthrocarbazole-based dopant-free hole-transport polymers boosting performance of perovskite solar cells, Quality Control of 303734-52-3, the publication is Journal of the American Chemical Society (2020), 142(41), 17681-17692, database is CAplus and MEDLINE.

Conjugated polymers are regarded as promising candidates for dopant-free hole-transport materials (HTMs) in efficient and stable perovskite solar cells (PSCs). Thus far, the vast majority of polymeric HTMs feature structurally complicated benzo[1,2-b:4,5-b′]dithiophene (BDT) analogs and electron-withdrawing heterocycles, forming a strong donor-acceptor (D-A) structure. Herein, a new class of phenanthrocarbazole (PC)-based polymeric HTMs (PC1, PC2, and PC3) has been synthesized by inserting a PC unit into a polymeric thiophene or selenophene chain with the aim of enhancing the π-π stacking of adjacent polymer chains and also to efficiently interact with the perovskite surface through the broad and planar conjugated backbone of the PC. Suitable energy levels, excellent thermostability, and humidity resistivity together with remarkable photoelec. properties are obtained via meticulously tuning the conformation and elemental composition of the polymers. As a result, PSCs containing PC3 as dopant-free HTM show a stabilized power conversion efficiency (PCE) of 20.8% and significantly enhanced longevity, rendering one of the best types of PSCs based on dopant-free HTMs. Subsequent exptl. and theor. studies reveal that the planar conformation of the polymers contributes to an ordered and face-on stacking of the polymer chains. Furthermore, introduction of the “Lewis soft” selenium atom can passivate surface trap sites of perovskite films by Pb-Se interaction and facilitate the interfacial charge separation significantly. This work reveals the guiding principles for rational design of dopant-free polymeric HTMs and also inspires rational exploration of small mol. HTMs.

Journal of the American Chemical Society published new progress about 303734-52-3. 303734-52-3 belongs to bromides-buliding-blocks, auxiliary class Thiophene,Bromide, name is 2-Bromo-3-(2-ethylhexyl)thiophene, and the molecular formula is C18H17NO8, Quality Control of 303734-52-3.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Gao, Heqi published the artcileA dentin hypersensitivity treatment using highly stable photothermal conversion nanoparticles, Name: 2-Bromo-3-(2-ethylhexyl)thiophene, the publication is Materials Chemistry Frontiers (2021), 5(8), 3388-3395, database is CAplus.

Most of the currently available com. photothermal agents suffer from issues in terms of photothermal instability and low photothermal conversion efficiency (PCE), which indeed impair their practical applications in disease treatment. Herein, a type of biocompatible organic nanoparticles (namely NDTB NPs) for an effective photothermal treatment with a high PCE of 40.6% was developed, which showed far higher photothermal stability compared with that of the clin. used indocyanine green. In addition, NDTB NPs combined with laser are significantly more effective than only laser irradiation in phototheranostic dental hypersensitivity treatments. This study thus provides an insight into the development of advanced photothermal NPs for practical phototheranostic applications.

Materials Chemistry Frontiers published new progress about 303734-52-3. 303734-52-3 belongs to bromides-buliding-blocks, auxiliary class Thiophene,Bromide, name is 2-Bromo-3-(2-ethylhexyl)thiophene, and the molecular formula is C12H19BrS, Name: 2-Bromo-3-(2-ethylhexyl)thiophene.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Barasa, Leonard published the artcileAn Efficient Chemo-Selective N-Alkylation Methodology for the Structure Diversification of Indolylbenzimidazoles, Quality Control of 21101-63-3, the publication is ChemistrySelect (2020), 5(11), 3173-3178, database is CAplus.

A simple and efficient methodol. for the chemoselective N-alkylation of indolylbenzimidazole scaffolds was reported. This approach took advantage of the pKa differences between indole and benzimidazole nitrogen to achieve desired chemo-selectivity. Using the reported method, one could readily access a selection of mono-N-alkylated indolylbenzimidazoles I [R = Me, CH₂CH=CH₂, Bn, etc.; R¹ = H, OMe] or asym. bis-alkylated indolylbenzimidazoles II [R² = Me, C≡CH, cyclopropyl, Ph; R³ = Me, C≡CH, cyclopropyl] in a simple one-pot operation. Moreover, this method provided the desired products in excellent yield and demonstrated a broad substrate scope.

ChemistrySelect published new progress about 21101-63-3. 21101-63-3 belongs to bromides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Bromide,sulfides,Benzyl bromide,Benzene, name is (4-(Bromomethyl)phenyl)(trifluoromethyl)sulfane, and the molecular formula is C8H6BrF3S, Quality Control of 21101-63-3.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Kim, Ki-Hyun published the artcileInfluence of intermolecular interactions of electron donating small molecules on their molecular packing and performance in organic electronic devices, Synthetic Route of 303734-52-3, the publication is Journal of Materials Chemistry A: Materials for Energy and Sustainability (2013), 1(46), 14538-14547, database is CAplus.

Intermol. interactions have a critical role in determining the mol. packing and orientation of conjugated polymers and organic mols., leading to significant changes in their elec. and optical properties. Herein, the authors studied the effects of intermol. interactions of electron-donating small mols. on their structural, optical, and elec. properties, as well as on their performance in organic field-effect transistors (OFETs) and organic photovoltaics (OPVs). Dithienosilole-based small mol. donors were synthesized by introducing different terminal groups of ester and amide groups combined with 3 different versions of alkyl side chains. In comparison to dithienosilole-based small mols. with ester terminal groups, those with amide terminal groups exhibit strong intermol. interaction by H bonding in a nondestructive manner. To control the intermol. distance during assembly and thus fine-tune the interaction between the small mol. donors, 3 different alkyl side chains (i.e., n-octyl, n-decyl, and 2-ethylhexyl chains) were introduced into both small mols. with amide and ester terminal groups. The mol. packing and orientation of the small mol. donors were dramatically changed upon modifying the terminal groups and the alkyl side chains, as evidenced by grazing incidence x-ray scattering (GIXS) measurements. This feature significantly affected the elec. properties of the small mols. in OFETs. The trends in the activation energies for charge transport and the hole mobilities in OFETs were consistent with the mol. ordering and orientation propensity. The nano-scale morphol. of small mols. blended with [6,6]-phenyl-C₆₁-butyric acid Me ester (PCBM) was also influenced by the intermol. interaction of small mol. donors. Power conversion efficiencies of >4.3% in OPVs were obtained from dithienosilole-based small mols. with ester terminal groups and linear side chains due to the optimized intermol. interaction and morphol. of the active layer.

Journal of Materials Chemistry A: Materials for Energy and Sustainability published new progress about 303734-52-3. 303734-52-3 belongs to bromides-buliding-blocks, auxiliary class Thiophene,Bromide, name is 2-Bromo-3-(2-ethylhexyl)thiophene, and the molecular formula is C12H19BrS, Synthetic Route of 303734-52-3.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Correy, Galen J. published the artcileOvercoming insecticide resistance through computational inhibitor design, Application of (3-Bromo-5-isopropoxyphenyl)boronic acid, the publication is Proceedings of the National Academy of Sciences of the United States of America (2019), 116(42), 21012-21021, database is CAplus and MEDLINE.

Insecticides allow control of agricultural pests and disease vectors and are vital for global food security and health. The evolution of resistance to insecticides, such as organophosphates (OPs), is a serious and growing concern. OP resistance often involves sequestration or hydrolysis of OPs by carboxylesterases. Inhibiting carboxylesterases could, therefore, restore the effectiveness of OPs for which resistance has evolved. Here, we use covalent virtual screening to produce nano-/picomolar boronic acid inhibitors of the carboxylesterase αE7 from the agricultural pest Lucilia cuprina as well as a common Gly137Asp αE7 mutant that confers OP resistance. These inhibitors, with high selectivity against human acetylcholinesterase and low to no toxicity in human cells and in mice, act synergistically with the OPs diazinon and malathion to reduce the amount of OP required to kill L. cuprina by up to 16-fold and abolish resistance. The compounds exhibit broad utility in significantly potentiating another OP, chlorpyrifos, against the common pest, the peach-potato aphid (Myzus persicae). These compounds represent a solution to OP resistance as well as to environmental concerns regarding overuse of OPs, allowing significant reduction of use without compromising efficacy.

Proceedings of the National Academy of Sciences of the United States of America published new progress about 871125-81-4. 871125-81-4 belongs to bromides-buliding-blocks, auxiliary class Bromide,Boronic acid and ester,Benzene,Ether,Boronic Acids,Boronic acid and ester, name is (3-Bromo-5-isopropoxyphenyl)boronic acid, and the molecular formula is C9H12BBrO3, Application of (3-Bromo-5-isopropoxyphenyl)boronic acid.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Cary, Douglas R. published the artcileRhenium bipyridine complexes for the recognition of glucose, Recommanded Product: 2-(2-(Bromomethyl)phenyl)-5,5-dimethyl-1,3,2-dioxaborinane, the publication is Inorganic Chemistry (2002), 41(6), 1662-1669, database is CAplus and MEDLINE.

Bipyridine ligands containing pendant Me, amino, and amino-boronic acid groups were synthesized. Coordination complexes of these ligands with rhenium were prepared straightforwardly and in good yield. The fluorescence behavior of the Re complexes was studied as a function of pH and exposure to various concentrations of glucose. The Me bipyridine complex showed no change in fluorescence with pH, the amino derivative showed a rapid decrease from low pH to neutral, and the amino-boronate derivative showed little change from pH 4 to 10. Fluorescence quenching was observed at high pH as expected on the basis of a photoinduced electron transfer (PET) signaling mechanism. This behavior can be explained on the basis of the first oxidation and reduction potentials of these complexes. Glucose testing showed a significant dependence on the solvent system used. In pure methanol, the rhenium boronate complex exhibited a 55% fluorescence intensity increase upon increasing glucose concentration from 0 to 400 mg/dL. However, in 50 vol % methanol/phosphate buffered saline, none of the complexes showed significant response in the glucose range of physiol. interest.

Inorganic Chemistry published new progress about 166821-88-1. 166821-88-1 belongs to bromides-buliding-blocks, auxiliary class Bromide,Boronic acid and ester,Benzyl bromide,Benzene,Boronic Acids,Boronic acid and ester, name is 2-(2-(Bromomethyl)phenyl)-5,5-dimethyl-1,3,2-dioxaborinane, and the molecular formula is C12H16BBrO2, Recommanded Product: 2-(2-(Bromomethyl)phenyl)-5,5-dimethyl-1,3,2-dioxaborinane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Grand, Caroline published the artcileMorphology Control in Films of Isoindigo Polymers by Side-Chain and Molecular Weight Effects, Category: bromides-buliding-blocks, the publication is ACS Applied Materials & Interfaces (2017), 9(15), 13357-13368, database is CAplus and MEDLINE.

The performance of devices relying on organic electronic materials, such as organic field-effect transistors (OFET) and organic photovoltaics (OPV), is strongly correlated to the morphol. of the conjugated material in thin films. For instance, several factors such as polymer solubility, weak intermol. forces between polymers and fullerene derivatives, and film drying time impact phase separation in the active layer of a bulk heterojunction OPV device. In an effort to probe the influence of polymer assembly on morphol. of polymer thin films and phase separation with fullerene derivatives, five terthiophene-alt-isoindigo copolymers were synthesized with alkyl side-chains of varying lengths and branching on the terthiophene unit. These P[T3(R)-iI] polymers were designed to have similar optoelectronic properties but different solubilities in o-dichlorobenzene and were predicted to have different tendencies for crystallization All polymers with linear alkyl chains exhibit similar thin film morphologies as investigated by grazing-incidence wide-angle X-ray scattering (GIWAXS) and at. force microscopy (AFM). The main differences in electronic and morphol. properties arise when P[T3(R)-iI] is substituted with branched 2-ethylhexyl (2EH) side-chains. The bulky 2EH substituents lead to a blue-shifted absorption, a lower ionization potential, and reduced ordering in polymer thin films. The five P[T3-iI] derivatives span hole mobilities from 1.5 × 10^-3 to 2.8 × 10^-2 cm² V^-1 s^-1 in OFET devices. In OPV devices, the 2EH-substituted polymers yield open-circuit voltages of 0.88 V in BHJ devices yet low short-circuit currents of 0.8 mA cm^-2, which is explained by the large phase separation observed by AFM in blends of P[T3(2EH)-iI] with PC₇₁BM. In these P[T3(R)-iI] systems, the propensity for the polymers to self-assemble prior to aggregation of PC₇₁BM mols. was key to achieving fine phase separation and increased short-circuit currents, eventually resulting in power conversion efficiencies of 5% in devices processed using a single solvent.

ACS Applied Materials & Interfaces published new progress about 303734-52-3. 303734-52-3 belongs to bromides-buliding-blocks, auxiliary class Thiophene,Bromide, name is 2-Bromo-3-(2-ethylhexyl)thiophene, and the molecular formula is C12H19BrS, Category: bromides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Caldirola, P. published the artcileNew prenylamine-analogs: investigations of their influence on calcium-dependent biological systems, Quality Control of 1997-80-4, the publication is European Journal of Medicinal Chemistry (1993), 28(7-8), 555-68, database is CAplus.

Chem., prenylamine belongs to the diphenylalkylamine class. Compounds of this class are calcium antagonists with a broad spectrum of activities due to their influence on both extracellular and intracellular sites. In the present study the calcium antagonistic profile of a recently developed new series of prenylamine analogs has been investigated using different in vitro systems. The inhibiting concentrations for the most active compound are ≈ 1.5 μM; several derivatives are inactive up to a concentration of 10 μM. Structural modifications towards an increase of lipophilicity make these mols. interact (inhibition) with the intracellular calcium-binding protein calmodulin; for the series no correlation between calcium-blocking and calmodulin antagonistic effects has been found.

European Journal of Medicinal Chemistry published new progress about 1997-80-4. 1997-80-4 belongs to bromides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Bromide,Benzene, name is 1-(2-Bromoethyl)-3-(trifluoromethyl)benzene, and the molecular formula is C9H8BrF3, Quality Control of 1997-80-4.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Liu, Delong published the artcileTunable Electron Donating and Accepting Properties Achieved by Modulating the Steric Hindrance of Side Chains in A-D-A Small-Molecule Photovoltaic Materials, Formula: C12H19BrS, the publication is Chemistry of Materials (2018), 30(3), 619-628, database is CAplus.

Modulation of the electron donating and accepting properties of organic semiconductors is an important topic in the field of organic photovoltaics. Although the small-mol. semiconductors (SMs) with an A-D-A structure can act as either electron donor or acceptor in organic photovoltaic (OPV) devices, the reason why mols. with similar conjugated structures play different roles remains unclear. In this work, we designed and synthesized two A-D-A SMs named BTCN-O and BTCN-M, which have an identical backbone and differ in the alkyl substitution position. BTCN-O and BTCN-M demonstrate similar optical absorption spectra in solution and mol. energy levels in a solid film. BTCN-O forms an ordered lamellar packed structure with compact π-π stacking, whereas BTCN-M demonstrates only a weak π-π stacking effect in solid film. We also investigated their photovoltaic properties by blending each with a polymer donor, PBDB-T, and a fullerene acceptor, PC₇₁BM, and found that the electron donating and accepting abilities of BTCN-O and BTCN-M are exactly opposite. According to the results obtained from a variety of anal. methods, we can infer that for the planar A-D-A SMs, the steric hindrance caused by the nonconjugated alkyls in their central units plays a critical role that affects their electron donating and accepting properties. More specifically, the A-D-A mols. that have low steric hindrance in their central units, which allows ordered lamellar packing and compact π-π stacking in the solid film, can act as an electron donor in OPV device, and the mols. that have high steric hindrance for intermol. π-π interactions in their central units tend to act as electron acceptors. Overall, this work provides a new perspective in the mol. design of organic photovoltaic materials.

Chemistry of Materials published new progress about 303734-52-3. 303734-52-3 belongs to bromides-buliding-blocks, auxiliary class Thiophene,Bromide, name is 2-Bromo-3-(2-ethylhexyl)thiophene, and the molecular formula is C12H19BrS, Formula: C12H19BrS.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Dutta, Shubham published the artcileKeteniminium-Driven Umpolung Difunctionalization of Ynamides, Application In Synthesis of 1228180-83-3, the publication is Angewandte Chemie, International Edition (2020), 59(27), 10785-10790, database is CAplus and MEDLINE.

A three-component Pd-catalyzed coupling of ynamides, aryl diazonium salts, and aryl boronic acids for the synthesis of novel triaryl-substituted enamides is described. This transformation represents the first example of an umpolung regioselective unsym. syn-1,2-diarylation/aryl-olefination of ynamides. The aryl moieties of the diazonium salt (electrophile) and boronic acid (nucleophile) are explicitly incorporated in the electrophilic α- and nucleophilic β-position, resp., of the ynamide, resulting in a single isomer of the N-bearing tetrasubstituted olefin. The scope is broad (68 examples), showing excellent functional-group tolerance. DFT calculations substantiate the rationale of the mechanistic cycle and the regioselectivity. The chemoselectivity and synthetic potential of the enamide products were also studied.

Angewandte Chemie, International Edition published new progress about 1228180-83-3. 1228180-83-3 belongs to bromides-buliding-blocks, auxiliary class Bromide,Boronic acid and ester,Benzene,Boronic Acids, name is 3,4-Dibromophenylboronic acid, and the molecular formula is C6H5BBr2O2, Application In Synthesis of 1228180-83-3.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary