Tag: M.W=200-350

Pindzola, Bradford A. published the artcilePolymerization of a Phosphonium Diene Amphiphile in the Regular Hexagonal Phase with Retention of Mesostructure, Application In Synthesis of 56523-59-2, the main research area is phosphonium diene amphiphile liquid crystal polymerization; tetradecadienyltrimethylphosphonium bromide preparation polymerization liquid crystal.

Three phosphonium diene mesogens were prepared from the corresponding ω-bromoalkyldienes by reaction with tri-Me phosphine in 2-propanol at 85°. Tetradeca-11,13-dienyltrimethylphosphonium bromide demonstrated the best lyotropic liquid crystal behavior and could be homopolymerized or copolymerized with divinylbenzene in the H1 phase with retention of the mesostructure.

Journal of the American Chemical Society published new progress about Liquid crystals, lyotropic. 56523-59-2 belongs to class bromides-buliding-blocks, name is 15-Bromopentadecanoic acid, and the molecular formula is C15H29BrO2, Application In Synthesis of 56523-59-2.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

An, Peng published the artcileSterically Shielded, Stabilized Nitrile Imine for Rapid Bioorthogonal Protein Labeling in Live Cells, Recommanded Product: Methyl 3,5-dibromo-4-methylbenzoate, the main research area is stabilized nitrile imine bioorthogonal protein labeling mammalian cell.

In pursuit of fast bioorthogonal reactions, reactive moieties have been increasingly employed for selective labeling of biomols. in living systems, posing a challenge in attaining reactivity without sacrificing selectivity. To address this challenge, here the authors report a bioinspired strategy in which mol. shape controls the selectivity of a transient, highly reactive nitrile imine dipole. By tuning the shape of structural pendants attached to the ortho position of the N-aryl ring of diaryltetrazoles, precursors of nitrile imines, the authors discovered a sterically shielded nitrile imine that favors the 1,3-dipolar cycloaddition over the competing nucleophilic addition The photogenerated nitrile imine exhibits an extraordinarily long half-life of 102 s in aqueous medium, owing to its unique mol. shape that hinders the approach of a nucleophile as shown by DFT calculations The utility of this sterically shielded nitrile imine in rapid (∼1 min) bioorthogonal labeling of glucagon receptor in live mammalian cells was demonstrated.

Journal of the American Chemical Society published new progress about 1,3-Dipolar cycloaddition reaction. 74896-66-5 belongs to class bromides-buliding-blocks, name is Methyl 3,5-dibromo-4-methylbenzoate, and the molecular formula is C9H8Br2O2, Recommanded Product: Methyl 3,5-dibromo-4-methylbenzoate.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Chen, Xiaoping published the artcileMolecular diodes with rectification ratios exceeding 105 driven by electrostatic interactions, COA of Formula: C15H29BrO2, the main research area is mol diode rectification ratio electrostatic interaction.

Mol. diodes operating in the tunnelling regime are intrinsically limited to a maximum rectification ratio R of ∼103. To enhance this rectification ratio to values comparable to those of conventional diodes (R ≥ 105) an alternative mechanism of rectification is therefore required. Here, the authors report a mol. diode with R = 6.3 × 105 based on self-assembled monolayers with Fc-C≃C-Fc (Fc, ferrocenyl) termini. The number of mols. (n(V)) involved in the charge transport changes with the polarity of the applied bias. More specifically, n(V) increases at forward bias because of an attractive electrostatic force between the pos. charged Fc units and the neg. charged top electrode, but remains constant at reverse bias when the Fc units are neutral and interact weakly with the pos. charged electrode. The authors successfully model this mechanism using mol. dynamics calculations

Nature Nanotechnology published new progress about Activation energy (of conductivity). 56523-59-2 belongs to class bromides-buliding-blocks, name is 15-Bromopentadecanoic acid, and the molecular formula is C15H29BrO2, COA of Formula: C15H29BrO2.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Crescenzi, Manuela published the artcileIon association and reactivity of the alkali metal salts of alkanoic acids in dipolar aprotic solvents, Recommanded Product: 15-Bromopentadecanoic acid, the main research area is ion association lactonization kinetics; carboxylic acid lactonization alkali metal ion.

The effect of added alkali metal perchlorates on the rate of lactonization of ω-bromoalkanoate ions was investigated in 99% DMSO (4-membered ring formation) and in DMF (4- and 16-membered ring formation). In all cases, the effect of the added metal salts is rate depressing, as a result of the lower reactivity of metal ion-associated species relative to the free ions. Ion-pairing association constants were determined, but the reactivity of ion pairs was so low as to elude direct measurement in most cases. Evidence was also obtained for the formation of ion triplets with Li+ in DMF. The relevance of the present results in connection with the cesium effect is briefly discussed.

Journal of Physical Organic Chemistry published new progress about Alkali metal ions Role: PRP (Properties). 56523-59-2 belongs to class bromides-buliding-blocks, name is 15-Bromopentadecanoic acid, and the molecular formula is C15H29BrO2, Recommanded Product: 15-Bromopentadecanoic acid.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Hossain, Muhammad Saddam published the artcileEffects of Self-Assembly on the Photogeneration of Radical Cations in Halogenated Triphenylamines, Recommanded Product: 4-(Bromomethyl)-N,N-diphenylaniline, the main research area is self Assembly photogeneration radical cation halogenated triphenylamines; crstal structure urea tethered TPA derivatives.

We investigate the effect of assembly on charge transfer, charge recombination, and the persistence of radical cations in halogen-substituted triphenylamine (TPA) dimers. A series of urea-tethered TPA derivatives, R-NH-CO-NH-R (R = X-p-C6H4-N(Ph)-p-C6H4-CH2-, X = H, Cl, Br, and I)(1X) are compared, which have one Ph group modified at the para position with a halogen. Ureas direct the assembly of these derivatives while halogen substituents influence the packing of the TPA units. These modifications affect the generation and persistence of TPA radical cations as monitored by ESR (EPR) spectroscopy. The formation and degradation pathways of the radical cations in solution and gas phase were probed by ion-mobility spectrometry mass spectrometry. In contrast, supramol. assembly enhanced the stability of these materials as well as the persistence of their photogenerated radical cations, which appear to undergo charge recombination without degradation Greater quantities of these radical cations are observed for the bromo and non-halogenated derivatives (1Br, 1H). Time-dependent d. functional theory (TD-DFT) calculations on single mols. and hydrogen-bonded dimers suggest the stability of TPA radical cations largely depends on initial photoinduced charge separation and electronic coupling between assembled TPA dimers. The latter was found to be about 7 times stronger in 1I than in 1Br dimers, which may explain faster charge recombination and shorter lifetimes of 1I radicals. Transient absorption (TA) spectroscopy and TD-DFT were able to identify the charged species for 1Br along with the kinetic traces and measured lifetime of ~80 ns. Fluorescence quenching studies are consistent with initial charge separation and subsequent charge transfer event between nearby TPAs. Future exploration will focus on the mobility and application of these TPA assemblies as hole transport materials.

Journal of Physical Chemistry C published new progress about Charge separation (photoinduced, electron hole pair). 183994-94-7 belongs to class bromides-buliding-blocks, name is 4-(Bromomethyl)-N,N-diphenylaniline, and the molecular formula is C19H16BrN, Recommanded Product: 4-(Bromomethyl)-N,N-diphenylaniline.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Cabre, Albert published the artcileHighly Enantioselective Iridium-Catalyzed Hydrogenation of 2-Aryl Allyl Phthalimides, Recommanded Product: (R)-tert-Butyl (2-(4-bromophenyl)propyl)carbamate, the main research area is beta aryl methyl amine preparation enantioselective; aryl allyl phthalimide hydrogenation iridium catalyst.

The iridium-catalyzed asym. hydrogenation of 2-aryl allyl phthalimides to afford enantioenriched β-aryl-β-Me amines is presented. Recently developed Ir-MaxPHOX catalysts are used for this enantioselective transformation. The mild reaction conditions and the feasible removal of the phthalimido group makes this catalytic method easily scalable and of great interest to afford chiral amines. The importance of this new methodol. is exemplified by the formal synthesis of (R)-Lorcaserin, OTS514, and enantiomerically enriched 3-Me indolines.

Organic Letters published new progress about Amines Role: SPN (Synthetic Preparation), PREP (Preparation). 211315-53-6 belongs to class bromides-buliding-blocks, name is (R)-tert-Butyl (2-(4-bromophenyl)propyl)carbamate, and the molecular formula is C14H20BrNO2, Recommanded Product: (R)-tert-Butyl (2-(4-bromophenyl)propyl)carbamate.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Ravi, S. published the artcileMacrocyclic musk compounds: Synthetic approaches to key intermediates for exaltolide, exaltone and dilactones, Name: 15-Bromopentadecanoic acid, the main research area is macrocyclic lactone exaltolide exaltone synthesis.

Facile syntheses to key intermediates 15-bromopentadecanoic acid and Me 15-hydroxypentadecanoate (for exaltolide), di-Me pentadecanedioate (for exaltone) and tridecanedioic acid and undecanedioic acid (for ethylene brassylate and cyclic ethylene undecanedioate), resp., was achieved from easily accessible aleuritic acid and 10-undecenoic acid.

Journal of the Indian Institute of Science published new progress about Lactones Role: SPN (Synthetic Preparation), PREP (Preparation). 56523-59-2 belongs to class bromides-buliding-blocks, name is 15-Bromopentadecanoic acid, and the molecular formula is C15H29BrO2, Name: 15-Bromopentadecanoic acid.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Hebeisen, Paul published the artcileRing opening of cyclic sulfamidates with bromophenyl metal reagents: complementarity of sulfamidates and aziridines, Related Products of bromides-buliding-blocks, the main research area is cyclic sulfamidate preparation aryl iodide derived Grignard ring opening; stereochem inversion regioselective ring opening.

Bromophenyl magnesium reagents generated via a Knochel type magnesium-halogen exchange of aryl iodides undergo regioselective ring opening of cyclic primary and secondary N-Boc sulfamidates in good to excellent yields. With secondary sulfamidates the reaction proceeds with clean inversion of the stereochem. This protocol complements the ring opening of aziridines with bromophenyl metal reagents and extends its scope to secondary substrates.

Tetrahedron Letters published new progress about Amino alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 211315-53-6 belongs to class bromides-buliding-blocks, name is (R)-tert-Butyl (2-(4-bromophenyl)propyl)carbamate, and the molecular formula is C14H20BrNO2, Related Products of bromides-buliding-blocks.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Cruz, Cole L. published the artcileNickel-catalyzed reductive coupling of unactivated alkyl bromides and aliphatic aldehydes, Formula: C14H20BBrO3, the main research area is aliphatic aldehyde alkyl bromide reductive coupling nickel catalyst; silyl secondary alc preparation.

A mild, convenient coupling of aliphatic aldehydes e.g., BnCH2CHO and unactivated alkyl bromides e.g., Br(CH2)3C(O)OEt has been developed. The catalytic system features the use of a common Ni(II) precatalyst and a readily available bioxazoline ligand and affords silyl-protected secondary alcs. e.g., BnCH2CH(OTES)(CH2)3C(O)OEt. The reaction is operationally simple, utilizes Mn as a stoichiometric reductant, and tolerates a wide range of functional groups. The use of 1,5-hexadiene as an additive is an important reaction parameter that provides significant benefits in yield optimizations. Initial mechanistic experiments support a mechanism featuring an alpha-silyloxy Ni species that undergoes formal oxidative addition to the alkyl bromide via a reductive cross-coupling pathway.

Chemical Science published new progress about Aliphatic aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 913836-27-8 belongs to class bromides-buliding-blocks, name is 2-(4-(2-Bromoethoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane, and the molecular formula is C14H20BBrO3, Formula: C14H20BBrO3.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Amano, Taisei published the artcileNew Strategy for Synthesis of Bis-Pocket Metalloporphyrins Enabling Regioselective Catalytic Oxidation of Alkanes, Application of Methyl 3,5-dibromo-4-methylbenzoate, the main research area is metalloporphyrin ruthenium double pocket preparation oxidation catalyst; alkane oxidation preparation alkanol alkanone ruthenium metalloporphyrin double pocket.

Meso-Quaterphenyl-substituted metalloporphyrins (bis-pocket porphyrins) were prepared; the ruthenium porphyrin undergoes oxidation to dioxoruthenium species, which catalyze oxidation of alkanes by pyridine N-oxides into alkanols and alkanones,. Cytochrome P 450 selectively hydroxylates the ω and ω-1 positions of fatty acids. Among synthetic oxidizing catalysts, Suslick’s bis-pocket porphyrin Mn or Fe complex achieved ω oxidation for the first time, but the yield in the preparation of the catalyst was poor due to steric hindrance, and in addition, the catalyst turnover number in the oxidation reaction was low. We have devised a new synthetic strategy involving the introduction of eight bulky aryl groups at the 2,6-positions of the meso-Ph groups after construction of the porphyrin skeleton. This strategy greatly improved the yield in synthesis of the catalyst, and a number of derivatives of bis-pocket porphyrin and their metal complexes were prepared These Ru complexes show unique ω-1 selectivity and provide a much higher turnover number in the oxidation of linear alkane with 2,6-dichloropyridine N-oxide, as compared to the reaction catalyzed by conventional Ru porphyrins.

Bulletin of the Chemical Society of Japan published new progress about Aliphatic alcohols Role: SPN (Synthetic Preparation), PREP (Preparation). 74896-66-5 belongs to class bromides-buliding-blocks, name is Methyl 3,5-dibromo-4-methylbenzoate, and the molecular formula is C9H8Br2O2, Application of Methyl 3,5-dibromo-4-methylbenzoate.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary