Tag: M.W=200-250

Niu, Ben’s team published research in Organic Letters in 24 | CAS: 143-15-7

Organic Letters published new progress about 143-15-7. 143-15-7 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromododecane, and the molecular formula is C12H25Br, Recommanded Product: 1-Bromododecane.

Niu, Ben published the artcilePhotoredox Polyfluoroarylation of Alkyl Halides via Halogen-Atom-Transfer, Recommanded Product: 1-Bromododecane, the publication is Organic Letters (2022), 24(3), 916-920, database is CAplus and MEDLINE.

The first polyfluoroarylation of unactivated alkyl halides RX (R = n-nonyl, cyclohexyl, adamantan-1-yl, 1-[(thiophen-2-yl)carbonyl]piperidin-4-yl, etc.; X = I, Br) e.g., I via halogen-atom-transfer process was described. This method converts primary, secondary, and tertiary alkyl halides into the resp. polyfluoroaryl compounds e.g., 3-(perfluorophenyl)butyl 4-methoxybenzoate in good yields in the presence of amide, carbamate, ester, aromatic and sulfonamide moieties including derivatives of complex bioactive mols. Mechanistic work revealed that this transformation proceeds through an alkyl radical generated after a halogen-atom-transfer.

Organic Letters published new progress about 143-15-7. 143-15-7 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromododecane, and the molecular formula is C12H25Br, Recommanded Product: 1-Bromododecane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Macmillan, Wm. Geo.’s team published research in Journal of the Chemical Society in | CAS: 53484-26-7

Journal of the Chemical Society published new progress about 53484-26-7. 53484-26-7 belongs to bromides-buliding-blocks, auxiliary class Bromide,Nitro Compound,Amine,Benzene, name is 4-Bromo-N-methyl-2-nitroaniline, and the molecular formula is C7H7BrN2O2, HPLC of Formula: 53484-26-7.

Macmillan, Wm. Geo. published the artcileFormation of N-nitrosoamines from tertiary amines. I. Conversion of derivatives of dimethylaniline by nitrous acid into the corresponding nitrosoamines and monomethylanilines, HPLC of Formula: 53484-26-7, the publication is Journal of the Chemical Society (1929), 2803-7, database is CAplus.

Abnormal reactions between HNO2 and tert. aromatic amines occur, leading to the formation of nuclear NO2 compounds by loss of H or halogens and N-nitrosoamines by loss of an alkyl group. With O2NC6H4NMe2, both types of reaction occur, the 2nd predominating at room temperature but often being accompanied by the 1st if the temperature is allowed to rise. 3-O2NC6H4NMe2 (10 g.), 30 cc. HCl and 70 cc. H2O and 25 cc. of 50% NaNO2 give 37% of the nitrosamine, 4 g. 3,4-(O2N)2C6H3NMe2 and 0.5 g. of the 3,6-di-NO2 derivative The 4-O2NC6H4NMe2 gives 46% of the nitrosamine, increased to 75% by the use of 4 times the HNO2. 3,6-(O2N)2C6H4NMe2 gives 73% of 3,6-dinitrophenyl-methylnitrosamine, orange, m. 128°. 4,3-Br(O2N)C6H3NMe2 gives 57% of 4-bromo-3-nitrophenylmethylnitrosamine, yellow, m. 78°, and a small amount of 3,4,6-Br(O2N)2C6H2-NMe2. 4,2-Br(O2N)C6H3NMe2 gives 80% of the corresponding nitrosamine, m. 73°. Hydrolysis with CO(NH2)2 and H2SO4 gives the corresponding monomethylanilines: 3,6-di-NO2, red, m. 163°; 4-bromo-3-nitro, claret, m. 81°; 4-bromo-2-nitro, orange, m. 103°; 4-bromo-2,6-dinitro, yellow, m. 106°.

Journal of the Chemical Society published new progress about 53484-26-7. 53484-26-7 belongs to bromides-buliding-blocks, auxiliary class Bromide,Nitro Compound,Amine,Benzene, name is 4-Bromo-N-methyl-2-nitroaniline, and the molecular formula is C7H7BrN2O2, HPLC of Formula: 53484-26-7.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Ronson, Thomas O.’s team published research in Angewandte Chemie, International Edition in 58 | CAS: 849062-12-0

Angewandte Chemie, International Edition published new progress about 849062-12-0. 849062-12-0 belongs to bromides-buliding-blocks, auxiliary class Bromide,Boronic acid and ester,Benzene,Ether,Boronic Acids,Boronic acid and ester, name is (3-Bromo-5-methoxyphenyl)boronic acid, and the molecular formula is C7H8BBrO3, SDS of cas: 849062-12-0.

Ronson, Thomas O. published the artcileRuthenium-Catalyzed Reductive Arylation of N-(2-Pyridinyl)amides with Isopropanol and Arylboronate Esters, SDS of cas: 849062-12-0, the publication is Angewandte Chemie, International Edition (2019), 58(2), 482-487, database is CAplus and MEDLINE.

A new three-component reductive arylation of amides with stable reactants (iPrOH and arylboronate esters), making use of a 2-pyridinyl (Py) directing group, is described. The N-Py-amide substrates are readily prepared from carboxylic acids and PyNH2, and the resulting N-Py-1-arylalkanamine reaction products are easily transformed into the corresponding chlorides by substitution of the HN-Py group with HCl. The 1-aryl-1-chloroalkane products allow substitution and cross-coupling reactions. Therefore, a general protocol for the transformation of carboxylic acids into a variety of functionalities is obtained. The Py-NH2 byproduct can be recycled.

Angewandte Chemie, International Edition published new progress about 849062-12-0. 849062-12-0 belongs to bromides-buliding-blocks, auxiliary class Bromide,Boronic acid and ester,Benzene,Ether,Boronic Acids,Boronic acid and ester, name is (3-Bromo-5-methoxyphenyl)boronic acid, and the molecular formula is C7H8BBrO3, SDS of cas: 849062-12-0.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Grant, Thomas M.’s team published research in Science of the Total Environment in 812 | CAS: 143-15-7

Science of the Total Environment published new progress about 143-15-7. 143-15-7 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromododecane, and the molecular formula is C12H25Br, Name: 1-Bromododecane.

Grant, Thomas M. published the artcileTowards eco-friendly marine antifouling biocides – Nature inspired tetrasubstituted 2,5-diketopiperazines, Name: 1-Bromododecane, the publication is Science of the Total Environment (2022), 152487, database is CAplus and MEDLINE.

Marine biofouling plagues all maritime industries at vast economic and environmental cost. Previous and most current methods to control biofouling have employed highly persistent toxins and heavy metals, including tin, copper, and zinc. These toxic methods are resulting in unacceptable environmental harm and are coming under immense regulatory pressure. Eco-friendly alternatives are urgently required to effectively mitigate the neg. consequence of biofouling without causing collateral harm. Amphiphilic micropeptides have recently been shown to exhibit excellent broad-spectrum antifouling activity, with a non-toxic mode of action and innate biodegradability. The present work focused on incorporating the pharmacophore derived from amphiphilic micropeptides into a 2,5-diketopiperazine (DKP) scaffold. This privileged structure is present in a vast number of natural products, including marine natural product antifoulants, and provides advantages of synthetic accessibility and adaptability. A novel route to sym. tetrasubstituted DKPs was developed and a library of amphiphilic 2,5-DKPs were subsequently synthesized. These biodegradable compounds were demonstrated to be potent marine antifoulants displaying broad-spectrum activity in the low micromolar range against a range of common marine fouling organisms. The outcome of planned coating and field trials will dictate the future development of the lead compounds

Science of the Total Environment published new progress about 143-15-7. 143-15-7 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromododecane, and the molecular formula is C12H25Br, Name: 1-Bromododecane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Nicolaou, K. C.’s team published research in Journal of the American Chemical Society in 139 | CAS: 69361-41-7

Journal of the American Chemical Society published new progress about 69361-41-7. 69361-41-7 belongs to bromides-buliding-blocks, auxiliary class PROTAC Linker,Aliphatic Linker, name is (4-Bromobut-1-yn-1-yl)trimethylsilane, and the molecular formula is C7H13BrSi, Application of (4-Bromobut-1-yn-1-yl)trimethylsilane.

Nicolaou, K. C. published the artcile12,13-Aziridinyl Epothilones. Stereoselective Synthesis of Trisubstituted Olefinic Bonds from Methyl Ketones and Heteroaromatic Phosphonates and Design, Synthesis, and Biological Evaluation of Potent Antitumor Agents, Application of (4-Bromobut-1-yn-1-yl)trimethylsilane, the publication is Journal of the American Chemical Society (2017), 139(21), 7318-7334, database is CAplus and MEDLINE.

The synthesis and biol. evaluation of a series of 12,13-aziridinyl epothilone B analogs is described. These compounds were accessed by a practical, general process that involved a 12,13-olefinic Me ketone as a starting material obtained by ozonolytic cleavage of epothilone B followed by tungsten-induced deoxygenation of the epoxide moiety. The attachment of the aziridine structural motif was achieved by application of the Ess-Kurti-Falck aziridination, while the heterocyclic side chains were introduced via stereoselective phosphonate-based olefinations. In order to ensure high (E) selectivities for the latter reaction for electron-rich heterocycles, it became necessary to develop and apply an unprecedented modification of the venerable Horner-Wadsworth-Emmons reaction, employing 2-fluoroethoxyphosphonates that may prove to be of general value in organic synthesis. These studies resulted in the discovery of some of the most potent epothilones reported to date. Equipped with functional groups to accommodate modern drug delivery technologies, some of these compounds exhibited picomolar potencies that qualify them as payloads for antibody drug conjugates (ADCs), while a number of them revealed impressive activities against drug resistant human cancer cells, making them desirable for potential medical applications.

Journal of the American Chemical Society published new progress about 69361-41-7. 69361-41-7 belongs to bromides-buliding-blocks, auxiliary class PROTAC Linker,Aliphatic Linker, name is (4-Bromobut-1-yn-1-yl)trimethylsilane, and the molecular formula is C7H13BrSi, Application of (4-Bromobut-1-yn-1-yl)trimethylsilane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Frevel, L. K.’s team published research in Industrial and Engineering Chemistry, Analytical Edition in 18 | CAS: 594-81-0

Industrial and Engineering Chemistry, Analytical Edition published new progress about 594-81-0. 594-81-0 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 2,3-Dibromo-2,3-dimethylbutane, and the molecular formula is C6H12Br2, Formula: C6H12Br2.

Frevel, L. K. published the artcileTabulated diffraction data for tetragonal isomorphs, Formula: C6H12Br2, the publication is Industrial and Engineering Chemistry, Analytical Edition (1946), 83-93, database is CAplus.

cf. C.A. 32, 7841.8; 36, 2192.4; 37, 1671.9; 38, 32113. Continuing the valuable procedure for comparing diffraction patterns of isomorphic substances the authors present data for tetragonal isomorphs. Four complete figures depict representative diffraction patterns for 40 tetragonal substances, arranged in sets with the simplest structure with highest symmetry listed first. In addition 327 tetragonal substances, including 50 synthesized by the authors, are tabulated by types. The following table lists 447 in an ascending order of axial ratios: Na(0.2_0.4)WO3, γ-NH4I; Cd[Hg(CNS)4], NiSb2O4; Co[Hg(CNS)4], γ-NH4Br (∼173°K.); [CH3CHO]4, N(CH3)4Cl; Zn[Hg(CNS)4], N(CH3)4MnO4; Pt(NH3)4Cl2.H2O, N(CH3)4Br; Be-(W, Mo), C(CH2ONO2)4; Pd(NH3)4Cl2.H2O, Cl2 (88°K.); Ag(CH3.CS.NH2)4Cl, OsO5C4(CH3)8; MgPt(CN)4.7H2O, Ca(OCl)2.3H2O; Cu(CH3.CS.NH2)4Cl, N(CH3)4ClO4; [(CH3)3As, PdCl2]2, SnI b2O4; [(CH3)3As, PdBr2]2, N(CH3)4I; C(CH2OCOCH3)4, PH4I; CS2(∼100°K.), Cd3Hg; C6H4[1,2]CH3.SO2NH2, Na2(TiFe)Si4O11, narsarsukite; Fe3P, PbPb2O4; (Fe,Ni,Co)3P, Cu3Pd; Ni3P, Ag2SO4.4NH3; W4O11, Ca10Mg2Al4Si9O34(OH)4,; Cr3P, vesuvianite; Mn3P, C(COOCH3)4; KgMg(H2O)6(Cl,Br)3, LaAl4; NaK(Ca,Mg,Mn)Al4Si5O18.8H2O, ashcroftine, C2(CH3)4Br2 N(C2H5)4I; CdHg, TeO2; Pb(C6H5)4, PCl5; CH2OH(CHOH)2CH2OH, Al2Cu; (C6H4 [1,2]O.CH = NOH)2Pt, Sn2Fe; Sn(C6H5)4, Sn2Mn; β-Sn, 2-Hydroxy-10-methoxy-1,2,3,4,5,6,7,8,13,14,15-dodecahydrochrysene; [PNCl2]4, AgClO2, ZnHg(CNS)4, NiZn; WO2, Si[SC(CH3)3]4; MoO2, Ge[SC(CH3)3]4; K2PdCl4, Sn[SC(CH3)3]4; (C6H5)4AsI, Fe2B; K2PtCl4, (CH3)2CHSSi[SC(CH3)3]3; (NH4)2PdCl4, Co2B; Ge(C6H5)4, Ge2Fe; NH4ClO2, NaBaPO4; Na2Co(CNS)4.8H2O, julienite, KBaPO4; SeO2, Ni2B; Si(C6H5)4, Pb2Pd; [(CH3)2SiO]8, Sn2Co; CbO2, NaSrPO4; Ni4Mo, KSrPO4; Ca4Al6Si6O24(SO4,CO3), meionite, YVO4; Na4Al3Si9O24Cl, marialite, NH4NO3-II (357-398°K.); N(CH3)4ICl2, TlSe; RhVO4, CaCrO4; VO2, SrO2.8H2O; Ca2ZnSi2O7, hardystonite, Pb2Rh; RhCbO4, Ag3Ca; TiO2, YPO4; RhTaO4, ∼ZrH2; C(C6H5)4, ZrSiO4; CrO2, CuB2O4.CuCl2.4H2O, bandylite; CrCbO4, Sr(OH)2.8H2O; CrTaO4, YAsO4; GeO2, ∼MnBi2; FeTaO4, Hg(CN)2; (Ca,Na)2(Mg,Al)(Al2Si)2O7, PbIn2_3; melilite, AgClO3; MnO2, (Ca,Na)2Be(Si,Al)2(O,F)7,; FeSbO4, meliphanite; FeCbO4, AuCu; Ca2Al2SiO7, gehlenite, γ-Mn; AlSbO4, KH2AsO4; MgF2, 2Pb(OH)2.CuCl2, diaboleite; (Ca,Na)2Be(Al,Si)2(O,F)7, KH2PO4; meliphanite, AgBrO3; GaSbO4, W12O32(OH)2; NiF2, 95Mn.5Cu; CrSbO4, 96Mn.4Pd; ZnF2, 89Mn.11Cu; NH4SH, ∼70Mo-30N; SnO2, FePd; RhSbO4, NiMn; (Ca,Na)2BeSi2(O,OH,F)7, 62Mn.38N; leucophanite, AgSb(OH)6; MnF2, trans-Pd(NH3)2Cl; CoF2, 92Mn.8N; PbO2, Pd(NH3)2I2; NiAs2O4, 79Mn.21Cu; C(CH2OC6H5), NaSb(OH)6; PdF2, Ni4Mo; FeSb2O4, 66Mn.34Cu; MnSb2O4, Ag2HgI4; RuO2, NH4H2PO4; FeF2, NH4H2AsO4; CoSb2O4, BaTiO3; ZnSb2O4, SrPb3; IrO2, Cu2HgI4; MgSb2O4, ZrO2 (<1273° K.); OsO2, Pt(NH3)4PtCl4; Rb2CuCl4.2H2O, ZnMn2O4; (Pd, Pt, Ni)S, Mn2Sb ∼Ni2Sb, BaC2; PdS, C3H7NH3Br; CdIn2O4; Mg(ClO2)2.6H2O, Cr2Ni, Rb3CoCl5; (NH4)2CuCl4.2H2O, SrC2; ∼PbCl2.Cu(OH)2, cumengeite; (NH4)2CuBr4.2H2O, KAlSi2O5, leucite, MnMn2O4; α-Martensite, Fe2As; PbTiO3, NdC2; K2CuCl4.2H2O, CaC2; Al2C12O12.18H2O, mellite, BaFCl; In, PrC3; (NH4)2FeCl4.2H2O, CaO2; Pb2Cl2CO3, SmC2; Pb2Br2CO3, Mn2As; K3CrO8, CeC2; Cs3TaO8, LaC2; AgFO3, SrFCl; Rb3TaO8, l-Co(NH2.CH2.CH2.NH2)3Br3.H2O; K3TlCl5.2H2O, CsO2, 6CuO.Cu2O, paramelaconite; Rb3TlBr5.8/7H2O, BAFI; RbO2, NH4Pb2Br5; KNCO, CH3NH3Br; KN3, RbPb2Br5; K3CbO3, KAlF4; K3TaO3, RbAlF4; NiZn, KPb2Br5; RbN2, PdO; KO2, Cr2As; UC2, CH3NH3I; CH3NH3Cl, PtO; KFHF, PtS; PbO-Bi2O3, TlAlF4; Ca(UO2)2(PO4)2.61/2H2O, CaFCl; LiOH, PbFCl; K2OsO2Cl4, KCa4Si8O20F.8H2O, apophyllite; γ-LiBi, NH4AlF4; PbO, BaO2; Ca4NaAl3Si5O19, sarcolite, KUO2(CH3COO)3; SnO, α-Pt(NH3)2Cl4; ThC2, PbFBr; C2(CH3)2Br4, AgFeS2; Fe2(TeO3)3.xH2O, mackayite, NH4CN; Sr(OH)2.8H2O, (C2H5)3As.AgI; γ-Mn, SrO2; Ni-N, BiOCl; AuCu, NH4HgCl3; C4H4S (∼ 100°K.), thiophene, FeSi2; 5PbCrO4.3PbMoO4.10PbSO4, NiTa2O6; 95Mn.5Cu, Fe(Cb,Ta)2O6, mossite; MgIn, CoTa2O6; (Ca,Na)2BeSi2(O,OH,F)7, MgTa2O6; leucophanite, FeTa2O6, tapiolite; 89Mn.11Cu, Pb(Cl,OH)24PbO.2Fe2O3,; Ba(CH2COO)2, hämatophanite; NiMn, KHC2; FePd, CuFeS2, chalcopyrite; 79Mn.21Cu, Cu2FeSnS4, stannite; NaBi, KUO2(CH3COO)3; SiO2, H2O2; Cd3P2, 3Mn2O3.MnSiO3, braunite; 66Mn.34Cu, NH4UO2(CH3COO)3; AlPO4, Pb5Cu4Cl10O4.6H2O,; Li2O2, pseudoboleite; Ni2Sb4, ∼CuGa2; Zn3P2, TiGa3; Zn3As2, BiOBr; C d3As2, (Bi,W)8-nO12, russellite; [N(CH3)4]2SiF6, NaHC2; B2O3.24WO3.66H2O, BaFeSi4O10, gillespite; H4SiW12O40.31H2O, NH4IO4; C(CH2OH)4, AgUO2(CH3COO)3.xH2O; (NH4)5BW12O40.26H2O, CdMoO4; Cs2AuAuCl6, CaWO4; CuCl.3SC(NH2)2, NaLa(WO4)2; TiGa3, NaCe(WO4)2; Y(Cb, Ta)O4, Pr2(MoO4)3; YCbO4, LiLa(WO4)2; FeSe, CaMoO4; YTaO4, NaBi(MoO4)2; CuFe2O4, Nd2(MoO4)3; Na5Al3F14, NaReO4; Na2O2, VAl3; Cs2AgAuCl6, ZrGa3; AgCo(NH3)2(NO2)4, LiBi(MoO4)2; Pb(ClO2)2, LiLa(MoO4)2; C3H7NH3I, NaLa(MoO4)2; In, SrWO4; BAsO4, KIO4; Cu2Sb, RbIO4; BPO4, NH4ReO4; ZrGa3, Ce2(MoO4)3; VAl3, La2(MoO4)3; [N(CH3)2(C2H5)2]2SnCl6, PbWO4; ∼Fe3Ti, KLa(WO4)2; TaAl3, KBi(MoO4)2; C8H7NH3Cl, KCe(WO4)2; TiAl3, KReO4; CbAl3, TaAl3; CaIn2O4, Sn2(MoO4)3; Cs3CoCl5, AgReO4; SrMoO4, Cu(UO2)2(PO4)2.8H2O, torberite; PbMoO4, Ca(UO2)2(PO4)2.101/2H2O; KLa(MoO4)2, C4H9NH3I; TiAl3, C4H9NH3Cl; CbAl3, Hg2F2; NaIO4, C2H4(NH2)2.H2SO4; AgIO4, C4H9NH3Br; BaWO4, Tl(CH3)2Br; RbReO4, LiBi3O4Cl2; BiOI, NaBi3O4Cl2; BaMoO4, MnSi2; BiAsO4, NaBi3O4Br2; β-TlReO4 (400°K.), Cd2Bi2O4Br2; KOsO3N, LiBi3O4Br2; Hg2I2, Tl(CH3)2Cl; KCrO3F, C5H11NH3Cl; C28H36N4, acetonylpyrrol, Cd2Bi2O4I2; Hg2Br2, NaBi3O4I2; cis-[Pt(NH3)(C2H4)Cl2]2, LiBi3O4I2; 6Pb(S,Tl)2.AuTl2, nagyagite, C5H11NH3I; Hg2Cl2, C5H11NH3Br; WSi2, ThSi2; MoSi2, ZnP2; Al4Ba, CdP2; (CH2CO)2NI, C6H13NH3I; Al4Sr, La2MoO6; TiO2, C6H13NH3Cl; CsSO3F, C6H13NH3Br; CsCrO3F, Pb9Cu8Ag3Cl21O8.9H2O, boleite; Al4Ca, C7H15NH3I; CaNa4Al12(PO4)8(OH)18.6H2O wardite, C7H15NH3Cl ZrAl3; C5H4O4N4, l-spiro-5,5′-dihydantoin, C8H17NH3I β-Me d-glucoside; [(NH2)2CNH]2.H2CO3, C10H21NH3I; Tl(CH3)2I, Beyerite; 2,4,6(C6H2)I(NO2)3, C11H23NH3I; C6H4[1,2](COC2H5)2, C12H25NH3I; HgI2, C14H6O2[2,7](NO2)2, 2,7-dinitroanthraquinone; Cr2Al; The general procedure for identifying a noncatalogued pattern is: (1) plot the log d values and corresponding relative intensities of the unidentified pattern on a narrow strip of paper; (2) verify that the pattern is noncubic; (3) find an isomorphic prototype among the representative diffraction patterns; (4) compute lattice constants and check the appropriate classification tables; (5) confirm identification of the unknown by qual. spectroscopic anal., or by spot tests.

Industrial and Engineering Chemistry, Analytical Edition published new progress about 594-81-0. 594-81-0 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 2,3-Dibromo-2,3-dimethylbutane, and the molecular formula is C6H12Br2, Formula: C6H12Br2.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Seth, Punit P.’s team published research in Tetrahedron Letters in 43 | CAS: 53484-26-7

Tetrahedron Letters published new progress about 53484-26-7. 53484-26-7 belongs to bromides-buliding-blocks, auxiliary class Bromide,Nitro Compound,Amine,Benzene, name is 4-Bromo-N-methyl-2-nitroaniline, and the molecular formula is C12H10O4S, Synthetic Route of 53484-26-7.

Seth, Punit P. published the artcileEfficient solution phase synthesis of 2-(N-acylamino)benzimidazoles, Synthetic Route of 53484-26-7, the publication is Tetrahedron Letters (2002), 43(41), 7303-7306, database is CAplus.

An efficient solution phase protocol for the synthesis of 2-(N-acylamino)benzimidazoles is reported. The 2-(N-acylamino)benzimidazole ring system was assembled using SNAr reactions, nitro group reduction, acylthiourea formation and cyclization with EDC. The acyl protected 2-aminobenzimidazole derivatives were obtained in high yield and purity without purification of intermediates or final products. This reaction sequence eliminates the use of highly toxic cyanogen bromide, a reagent commonly used to prepare the 2-aminobenzimidazole ring system.

Tetrahedron Letters published new progress about 53484-26-7. 53484-26-7 belongs to bromides-buliding-blocks, auxiliary class Bromide,Nitro Compound,Amine,Benzene, name is 4-Bromo-N-methyl-2-nitroaniline, and the molecular formula is C12H10O4S, Synthetic Route of 53484-26-7.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Lee, Yujin’s team published research in Angewandte Chemie, International Edition in 56 | CAS: 69361-41-7

Angewandte Chemie, International Edition published new progress about 69361-41-7. 69361-41-7 belongs to bromides-buliding-blocks, auxiliary class PROTAC Linker,Aliphatic Linker, name is (4-Bromobut-1-yn-1-yl)trimethylsilane, and the molecular formula is C7H13BrSi, Category: bromides-buliding-blocks.

Lee, Yujin published the artcileAn Asymmetric Pathway to Dendrobine by a Transition-Metal-Catalyzed Cascade Process, Category: bromides-buliding-blocks, the publication is Angewandte Chemie, International Edition (2017), 56(40), 12250-12254, database is CAplus and MEDLINE.

An asym. pathway to the caged tetracyclic pyrrolidine alkaloid, dendrobine (I), is reported. The successful synthetic strategy features a one-pot, sequential palladium-catalyzed enyne cycloisomerization and rhodium-catalyzed diene-assisted pyrrolidine formation by allylic CH activation. The developed transition-metal-catalyzed cascade process permits rapid access to the dendrobine core structure II and circumvents the handling of labile intermediates. An intramol. aldol condensation under carefully defined reaction conditions takes place with a concomitant detosylation, followed by reductive amine methylation, to afford a late-stage intermediate (previously identified by several prior dendrobine syntheses) in only 10 synthetic steps overall.

Angewandte Chemie, International Edition published new progress about 69361-41-7. 69361-41-7 belongs to bromides-buliding-blocks, auxiliary class PROTAC Linker,Aliphatic Linker, name is (4-Bromobut-1-yn-1-yl)trimethylsilane, and the molecular formula is C7H13BrSi, Category: bromides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Gunsalus, Robert P.’s team published research in Biochemistry in 17 | CAS: 55788-44-8

Biochemistry published new progress about 55788-44-8. 55788-44-8 belongs to bromides-buliding-blocks, auxiliary class Bromide,Salt,Aliphatic hydrocarbon chain,Aliphatic hydrocarbon chain, name is Sodium 3-bromopropane-1-sulfonate, and the molecular formula is C3H6BrNaO3S, Category: bromides-buliding-blocks.

Gunsalus, Robert P. published the artcilePreparation of coenzyme M analogs and their activity in the methyl coenzyme M reductase system of Methanobacterium thermoautotrophicum, Category: bromides-buliding-blocks, the publication is Biochemistry (1978), 17(12), 2374-7, database is CAplus and MEDLINE.

A number of 2-(methylthio)ethanesulfonate (Me-coenzyme M, I) analogs were synthesized and investigated as substrates for I reductase, an enzyme system found in extracts of M. thermoautotrophicum. Replacement of the Me moiety by an Et group yielded an analog which served as a precursor for C2H6 formation. Pr-coenzyme M, however, was not converted to C3H8. Analogs which contained addnl. methylene C atoms, such as 3-(methylthio)propanesulfonate or 4-(methylthio)butanesulfonate or analogs modified at the sulfide or sulfonate position, N-methyltaurine and 2-(methylthio)ethanol, were inactive. These analogs, in addition to a number of com. available compounds, also were tested for their ability to inhibit the reduction of I to CH4. Bromoethanesulfonate and chloroethanesulonate proved to be potent inhibitors of the reductase, resulting in 50% inhibition at 7.9 × 10-6 M and 7.5 × 10-5 M, resp. Analogs of coenzyme M which contained modifications to other regions were also evaluated and found to be weak inhibitors of CH4 biosynthesis.

Biochemistry published new progress about 55788-44-8. 55788-44-8 belongs to bromides-buliding-blocks, auxiliary class Bromide,Salt,Aliphatic hydrocarbon chain,Aliphatic hydrocarbon chain, name is Sodium 3-bromopropane-1-sulfonate, and the molecular formula is C3H6BrNaO3S, Category: bromides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Thongbamrer, Chopaka’s team published research in ChemBioChem in 23 | CAS: 143-15-7

ChemBioChem published new progress about 143-15-7. 143-15-7 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromododecane, and the molecular formula is C12H17NS2, Computed Properties of 143-15-7.

Thongbamrer, Chopaka published the artcileSerum Compatible Spermine-Based Cationic Lipids with Nonidentical Hydrocarbon Tails Mediate High Transfection Efficiency, Computed Properties of 143-15-7, the publication is ChemBioChem (2022), 23(6), e202100672, database is CAplus and MEDLINE.

Cationic lipids are widely used as nonviral synthetic vectors for gene delivery as a safer alternative to viral vectors. In this work, a library of L-shaped spermine-based cationic lipids with identical and nonidentical hydrophobic chains having variable carbon lengths (from C10 to C18) was designed and synthesized. These lipids were characterized and the structure-activity relationships of these compounds were determined for DNA binding and transfection ability when formulated as cationic liposomes. The liposomes were then used successfully for the transfection of HEK293T, HeLa, PC3, H460, HepG2, SH-SY5Y and Calu′3 cell lines. The transfection efficiency of lipids with nonidentical hydrocarbon chains was greater than the identical analog. These reagents exhibited superior efficiency to the com. reagent, Lipofectamine3000, under both serum-free and 10-40 % serum conditions in HEK293T, HeLa and H460 cell lines. The lipids were not toxic to the tested cell line. The results suggest that L-shaped spermine-based cationic lipids with nonidentical hydrocarbon tails could serve as efficient and safe nonviral vector gene carriers in further in vivo studies.

ChemBioChem published new progress about 143-15-7. 143-15-7 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromododecane, and the molecular formula is C12H17NS2, Computed Properties of 143-15-7.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary