Tag: M.W=150-200

Vinyl bromides undergo the Heck reaction, which involves C-C coupling with alkene to give substituted alkenes. 629-04-9, formula is C7H15Br, Name is 1-Bromoheptane. Methyl bromide is a precursor in the manufacture of several chemicals and is employed as a soil sterilant, mainly for seed production. HPLC of Formula: 629-04-9.

Ali, Zinah Hussein;Jber, Nasreen Raheem research published 《 Supramolecular discotic mesophases containing melamine-core induced by hydrogen-bonding: synthesis and characterization》, the research content is summarized as follows. The purpose of the presented research is to develop suitable hydrogen-bonding complimentary chems. to produce melamine-core supra-mol. discotic liquid crystal (LC) materials that can be employed in various applications. Authors designed and synthesized 3,5-di-(3,4′,5′-trialkoxybenzoyloxy)benzoic acid derivatives, I (R = n-hexyl, n-heptyl, and n-octyl), one of three types of long-alkyloxytailed compounds with unique hydrogen-bonding matching functional groups. The liquid crystalline characteristics were assessed using polarized optical microscopy and DSC. Smectic and nematic phases were discovered.

HPLC of Formula: 629-04-9, 1-Bromoheptane is a useful research compound. Its molecular formula is C7H15Br and its molecular weight is 179.1 g/mol. The purity is usually 95%.
1-Bromoheptane is a reagent that is used for the preparation of alkylthiophienylzinc chloride.
1-Bromoheptane is a reactive compound that is used in the preparation of p-hydroxybenzoic acid, which is an intermediate in the synthesis of many natural compounds. 1-Bromoheptane has been shown to have biological properties and to inhibit mitochondrial membrane potential. It also causes cell lysis and hepatic steatosis in mice. This compound has been shown to inhibit the activity of enzymes such as acetylcholinesterase, butyrylcholinesterase, and carboxylesterase. 1-Bromoheptane can be used as a model for studying the effects on congestive heart failure by increasing cardiac workloads or decreasing myocardial contractility., 629-04-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 70-23-5, formula is C5H7BrO3, Name is Ethyl 3-bromo-2-oxopropanoate. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Name: Ethyl 3-bromo-2-oxopropanoate.

Alvarez, Natalia;Velluti, Francesca;Guidali, Florencia;Serra, Gloria;Gabriela Kramer, M.;Ellena, Javier;Facchin, Gianella;Scarone, Laura;Torre, Maria H. research published 《 New BI and TRI-Thiazole copper (II) complexes in the search of new cytotoxic drugs against breast cancer cells》, the research content is summarized as follows. New thiazolyl derivatives (BT and TT) and their copper (II) complexes [Cu₂Cl₂(BT)₂] (Cu-BT) and [Cu₄ClO₂(TT)₂]PF₆·3.5H₂O (Cu-TT) were synthesized and characterized by elemental anal., ¹H NMR and ¹³C NMR, HRMS, X-ray diffraction, IR and UV-Vis spectroscopies. The crystal structure of Cu-BT shows the formation of a dinuclear complex where each copper(II) center is bonded to two thiazol N atoms, from different BT ligands, one deprotonated amide N atom, an O atom from the ester terminal groups and a chlorine atom. The structure found for Cu-TT is a pos. charged tetranuclear moiety containing two deprotonated TT ligands, a chlorine anion, two hydroxide anions acting as bridges between the copper centers and a water mol. The cytotoxic activity of both copper complexes was evaluated on metastatic breast cancer cell lines, characterized for its rapidly dividing behavior. Both, Cu-BT and Cu-TT, show higher cytotoxic activity against these tumor cells than free BT and TT and also than cisplatin. In addition, we found that both complexes interact with DNA. Consistently, they also show cytotoxicity against a rapidly dividing non-tumor cell line, although with higher IC_50, being such interaction and selectivity an indicator of the possible coexistence of more than one mechanism of action.

70-23-5, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., Name: Ethyl 3-bromo-2-oxopropanoate

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 4224-70-8, formula is C6H11BrO2, Name is 6-Bromohexanoic acid. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Reference of 4224-70-8.

Alves Avelar, Leandro A.;Schrenk, Christian;Soennichsen, Melf;Hamacher, Alexandra;Hansen, Finn K.;Schliehe-Diecks, Julian;Borkhardt, Arndt;Bhatia, Sanil;Kassack, Matthias U.;Kurz, Thomas research published 《 Synergistic induction of apoptosis in resistant head and neck carcinoma and leukemia by alkoxyamide-based histone deacetylase inhibitors》, the research content is summarized as follows. Targeting epigenetic dysregulation has emerged as a valuable therapeutic strategy in cancer treatment. Especially epigenetic combination therapy of histone deacetylase inhibitors (HDACi) with established anti-cancer drugs has provided promising results in preclin. and clin. studies. The structural optimization of alkoxyamide-based class I/IIb inhibitors afforded improved analogs with potent efficacy in cisplatin-resistant head and neck carcinoma cells and bortezomib-resistant leukemia cells. The most promising HDACi showed a superior synergistic cytotoxic activity as compared to vorinostat and class I HDACi in combination with cisplatin, leading to a full reversal of the chemoresistant phenotype in head and neck cancer cell lines, as well in combination with the proteasome inhibitors (bortezomib and carfilzomib) in a panel of leukemic cell lines. Furthermore, the most valuable alkoxyamide-based HDACi exhibited strong ex vivo anticancer efficacy against primary patient samples obtained from different therapy-resistant leukemic entities.

Reference of 4224-70-8, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., 4224-70-8.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Dehydrobromination, Grignard reactions, reductive coupling, Wittig reaction, and several nucleophilic substitution reactions are some of the principal reactions which involve organic bromides. 70-23-5, formula is C5H7BrO3, Name is Ethyl 3-bromo-2-oxopropanoate. Organic compounds having carbon bonded to bromine are called organic bromides. Product Details of C5H7BrO3.

Alzain, Abdulrahim A.;Brisson, Lucie;Delaye, Pierre-Olivier;Penichon, Melanie;Chadet, Stephanie;Besson, Pierre;Chevalier, Stephan;Allouchi, Hassan;Mohamed, Magdi A.;Roger, Sebastien;Enguehard-Gueiffier, Cecile research published 《 Bioinspired imidazo[1,2-a:4,5-c’]dipyridines with dual antiproliferative and anti-migrative properties in human cancer cells: The SAR investigation》, the research content is summarized as follows. Design, synthesis and evaluation of novel bioinspired imidazo[1,2-a:4,5c’]dipyridines I [X = Br or I; R¹ = Me, Et, Ph, etc.; R² = c-Pr, t-Bu, Ph, etc.; R³ = H, Me, Br, etc.; R⁴ = H, Et, Bn]. The structural optimization identified four anti-proliferative compounds Compounds I [X = Br or I; R¹ = Me, MeO, R² = Ph, t-Bu, c-Pr, R³ = H, R⁴ = Bn] exhibited excellent anticancer activities in vitro with IC₅₀ of 0.4-5μM against three human cancer cell lines (MDA-MB-468, MDA-MB-435s and MDA-MB-231). These I [X = Br or I; R¹ = Me, MeO, R² = Ph, t-Bu, c-Pr, R³ = H, R⁴ = Bn] induced apoptosis in MDA-MB-231 cells in a dose-dependent manner, targeting different apoptotic proteins expression: I [R¹ = Me, R² = Ph, R³ = H, R⁴ = Bn] increased the expression of pro-apoptotic Bax protein while 18-20 reduced the level of anti-apoptotic Bcl-2 protein. Compounds I [X = Br; R¹ = MeO, R² = t-Bu, c-Pr, R³ = H, R⁴ = Bn] also reduced MDA-MB-231 cells proliferation as measured by Ki-67 staining. Furthermore, compounds were also tested for the ability to inhibit cell migration in the highly aggressive human MDA-MB-435s cell line. Six compounds of this series I [X = Br; R¹ = Me, Ph, MeO, HO, Et, R² = t-Bu, Ph, c-Pr, R³ = H, Br, R⁴ = Bn] inhibited cell migration by 41-50% while four compounds I [X = Br; R¹ = MeO, Ph, R² = Ph, t-Bu, R³ = H, Br, Ph, 1-benzyl pyridinium-4-yl, R⁴ = Bn, H] inhibited the migration by 53-62% in wound-healing experiments Interestingly, compound I [X = Br, R¹ = OMe, R² = Ph, R³ = H, R⁴ = Bn]. presented both antiproliferative and anti-migration activities and were promising anti-metastatic agent for cancer treatment.

Product Details of C5H7BrO3, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., 70-23-5.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 1575-37-7, formula is C6H7BrN2, Name is 4-Bromobenzene-1,2-diamine. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Name: 4-Bromobenzene-1,2-diamine.

An, Xiaoying;Gao, Lei;Wang, Mingliang;Wu, Haitao;Wang, Lanzhi research published 《 One-pot synthesis of 1,5-benzodiazepine-2,3-dicarboxylates via three-component domino reactions in the presence of γ-Fe₂O₃@SiO₂/Ce(OTf)₃》, the research content is summarized as follows. Novel, efficient and environmentally friendly approaches was developed for the synthesis of 1,5-benzodiazepine-2,3-dicarboxylates I [R¹ = H, Me, Cl, Br; R² = Me, Et, Ph; R³ = Me, Et, Pr] and II by one-pot three-component domino reactions in the presence of a catalytic amount of γ-Fe₂O₃@SiO₂/Ce(OTf)₃ in EtOH at ambient temperature A total of synthesized 2,5-dihydro-1H-1,5-benzodiazepine-2,3-dicarboxylates I and 2-methyl-2,3-dihydro-1H-1,5-benzodiazepine-2,3-dicarboxylates II with enamine or imine structure of the heterocycle, resp., were obtained in good yields by reacting substituted 1,2-phenylenediamine, β-carbonyl esters and Et glyoxylate or Et pyruvate. One-pot reactions were successfully realized to form one new cycle and four new bonds (one C-C, two C-N, one C=C or two C-C, one C-N, one C=N). The salient features of this reaction included short reaction time, mild reaction conditions, moderate to excellent yields, recyclability of the catalyst, and wide substrate scope.

Name: 4-Bromobenzene-1,2-diamine, 4-Bromo-1,2-diaminobenzene can be obtained from 1,2-diaminobenzene via acetylation followed by bromination and alkaline hydrolysis.
4-Bromobenzene-1,2-diamine, also known as 4-Bromobenzene-1,2-diamine, is a useful research compound. Its molecular formula is C6H7BrN2 and its molecular weight is 187.04 g/mol. The purity is usually 95%.
4-Bromo-1,2-diaminobenzene is a dye that is used in diagnostic
procedures to detect the presence of amide groups. 4-Bromo-1,2-diaminobenzene can be used as an inhibitor for cationic polymerization reactions. It also has tuberculostatic activity and inhibits the growth of Mycobacterium tuberculosis. This compound reacts with aniline to form a benzimidazole derivative that contains a reactive amine group. The reaction between this amine group and different electrophiles generates benzimidazole compounds with different properties that are useful in nucleophilic attack reactions. The reaction between 4-bromo-1,2-diaminobenzene and methyl ethyl sulfide produces a luminescent probe that can be used to detect hydrogen bonds., 1575-37-7.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 1575-37-7, formula is C6H7BrN2, Name is 4-Bromobenzene-1,2-diamine. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Application of C6H7BrN2.

An, Xiaoying;Bai, Fan;Li, Wenhong;Wang, Lanzhi research published 《 Synthesis of 2,3-diester-2,4-diphenyl-1,5-benzodiazepine compounds via one-pot three-component tandem reactions》, the research content is summarized as follows. In this paper, seven novel 2,3-diester-2,4-diphenyl-1,5-benzodiazepines with imine structure were obtained via one-pot three-component tandem reactions catalyzed by TsOH in ethanol. With substituted 1,2-phenylenediamines, Et benzoylacetate and Et benzoylformate as the raw materials, the tandem reactions undergo two nucleophilic addition-dehydration processes to form the active intermediate mols. containing imine and enamine structures, further undergo carbon-carbon coupling cyclization and hydrogen transfer to yield the target products. A reasonable reaction mechanism is proposed for this three-component tandem reaction. The synthesis has the advantages of environmental friendliness, mild reaction conditions, wide substrate range, etc., which provides a green, efficient and convenient synthetic route for nitrogen-containing heterocyclic compounds

1575-37-7, 4-Bromo-1,2-diaminobenzene can be obtained from 1,2-diaminobenzene via acetylation followed by bromination and alkaline hydrolysis.
4-Bromobenzene-1,2-diamine, also known as 4-Bromobenzene-1,2-diamine, is a useful research compound. Its molecular formula is C6H7BrN2 and its molecular weight is 187.04 g/mol. The purity is usually 95%.
4-Bromo-1,2-diaminobenzene is a dye that is used in diagnostic
procedures to detect the presence of amide groups. 4-Bromo-1,2-diaminobenzene can be used as an inhibitor for cationic polymerization reactions. It also has tuberculostatic activity and inhibits the growth of Mycobacterium tuberculosis. This compound reacts with aniline to form a benzimidazole derivative that contains a reactive amine group. The reaction between this amine group and different electrophiles generates benzimidazole compounds with different properties that are useful in nucleophilic attack reactions. The reaction between 4-bromo-1,2-diaminobenzene and methyl ethyl sulfide produces a luminescent probe that can be used to detect hydrogen bonds., Application of C6H7BrN2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 1575-37-7, formula is C6H7BrN2, Name is 4-Bromobenzene-1,2-diamine. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Computed Properties of 1575-37-7.

Dusold, Carolin;Sharapa, Dmitry I.;Hampel, Frank;Hirsch, Andreas research published 《 π-Extended Diaza[7]helicenes by Hybridization of Naphthalene Diimides and Hexa-peri-hexabenzocoronenes》, the research content is summarized as follows. The synthesis of an unprecedented, π-extended hexabenzocorene (HBC)-based diaza[7]helicene I is presented. The target compound I was synthesized by an ortho-fusion of two naphthalene diimide (NDI) units to a HBC-skeleton. A combination of Diels-Alder and Scholl-type oxidation reactions involving a sym. di-NDI-tolane precursor II was crucial for the very selective formation of the helical superstructure via a hexaphenyl-benzene (HPB) derivative III. The formation of the diaza[7]helicene moiety I in the final Scholl oxidation is favored, affording the sym. π-extended helicene as the major product as a pair of enantiomers. The separation of the enantiomers was successfully accomplished by HPLC involving a chiral stationary phase. The absolute configuration of the enantiomers was assigned by comparison of CD spectra with quantum mech. calculations

Computed Properties of 1575-37-7, 4-Bromo-1,2-diaminobenzene can be obtained from 1,2-diaminobenzene via acetylation followed by bromination and alkaline hydrolysis.
4-Bromobenzene-1,2-diamine, also known as 4-Bromobenzene-1,2-diamine, is a useful research compound. Its molecular formula is C6H7BrN2 and its molecular weight is 187.04 g/mol. The purity is usually 95%.
4-Bromo-1,2-diaminobenzene is a dye that is used in diagnostic
procedures to detect the presence of amide groups. 4-Bromo-1,2-diaminobenzene can be used as an inhibitor for cationic polymerization reactions. It also has tuberculostatic activity and inhibits the growth of Mycobacterium tuberculosis. This compound reacts with aniline to form a benzimidazole derivative that contains a reactive amine group. The reaction between this amine group and different electrophiles generates benzimidazole compounds with different properties that are useful in nucleophilic attack reactions. The reaction between 4-bromo-1,2-diaminobenzene and methyl ethyl sulfide produces a luminescent probe that can be used to detect hydrogen bonds., 1575-37-7.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 70-23-5, formula is C5H7BrO3, Name is Ethyl 3-bromo-2-oxopropanoate, COA of Formula: C5H7BrO3

Ghazvini, Maryam;Sheikholeslami-Farahani, Fatemeh;Hamedani, Naghmeh Faal;Shahvelayati, Ashraf Sadat;Rostami, Zohreh research published 《 Bio-Fe₃O₄ Magnetic Nanoparticles Promoted Green Synthesis of thioxo-1,3-Oxazole Derivatives: Study of Antimicrobial and Antioxidant Activity》, the research content is summarized as follows. In this work, 1,3-oxazoles I (R = COOEt, 4-methoxyphenyl, 4-methylphenyl, 4-bromophenyl; R¹ = t-Bu, 4-methoxyphenyl, 4-nitrophenyl; R² = COOEt, 4-methoxyphenyl, 4-methylphenyl, 4-bromophenyl) were generated using the multicomponent reaction of α-bromo ketones R/R²C(O)CH₂Br, alkyl (aryl) isothiocyanates R¹N=C=S, sodium hydride and Fe₃O₄ MNPs in the water at room temperature in good yields. The nanoparticles generated via the biosynthesis method have potential value in different purposes, such as organic synthesis. To study the antioxidant ability of some synthesized thioxo-1,3-oxazoles I, diphenyl-picrylhydrazine (DPPH) radical trapping and power of ferric reduction testes are employed. Among the studied thioxo-1,3-oxazoles, compound I (R = R² = COOEt; R¹ = 4-nitrophenyl) have good power for radical trapping and reduction activity than the standard antioxidants such as BHT and TBHQ. In addition, the antimicrobial activity of some thioxo-1,3-oxazoles I was studied, employing the disk diffusion test on Gram-pos. bacteria and Gram-neg. bacteria. The results of the disk diffusion test showed that compounds I (R = R² = COOEt, R¹ = 4-nitrophenyl; R = R² = COOEt, R¹ = 4-methoxyphenyl; R = R² = 4-methoxyphenyl, R¹ = t-Bu; R = R² = 4-bromophenyl R¹ = 4-nitrophenyl) prevented bacterial growth. Without employing catalyst, these reactions have low yield and busy mixture The synthesis of compound I (R = R² = COOEt; R¹ = 4-methoxyphenyl) as sample reaction has a similar yield in the presence of ZnO-NPs and Fe₃O₄ MNPs (entry 20 and entry 30), but the removal of catalyst from the mixture of reaction after the completion of the reaction is comfortable in the presence of Fe₃O₄ MNPs. Some of the advantages of performing these reactions with the present procedure are to carry out these reactions in water as a green solvent and simple removal of catalyst.

COA of Formula: C5H7BrO3, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., 70-23-5.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 5445-17-0, formula is C4H7BrO2, Name is Methyl 2-bromopropanoate. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Computed Properties of 5445-17-0.

Li, Xiaopei;Kato, Tatsuhisa;Nakamura, Yasuyuki;Yamago, Shigeru research published 《 The Effect of Viscosity on the Coupling and Hydrogen-Abstraction Reaction between Transient and Persistent Radicals》, the research content is summarized as follows. The effect of viscosity on the radical termination reaction between a transient radical and a persistent radical undergoing a coupling reaction (Coup) or hydrogen abstraction (Abst) was examined In a non-viscous solvent, such as benzene (bulk viscosity ηbulk < 1 mPa s), all the transient radicals studied exclusively coupled with 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) with >99% Coup/Abst selectivity, but Coup/Abst decreased as the viscosity increased (89/11 in PEG400 at 25°C [ηbulk = 84 mPa s]). While bulk viscosity is a good parameter to predict the Coup/Abst selectivity in each solvent, microviscosity is the more general parameter. Poly(Me methacrylate) (PMMA)-end radicals had a more significant viscosity effect than polystyrene (PSt)-end radicals, and the Coup/Abst ratio of the former dropped to 50/50 in highly viscous media (ηbulk = 3980 mPa s), while the latter maintained high Coup/Abst selectivity (84/16). These results, together with the low thermal stability of dormant PMMA-TEMPO species compared with that of PSt-TEMPO species, are attributed to the limitation of the nitroxide-mediated radical polymerization of MMA. While both organotellurium and bromine compounds were used as precursors of radicals, the former was superior to the latter for the clean generation of radical species. The effect of viscosity on the radical termination reaction between a transient radical and a persistent radical undergoing a coupling reaction (Coup) or hydrogen abstraction (Abst) was examined In a non-viscous solvent, such as benzene (bulk viscosity ηbulk < 1 mPa s), all the transient radicals studied exclusively coupled with 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) with >99% Coup/Abst selectivity, but Coup/Abst decreased as the viscosity increased (89/11 in PEG400 at 25°C [ηbulk = 84 mPa s]). While bulk viscosity is a good parameter to predict the Coup/Abst selectivity in each solvent, microviscosity is the more general parameter. Poly(Me methacrylate) (PMMA)-end radicals had a more significant viscosity effect than polystyrene (PSt)-end radicals, and the Coup/Abst ratio of the former dropped to 50/50 in highly viscous media (ηbulk = 3980 mPa s), while the latter maintained high Coup/Abst selectivity (84/16). These results, together with the low thermal stability of dormant PMMA-TEMPO species compared with that of PSt-TEMPO species, are attributed to the limitation of the nitroxide-mediated radical polymerization of MMA. While both organotellurium and bromine compounds were used as precursors of radicals, the former was superior to the latter for the clean generation of radical species.

5445-17-0, Methyl 2-bromopropionate, also known as Methyl 2-bromopropionate, is a useful research compound. Its molecular formula is C4H7BrO2 and its molecular weight is 167 g/mol. The purity is usually 95%.
Methyl 2-bromopropionate is used in the synthesis of poly(ADP-Ribose)polymerase inhibitors derived from benzoxazin-3-one. Also used in the synthesis of 5-HT2C antagonists affecting serotonin levels.
Methyl 2-bromopropanoate is a chemical compound that can be synthesized in an asymmetric manner. The reaction of methyl 2-bromopropanoate with hydrochloric acid gives the corresponding carboxylic acid, methyl propanoate, and hydrogen bromide in a 1:1 ratio. It has been shown that methyl 2-bromopropanoate is a potential catalyst for the reduction of chloride to chloride ion via the borohydride reduction method. Methyl 2-bromopropanoate has also been used as a model system for studying halides and copper complexes. Magnetic resonance spectroscopy studies have revealed that this chemical compound has a high redox potential and kinetic properties., Computed Properties of 5445-17-0

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 629-04-9, formula is C7H15Br, Name is 1-Bromoheptane. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Category: bromides-buliding-blocks.

Nakum, Kiran J.;Katariya, Kanubhai D.;Hagar, Mohamed;Jadeja, Rajendrasinh N. research published 《 The influence of lateral hydroxyl group and molecular flexibility on the mesogenic behavior of a new homologous series based on thiophene-chalcone: Synthesis, characterization, crystal structure and DFT study》, the research content is summarized as follows. A new homologous series of rod shaped calamite liquid crystals, I [R = Et, decyl, octadecyl, etc.] based on thiophene-chalcone was prepared by condensation of 2-hydroxy-4-n-alkoxybenzaldehydes (n = 2 to 8, 10, 12, 14, 16, 18) with (E)-1-(4-aminophenyl)-3-(thiophen-2-yl)prop-2-en-1-one. FT-IR, ¹H NMR, ¹³C NMR and mass spectroscopy were used to characterize synthesized compds I. The liquid crystal behavior of all synthetic compounds I was investigated using Differential Scanning Calorimeter (DSC) and Polarizing Optical Microscope (POM). Lower members of the homologous series, n-heptyloxy to n-dodecyloxy , were nematogenic, and higher members, n-tetradecyloxy to n-octadecyloxy , were smectogenic, whereas n-ethoxy to n-pentyloxy derivatives were non-mesogenic, and n-hexyloxy exhibited monotropic nematic phase. The n-pentyloxy derivative crystallized under monoclinic, space group P2/c with unit cell dimensions a = 16.1723(9) Å, b = 5.8603(3) Å, c = 22.4320(12) Å, β = 100.153(2) , V = 2092.69(9) Å3. The ethoxy derivative was subjected to DFT (d. functional theory) level computations and complete geometric optimization utilizing B3LYP/6-311G (d, p) basis sets and results were compared with structurally similar compound

Category: bromides-buliding-blocks, 1-Bromoheptane is a useful research compound. Its molecular formula is C7H15Br and its molecular weight is 179.1 g/mol. The purity is usually 95%.
1-Bromoheptane is a reagent that is used for the preparation of alkylthiophienylzinc chloride.
1-Bromoheptane is a reactive compound that is used in the preparation of p-hydroxybenzoic acid, which is an intermediate in the synthesis of many natural compounds. 1-Bromoheptane has been shown to have biological properties and to inhibit mitochondrial membrane potential. It also causes cell lysis and hepatic steatosis in mice. This compound has been shown to inhibit the activity of enzymes such as acetylcholinesterase, butyrylcholinesterase, and carboxylesterase. 1-Bromoheptane can be used as a model for studying the effects on congestive heart failure by increasing cardiac workloads or decreasing myocardial contractility., 629-04-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary