Tag: 300-400

Effects of structural modification of (alkyldiene-imidazolium bromide)-based gemini monomers on the formation of the lyotropic bicontinuous cubic phase was written by Li, Patrick;Reinhardt, Maria I.;Dyer, Samantha S.;Moore, Kara E.;Imran, Omar Q.;Gin, Douglas L.. And the article was included in Soft Matter in 2021.Product Details of 56523-59-2 This article mentions the following:

Seven homologues of an amphiphilic gemini monomer were synthesized and screened for the ability to form a bicontinuous cubic (Q) lyotropic liquid crystal phase. Four of these homologues form a Q phase with glycerol or water that can be cross-linked with retention of the nanoporous structure, with one exhibiting a well-ordered Q phase with a wider phase window than the parent monomer. In the experiment, the researchers used many compounds, for example, 15-Bromopentadecanoic acid (cas: 56523-59-2Product Details of 56523-59-2).

15-Bromopentadecanoic acid (cas: 56523-59-2) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.Product Details of 56523-59-2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

X-ray structure and ligand binding study of a moth chemosensory protein was written by Lartigue, Audrey;Campanacci, Valerie;Roussel, Alain;Larsson, Anna M.;Jones, T. Alwyn;Tegoni, Mariella;Cambillau, Christian. And the article was included in Journal of Biological Chemistry in 2002.SDS of cas: 56523-59-2 This article mentions the following:

Chemosensory proteins (CSPs) are believed to be involved in chem. communication and perception. Such proteins, of M_r 13,000, have been isolated from several sensory organs of a wide range of insect species. Several CSPs have been identified in the antennae and proboscis of the moth Mamestra brassicae. One of them, CSPMbraA6, a 112-amino acid antennal protein, has been expressed in large quantities and is soluble in the Escherichia coli periplasm. X-ray structure determination has been performed in parallel with ligand binding assays using tryptophan fluorescence quenching. The protein has overall dimensions of 25 × 30 × 32 Å and exhibits a novel type of α-helical fold with six helixes connected by α-α loops. A narrow channel extends within the protein hydrophobic core. Fluorescence quenching with brominated alkyl alcs. or fatty acids and modeling studies indicates that CSPMbraA6 is able to bind such compounds with C12-18 alkyl chains. These ubiquitous proteins might have the role of extracting hydrophobic linear compounds (pheromones, odors, or fatty acids) dispersed in the phospholipid membrane and transporting them to their receptor. In the experiment, the researchers used many compounds, for example, 15-Bromopentadecanoic acid (cas: 56523-59-2SDS of cas: 56523-59-2).

15-Bromopentadecanoic acid (cas: 56523-59-2) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.SDS of cas: 56523-59-2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Preparation of substituted triphenylenes via nickel-mediated Yamamoto coupling was written by Schroeder, Zachary W.;LeDrew, Joshua;Selmani, Vanessa M.;Maly, Kenneth E.. And the article was included in RSC Advances in 2021.Name: Dimethyl 4,5-dibromophthalate This article mentions the following:

It was demonstrated that the nickel-mediated Yamamoto coupling of o-dibromoarenes is a concise and efficient way to prepare substituted triphenylenes, including electron-deficient systems that are otherwise challenging to prepare The application of this approach to prepare electron deficient discotic mesogens composed of triphenylenes bearing imide and thioimide groups were also demonstrated. In the experiment, the researchers used many compounds, for example, Dimethyl 4,5-dibromophthalate (cas: 859299-66-4Name: Dimethyl 4,5-dibromophthalate).

Dimethyl 4,5-dibromophthalate (cas: 859299-66-4) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.Name: Dimethyl 4,5-dibromophthalate

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Formation of macrocyclic lactones in microemulsions was written by Gonzalez, Alvaro;Holt, Smith L.. And the article was included in Journal of Organic Chemistry in 1981.Quality Control of 15-Bromopentadecanoic acid This article mentions the following:

Macrocyclic lactones were prepared by using the reactants in detergentless microemulsions. A microemulsion of H₂O, Me₂CHOH, and PhMe was made 8 × 10^-3M in 4-MeC₆H₄SO₃H and treated with an identical microemulsion 1 × 10^-2M in Me(CH₂)₅CH(OH)(CH₂)₁₀CO₂H, HO(CH₂)₁₄CO₂H, or HO(CH₂)₁₅CO₂H over 2 h and the mixture heated at 65° 12 h to give 18-23% lactones I (R = benzyl, n = 10; R = H, n = 14, 15), 35-40% the iso-Pr esters, and 20% polymers. The above microemulsion was made 3 × 10^-3M in Br(CH₂)_mCO₂H (m = 10, 14) and an equivalent KOH added to form the K salt. This solution was heated at 65° 1 day to give 25 and 22% I (R = H, n = 9, 13) and 18 and 15% polymers. In the experiment, the researchers used many compounds, for example, 15-Bromopentadecanoic acid (cas: 56523-59-2Quality Control of 15-Bromopentadecanoic acid).

15-Bromopentadecanoic acid (cas: 56523-59-2) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine.Quality Control of 15-Bromopentadecanoic acid

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Robust Maleimide-Functionalized Gold Surfaces and Nanoparticles Generated Using Custom-Designed Bidentate Adsorbates was written by Park, Chul Soon;Lee, Han Ju;Jamison, Andrew C.;Lee, T. Randall. And the article was included in Langmuir in 2016.Formula: C15H29BrO2 This article mentions the following:

A series of custom-designed alkanethioacetate ligands were synthesized to provide a facile method of attaching maleimide-terminated adsorbates to gold nanostructures via thiolate bonds. Monolayers on flat gold substrates derived from both mono- and dithioacetates, with and without oligo(ethylene glycol) (OEG) moieties in their alkyl spacers, were characterized using XPS, polarization modulation IR reflection-absorption spectroscopy, ellipsometry, and contact angle goniometry. For all adsorbates, the resulting monolayers revealed that a higher packing d. and more homogeneous surface were generated when the film was formed in EtOH, but a higher percentage of bound thiolate was obtained in THF. A series of gold nanoparticles (AuNPs) capped with each adsorbate were prepared to explore how adsorbate structure influences aqueous colloidal stability under extreme conditions, as examined visually and spectroscopically. The AuNPs coated with adsorbates that include OEG moieties exhibited enhanced stability under high salt concentration, and AuNPs capped with dithioacetate adsorbates exhibited improved stability against ligand exchange in competition with dithiothreitol (DTT). Overall, the best results were obtained with a chelating dithioacetate adsorbate that included OEG moieties in its alkyl spacer, imparting improved stability via enhanced solubility in water and superior adsorbate attachment owing to the chelate effect. In the experiment, the researchers used many compounds, for example, 15-Bromopentadecanoic acid (cas: 56523-59-2Formula: C15H29BrO2).

15-Bromopentadecanoic acid (cas: 56523-59-2) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Formula: C15H29BrO2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

4,8,9-Tribromofluoranthene was written by Campbell, Neil;Leadill, W. K.;Wilshire, J. F. K.. And the article was included in Journal of the Chemical Society in 1952.Synthetic Route of C10H8Br2O4 This article mentions the following:

The tribromofluoranthene obtained by bromination of fluoranthene is the 4,8,9-isomer (C.A. numbering). Thus to 10 g. 4,9-dibromofluoranthene, 6.8 g. AcBr, and 50 mL. CS₂ stirred at 0° was added 11.0 g. AlCl₃, the mixture poured after 72 h. at room temperature into cold concentrated HCl, and the CS₂ removed on a steam bath, yielding 10 g. crude product, m. 130-45°. Chromatog. separation gave 8-acetyl-4,9-dibromofluoranthene (I), yellow prisms, m. 159-62°. I added to a solution prepared from Br and 3N NaOH at 0°, the mixture stirred 22 h. at 60°, filtered, and the residue washed, dried, and boiled with C₆H₆, then with concentrated HCl, yielded 4,9-dibromo-8-fluoranthenecarboxylic acid (II), m. 306-8°; Me ester, m. 190-1°. II boiled with 10% alc. KOH and Ni-Al alloy yielded 8-fluoranthene carboxylic acid, m. 284-7°; Me ester m. 93-4°. I with NaN₃ gave 8-acetamido-4,9-dibromofluoranthene, m. 284-8°; addition of HBr gave 8-amino-4,9-dibromofluoranthene-HBr, m. 245-6°, which with aqueous NH₃ yielded the amine (III), m. 256-8°. III boiled with AcOH, cooled, poured into NaNO₂ in H₂SO₄, and the solution added to CuBr solution in HBr yielded 4,8,9-tribromofluoranthene (IV), m. 208-10.5°. Oxidation of IV with Na₂Cr₂O₇ under various conditions gave 4,5,1,2-Br₂C₆H₂(CO₂H)₂, m. 200-1° (di-Me ester, m. 78-9°); 6,7-dibromo-, m. 277-9°, and 2,6,7-tribromo-9-oxo-1-fluorenecarboxylic acid, m. 317-20°. In the experiment, the researchers used many compounds, for example, Dimethyl 4,5-dibromophthalate (cas: 859299-66-4Synthetic Route of C10H8Br2O4).

Dimethyl 4,5-dibromophthalate (cas: 859299-66-4) belongs to organobromine compounds. Many of the organo bromine compounds are relatively nonpolar. Bromine is more electronegative than carbon (2.8 vs 2.5) and hence the carbon in a carbon–bromine bond is electrophilic in nature. Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.Synthetic Route of C10H8Br2O4

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Synthesis of some derivatives of juniperic acid was written by Plesek, Jaromir. And the article was included in Chemicke Listy pro Vedu a Prumysl in 1956.HPLC of Formula: 56523-59-2 This article mentions the following:

ω-Bromopalmitic acid (I), obtained in a 3-g. yield by saturating an Et₂O solution of 3 g. 1-pentadecene-15-carboxylic acid with HBr in the presence of 0.02 g. Bz₂O₂. crystals from ligroine, m. 70-1°. A solution of 2.5 g. I in 100 mL. MeCOEt (II) was dropped during 30 h. into 1000 mL. boiling II containing 20 g. dry K₂CO₃ and the mixture refluxed 8 h. After evaporating II, the residue was dissolved in 30 mL. ligroine, the insoluble K salts and a dilactone were filtered off and the filtrate was distilled, yielding 1.5 g. crystalline 1,16-hexadecanolide (III), b_0.5 124°, m. 18°, besides 10 g. of a forerun, b_0.5 100°, consisting of a condensation product of II. Saponification of III by boiling 40% aqueous NaOH gave juniperic acid, m. 94-5° (from C₆H₆) in a 98% yield. 1-Bromopentadecan-11-one-15-carboxylic acid (IV) was prepared by the Grignard reaction from 21 g. Et cyclopentanonecarboxylate and 26.5 g. ω-bromoundecyl chloride. The reaction product was boiled with AcOH and aqueous HBr and poured into water, yielding 20 g. IV, m. 77-8° (from C₆H₆-ligroine), obtained more easily in an 80%-yield by addition of HBr to 1-pentadecen-11-one-15-carboxylic acid in the presence of Bz₂O₂. A solution of 13.5 g. IV in 570 mL. II was dropped during 48 h. into a boiling suspension of dry K₂CO₃ in 3000 mL. II and refluxed 16 h., yielding 9 g. 6-oxo-1,16-hexadecanolide (V), b_0.5 155°, m. 35°. Saponification of V by boiling with alc. KOH gave a 98% yield 6-oxojuniperic acid, m. 94-5° (from C₆H₆); semicarbazone, m. 147-8° (from EtOH). In the experiment, the researchers used many compounds, for example, 15-Bromopentadecanoic acid (cas: 56523-59-2HPLC of Formula: 56523-59-2).

15-Bromopentadecanoic acid (cas: 56523-59-2) belongs to organobromine compounds. Many of the organo bromine compounds are relatively nonpolar. Bromine is more electronegative than carbon (2.8 vs 2.5) and hence the carbon in a carbon–bromine bond is electrophilic in nature. One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine.HPLC of Formula: 56523-59-2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A simple method for the synthesis of exaltolide was written by Sato, Toshio;Kawara, Tatsuo;Kokubu, Yasuchika;Fujisawa, Tamotsu. And the article was included in Bulletin of the Chemical Society of Japan in 1981.Related Products of 56523-59-2 This article mentions the following:

Copper-catalyzed reaction of β-propiolactone with 12-methoxydodecylmagnesium bromide, derived from 1,12-dodecanediol, gave 99% 15-methoxypentadecanoic acid which was easily converted into exaltolide (I). In the experiment, the researchers used many compounds, for example, 15-Bromopentadecanoic acid (cas: 56523-59-2Related Products of 56523-59-2).

15-Bromopentadecanoic acid (cas: 56523-59-2) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.Related Products of 56523-59-2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Component analysis of 450 °C pyrolyzate from benzene/ethanol extractive of Camellia oleifera cakes was written by Mo, Wei;Zhang, Dang-quan;Li, Bi-xia;Gu, Zhen-jun;Chen, Rong;Ye, Xiao-fei;Peng, Kuan;Zhang, Xiao-lei. And the article was included in Zhongnan Linye Keji Daxue Xuebao in 2015.Synthetic Route of C15H29BrO2 This article mentions the following:

Camellia oleifera cake was firstly lyophilized and extracted by Soxhlet extraction method, the benzene/ethanol extractive was treated with a thermal cracking process in He-flow at 450°C, and then the thermal-cracking product was analyzed by online Py-GC/MS, the relative contents of each component were computed by adopting chromatog. peak area normalization method, a total of 30 compounds were identified. The anal. results show that the pyrolyzate of the benzene/ethanol extractives contains various kinds of precious biomedical, spicery ingredients and specific chems., which are of great potentialities for high-grade cosmetics and skin care products, as well as excellent materials for food, dye and solvent industries. The findings provide new developing directions for deep processing and utilization of Camellia oleifera cakes resources. In the experiment, the researchers used many compounds, for example, 15-Bromopentadecanoic acid (cas: 56523-59-2Synthetic Route of C15H29BrO2).

15-Bromopentadecanoic acid (cas: 56523-59-2) belongs to organobromine compounds. Many of the organo bromine compounds are relatively nonpolar. Bromine is more electronegative than carbon (2.8 vs 2.5) and hence the carbon in a carbon–bromine bond is electrophilic in nature. Many of the alkyl bromine derivatives are excellent alkylating agents since bromides are good leaving groups. Tribromides, like tetrabutylammonium tribromide, are used as a solid source of bromine. N-bromosuccimide (NBS) is used for the selective bromination of allylic bonds.Synthetic Route of C15H29BrO2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Hypolipidemic alkoxybenzoic acids was written by DeVries, Vern G.;Moran, Daniel B.;Allen, George R.;Riggi, Stephen J.. And the article was included in Journal of Medicinal Chemistry in 1976.SDS of cas: 56523-59-2 This article mentions the following:

A series of �0 p-alkoxybenzoic acids (I) with aromatic ring substituents or modified alkyl or unsaturated chains (R1), prepared by alkylation of the appropriate hydroxybenzoate ester followed by saponification, was screened in rats for serum-sterol and triglyceride lowering activity. Alkyl chain substituents such as chloro and oximino enhanced activity, while azido, thiol, and some alkylthio groups resulted in retention of activity. Some alkylthio substituents on the alkyl chain and aryl ring substituents abolished sterol-lowering activity. The effect of alkyl chain branching was variable, while unsaturation had no adverse effect on activity except when located near either end of the chain. In the experiment, the researchers used many compounds, for example, 15-Bromopentadecanoic acid (cas: 56523-59-2SDS of cas: 56523-59-2).

15-Bromopentadecanoic acid (cas: 56523-59-2) belongs to organobromine compounds. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.SDS of cas: 56523-59-2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary