Tag: 300-400

Preparation and Reactions of CF₃-Containing Phthalides was written by Mitobe, Kana;Terashima, Kyu;Kawasaki-Takasuka, Tomoko;Agou, Tomohiro;Kubota, Toshio;Yamazaki, Takashi. And the article was included in European Journal of Organic Chemistry in 2018.Formula: C10H8Br2O4 This article mentions the following:

We have demonstrated that reactions of aromatic 1,2-diesters and the Ruppert-Prakash reagent (TMSCF₃) afforded hitherto unknown phthalides with both trifluoromethyl (CF₃) and alkoxy groups at the 3 position. Their unique transformation was also investigated in detail to attain construction of a variety of very rare types of compounds, such as 1,3-dihydroisobenzofurans as well as indanones with a CF₃ moiety, whose behavior was completely different from the structurally similar hydroxy compound In the experiment, the researchers used many compounds, for example, Dimethyl 4,5-dibromophthalate (cas: 859299-66-4Formula: C10H8Br2O4).

Dimethyl 4,5-dibromophthalate (cas: 859299-66-4) belongs to organobromine compounds. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.Formula: C10H8Br2O4

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Analysis of low polar constituents of mangrove endophytic fungus 350# by GC-MS was written by Li, Shang-de;Wei, Mei-yan;Zheng, Ming-bin;Chen, Ming-xiang;Lin, Yong-cheng. And the article was included in Guangzhou Huagong in 2013.Name: 15-Bromopentadecanoic acid This article mentions the following:

Low polar constituents of mangrove endophytic fungus 350# were firstly reported by GC-MS anal. Twenty-nine kinds of compounds in mangrove endophytic fungus 350# were identified through a database, including hydrocarbons, alcs., aldehydes, ketones, carboxylic acid esters and amides. The data showed that the content of ketones reached up to 32.35%, followed by the amide (15.53%), paraffins (13.32%), aldehydes (12.02%), olefins (8.62%), carboxylate (5.62%) and alc. (3.59%). Quinone Ke Sam hormone and blue snow quinone with significant biol. activity were firstly identified from mangrove endophytic fungus 350#. The Quinone Ke Sam hormone content was 23.31% and blue snow quinone content was 2.97%. The research provided a new basis for the further development and utilization of red olive trees. In the experiment, the researchers used many compounds, for example, 15-Bromopentadecanoic acid (cas: 56523-59-2Name: 15-Bromopentadecanoic acid).

15-Bromopentadecanoic acid (cas: 56523-59-2) belongs to organobromine compounds. Many of the organo bromine compounds are relatively nonpolar. Bromine is more electronegative than carbon (2.8 vs 2.5) and hence the carbon in a carbon–bromine bond is electrophilic in nature. Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.Name: 15-Bromopentadecanoic acid

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Electroorganic chemistry. 91. A novel base useful for synthesis of esters and macrolides was written by Shono, Tatsuya;Ishige, Osamu;Uyama, Hiroshi;Kashimura, Shigenori. And the article was included in Journal of Organic Chemistry in 1986.Category: bromides-buliding-blocks This article mentions the following:

The anionic species (I) formed by the electroreduction of 2-pyrrolidone in DMF in the presence of tetraalkylammonium salts was a highly efficient base for the esterification of acids such as gibberellic and 6-aminopenicillanic acids which are not always stable under the usual esterification conditions. I was also useful for the selective transformation of ω-halo carboxylic acids to the corresponding macrolides. The effect of the bulkiness of the supporting electrolytes on the selectivity of formation of macrolides over diolides was also discussed. In the experiment, the researchers used many compounds, for example, 15-Bromopentadecanoic acid (cas: 56523-59-2Category: bromides-buliding-blocks).

15-Bromopentadecanoic acid (cas: 56523-59-2) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. Category: bromides-buliding-blocks

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Fluorescent indolium dyes for applications in aqueous halide sensing-part 2: the repeated alkylation of Harmane post quaternisation was written by Geddes, C. D.. And the article was included in Dyes and Pigments in 2001.Application In Synthesis of 15-Bromopentadecanoic acid This article mentions the following:

The repeated alkylation of harmane (1-methyl-9H-pyrido[3,4-b]indole) after quaternization has been observed during fusion with 8-bromooctanoic acid (I). This can be explained by two possible competing mechanisms, the electrophilic addition of carboxyalkylating agent to the resonance enamine form of the initial quaternized product and/or oligoester formation between the quaternized product and I. The mechanisms are supported by ¹H NMR, FTIR, and mass spectrometry anal., and by carboxyoctylation of 6-methoxyquinoline. The possibility for controlling the repeated alkylation in nanometer size silica pores, in essence restricted geometry nanometer size reaction vessels, is discussed. In the experiment, the researchers used many compounds, for example, 15-Bromopentadecanoic acid (cas: 56523-59-2Application In Synthesis of 15-Bromopentadecanoic acid).

15-Bromopentadecanoic acid (cas: 56523-59-2) belongs to organobromine compounds. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon–bromine bond is electrophilic, i.e. alkyl bromides are alkylating agents. In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.Application In Synthesis of 15-Bromopentadecanoic acid

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Synthesis of Core-Modified Third-Generation Light-Driven Molecular Motors was written by Berrocal, Jose Augusto;Pfeifer, Lukas;Heijnen, Dorus;Feringa, Ben L.. And the article was included in Journal of Organic Chemistry in 2020.Quality Control of Dimethyl 4,5-dibromophthalate This article mentions the following:

The synthesis and characterization of a series of light-driven third-generation mol. motors featuring various structural modifications at the central aromatic core are presented. We explore a number of substitution patterns, such as 1,2-dimethoxybenzene, naphthyl, 1,2-dichlorobenzene, 1,1′:2′,1”-terphenyl, 4,4”-dimethoxy-1,1′:2′,1”-terphenyl, and 1,2-dicarbomethoxybenzene, considered essential for designing future responsive systems. In many cases, the synthetic routes for both synthetic intermediates and motors reported here are modular, allowing for their post-functionalization. The structural modifications introduced in the core of the motors result in improved solubility and a bathochromic shift of the absorption maxima. These features, in combination with a structural design that presents remote functionalization of the stator with respect to the fluorene rotors, make these novel motors particularly promising as light-responsive actuators in covalent and supramol. materials. In the experiment, the researchers used many compounds, for example, Dimethyl 4,5-dibromophthalate (cas: 859299-66-4Quality Control of Dimethyl 4,5-dibromophthalate).

Dimethyl 4,5-dibromophthalate (cas: 859299-66-4) belongs to organobromine compounds. Organo bromine compounds are versatile compounds and are widely used in diverse fields. Organo bromine derivatives are used in the dye sector, as an indicator in analytical chemistry (Bromothymol blue is a popular indicator). Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. Quality Control of Dimethyl 4,5-dibromophthalate

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Syntheses and first crystal structures of rhenium complexes derived from ω-functionalized fatty acids as model compounds of technetium tracers for myocardial metabolism imaging was written by Jung, Christian M.;Kraus, Werner;Leibnitz, Peter;Pietzsch, Hans-Jurgen;Kropp, Joachim;Spies, Hartmut. And the article was included in European Journal of Inorganic Chemistry in 2002.Quality Control of 15-Bromopentadecanoic acid This article mentions the following:

In an attempt to develop new technetium-based radiopharmaceuticals for the noninvasive diagnosis of myocardial metabolism, the authors synthesized three examples of novel metal-containing fatty acid derivatives according to the “3+1” mixed-ligand and the Schiff base/tricarbonyl design, Re:O[S(CH₂)₂S(CH₂)₂S][S(CH₂)₁₁S(CH₂)₄CO₂H] (7), Re:O[S(CH₂)₂NMe(CH₂)₂S][S(CH₂)₁₄CO₂H] (10) and ReBr(CO)₃[2-py-CH:N(CH₂)₁₁CO₂H] (14). The chelates contain the metal core in the oxidation states +5 (7 and 10) and +1 (14) and are attached to the end-position of a fatty acid chain. The complex formation was accomplished by ligand-exchange reactions with three different rhenium precursors, whereas the inactive rhenium metal was used as a surrogate of the technetium radionuclide. The mol. structures of the fatty acid complexes 7, 10 and 14 were determined by single-crystal x-ray diffraction analyses and impressively show a general problem in technetium tracer research, the significant structural alterations of bioactive mols. by coordination even to small metal chelates. In the experiment, the researchers used many compounds, for example, 15-Bromopentadecanoic acid (cas: 56523-59-2Quality Control of 15-Bromopentadecanoic acid).

15-Bromopentadecanoic acid (cas: 56523-59-2) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. Quality Control of 15-Bromopentadecanoic acid

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Lipid composition, fatty acids and sterols in the seaweeds Ulva armoricana, and Solieria chordalis from Brittany (France): an analysis from nutritional, chemotaxonomic, and antiproliferative activity perspectives was written by Kendel, Melha;Wielgosz-Collin, Gaetane;Bertrand, Samuel;Roussakis, Christos;Bourgougnon, Nathalie;Bedoux, Gilles. And the article was included in Marine Drugs in 2015.Electric Literature of C15H29BrO2 This article mentions the following:

Lipids from the proliferative macroalgae Ulva armoricana (Chlorophyta) and Solieria chordalis (Rhodophyta) from Brittany, France, were investigated. The total content of lipids was 2.6% and 3.0% dry weight for U. armoricana and S. chordalis, resp. The main fractions of S. chordalis were neutral lipids (37%) and glycolipids (38%), whereas U. armoricana contained mostly neutral lipids (55%). Polyunsaturated fatty acids (PUFA) represented 29% and 15% of the total lipids in U. armoricana and S. chordalis, resp. In both studied algae, the phospholipids were composed of PUFA for 18%. In addition, PUFA were shown to represent 9% and 4.5% of glycolipids in U. armoricana and S. chordalis, resp. The essential PUFA were 16:4n-3, 18:4n-3, 18:2n-3, 18:2n-6, and 22:6n-3 in U. armoricana, and 20:4n-6 and 20:5n-3 in S. chordalis. It is important to notice that six 2-hydroxy-, three 3-hydroxy-, and two monounsaturated hydroxy fatty acids were also identified and may provide a chemotaxonomic basis for algae. These seaweeds contained interesting compounds such as squalene, α-tocopherol, cholest-4-en-3-one and phytosterols. The antiproliferative effect was evaluated in vitro on human non-small-cell bronchopulmonary carcinoma line (NSCLC-N6) with an IC₅₀ of 23 μg/mL for monogalactosyldiacylglycerols isolated from S. chordalis and 24 μg/mL for digalactosyldiacylglycerols from U. armoricana. These results confirm the potentialities of valorization of these two species in the fields of health, nutrition and chemotaxonomy. In the experiment, the researchers used many compounds, for example, 15-Bromopentadecanoic acid (cas: 56523-59-2Electric Literature of C15H29BrO2).

15-Bromopentadecanoic acid (cas: 56523-59-2) belongs to organobromine compounds. Organo bromine compounds are versatile compounds and are widely used in diverse fields. Organo bromine derivatives are used in the dye sector, as an indicator in analytical chemistry (Bromothymol blue is a popular indicator). The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Electric Literature of C15H29BrO2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

GC-MS analysis of fatty acids of Irvingia gabonensis seed fat was written by Okore, V. C.;Udeala, O. K.. And the article was included in Nigerian Journal of Natural Products and Medicine in 1997.Quality Control of 15-Bromopentadecanoic acid This article mentions the following:

Dika fat is the name given to the waxy material obtained from the seeds of Irvingia gabonensis (Fam. Irvingiaceae). The fat has been a subject of research in recent years, and it has been evaluated as a component of different drug delivery systems . Despite the impressive properties of this wax as have been established in the earlier studies, information on its chem. composition is rather scanty. Chem. characterization of the wax was done by GC-MS technique. The dika fat was obtained by solvent extraction, using the method described by Udeala et al (1980). A Fisons Trio 200 Quadrupole GC-MS instrument fitted with a 30m × 0.32mm (i.d.) OV-1 capillary column, was used for the anal. The column temperature was programmed to rise from 100°C to 280°C at the rate of 5°/min. The carrier gas was helium flowing at the rate of 1.5ml/min. Ionization voltage of 70eV was applied. The solvent for dika fat was n-hexane. The identity of the components of dika fat was confirmed by a combination of computer-aided identification, the eight peak index of mas spectra as well as co-chromatog. The gas chromatogram of dika fat reveals seven peaks representing major components and about the same number of peaks for the minor components. In the experiment, the researchers used many compounds, for example, 15-Bromopentadecanoic acid (cas: 56523-59-2Quality Control of 15-Bromopentadecanoic acid).

15-Bromopentadecanoic acid (cas: 56523-59-2) belongs to organobromine compounds. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. Quality Control of 15-Bromopentadecanoic acid

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Azide-Modified Membrane Lipids: Synthesis, Properties, and Reactivity was written by Lindner, Sindy;Gruhle, Kai;Schmidt, Rico;Garamus, Vasil M.;Ramsbeck, Daniel;Hause, Gerd;Meister, Annette;Sinz, Andrea;Drescher, Simon. And the article was included in Langmuir in 2017.Computed Properties of C15H29BrO2 This article mentions the following:

In the present work, we describe the synthesis and the temperature-dependent behavior of photoreactive membrane lipids as well as their capability to study peptide-lipid interactions. The modified phospholipids contained an azide group either in the middle part or at the end of an alkyl chain and also differed in the linkage (ester vs. ether) of the 2nd alkyl chain. The temperature-dependent aggregation behavior of the azidolipids was studied using differential scanning calorimetry (DSC), FTIR spectroscopy, and SAXS. Aggregate structures were visualized by stain and cryo-transmission electron microscopy (TEM) and were further characterized by dynamic light scattering (DLS). We showed that the position of the azide group and the type of linkage of the alkyl chain at the sn-2 position of the glycerol influenced the type of aggregates formed as well as their long-term stability: azidolipids P10AzSPC and r12AzSHPC showed the formation of extrudable liposomes, which were stable in size during storage. In contrast, azidolipids that carry a terminal azido moiety either formed extrudable liposomes, which showed time-dependent vesicle fusion (P15AzPdPC), or self-assembled in large sheet-like, non-extrudable aggregates (r15AzPdHPC) where the lipid mols. were arranged in an interdigitated orientation at temperatures below the T_m (L_βI phase). Finally, a P10AzSPC:DMPC mixture was used for photochem.-induced crosslinking experiments with a transmembrane peptide (WAL-peptide) to demonstrate the applicability of the azidolipids for the anal. of peptide/lipid interactions. The efficiency of photocrosslinking was monitored by attenuated total reflection IR spectroscopy and mass spectrometry. In the experiment, the researchers used many compounds, for example, 15-Bromopentadecanoic acid (cas: 56523-59-2Computed Properties of C15H29BrO2).

15-Bromopentadecanoic acid (cas: 56523-59-2) belongs to organobromine compounds. Organo bromine compounds are versatile compounds and are widely used in diverse fields. Organo bromine derivatives are used in the dye sector, as an indicator in analytical chemistry (Bromothymol blue is a popular indicator). Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. Computed Properties of C15H29BrO2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Functionalized N-Heterocyclic Carbene Monolayers on Gold for Surface-Initiated Polymerizations was written by Choi, Yunsoo;Park, Chul Soon;Tran, Hung-Vu;Li, Chien-Hung;Crudden, Cathleen M.;Lee, T. Randall. And the article was included in ACS Applied Materials & Interfaces in 2022.COA of Formula: C15H29BrO2 This article mentions the following:

Although N-heterocyclic carbenes (NHCs) are superior to thiol adsorbates in that they form remarkably stable bonds with gold, the generation of NHC-based self-assembled monolayers (SAMs) typically requires a strong base and an inert atm., which limits the utility of such films in many applications. Herein, we report the development and use of bench-stable NHC adsorbates, benzimidazolium methanesulfonates, for the direct formation of NHC films on gold surfaces under an ambient atm. at room temperature without the need for extraordinary precautions. The generated NHC SAMs were fully characterized using ellipsometry, XPS, polarization modulation IR reflection-absorption spectroscopy (PM-IRRAS), and contact angle measurements, and they were compared to analogous SAMs generated from an NHC bicarbonate adsorbate. Based on these findings, a unique radical initiator α,ω-bidentate azo-terminated NHC adsorbate, NHC15AZO[OMs], was designed and synthesized for the preparation of SAMs on gold surfaces with both NHC headgroups bound to the surface. The adsorbate mols. in NHC15AZO SAMs can exist in a hairpin or a linear conformation depending on the concentration of the adsorbate solution used to prepare the SAM. These conformations were studied by a combination of ellipsometry, XPS, PM-IRRAS, and scanning tunneling microscopy using gold nanoparticles (AuNPs) as a tag material. Moreover, the potential utility of these unique radical-initiating NHC films as surface-initiated polymerization platforms was demonstrated by controlling the thickness of polystyrene brush films grown from azo-terminated NHC monolayer surfaces simply by adjusting the reaction time of the photoinitiated radical polymer growth process. In the experiment, the researchers used many compounds, for example, 15-Bromopentadecanoic acid (cas: 56523-59-2COA of Formula: C15H29BrO2).

15-Bromopentadecanoic acid (cas: 56523-59-2) belongs to organobromine compounds. Many of the organo bromine compounds are relatively nonpolar. Bromine is more electronegative than carbon (2.8 vs 2.5) and hence the carbon in a carbon–bromine bond is electrophilic in nature. Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. COA of Formula: C15H29BrO2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary