Tag: 200-300

In 2018,Tang, Qianyun; Xiao, Wanyue; Li, Jiewei; Chen, Dapeng; Zhang, Yewei; Shao, Jinjun; Dong, Xiaochen published 《A fullerene-rhodamine B photosensitizer with pH-activated visible-light absorbance/fluorescence/photodynamic therapy》.Journal of Materials Chemistry B: Materials for Biology and Medicine published the findings.Application of 1129-28-8 The information in the text is summarized as follows:

The development of smart photosensitizers with tumor microenvironment-activable fluorescence turn-on and singlet oxygen generation plays an important role in tumor bioimaging and photodynamic therapy. Herein, a pH-activable heavy-atom-free photosensitizer (C60-RB) has been successfully synthesized through introducing a fullerene unit onto rhodamine B hydrazide. Under acidic conditions, C60-RB, having a spirolactam structure, can be activated to its ring-opened structure C60-RB-H and thus, visible-light absorbance enhancement, fluorescence turn-on and triplet excited state generation can be accomplished. In the presence of hydrion, the fullerene unit in C60-RB C60-RB-H acting as an intramol. spin converter can cause good intersystem crossing, and the energy gap between S1 and T1 (ΔEST) is lowered to 0.017 eV. Through encapsulation with amphiphilic DSPE-mPEG2000, water-soluble nanoparticles (NPs) of C60-RB are obtained. In vitro experiments indicate that C60-RB NPs are capable of universal cellular uptake and lysosomal activation (pH 4.5-5.0), and they also exhibit excellent photodynamic therapeutic effect. The fluorescence turn-on and efficient singlet oxygen generation enabled by pH-activated C60-RB NPs testify their great potential applications for cancer diagnosis and treatment. The experimental process involved the reaction of Methyl 3-(bromomethyl)benzoate(cas: 1129-28-8Application of 1129-28-8)

Methyl 3-(bromomethyl)benzoate(cas: 1129-28-8) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals.Application of 1129-28-8 The most pervasive is the naturally produced bromomethane.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Recommanded Product: 3141-27-3In 2022 ,《Thienoviologen anolytes for aqueous organic redox flow batteries with simultaneously enhanced capacity utilization and capacity retention》 was published in Journal of Materials Chemistry A: Materials for Energy and Sustainability. The article was written by Liu, Xu; Zhang, Xuri; Li, Guoping; Zhang, Sikun; Zhang, Bingjie; Ma, Wenqiang; Wang, Zengrong; Zhang, Yueyan; He, Gang. The article contains the following contents:

A series of thienoviologen derivatives ([(NPr)2TV]Cl4 and [(OHPr)2TV]Cl2) with a narrow bandgap, high solubility and two-electron transfer properties as anolytes for high-performance aqueous organic redox flow batteries (AORFBs) is reported. Compared with [(OHPr)2TV]Cl2 and other viologen anolytes, [(NPr)2TV]Cl4 showed a higher diffusion coefficient (D, 3.36 x 10-6 cm2 s-1) and electron transfer constant (k0, 0.31 cm s-1). Paired with (ferrocenylmethyl)-trimethylammonium chloride (FcNCl) as the catholyte, the specific capacity of the [(NPr)2TV]Cl4/FcNCl AORFB reached 4.62 A h L-1, and the capacity utilization was up to 86.1%. Moreover, the system also maintained high stability over 300 cycles and delivered 87.9% capacity retention and 99.96% capacity retention per cycle. The simultaneously enhanced capacity retention and capacity utilization of [(NPr)2TV]Cl4-based AORFBs were attributed to the high D and k0, resulting from the smaller mol. volume (583.38 Å3) and appropriate dihedral angle (∼18.37°) between the pyridines. The experimental process involved the reaction of 2,5-Dibromothiophene(cas: 3141-27-3Recommanded Product: 3141-27-3)

2,5-Dibromothiophene(cas: 3141-27-3) , is mainly used as pharmaceutical intermediate and synthesis intermediate. 2,5-Dibromothiophene polymerizes by debromination with magnesium catalyzed by nickel compounds to form poly(2,5- thienylene) .Recommanded Product: 3141-27-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Bhattarai, Ajaya; Saha, Bidyut; Jaffari, Zeeshan Haider; Rub, Malik Abdul; Alghamdi, Yousef G.; Kumar, Dileep published an article in 2021. The article was titled 《Analysis of interaction between glutamic acid and ninhydrin in the presence of acetate buffer solvent: Impact of gemini (twin-headed) surfactants》, and you may find the article in Colloids and Surfaces, A: Physicochemical and Engineering Aspects.Synthetic Route of C6H12Br2 The information in the text is summarized as follows:

This study analyses the impact of twin-headed gemini surfactants on the interaction between glutamic acid (Glu) and a ninhydrin (Nin) in an acetate buffer. Analyses were observed using a UV-vis spectrophotometer and values of absorbance were recorded at fixed time intermissions. The impact of parameters such as pH, temperature, [Glu], and [Nin] was examined on reaction in gemini surfactants. Using a conductometric technique, elec. conductivities of pure geminis and their mixed systems were noted. Using these data, thus, cmc values of pure geminis and their mixed system were measured. By varying different parameters, the rate constant (kψ-value) was evaluated on finishing each kinetic run using a computer-based procedure. The study showed that twin-headed gemini surfactants demonstrated an excellent impact on the titled reaction over the aqueous system although 16-4-16 catalyzed the study more among geminis and followed the abilities to catalyze at each concentration as 16-4-16 > 16-5-16 > 16-6-16. Our goal was to assess the impact of varied gemini surfactants on rate constant and thus, a pseudo-phase model for micellar activity was applied. A low pos. value of ΔH# with a large neg. ΔS# was obtained in geminis than for aqueous solutions A probable reaction mechanism is discussed.1,6-Dibromohexane(cas: 629-03-8Synthetic Route of C6H12Br2) was used in this study.

1,6-Dibromohexane(cas: 629-03-8) is generally used to introduce C6 spacer in the molecular architecture. Some of the examples are: synthesis of pyrrolo-tetrathiafulvalene molecular bridge (6PTTF6) to study redox switching behavior of single molecules; synthesis of water-soluble thermoresponsive polylactides.Synthetic Route of C6H12Br2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《A pillar[5]arene-based fluorescent sensor for sensitive detection of L-Met through a dual-site collaborative mechanism》 was written by Yang, Qing-Yu; Zhang, You-Ming; Ma, Xiao-Qiang; Dong, Hong-Qiang; Zhang, Yun-Fei; Guan, Wen-Li; Yao, Hong; Wei, Tai-Bao; Lin, Qi. HPLC of Formula: 629-03-8 And the article was included in Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy in 2020. The article conveys some information:

L-Methionine (L-Met) is one of the essential amino acids in human health, efficiently detect L-Met is a significant issue. Herein, a concept “”dual-site collaborative recognition”” had been successfully introduced into the design and achieved high selective and sensitive recognition of L-Met. In order to realize the “”dual-site collaborative recognition””, the authors rationally designed and synthesized an ester functionalized pillar[5]arene-based fluorescent sensor (SP5). And it shows blue Aggregation-induced emission (AIE) fluorescence. In the SP5, the pillar[5]arene group act as C-H···π interactions site, and ester group serve as multi hydrogen bonding acceptor. The SP5 exhibited high selectivity and sensitivity (2.84 × 10-8 M) towards L-Met based on the collaboration of electron-rich cavernous pillar[5]arene group and ester group through C-H···π and H-bond interactions, resp. This “”dual-site collaborative recognition”” mechanism has been studied by 1H NMR, ESI-MS and theor. calculation including frontier orbital (HOMO and LUMO), electrostatic potential (ESP) and the noncovalent interaction (NCI). These theor. calculations not only support the proposed host-guest recognition mechanism, but also provided visualized information on the “”dual-site collaborative recognition”” mode. Furthermore, the concept “”dual-site collaborative recognition”” is an effective strategy for easily detecting biol. mols. In the experimental materials used by the author, we found 1,6-Dibromohexane(cas: 629-03-8HPLC of Formula: 629-03-8)

1,6-Dibromohexane(cas: 629-03-8) is generally used to introduce C6 spacer in the molecular architecture. Some of the examples are: synthesis of solvent processable and conductive polyfluorene ionomers for alkaline fuel cell applications; synthesis of cross-linkable regioregular poly(3-(5-hexenyl)thiophene) (P3HNT) for stabilizing the film morphology in polymer photovoltaic cells.HPLC of Formula: 629-03-8

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Azine-based polymers with a two-electron redox process as cathode materials for organic batteries》 was published in Journal of Materials Chemistry A: Materials for Energy and Sustainability in 2020. These research results belong to Acker, Pascal; Speer, Martin E.; Woessner, Jan S.; Esser, Birgit. COA of Formula: C8H8Br2 The article mentions the following:

There is a growing interest in organic-based cathode materials for batteries due to their higher sustainability, low toxicity, and energy-efficient production and recycling. Organic p-type compounds that undergo two reversible oxidations are relatively rare, but can provide a higher specific capacity compared to mols. undergoing one-electron processes. herein azine (N-N-linked diimine)-based polymers are presented featuring two reversible oxidations at attractive potentials of 2.9 and 3.3 V vs. Li/Li+. A cross-linked and end-capped azine-based polymer provided good cycling stability in a Li-based half cell and an available specific capacity of 133 mA h g-1 paired with a high rate performance ≤ 100C rate. the study introduces azines as attractive cathode-active battery materials. In addition to this study using 1,4-Bis(bromomethyl)benzene, there are many other studies that have used 1,4-Bis(bromomethyl)benzene(cas: 623-24-5COA of Formula: C8H8Br2) was used in this study.

1,4-Bis(bromomethyl)benzene(cas: 623-24-5) belongs to organobromine compounds.The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. COA of Formula: C8H8Br2 Dehydrobromination, Grignard reactions, reductive coupling, Wittig reaction, and several nucleophilic substitution reactions are some of the principal reactions which involve organic bromides.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Conjugation-extended viologens with thiophene derivative bridges: near-infrared electrochromism, electrofluorochromism, and smart window applications》 was published in Journal of Materials Chemistry C: Materials for Optical and Electronic Devices in 2020. These research results belong to Chang, Meijuan; Chen, Weinan; Xue, Haodong; Liang, Dingli; Lu, Xuefeng; Zhou, Gang. Recommanded Product: 2,5-Dibromothiophene The article mentions the following:

Two types of thiophene derivatives, i.e., thiophene (T) and 3,4-ethylenedioxylthiophene (ET) with a single thiophene ring, and thieno[3,2-b]thiophene (TT) and 2,2′-bithiophene (BT) with double thiophene rings, have been inserted between the two pyridinium units of an octyl viologen (V). The effective conjugation lengths of the resulting thienoviologens TV, ETV, TTV, and BTV have been successfully extended. Unlike a traditional alkyl viologen, which always serves as a fluorescence quencher, all four thienoviologens exhibit intense photoluminescence (PL). The bathochromic shifts in both absorption and PL spectra are more pronounced in TTV and BTV with double thiophene rings as compared with TV and ETV with a single thiophene bridge. Moreover, upon applying a neg. potential, all four thienoviologens display significant changes in both absorption and PL spectra, indicating their electrochromic (EC) and electrofluorochromic (EFC) properties. Addnl., the EC response can be found not only in the visible but also in the near-IR (NIR) region. Although TTV and BTV with longer conjugated bridges exhibit more extended effective conjugation lengths and higher PL quantum yields, the EC and EFC devices based on TV and ETV gels display better performance than that for TTV and BTV owing to the faster charge and mass transport for smaller mols. Consequently, a better comprehensive property is achieved by the ETV-based gel, which demonstrates fast coloration (1.9 s), high color contrast (87%), and high coloration efficiency (521 cm2 C-1) in the EC device with high fluorescence contrast ratio (Ion/Ioff = 221) in the EFC device. Furthermore, two smart windows have been fabricated to utilize their different driving potentials. Upon increasing the potential, the “”window flower”” in the first device blossoms out with gradually changing petal colors, while the other dual-functional smart window can be adjusted between flower decoration and light blocking functions. The experimental process involved the reaction of 2,5-Dibromothiophene(cas: 3141-27-3Recommanded Product: 2,5-Dibromothiophene)

2,5-Dibromothiophene(cas: 3141-27-3) , is mainly used as pharmaceutical intermediate and synthesis intermediate. 2,5-Dibromothiophene may be used in the preparation of soluble α,ω-diformyl-a-oligothiophenes.Recommanded Product: 2,5-Dibromothiophene

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Enzyme activity of thiophene-fluorene based-copolymer blended with urease in thin films》 was published in Colloids and Surfaces, A: Physicochemical and Engineering Aspects in 2020. These research results belong to Rodrigues, Rebeca da Rocha; de Aquino, Tamires Pedrali; Caseli, Luciano; Peres, Laura Oliveira. Name: 2,5-Dibromothiophene The article mentions the following:

Enzyme activity can be boosted if the mol. architecture of films is manipulated. In this paper, we show an alternative way to immobilize the enzyme urease in a matrix composed of the copolymer poly[(9,9-dioctylfluorene)-co-thiophene] by using the spin coating method. The films were characterized with Fluorescence, UV-vis, and IR spectroscopies, confirming not only the adsorption of the enzyme, but also the maintenance of its secondary structure. Enzyme activity of the blended films was evaluated in terms of hydrolysis of urea as a heterogeneous catalyst. As measured with UV-vis spectroscopy, the blended films presented substrate-enzyme affinity in relation to the Langmuir-Blodgett method, which may be important for the production of enzymic sensors with enhanced performance. This increase was related to the configurational disorder in the copolymer/enzyme blend with their chains being intertwined, facilitating the access of urea to the catalytic site of the enzyme. The experimental part of the paper was very detailed, including the reaction process of 2,5-Dibromothiophene(cas: 3141-27-3Name: 2,5-Dibromothiophene)

2,5-Dibromothiophene(cas: 3141-27-3) , is mainly used as pharmaceutical intermediate and synthesis intermediate. 2,5-Dibromothiophene may be used in the preparation of soluble α,ω-diformyl-a-oligothiophenes.Name: 2,5-Dibromothiophene

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

The author of 《Twelve 4-(4-methoxyphenyl)piperazin-1-ium salts containing organic anions: supramolecular assembly in one, two and three dimensions》 were Kiran Kumar, Haruvegowda; Yathirajan, Hemmige S.; Foro, Sabine; Glidewell, Christopher. And the article was published in Acta Crystallographica, Section E: Crystallographic Communications in 2019. SDS of cas: 586-76-5 The author mentioned the following in the article:

Twelve 4-(4-methoxyphenyl)piperazin-1-ium salts containing organic anions have been prepared and structurally characterized. The monohydrated benzoate, 4-fluorobenzoate, 4-chlorobenzoate and 4-bromobenzoate salts, C11H17N2O+·C7H5O2-·H2O (I), C11H17N2O+·C7H4FO2-·H2O (II), C11H17N2O+·C7H4ClO2-·H2O (III), and C11H17N2O+·C7H4BrO2-·H2O (IV), resp., are isomorphous and all exhibit disorder in the 4-methoxyphenyl unit: the components are linked by N-H···O and O-H···O hydrogen bond to form chains of rings. The unsolvated 2-hydroxybenzoate, pyridine-3-carboxylate and 2-hydroxy-3,5-dinitrobenzoate salts, C11H17N2O+·C7H5O3- (V), C11H17N2O+·C6H4NO2- (VI) and C11H17N2O+·C7H3N2O7- (VII), resp., are all fully ordered: the components of (V) are linked by multiple N-H···O hydrogen bonds to form a chain of rings; those of (VI) are linked into a three-dimensional framework by a combination of N-H···O, C-H···O and C-H···N hydrogen bonds and those of (VII), where the anion has a structure reminiscent of the picrate anion, are linked into a three-dimensional array by N-H···O and C-H···O hydrogen bonds. The hydrogensuccinate and hydrogenfumarate salts, C11H17N2O+·C4H5O4- (VIII) and C11H17N2O+·C4H3O3- (IX), resp., are isomorphous, and both exhibit disorder in the anionic component: N-H···O and O-H···O hydrogen bonds link the ions into sheets, which are further linked by C-H···π(arene) interactions. The anion of the hydrogenmaleate salt, C11H17N2O+·C4H3O3- (X), contains a very short and nearly sym. O···H···O hydrogen bond, and N-H···O hydrogen bonds link the anions into chains of rings. The ions in the trichloroacetate salt, C11H17N2O+·C2Cl3O2- (XI), are linked into simple chains by N-H···O hydrogen bonds. In the hydrated chloranilate salt, 2C11H17N2O+·C6Cl2O42-·2H2O (XII), which crystallizes as a non-merohedral twin, the anion lies across a center of inversion in space group P21/n, and a combination of N-H···O and O-H···O hydrogen bonds generates complex sheets. Comparisons are made with the structures of some related compounds In the experiment, the researchers used many compounds, for example, 4-Bromobenzoic acid(cas: 586-76-5SDS of cas: 586-76-5)

4-Bromobenzoic acid(cas: 586-76-5) has been used to study the metabolic fate of 2-,3-and 4-bromo benzoic acids in rat hepatocytes incubation using high temperature liquid chromatography. It was used in bromine-specific detection of the metabolites of 2-,3-and 4-bromobenzoic acid in the urine and bile of rats by inductively coupled plasma mass spectrometry.SDS of cas: 586-76-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2019,Journal of Materials Chemistry C: Materials for Optical and Electronic Devices included an article by Chen, Qiang; Zajaczkowski, Wojciech; Seibel, Johannes; De Feyter, Steven; Pisula, Wojciech; Muellen, Klaus; Narita, Akimitsu. Recommanded Product: 2675-79-8. The article was titled 《Synthesis and helical supramolecular organization of discotic liquid crystalline dibenzo[hi,st]ovalene》. The information in the text is summarized as follows:

Dibenzo[hi,st]ovalene (DBOV) has emerged as a new polycyclic aromatic hydrocarbon (PAH) with intriguing optical properties with strong red emission. Nevertheless, DBOV derivatives thus far synthesized either had mesityl groups that hinder the π-π stacking of the aromatic cores or showed low solubility, and the self-assembly of DBOVs has not been investigated. In this work, two 3,4,5-tris(dodecyloxy)phenyl (TDOP) groups are introduced at the meso-positions of DBOV in order to enhance its solubility without compromising the intermol. interactions. The obtained DBOV-TDOP forms at elevated temperatures a discotic liquid crystalline phase. Due to π-π-stacking interactions as well as local phase separation between the aromatic cores and the flexible alkoxy side chains, the DBOV-TDOP mols. self-assemble into columnar stacks. In the low temperature phase, the space demanding TDOP substituents induce a rotation of the disks towards each other leading to an exceptionally long helical pitch within the columnar structures. Moreover, scanning tunnelling microscopy (STM) elucidates intriguing self-assembly of DBOV-TDOP at the interface of highly oriented pyrolytic graphite (HOPG) and 1-phenyloctane (PO). Individual mols. are visualized by STM, revealing that the alkyl chains protrude from the surface into the solution and suggesting that a self-assembled bilayer film structure is predominantly formed. The experimental part of the paper was very detailed, including the reaction process of 1-Bromo-3,4,5-trimethoxybenzene(cas: 2675-79-8Recommanded Product: 2675-79-8)

1-Bromo-3,4,5-trimethoxybenzene(cas: 2675-79-8) is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff.Recommanded Product: 2675-79-81-Bromo-3,4,5-trimethoxybenzene can be used to synthesize N,N′-diarylated indolo[3,2-b]carbazole derivatives, which can find applications in electrophotography.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

The author of 《Hydrogen-bonded molecular salts of reduced benzothiazole derivatives with carboxylates: a robust [inline formula omitted] (8) supramolecular motif (even when disordered)》 were Shaibah, Mohammed A. E.; Sagar, Belakavadi K.; Yathirajan, Hemmige S.; Cordes, David B.; Slawin, Alexandra M. Z.; Harrison, William T. A.. And the article was published in Acta Crystallographica, Section E: Crystallographic Communications in 2019. Application of 586-76-5 The author mentioned the following in the article:

The syntheses and structures of five mol. salts of protonated 4,4,7,7-tetramethyl-3a,5,6,7a-tetrahydrobenzothiazol-2-ylamine with diff. deprotonated carboxylic acids (4-methylbenzoic acid, 4-bromobenzoic acid, 3,5-dinitrobenzoic acid, fumaric acid and succinic acid) are reported. They are namely 2-amino-4,4,7,7-tetramethyl-4,5,6,7-tetrahydro-1,3-benzothiazol-3-ium 4-methylbenzoate, C11H19N2S+.C8H7O2-, (I), 2-amino-4,4,7,7-tetramethyl-4,5,6,7-tetrahydro-1,3-benzothiazol-3-ium 4-bromobenzoate, C11H19N2S+.C7H4BrO2-, (II), 2-amino-4,4,7,7-tetramethyl-4,5,6,7-tetrahydro-1,3-benzothiazol-3-ium 3,5-dinitrobenzoate, C11H19N2S+.C7H3N2O6-, (III), bis(2-amino-4,4,7,7-tetramethyl-4,5,6,7-tetrahydro-1,3-benzothiazol-3-ium) fumarate, 2C11H19N2S+.C4H2O42-,(IV), and the 1:1 co-crystal of bis(2-amino-4,4,7,7-tetramethyl-4,5,6,7-tetrahydro-1,3-benzothiazol-3-ium) succinate and 2-amino-4,4,7,7-tetramethyl-4,5,6,7-tetrahydro-1,3-benzothiazol-3-ium hydrogen succinate 4,4,7,7-tetramethyl-3a,5,6,7a-tetrahydrobenzothiazol-2-ylamine, 1.5C11H19N2S+.0.5C4H4O42-.0.5C4H5O4-.0.5C11H18N2S, (V). In every case, the cation protonation occurs at the N atom of the thiazole ring and the six-membered ring adopts a half-chair conformation (in some cases, the deviating methylene groups are disordered over two sets of sites). The C-N bond lengths of the nominal -NH+=C-NH2 fragment of the cation are indistinguishable, indicating a significant contribution of the -NH-C=N+H2 resonance form to the structure. The packing for (I)-(V) features a robust local R22(8) loop motif in which the cation forms two near-linear N-H…O hydrogen bonds from the N+-H group and syn H atom of the amine group to the carboxylate group of an adjacent anion [(V) shows disorder of one of these bonds over N-H…O and N…H-O contributors but the same R22(8) loop results for both disorder components]. The anti H atom of the -NH2 group also forms an N-H..O hydrogen bond, which results in [001] chains in (I) and (II), isolated centrosym.tetramers in (III) and [100] chains in (IV) and (V). Hirshfeld fingerprint plots and contact percentages for the different types of contacts of the cations are discussed. After reading the article, we found that the author used 4-Bromobenzoic acid(cas: 586-76-5Application of 586-76-5)

4-Bromobenzoic acid(cas: 586-76-5) has been used to study the metabolic fate of 2-,3-and 4-bromo benzoic acids in rat hepatocytes incubation using high temperature liquid chromatography.Application of 586-76-5 It was used in bromine-specific detection of the metabolites of 2-,3-and 4-bromobenzoic acid in the urine and bile of rats by inductively coupled plasma mass spectrometry.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary