Tag: 100-200

In 2019,Chemical Communications (Cambridge, United Kingdom) included an article by Tanini, Damiano; Lupori, Beatrice; Malevolti, Gianni; Ambrosi, Moira; Nostro, Pierandrea Lo; Capperucci, Antonella. Safety of Methyl 3-bromopropanoate. The article was titled 《Direct biocatalysed synthesis of first sulfur-, selenium- and tellurium- containing L-ascorbyl hybrid derivatives with radical trapping and GPx-like properties》. The information in the text is summarized as follows:

6-O-L-Ascorbyl selenoesters, thioesters and telluroesters, e.g., I, II, and III, resp., can be efficiently and directly prepared from L-ascorbic acid and suitable functionalized chalcogenoesters through lipase-catalyzed transesterification reactions. Novel synthesized L-ascorbyl derivatives exhibited remarkable chain breaking and glutathione peroxidase-like activities. The experimental part of the paper was very detailed, including the reaction process of Methyl 3-bromopropanoate(cas: 3395-91-3Safety of Methyl 3-bromopropanoate)

Methyl 3-bromopropanoate(cas: 3395-91-3) belongs to bromides. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon–bromine bond is electrophilic, i.e. alkyl bromides are alkylating agents.Safety of Methyl 3-bromopropanoate

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2019,Chemical Communications (Cambridge, United Kingdom) included an article by Zhou, Quan-Quan; Dusel, Simon Josef Siegfried; Lu, Liang-Qiu; Konig, Burkhard; Xiao, Wen-Jing. Related Products of 7051-34-5. The article was titled 《Alkenylation of unactivated alkyl bromides through visible light photocatalysis》. The information in the text is summarized as follows:

Two visible-light driven alkenylation reactions of unactivated alkyl bromides, which were enabled by the use of Ir(dF(CF3)ppy)2(dtbbpy)PF6 as the photocatalyst and (TMS)3SiH as the atom transfer reagent to activate the alkyl bromides, were described for the first time. These protocols can be used to produce a variety of alkenes from easily available feedstock with good reaction efficiency and high chemoselectivity under mild reaction conditions. To further demonstrate the applicability of the present strategy, the alkenylation of bioactive mols. and glycosyl bromides, as well as the alkynylation of unactivated alkyl bromides, was proven to be feasible. In addition to this study using (Bromomethyl)cyclopropane, there are many other studies that have used (Bromomethyl)cyclopropane(cas: 7051-34-5Related Products of 7051-34-5) was used in this study.

(Bromomethyl)cyclopropane(cas: 7051-34-5) is used as a synthetic building block for the introduction of the cyclopropylmethyl group. It was also used in the synthesis of 1,4-dienes via iron-catalyzed cross-coupling with alkenyl Grignard reagents.Related Products of 7051-34-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Computed Properties of C7H5BrOIn 2019 ,《Tandem Knoevenagel-Michael-cyclocondensation reaction of malononitrile, various aldehydes and barbituric acid derivatives using isonicotinic acid as an efficient catalyst》 appeared in Progress in Chemical and Biochemical Research. The author of the article were Moosavi-Zare, Ahmad Reza; Goudarziafshar, Hamid; Jalilian, Zahra. The article conveys some information:

Preparation of pyrano[2,3-d]pyrimidine dione derivatives I (R = H, Me; R1 = C6H5, 4-BrC6H4, 2,3-(Cl2)C6H3, etc.) by the tandem Knoevenagel-Michaelcyclocondensation reaction of malononitrile, various aldehydes R1CHO and barbituric acid derivatives like barbituric acid and 1,3-dimethylbarbituric acid in the presence of isonicotinic acid as an efficient organocatalyst has been described. After reading the article, we found that the author used o-Bromobenzaldehyde(cas: 6630-33-7Computed Properties of C7H5BrO)

o-Bromobenzaldehyde(cas: 6630-33-7) is used in L-threonine aldolase-catalyzed enantio/diastereoselective aldol reactions.Computed Properties of C7H5BrOIt is also used in L-threonine aldolase-catalyzed enantio and diastereoselective aldol reactions. Further, it reacts with trichloromethane to prepare 1-(2-bromo-phenyl)-2,2,2-trichloro-ethanol.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

The author of 《In situ generation of radical initiators using amine-borane complexes for carbohalogenation of alkenes》 were Liautard, Virginie; Delgado, Marine; Colin, Boris; Chabaud, Laurent; Michaud, Guillaume; Pucheault, Mathieu. And the article was published in Chemical Communications (Cambridge, United Kingdom) in 2022. Electric Literature of C4H6BrFO2 The author mentioned the following in the article:

Atom transfer radical addition of alkyl halides to alkenes was developed using a low amount of a stable initiator, amine borane complexes. Thanks to a slow hydroboration step, the overall carbohalogenation process led to good isolated yields. The experimental part of the paper was very detailed, including the reaction process of Ethylbromofluoroacetate(cas: 401-55-8Electric Literature of C4H6BrFO2)

Ethylbromofluoroacetate(cas: 401-55-8) is a member of organofluorine compounds. Organofluorine compounds, which have carbon-fluorine bonds, show unique features such as high thermal and chemical stability, high surface activity, no light-absorbing ability, high pharmacological effect, and so on. Owing to their specific characters, they are indispensable chemicals for industry and our daily lives.Electric Literature of C4H6BrFO2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

The author of 《Catalyst-Transfer Suzuki-Miyaura Condensation Polymerization of Stilbene Monomer: Different Polymerization Behavior Depending on Halide and Aryl Group of ArPd(tBu3P)X Initiator》 were Nojima, Masataka; Kamigawara, Takeru; Ohta, Yoshihiro; Yokozawa, Tsutomu. And the article was published in Journal of Polymer Science, Part A: Polymer Chemistry in 2019. Related Products of 583-69-7 The author mentioned the following in the article:

We report Suzuki-Miyaura coupling polymerization of tetraalkoxy-substituted 4-bromostilbene-4′-boronic acid 1 with several t-Bu3P-ligated Pd initiators; this is the first example of catalyst-transfer condensation polymerization (CTCP) of a monomer containing a carbon-carbon double bond. When o-tolylPd(tBu3P)Br was used as the initiator, the o-tolyl group was not introduced at the polymer end, but polymer with boronic acid at one end and bromine at the other was obtained. However, when we employed stilbenePd(tBu3P)I generated in situ from iodostilbene and Pd(tBu3P)G2 precatalyst, or isolated ArPd(tBu3P)X (Ar, X = Ph, I; o-tolyl, I; and Ph, Br), the aryl group was introduced at the polymer end, indicating that CTCP of 1 proceeded. Therefore, the iodide and aryl group of the Pd initiator complex is crucial for CTCP of 1. However, the mol. weight distribution of the obtained polymer was broad, possibly because coordination of the carbon-carbon double bond of 1 to ArPd(tBu3P)I resulted in slow initiation. © 2018 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym. Chem. 2018. After reading the article, we found that the author used 2-Bromobenzene-1,4-diol(cas: 583-69-7Related Products of 583-69-7)

2-Bromobenzene-1,4-diol(cas: 583-69-7) belongs to organobromine compounds.Most of the natural organobromine compounds are produced by marine organisms , and several brominated metabolites with antibacterial , antitumor , antiviral , and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. Related Products of 583-69-7 In contrast, terrestrial plants account only for a few bromine-containing compounds.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2019,Physica B: Condensed Matter (Amsterdam, Netherlands) included an article by Satheeshchandra, S.; Haleshappa, D.; Rohith, Sandhyashree; Jayarama, A.; Shetty, Nandakumar. Related Products of 6630-33-7. The article was titled 《Novel benzofuran based chalcone material for potential nonlinear optical application》. The information in the text is summarized as follows:

A novel nonlinear optical material, (2E)-1-(1-benzofuran-2-yl)-3-(2-bromophenyl) prop-2-en-1-one monohydrate, is synthesized and crystals are grown at ambient temperature using solution growth method. Spectroscopy techniques such as FT-IR, FT-Raman and 1H NMR are used to confirm the presence of functional groups in the grown crystals. These crystals are crystallized in non-centrosym. orthorhombic structure with a space group P212121 and the powder second harmonic generation (SHG) test shows that the SHG efficiency of these crystals are 2.03 times that of KDP. UV-Vis-NIR studies of these crystal shows maximum optical transparency in the complete visible and near IR spectral region. The TGA/DTA anal. reveals that the material manifests good thermal stability (280.8 °C) as well. The nature of mol. interactions and their quant. role towards the crystal packing is being studied using Hirshfeld surface and 2-D fingerprint anal. The advantages of these crystals lie mainly in the ease of growing crystals, low cutoff wavelength (486 nm), and large SHG efficiency with good thermal stability and this makes the material promising for competent frequency doubling of laser. In the part of experimental materials, we found many familiar compounds, such as o-Bromobenzaldehyde(cas: 6630-33-7Related Products of 6630-33-7)

o-Bromobenzaldehyde(cas: 6630-33-7) is used in L-threonine aldolase-catalyzed enantio/diastereoselective aldol reactions.Related Products of 6630-33-7It is a key starting material in the total synthesis of an anticancer agent, (-)-taxol.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

The author of 《A three-component difunctionalization of N-alkenyl amides via organophotoredox radical-polar crossover》 were Dhungana, Roshan K.; Granados, Albert; Sharique, Mohammed; Majhi, Jadab; Molander, Gary A.. And the article was published in Chemical Communications (Cambridge, United Kingdom) in 2022. Application of 401-55-8 The author mentioned the following in the article:

Herein, a three-component organophotoredox coupling of N-alkenyl amides I [R1 = Me, R2 = H, Me; R1R2 = (CH2)3, (CH2)5; R3 = H, Me] with α-bromocarbonyls II (R4 = F, Me; R5 = EtO, Et2N) and various nucleophiles NuH (Nu = OH, 4-ClC6H4S, 2-pyrimidinylthio, EtO, N3, etc.) to give the corresponding compounds III is reported. This transition metal-free difunctionalization protocol installs sequential C-C and C-Y (Y = S/O/N) bonds in alkenes. This reaction works with terminal and internal alkenes containing both cyclic and acyclic amides via radical-polar crossover. In the experiment, the researchers used many compounds, for example, Ethylbromofluoroacetate(cas: 401-55-8Application of 401-55-8)

Ethylbromofluoroacetate(cas: 401-55-8) is a member of organofluorine compounds. Organofluorine compounds, which have carbon-fluorine bonds, show unique features such as high thermal and chemical stability, high surface activity, no light-absorbing ability, high pharmacological effect, and so on. Owing to their specific characters, they are indispensable chemicals for industry and our daily lives.Application of 401-55-8

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2019,Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy included an article by Liu, Ji-lin; Xu, Chun-ling; Yang, Ting; Hu, Zhi-ru; Zhang, Zhi-quan; Feng, Guo-dong. Reference of Ethyl 4-bromobutyrate. The article was titled 《Developed a novel sensor based on fluorescent graft conjugated polymer for the determination of aristolochic acid in traditional Chinese medicine》. The information in the text is summarized as follows:

A novel fluorescent graft conjugated polymer (poly (2, 5-bis (Polyethylene glycol oxybutyrate)-1, 4-phenylethynylene-alt-1, 4-phenyleneethynylene, PPE-OB-PEG)) has been designed and synthesized for the determination of aristolochic acid (AA). The detection conditions and detection characters of PPE-OB-PEG were systematically explored in this work. The fluorescence intensity of PPE-OB-PEG changes with the different concentration of AA. PPE-OB-PEG has a good linear range towards AA from 1.00×10-7 to 8.00×10-5 mol L-1 and the limit of detection (LOD) is 3.00×10-8 mol L-1 (S/N = 3). PPE-OB-PEG have been applied to detect AA in traditional Chinese medicine samples and the results are satisfactory. The exptl. results show that PPE-OB-PEG can be used as a fluorescence probe for rapid and sensitive detection of AA. In addition to this study using Ethyl 4-bromobutyrate, there are many other studies that have used Ethyl 4-bromobutyrate(cas: 2969-81-5Reference of Ethyl 4-bromobutyrate) was used in this study.

Ethyl 4-bromobutyrate(cas: 2969-81-5) belongs to bromides. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon–bromine bond is electrophilic, i.e. alkyl bromides are alkylating agents.Reference of Ethyl 4-bromobutyrate

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2017,Rodriguez Castanon, Jesus; Sano, Natsuhiro; Shiotsuki, Masashi; Sanda, Fumio published 《Synthesis of poly(1-chloro-2-arylacetylene)s with high cis-content and examination of their absorption/emission properties》.Journal of Polymer Science, Part A: Polymer Chemistry published the findings.Safety of 1-Bromo-2-isopropylbenzene The information in the text is summarized as follows:

A series of 1-chloro-2-arylacetylenes [Cl-CC-Ar, Ar = C6H5 (1), C6H4-p-iPr (2), C6H4-p-OiPr (3), C6H4-p-NHC(O)OtBu (4), and C6H4-o-iPr (5)] were polymerized using (tBu3P)PdMeCl/silver trifluoromethanesulfonate (AgOTf) and MoCl5/SnBu4 catalysts. The corresponding polymers [poly(1)-poly(5)] with weight-average mol. weights of 6500-690,000 were obtained in 10-91% yields. THF-insoluble parts, presumably high-mol. weight polymers, were formed together with THF-soluble polymers by the Pd-catalyzed polymerization The Pd catalyst polymerized nonpolar monomers 1 and 2 to give the polymers in yields lower than the Mo catalyst, while the Pd catalyst polymerized polar monomers 3 and 4 to give the corresponding polymers in higher yields. The 1H NMR and UV-vis absorption spectra of the polymers indicated that the cis-contents of the Pd-based polymers were higher than those of the Mo-based polymers, and the conjugation length of the Pd-based polymers was shorter than that of the Mo-based polymers. Pd-based poly(5) emitted fluorescence most strongly among poly(1)-poly(5). © 2016 Wiley Periodicals, Inc. J. Polym. Sci., Part A: Polym.Chem. 2016. In the experiment, the researchers used 1-Bromo-2-isopropylbenzene(cas: 7073-94-1Safety of 1-Bromo-2-isopropylbenzene)

1-Bromo-2-isopropylbenzene(cas: 7073-94-1) belongs to organobromine compounds.The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. Safety of 1-Bromo-2-isopropylbenzene The principal reactions for organobromides include dehydrobromination, Grignard reactions, reductive coupling, and nucleophilic substitution.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Product Details of 6630-33-7In 2021 ,《Synthesis of new Schiff bases; Investigation of their in situ catalytic activity for Suzuki C-C coupling reactions and antioxidant activities》 was published in Journal of the Chinese Chemical Society (Weinheim, Germany). The article was written by Yilmaz, Oezguer. The article contains the following contents:

New series of Schiff bases I [R = H, 2-Br, 2,4-di-HOC6H3, etc.] had been synthesized from the reaction between cyclohepta-2,4,6-trien-1-ylmethanamine and different aldehydes, and characterized via using 1H NMR, 13C NMR, FTIR spectroscopy and GC-MS. After the successful synthesis, the in situ catalytic activity of all Schiff bases had been examined for Suzuki C-C cross-coupling reactions using phenylboronic acid, aryl bromides and PdCl2 as a catalyst. Before starting these investigations, reaction conditions were optimized using different bases and solvents. At the end of these reactions, the best efficiency was obtained in Et3N and EtOH. In addition to catalytic investigations, antioxidant activities of all synthesized Schiff bases were examined using DPPH and iron (Fe2+) chelation methods, and IC50 values were calculated While many mols. showed various amounts of antioxidant activity, especially mols. I [R = 2,4-di-HOC6H3, 4-(E)-styryl] showed the best activity compared to butylated hydroxytoluene (BHT) and butylated hydroxyanisole (BHA), which were used as pos. controls, in DPPH and iron chelating methods, resp. In addition to this study using o-Bromobenzaldehyde, there are many other studies that have used o-Bromobenzaldehyde(cas: 6630-33-7Product Details of 6630-33-7) was used in this study.

o-Bromobenzaldehyde(cas: 6630-33-7) is used in L-threonine aldolase-catalyzed enantio/diastereoselective aldol reactions.Product Details of 6630-33-7It is also used in L-threonine aldolase-catalyzed enantio and diastereoselective aldol reactions. Further, it reacts with trichloromethane to prepare 1-(2-bromo-phenyl)-2,2,2-trichloro-ethanol.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary