Bromides-buliding-blocks

Silicon-Carbon Bond Formation via Nickel-Catalyzed Cross-Coupling of Silicon Nucleophiles with Unactivated Secondary and Tertiary Alkyl Electrophiles was written by Chu, Crystal K.;Liang, Yufan;Fu, Gregory C.. And the article was included in Journal of the American Chemical Society in 2016.Reference of 57293-19-3 This article mentions the following:

A wide array of cross-coupling methods for the formation of C-C bonds from unactivated alkyl electrophiles were described in recent years. In contrast, progress in the development of methods for the construction of C-heteroatom bonds has lagged; for example, there were no reports of metal-catalyzed cross-couplings of unactivated secondary or tertiary alkyl halides with Si nucleophiles to form C-Si bonds. The authors address this challenge, establishing that a simple, com. available Ni catalyst (NiBr₂璺痙iglyme) can achieve couplings of alkyl bromides with nucleophilic Si reagents under unusually mild conditions (e.g., -20鎺?; especially noteworthy is the authors’ ability to employ unactivated tertiary alkyl halides as electrophilic coupling partners, which is still relatively uncommon in the field of cross-coupling chem. Stereochem., relative reactivity, and radical-trap studies are consistent with a homolytic pathway for C-X bond cleavage. In the experiment, the researchers used many compounds, for example, 1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3Reference of 57293-19-3).

1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3) belongs to organobromine compounds. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon閳ユ彽romine bond is electrophilic, i.e. alkyl bromides are alkylating agents. One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine.Reference of 57293-19-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Nanostructures from Self-Assembling Triazine Tertiary Amine N-Oxide Amphiphiles was written by Beecham, Matthew P.;Clarkson, Guy J.;Hall, Gareth;Marsh, Andrew. And the article was included in ChemPhysChem in 2013.Reference of 954-81-4 This article mentions the following:

A set of amphiphilic tertiary amine N-oxides has been prepared and their self-assembly was observed in aqueous solution by tensiometry, dynamic, and static light scattering. X-ray crystallog. anal. of parent amines and sulfoxide congeners indicated the formation of hydrogen-bonded dimers as the primary assembly unit for formation of vesicles in preference to the compact micelles typical of lauryl dimethylamine N-oxide (LDAO). 6-Benzyloxy-N,N’-bis(5-diethylaminopentylamine oxide)[1,3,5]triazine-2,4-diamine formed a 1 娓璵 vesicle observed to entrap fluorescein. The [1,3,5]triazine core thus allowed for the variation of the new self-assembled structures from nano- to micrometer length scales. In the experiment, the researchers used many compounds, for example, N-(5-Bromopentyl)phthalimide (cas: 954-81-4Reference of 954-81-4).

N-(5-Bromopentyl)phthalimide (cas: 954-81-4) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. When the molecular ion is detected, the bromine and chlorine isotope patterns are very distinct, but caution is to be exercised for certain mixed chlorinated/brominated compounds, which can look similar to homohalogen patterns.Reference of 954-81-4

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Effect of Electron-Withdrawing Chlorine Substituent on Morphological and Photovoltaic Properties of All Chlorinated D-A-Type Quinoxaline-Based Polymers was written by Lee, Seok Woo;Shin, Hee Jeong;Park, Byoungwook;Shome, Sanchari;Whang, Dong Ryeol;Bae, Hyemin;Chung, Sein;Cho, Kilwon;Ko, Seo-Jin;Choi, Hyosung;Chang, Dong Wook. And the article was included in ACS Applied Materials & Interfaces in 2022.Related Products of 128-08-5 This article mentions the following:

The choice of the chlorine (Cl) atom as an electron-withdrawing substituent in conjugated polymers leads to a higher potential in the commercialization of polymer solar cells than its fluorine counterpart because of the versatility and cost-effectiveness of the chlorination process. In addition, the population and location of Cl substituents can significantly influence the photovoltaic characteristics of polymers. In this study, three chlorinated quinoxaline-based polymers were invented to examine the numerical and positioning effects of the Cl atom on their photovoltaic characteristics. The number of Cl substituents in the reference polymer, PBCl-Qx, was adjusted to three: two Cl atoms in the benzodithiophene-type D unit and one Cl atom in the quinoxaline-type A unit. Subsequently, two more Cl atoms were selectively introduced at the 4- and 5-positions of the alkylated thiophene moieties at the 2,3-positions of the quinoxaline moiety in PBCl-Qx to obtain the addnl. polymers PBCl-Qx4Cl and PBCl-Qx5Cl, resp. The conventional PBCl-Qx4Cl device exhibited a better power conversion efficiency (PCE) of 12.95% as compared to those of PBCl-Qx (12.44%) and PBCl-Qx5Cl (11.82%) devices. The highest PCE of the device with PBCl-Qx4Cl was ascribed to an enhancement in the open-circuit voltage and fill factor induced by the deeper energy level of the HOMO and the favorable morphol. features in its blended film with Y6. In the experiment, the researchers used many compounds, for example, 1-Bromopyrrolidine-2,5-dione (cas: 128-08-5Related Products of 128-08-5).

1-Bromopyrrolidine-2,5-dione (cas: 128-08-5) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.Related Products of 128-08-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Development of the first menthane-based chiral bis(锜?allylpalladium) catalysis: asymmetric allylation of imines was written by Fernandes, Rodney A.;Chaudhari, Dipali A.. And the article was included in European Journal of Organic Chemistry in 2012.Application of 28322-40-9 This article mentions the following:

A new ethylidene menthane-based chiral 锜?allylpalladium complex catalyzes the asym. allylation of various imines with allyltributylstannane and 1 equivalent of water to give chiral homoallylamines in good yields and enantioselectivities. The reaction was carried out essentially under neutral conditions and displayed a good transfer of chiral information from the menthane skeleton through the formation of a bis(锜?allylpalladium) species. This is the first example of menthane-based chiral bis(锜?allylpalladium) catalysis. In the experiment, the researchers used many compounds, for example, Isopentyltriphenylphosphonium bromide (cas: 28322-40-9Application of 28322-40-9).

Isopentyltriphenylphosphonium bromide (cas: 28322-40-9) belongs to organobromine compounds. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. Application of 28322-40-9

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Near-infrared non-fused ring acceptors with light absorption up to 1000 nm for efficient and low-energy loss organic solar cells was written by Luo, Dou;Zhang, Yuniu;Li, Lanqing;Shan, Chengwei;Liu, Qian;Wang, Zhaojin;Choy, Wallace C. H.;Kyaw, Aung Ko Ko. And the article was included in Materials Today Energy in 2022.Related Products of 128-08-5 This article mentions the following:

It is challenging to afford both high-performance and low-energy loss (Eloss) organic solar cells (OSCs) based on near-IR (NIR) non-fused ring electron acceptors (NFREAs) with ultra-narrow bandgap. Herein, three simple NFREAs (C6OT-4F, C6EDOT-4F and PDOT-4F) with absorption up to 1000 nm are developed by using alkoxy substituted thiophene derivatives core connected to fluorinated 1,1-dicyanomethylene-3-indanone (DFIC) terminals through 4H-cyclopenta[1,2-b:5,4-b]dithiophene (CPDT) bridge. It is found that fine tuning central thiophene derivatives can surprisingly lead to different photoelec. properties and the device performances. Compared with C6EDOT-4F and PDOT-4F, C6OT-4F shows a blue-shifted absorption and an elevated LUMO level, which is beneficial for boosting Voc. As a result, optimal devices based on PTB7-Th:C6OT-4F achieve a preferable efficiency of 9.83% with a low Eloss of 0.47 eV, which is the lowest Eloss among the NFREA-based OSCs with PCE >9% and optoelectronic response over 1000 nm. This work portrays the design concept of ultra-narrow bandgap NFREAs for efficient OSCs as well as low energy loss and exploration of semitransparent photoelec. devices. In the experiment, the researchers used many compounds, for example, 1-Bromopyrrolidine-2,5-dione (cas: 128-08-5Related Products of 128-08-5).

1-Bromopyrrolidine-2,5-dione (cas: 128-08-5) belongs to organobromine compounds. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon閳ユ彽romine bond is electrophilic, i.e. alkyl bromides are alkylating agents. Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.Related Products of 128-08-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

The Role of Long-Alkyl-Group Spacers in Glycolated Copolymers for High-Performance Organic Electrochemical Transistors was written by Tan, Ellasia;Kim, Jingwan;Stewart, Katherine;Pitsalidis, Charalampos;Kwon, Sooncheol;Siemons, Nicholas;Kim, Jehan;Jiang, Yifei;Frost, Jarvist M.;Pearce, Drew;Tyrrell, James E.;Nelson, Jenny;Owens, Roisin M.;Kim, Yun-Hi;Kim, Ji-Seon. And the article was included in Advanced Materials (Weinheim, Germany) in 2022.Reference of 128-08-5 This article mentions the following:

Semiconducting polymers with oligoethylene glycol (OEG) sidechains have attracted strong research interest for organic electrochem. transistor (OECT) applications. However, key mol. design rules for high-performance OECTs via efficient mixed electronic/ionic charge transport are still unclear. In this work, new glycolated copolymers (gDPP-TTT and gDPP-TTVTT) with diketopyrrolopyrrole (DPP) acceptor and thiophene (T) and vinylene (V) thiophene-based donor units are synthesized and characterized for accumulation mode OECTs, where a long-alkyl-group (C₁₂) attached to the DPP unit acts as a spacer distancing the OEG groups from the polymer backbone. gDPP-TTVTT shows the highest OECT transconductance (61.9 S cm^-1) and high operational stability, compared to gDPP-TTT and their alkylated counterparts. Surprisingly, gDPP-TTVTT also shows high electronic charge mobility in a field-effect transistor, suggesting efficient ion injection/diffusion without hindering its efficient electronic charge transport. The elongated donor unit (TTVTT) facilitates hole polaron formation to be more localized to the donor unit, leading to faster and easier polaron formation with less impact on polymer structure during OECT operation, as opposed to the TTT unit. This is supported by mol. dynamics simulation. These simultaneously high electronic and ionic charge-transport properties are achieved due to the long-alkyl-group spacer in amphipathic sidechains, providing an important mol. design rule for glycolated copolymers. In the experiment, the researchers used many compounds, for example, 1-Bromopyrrolidine-2,5-dione (cas: 128-08-5Reference of 128-08-5).

1-Bromopyrrolidine-2,5-dione (cas: 128-08-5) belongs to organobromine compounds. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. Many of the alkyl bromine derivatives are excellent alkylating agents since bromides are good leaving groups. Tribromides, like tetrabutylammonium tribromide, are used as a solid source of bromine. N-bromosuccimide (NBS) is used for the selective bromination of allylic bonds.Reference of 128-08-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

The addition of halogen derivatives to allylbenzenes in the presence of peroxides; preparation of 锠?bromopropylbenzenes was written by Quelet, Raymond;Durand-Dran, Raymonde;Pineau, Robert. And the article was included in Compt. rend. in 1957.Electric Literature of C10H13BrO This article mentions the following:

Despite the presence of a normally unreactive double bond, RC₆H₄CH₂CH:CH₂ (I) were converted to RC₆H₄CH₂CH₂Br (II) by treatment with HBr under the conditions of the Kharasch reaction (cf. C.A. 41, 4769h). Although no details are given, CCl₄ and CHBr₃ also added to I in the presence of Ac₂O to give satisfactory yields of the polyhalogenated butylbenzenes. I (in C₆H₆ solution only if the II crystallized) were treated gradually with 4-8% Bz₂O₂ in C₆H₆ or Ac₂O in Et₂O and saturated with dry HBr gas at 0-10鎺?in a long cylindrical tube. The saturated mixture was freed of excess HBr at room temperature with a stream of air, washed, neutralized, treated with Na₂S₂O₄ solution, and distilled in vacuo. The II were identified by conversion to RC₆H₄CH₂CH₂CH₂CO₂H (III) by formation of their Grignard compounds in Et₂O or tetrahydrofuran or in some cases via the nitriles. The following II were prepared (R, b.p./mm., % yield, and m.p. of III given): H, 113-15鎺?16, 80, 50鎺? o-Me, 75-6鎺?0.35, 66, 59-60鎺? m-Me, 85-6鎺?1.1, 80, 37.5鎺? p-Me, 75-8鎺?0.7, 70, 58鎺? p-MeO, 85鎺?0.8, 70, 58鎺? 3,4-di-MeO (IV), 108-10鎺?0.01, 55, -. III were formed in good yields except from IV where demethylation took place in the Grignard preparation In the experiment, the researchers used many compounds, for example, 1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3Electric Literature of C10H13BrO).

1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.Electric Literature of C10H13BrO

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Phosphabarrelenes as ligands in rhodium-catalyzed hydroformylation of internal alkenes essentially free of alkene isomerization was written by Fuchs, Evelyn;Keller, Manfred;Breit, Bernhard. And the article was included in Chemistry – A European Journal in 2006.Category: bromides-buliding-blocks This article mentions the following:

Despite significant research efforts in the past, one of the remaining problems to be solved in industrially important hydroformylation is the chemoselective low-pressure hydroformylation of internal alkenes. The authors prepare a new class of phosphabarrelenes (I, R = Ph (26%, 4a), i-Pr (35%, 4b), 2,4-xylyl (47%, 4c)) by Diels Alder reactions of benzyne with phosphabenzenes. Studies of the coordination properties of I, as well as results obtained in the Rh-catalyzed hydroformylation of cyclic and acyclic internal alkenes are reported. The rhodium/phosphabarrelene catalyst displays a very high activity towards hydroformylation with an unusually low tendency towards alkene isomerization. E.g., phosphabarrelene rhodium-catalyzed hydroformylation (4c/[Rh(CO)₂acac], acac = acetylacetonate) of N-Boc-pyrroline gives exclusively the pyrroline 3-carboxaldehyde. The mol. structures of 4a and two phosphabarrelene rhodium complexes are determined by x-ray crystallog. In the experiment, the researchers used many compounds, for example, 3-Bromo-4-fluorotoluene (cas: 452-62-0Category: bromides-buliding-blocks).

3-Bromo-4-fluorotoluene (cas: 452-62-0) belongs to organobromine compounds. Organo bromine compounds are versatile compounds and are widely used in diverse fields. Organo bromine derivatives are used in the dye sector, as an indicator in analytical chemistry (Bromothymol blue is a popular indicator). Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. Category: bromides-buliding-blocks

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A Robust and Broadly Applicable Cobalt-Catalyzed Cross-Coupling of Functionalized Bench-Stable Organozinc Pivalates with Unsaturated Halides was written by Hammann, Jeffrey M.;Lutter, Ferdinand H.;Haas, Diana;Knochel, Paul. And the article was included in Angewandte Chemie, International Edition in 2017.HPLC of Formula: 474709-71-2 This article mentions the following:

We report a robust and broadly applicable CoCl₂-catalyzed cross-coupling between functionalized aryl and heteroaryl zinc pivalates and various electron-poor aryl and heteroaryl halides (X=Cl, Br, I). Couplings with (E)- or (Z)-bromo- or iodo-alkenes proceed with retention of configuration. Also, alkynyl bromides react with arylzinc pivalates providing arylated alkynes. In the experiment, the researchers used many compounds, for example, Ethyl 4-bromo-2-fluorobenzoate (cas: 474709-71-2HPLC of Formula: 474709-71-2).

Ethyl 4-bromo-2-fluorobenzoate (cas: 474709-71-2) belongs to organobromine compounds. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.HPLC of Formula: 474709-71-2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Imidazopyridine and Pyrazolopiperidine Derivatives as Novel Inhibitors of Serine Palmitoyl Transferase was written by Genin, Michael J.;Gonzalez Valcarcel, Isabel C.;Holloway, William G.;Lamar, Jason;Mosior, Marian;Hawkins, Eric;Estridge, Thomas;Weidner, Jeffrey;Seng, Thomas;Yurek, David;Adams, Lisa A.;Weller, Jennifer;Reynolds, Vincent L.;Brozinick, Joseph T.. And the article was included in Journal of Medicinal Chemistry in 2016.COA of Formula: C6H5BrN2O2 This article mentions the following:

To develop novel treatments for type 2 diabetes and dyslipidemia, we pursued inhibitors of serine palmitoyl transferase (SPT). To this end compounds (I) and (II) were developed as potent SPT inhibitors in vitro. I and II reduce plasma ceramides in rodents, have a slight trend toward enhanced insulin sensitization in DIO mice, and reduce triglycerides and raise HDL in cholesterol/cholic acid fed rats. Unfortunately these mols. cause a gastric enteropathy after chronic dosing in rats. In the experiment, the researchers used many compounds, for example, 6-Amino-5-bromonicotinic acid (cas: 180340-69-6COA of Formula: C6H5BrN2O2).

6-Amino-5-bromonicotinic acid (cas: 180340-69-6) belongs to organobromine compounds. Organo bromine compounds are versatile compounds and are widely used in diverse fields. Organo bromine derivatives are used in the dye sector, as an indicator in analytical chemistry (Bromothymol blue is a popular indicator). Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.COA of Formula: C6H5BrN2O2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary