Computed Properties of C15H12BrNO2SOn May 8, 2006 ,《Synthesis of fused imidazo-pyridine and -azepine derivatives by sequential van Leusen/Heck reactions》 appeared in Tetrahedron Letters. The author of the article were Beebe, Xenia; Gracias, Vijaya; Djuric, Stevan W.. The article conveys some information:
Fused imidazo-pyridine and -azepine derivatives were synthesized using a sequential van Leusen/intramol. Heck protocol. The combination of a multicomponent reaction followed by an intramol. carbon-carbon bond forming reaction generates heterocycles of significant mol. complexity from readily available starting materials in just two steps. In addition to this study using a-Tosyl-(2-bromobenzyl) isocyanide, there are many other studies that have used a-Tosyl-(2-bromobenzyl) isocyanide(cas: 936548-16-2Computed Properties of C15H12BrNO2S) was used in this study.
a-Tosyl-(2-bromobenzyl) isocyanide(cas: 936548-16-2) belongs to organobromine compounds.The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. The principal reactions for organobromides include dehydrobromination, Grignard reactions, reductive coupling, and nucleophilic substitution.Computed Properties of C15H12BrNO2S
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary