90-59-5 Archives - Page 4 of 13 - Bromides-buliding-blocks

Soroceanu, Alina team published research in Materials in 2021 | 90-59-5

90-59-5, 3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes.

3,5-Dibromosalicylaldehyde, also known as 3,5-Dibromosalicylaldehyde, is a useful research compound. Its molecular formula is C7H4Br2O2 and its molecular weight is 279.91 g/mol. The purity is usually 95%.

3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes. 3,5-Dibromosalicylaldehyde can be used in the synthesis of Schiff base and can be used as reactant for synthesis of Schiff base ligands which forms mononuclear complexes with copper(II), nickel(II), zinc(II) and cobalt(II).

3,5-Dibromosalicylaldehyde is a copper complex that has been synthesized from 3,5-dibromosalicylaldehyde and copper chloride. FTIR spectroscopy revealed that the coordination geometry of the copper complex is octahedral with two nitrogen atoms in the equatorial plane. The presence of hydrogen bonding interactions was confirmed by homologous protein adsorption experiments. This chemical structure was determined using X-ray crystallography and fluorescence probe experiments. The copper complex showed high affinity for malonic acid, which is an ester hydrochloride. The molecular mechanism of this interaction is based on adsorption, which occurs through hydrogen bonding interactions and hydrophobic interactions. Structural analysis revealed that the polymeric matrix consists of a three-dimensional network of crosslinked chains, while FTIR analysis indicated a possible disulfide bond between two cysteine residues., Quality Control of 90-59-5

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 90-59-5, formula is C7H4Br2O2, Name is 3,5-Dibromo-2-hydroxybenzaldehyde. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Quality Control of 90-59-5.

Soroceanu, Alina;Stiubianu, George T. research published 《 Siloxane matrix molecularweight influences the properties of nanocomposites based on metal complexes and dielectric elastomer》, the research content is summarized as follows. Siloxane-based elastomers are some of the most sought-after materials for the construction of actuators and equipment for energy harvesting devices. This article focuses on changes of the mech. (breaking stress, breaking strain, Young′s modulus) and dielec. properties for elastomers prepared with silicones, induced by the variation of mol. weight of the matrix, with three different silicone polymers having 60,000 g/mol, 150,000 g/mol, and 450,000 g/mol (from GPC measurements). Multiple siloxane elastomers were crosslinked with methyltriacetoxysilane using the sol-gel route. The dielec. permittivity values of the elastomers were also enhanced with two different complex structures containing siloxane bond and 3d transition metals as filler materials for polydimethylsiloxane polymers with various mol. weights The dielec. spectroscopy tests demonstrated a small decrease (5%) for the values of the dielec. permittivity in relation to increased mol. weight of the siloxane polymer, both for samples prepared with pure polymer and for samples with metal complexes. The samples of nanocomposites showed a >50% increase of dielec. permittivity values relative to samples prepared of pure siloxane elastomer. The thermal tests demonstrated that the nanocomposites retained thermal stability similar with samples prepared of pure siloxane elastomer. The behavior under controlled conditions of humidity showed a trend of increased water vapor sorption with increasing mol. weight but an overall hydrophobic stable character of nanocomposites.

90-59-5, 3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Stangier, Maximilian team published research in Nature Communications in 2021 | 90-59-5

Reference of 90-59-5, 3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes.

Vinyl bromides undergo the Heck reaction, which involves C-C coupling with alkene to give substituted alkenes. 90-59-5, formula is C7H4Br2O2, Name is 3,5-Dibromo-2-hydroxybenzaldehyde. Methyl bromide is a precursor in the manufacture of several chemicals and is employed as a soil sterilant, mainly for seed production. Reference of 90-59-5.

Stangier, Maximilian;Messinis, Antonis M.;Oliveira, Joao C. A.;Yu, Hao;Ackermann, Lutz research published 《 Rhodaelectro-catalyzed access to chromones via formyl C-H activation towards peptide electro-labeling》, the research content is summarized as follows. Herein, a strategy for the sustainable assembly of chromones I (R = H, Cl, ethenyl; R¹ = H, OMe, Ph, Br, etc.; R² = H, Me, diethylaminyl, F, etc.; R¹R² = 7-oxo-dodecahydro-1H-cyclopenta[a]naphthalene-3,4-bis(ylium);R³ = H, Cl, OMe, Me, t-Bu, Br; R²R³ = -(CH=CH-CH=CH)-; R⁴ = Me, Ph, naphthalen-2-yl, (morpholin-4-yl)carbonyl, etc.; R⁵ = t-Bu, Ph, naphthalen-1-yl, 3,5-dimethylphenyl, etc.; R⁴R⁵ = 2-(benzen-2-yl-1-yl)benzen-1-yl, 1-(naphthalen-2-yl-1-yl)naphthalen-2-yl) via electro-formyl C-H activation is presented. The rational design of the rhodaelectro-catalysis is guided by detailed mechanistic insights and provides versatile access to tyrosine-based fluorogenic peptidomimetics.

Reference of 90-59-5, 3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Shkoor, Mohanad team published research in Synlett in 2021 | 90-59-5

Application In Synthesis of 90-59-5, 3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes.

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 90-59-5, formula is C7H4Br2O2, Name is 3,5-Dibromo-2-hydroxybenzaldehyde. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Application In Synthesis of 90-59-5.

Shkoor, Mohanad;Bayari, Raghad research published 《 DMAP-Catalyzed Reaction of Diethyl 1,3-Acetonedicarboxylate with 2-Hydroxybenzylideneindenediones: Facile Synthesis of Fluorenone-Fused Coumarins》, the research content is summarized as follows. The base-catalyzed reaction of di-Et 1,3-acetonedicarboxylate with 2-hydroxybenzylidene indenediones was studied. The reaction provides a facile and expeditious protocol for the synthesis of natural product inspired fluorenone-fused coumarins in good to very good yields. This process resembles a combination of domino Michael-intramol. Knoevenagel-aromatization-lactonization reactions in a single step. Although this reaction operates with many bases, the best yields were obtained with DMAP as a catalyst. This protocol could open new potential avenues for the synthesis of fused coumarins by the reaction of substituted β-keto esters with different 2-(2-hydroxybenzylidenes) of 1,3-dicarbonyl compounds

Application In Synthesis of 90-59-5, 3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Shool, Maryam Taghizadeh team published research in Dalton Transactions in 2022 | 90-59-5

Quality Control of 90-59-5, 3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes.

Organic compounds having carbon bonded to bromine are called organic bromides. 90-59-5, formula is C7H4Br2O2, Name is 3,5-Dibromo-2-hydroxybenzaldehyde. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Quality Control of 90-59-5.

Shool, Maryam Taghizadeh;Rudbari, Hadi Amiri;Gil-Anton, Tania;Cuevas-Vicario, Jose V.;Garcia, Begona;Busto, Natalia;Moini, Nakisa;Blacque, Olivier research published 《 The effect of halogenation of salicylaldehyde on the antiproliferative activities of {Δ/Λ-[Ru(bpy)₂(X,Y-sal)]BF₄} complexes》, the research content is summarized as follows. Ru(II) polypyridyl complexes are widely used in biol. fields, due to their physicochem. and photophys. properties. New chiral Ru(II) polypyridyl complexes (1–5) {Δ/Λ-[Ru(bpy)₂(X,Y-sal)]BF₄} (bpy = 2,2′-bipyridyl; X,Y-sal = 5-bromosalicylaldehyde 1, 3,5-dibromosalicylaldehyde 2, 5-chlorosalicylaldehyde 3, 3,5-dichlorosalicylaldehyde 4 and 3-bromo-5-chlorosalicylaldehyde 5) were synthesized and characterized by elemental anal., FTIR, and ¹H/¹³C NMR spectroscopy. The structures of 1 and 5 were determined by x-ray crystallog. and showed that the central Ru adopts a distorted octahedral coordination sphere with two bpy and one halogen-substituted salicylaldehyde. DFT and TD-DFT calculations were performed to explain the excited states of these complexes. The singlet states with higher oscillator strength are correlated with the absorption signals and are mainly described as ¹MLCT from the Ru center to the bpy ligands. The lowest triplet states (T₁) are described as ³MLCT from the Ru center to the salicylaldehyde ligand. The theor. results are in good agreement with the observed unstructured band at ∼520 nm for complexes 2, 4 and 5. Biol. studies on human cancer cells revealed that dihalogenated ligands endow the Ru(II) complexes with enhanced cytotoxicity compared to monohalogenated ligands. As far as the type of halogen is concerned, Br is the halogen that provides the highest cytotoxicity to the synthesized complexes. All complexes induce cell cycle arrest in G0/G1 and apoptosis, but only complexes bearing Br are able to provoke an increase in intracellular ROS levels and mitochondrial dysfunction.

Quality Control of 90-59-5, 3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Shaik, Mahammad Sadik team published research in Journal of Heterocyclic Chemistry in 2021 | 90-59-5

90-59-5, 3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes.

Shaik, Mahammad Sadik;Nadiveedhi, Maheshwara Reddy;Gundluru, Mohan;Narreddy, Ananda Kumar Reddy;Thathireddy, Krishna Reddy;Ramakrishna, Ranjani;Cirandur, Suresh Reddy research published 《 2-Amino-3-cyano-4H-chromene-4-ylphosphonates as potential antiviral agents: Synthesis, in ovo and in silico approach》, the research content is summarized as follows. A simplistic synthetic procedure for the synthesis of structurally diversified 2-amino-3-cyano-4H-chromene-4-ylphosphonates were developed by the treatment of substituted salicylaldehydes, malononitrile, and dialkyl phosphite in presence of Cu(OAc)₂ catalyst at room temperature and neat conditions. The synthesized compounds were tested for their antiviral assay. Among all, the compounds three have shown good in ovo antiviral activity against New castle disease virus (NDV) at a concentration of 150μg/mL. The remarkable reduction in NDV virus population in embryos treated with title compounds in a dose dependent manner, indicated that the synthesized compounds are extreme by toxic to the NDV virus. The title compounds were also docked against hemagglutinin neuraminidase enzyme and the more bioactive compound showed highest docking score than the standard antiviral drug taribavirin while two compounds have the same docking score as that of the standard

90-59-5, 3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Shaik, Yasmin Haroon team published research in Synthetic Communications in 2022 | 90-59-5

90-59-5, 3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes.

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 90-59-5, formula is C7H4Br2O2, Name is 3,5-Dibromo-2-hydroxybenzaldehyde, Computed Properties of 90-59-5

Shaik, Yasmin Haroon;Chintha, Venkataramaiah;Gundluru, Mohan;Sarva, Santhisudha;Cirandur, Suresh Reddy research published 《 An efficient nano-FGT catalyzed green synthesis of α-aminophosphonates and evaluation of their antioxidant, anti-inflammatory activity and molecular docking studies》, the research content is summarized as follows. A green and efficient one-pot has been developed for the synthesis of a series of new diethyl-(((2,3-dihydrobenzo[b][1,4]dioxin-6yl)amino) (substituted phenyl)methyl) phosphonates (4a–4k) by the Kabachinik-Fields reaction of 2,3-dihydrobenzo[b][1,4]dioxin-6-amine (2a-2k) with various substituted aldehydes (2a–2k) and di-Et phosphite (3) using nano ferrite supported glutathione (nano FGT) as catalyst under microwave irradiation and solvent free conditions. The synthesized compounds were evaluated for their antioxidant (DPPH & FRAP) and anti-inflammatory activity studies. Compounds 4b (naphthyl) and 4k (9-anthracenyl) 4k showed highest antioxidant activity than that of standard ascorbic acid in DPPH method. Whereas compounds 4f (3-nitrophenyl), 4h -phenoxyphenyl and 4k (9-anthracenyl) exhibited low IC₅₀ values than that of standard ascorbic acid in and in Ferric Reducing Antioxidant Power (FRAP) studies. Compounds 4a, 4b, 4h, 4i and 4k have shown strong anti-inflammatory activity against LPS induced cell death in RAW 264.7 cell lines. Mol. docking studies were also carried out against COX-2 showed high binding energies that are in support of their high anti-inflammatory activity. Being the most bioactive compound (4k) stands as promising next future anti-oxidant and anti-inflammatory agent.

90-59-5, 3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Saroya, Sonia team published research in Research on Chemical Intermediates in 2022 | 90-59-5

90-59-5, 3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes.

Saroya, Sonia;Asija, Sonika;Deswal, Yogesh;Kumar, Naresh;Kumar, Ashwani research published 《 Synthesis, spectral studies, in vitro antimicrobial activity and molecular docking studies of organotin(IV) complexes derived from tridentate Schiff base ligands》, the research content is summarized as follows. In this work, diorganotin complexes of Schiff base ligands, R₂SnL I (R = Bu, Me, Ph; R¹, R² = H, CO₂Me; R³, R⁴ = H, Br, OEt), were synthesized. Schiff base ligands were obtained by the condensation of Me 3-amino-4-hydroxybenzoate and Me 4-amino-3-hydroxybenzoate with salicylaldehyde derivatives in equimolar ratio. The structure of all synthesized compounds were confirmed by several spectroscopic techniques like elemental anal., FT-IR, multinuclear (¹H, ¹³C, and ¹¹⁹Sn) NMR and mass spectrometry. From the spectroscopic data, it was found that the Schiff base ligands are coordinated to tin atom through -ONO donor atoms and tin atom exhibits pentacoordinated geometry in all complexes. The synthesized compounds were assessed for their in vitro antimicrobial potential against four bacterial and two fungal strains. Mol. docking studies of the most potent compound 9 was performed with enzyme 3-oxoacyl-[acyl-carrier-protein] synthase 2 (FabF) of Escherichia coli and sterol 14-alpha demethylase of C. albicans to study their interactions.

90-59-5, 3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Satheeshkumar, K. team published research in Inorganic Chemistry Communications in 2022 | 90-59-5

Related Products of 90-59-5, 3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes.

Dehydrobromination, Grignard reactions, reductive coupling, Wittig reaction, and several nucleophilic substitution reactions are some of the principal reactions which involve organic bromides. 90-59-5, formula is C7H4Br2O2, Name is 3,5-Dibromo-2-hydroxybenzaldehyde. Organic compounds having carbon bonded to bromine are called organic bromides. Related Products of 90-59-5.

Satheeshkumar, K.;Saravana Kumar, P.;Shanmugapriya, R.;Nandhini, C.;Vennila, K. N.;Elango, Kuppanagounder P. research published 《 An easy to make Hg(II) complex as a selective and sensitive fluorescent turn-on chemosensor for iodide in an aqueous solution based on metal ion displacement mechanism》, the research content is summarized as follows. A simple Schiff base ligand (L) bearing 3,5-dibromo-2-hyrdoxybenzaldehyde fluorophore moiety has rationally been designed, synthesized and characterized. The Hg(II) complex of L was synthesized by simply stirring a mixture of L and HgCl₂ in ethanol at RT and the resultant non-fluorescent complex HgL is found to detect iodide ion selectively, with a turn-on fluorescence in H₂O:DMSO (1:1 volume/volume) medium. The detection of iodide was performed via the metal ion displacement mechanism with a 1:2 (Probe:Iodide) stoichiometry and binding constant of 1.51 × 10⁴ M^-1. Novel HgL complex showed rapid response towards iodide ion with a limit of detection (LOD) as low as 60 nM. Moreover, the sensing mechanism of iodide by the complex is theor. supported by d. functional theory (DFT) and time dependent d. functional theory (TD-DFT) calculations In addition, estimation of iodide in real water samples, table salt and urine sample demonstrate the practical value of the probe.

Related Products of 90-59-5, 3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Rudbari, Hadi Amiri team published research in Dalton Transactions in 2022 | 90-59-5

Electric Literature of 90-59-5, 3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes.

Rudbari, Hadi Amiri;Saadati, Arezoo;Aryaeifar, Mahnaz;Blacque, Olivier;Correia, Isabel;Islam, Mohammad Khairul;Woschko, Dennis;Janiak, Christoph;Enamullah, Mohammed research published 《 Pseudotetrahedral Zn(II)-(R or S)-dihalogen-salicylaldiminato complexes with Λ- or Δ-chirality induction at-metal》, the research content is summarized as follows. Reactions of enantiopure (S or R)-N-1-(phenyl)ethyl-2,4-X¹,X²-salicylaldimine (S-H or R-H; X¹, X² = dihalogen) with Zn(II)-nitrate give bis[(S or R)-N-1-(phenyl)ethyl-2,4-X¹,X²-salicylaldiminato-κ²N,O]-Zn(II), (Δ-ZnS or Λ-ZnR) with Δ/Λ-chirality induction at-metal in the C₂-sym. mols. EI-mass spectra show parent ion peaks. X-ray structures indicate that two phenolate-O and two imine-N atoms from two mols. of the Schiff bases coordinate to the Zn(II) ion in a pseudotetrahedral geometry. Structural analyses give evidence that the S- or R-ligand chirality gives only one diastereomer Δ-ZnS or Λ-ZnR in an enantiopure crystal. Gas-phase optimized structures suggest that the Δ-ZnS or Λ-ZnR diastereomers are slightly more stable than Λ-ZnS or Δ-ZnR by 1-2 kcal mol^-1. The intramol. interactions were analyzed with the Independent Gradient Model (IGM) using the program Multiwfn on the optimized structures and also indicate the diastereomeric preference of Δ-ZnS1 over Λ-ZnS1 (or Λ-ZnR1 over Δ-ZnR1). Variable time and temperature ¹H NMR spectra support the presence of only one diastereomer Λ-ZnR or Δ-ZnS in the bulk samples, backed by the simulated spectra which exhibit no diastereomerization in solution In contrast, the reported Zn(II)-(R or S)-salicylaldiminato/naphthaldiminato complexes show a diastereomeric mixture of both Δ- and Λ-forms and a Δ ⇄ Λ equilibrium in solution Electronic CD (ECD) spectra in solution display expected mirror-image relations for the (S or R)-Schiff base ligands and the (S or R)-ligated complexes. Combined analyses of exptl. and simulated ECD spectra further support the notion of diastereomeric excess of Δ-ZnS or Λ-ZnR in solution The overall results thus suggest the preservation of chirality at-Zn induced by S- or R-ligands in a solid or solution Supramol. packing analyses explore different kinds of intermol. interactions with the strongest one for X···O. Only the halogen atom in the para position is involved in these interactions with Br···O > Cl···O. Hirshfeld surface analyses also support these interactions between two mols. at a distance shorter than the sum of the van der Wall radii. Comparison of the exptl. and simulated PXRD patterns from the single-crystal x-ray structures shows a good matching and confirms the phase purity of the bulk samples.

Electric Literature of 90-59-5, 3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Rudbari, Hadi Amiri team published research in New Journal of Chemistry in 2022 | 90-59-5

SDS of cas: 90-59-5, 3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes.

Rudbari, Hadi Amiri;Kordestani, Nazanin;Cuevas-Vicario, Jose V.;Zhou, Min;Efferth, Thomas;Correia, Isabel;Schirmeister, Tanja;Barthels, Fabian;Enamullah, Mohammed;Fernandes, Alexandra R.;Micale, Nicola research published 《 Investigation of the influence of chirality and halogen atoms on the anticancer activity of enantiopure palladium(II) complexes derived from chiral amino-alcohol Schiff bases and 2-picolylamine》, the research content is summarized as follows. In continuation of authors work on the synthesis of heteroleptic enantiopure Pd(II)-complexes, four mixed-ligand enantiomeric pairs of Pd(II) complexes (J1–J8), [Pd(pic) (R or S)-N-(2,3-dihydroxypropyl)-3,5-X₁,X₂-salicylaldimines]NO₃, (pic = 2-picolylamine; X₁ = X₂ = Cl, Br, I; X₁/X₂ = Br/Cl), were synthesized by the reaction of enantiopure halogen-substituted Schiff bases (R or S)-N-(2,3-dihydroxypropyl)-3,5-X₁,X₂-salicylaldimines with [Pd(pic)Cl₂] and obtained as yellow precipitates The composition and structure of the complexes were confirmed by elemental analyses, NMR (¹H and ¹³C), FT-IR spectroscopy and theor. calculations The NMR data confirmed the stability of these complexes in DMSO. The electronic structure of the reported complexes was investigated using UV-Vis absorption and electronic CD (ECD) spectroscopy. The antiproliferative activity of the newly synthesized metal complexes was evaluated against CCRF-CEM acute lymphocytic leukemia cells and their multidrug-resistant CEM/ADR5000 subline showing IC₅₀ values in the low-micromolar range. The two most active compounds (J4 and J6) in the assays above were selected for further biol. testing, i.e. cell cycle analyses, apoptosis detection and ability to inhibit the chymotrypsin-like activity of the 20S human proteasome. Both compounds arrested the G2/M cell cycle phase in a concentration-dependent manner without inducing significant apoptosis and inhibited the above-mentioned proteolytic activity of the proteasome in the low-micromolar range.

SDS of cas: 90-59-5, 3,5-Dibromosalicylaldehyde reacts with alkyl cyanoacetates in the presence of ammonium acetate to yield 4H- chromenes.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary