Efficient and Complementary Methods Offering Access to Synthetically Valuable 1,2-Dibromobenzenes was written by Diemer, Vincent;Leroux, Frederic R.;Colobert, Francoise. And the article was included in European Journal of Organic Chemistry in 2011.Formula: C7H7Br2N The following contents are mentioned in the article:
1,2-Dibromobenzenes are highly valuable precursors for various organic transformations, in particular, reactions based on the intermediate formation of benzynes. This report describes short sequences for the synthesis of various derivatives based on regioselective bromination, ortho-metalation, and halogen/metal permutations. 1,2-Dibromo-3-iodobenzene, 1,2-dibromo-4-iodobenzene, and 2,3-dibromo-1,4-diiodobenzene act as intermediates in these syntheses. This study involved multiple reactions and reactants, such as 3,4-Dibromo-2-methylaniline (cas: 858843-50-2Formula: C7H7Br2N).
3,4-Dibromo-2-methylaniline (cas: 858843-50-2) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. Many of the alkyl bromine derivatives are excellent alkylating agents since bromides are good leaving groups. Tribromides, like tetrabutylammonium tribromide, are used as a solid source of bromine. N-bromosuccimide (NBS) is used for the selective bromination of allylic bonds.Formula: C7H7Br2N
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary