Category: 823-78-9

Organic compounds having carbon bonded to bromine are called organic bromides. 823-78-9, formula is C7H6Br2, Name is 1-Bromo-3-(bromomethyl)benzene. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Application In Synthesis of 823-78-9.

Yang, Ren-Yin;Gao, Xinyan;Gong, Kehao;Wang, Juan;Zeng, Xiaojun;Wang, Mingwei;Han, Junbin;Xu, Bo research published 《 Synthesis of ArCF₂X and [¹⁸F]Ar-CF₃ via Cleavage of the Trifluoromethylsulfonyl Group》, the research content is summarized as follows. A versatile synthesis of ArCF₂X and [¹⁸F]Ar-CF₃ type compounds from readily available ArCF₂SO₂CF₃ has been developed. Diverse nucleophiles, including weak nucleophiles such as halides (¹⁸F^–, Cl^–, Br^–, and I^–), RSH, and ROH, could react with ArCF₂SO₂CF₃ efficiently to give the corresponding difluoromethylene products. The control experiments and the Hammett plot indicated that the reaction might proceed through a difluorocarbocation intermediate generated from the steric hindrance-assisted cleavage of the trifluoromethylsulfonyl group.

Application In Synthesis of 823-78-9, 3-Bromobenzyl bromide undergoes reduction with diethylzinc in the presence of Pd(PPh3)4 to yield corresponding hydrocarbon.

3-Bromobenzyl bromide is a useful research compound. Its molecular formula is C7H6Br2 and its molecular weight is 249.93 g/mol. The purity is usually 95%.

3-Bromobenzyl bromide is a molecule that has been synthesized and shown to have anticancer activity. It inhibits the activity of cancer cells by binding to amines in these cells and preventing the formation of hydrogen bonds between these molecules. 3-Bromobenzyl bromide has also been shown to selectively inhibit the activity of NS5B polymerase, an enzyme that is important in the replication of the hepatitis C virus. The synthetic nature of this molecule makes it an attractive target for analytical methods such as nuclear magnetic resonance spectroscopy. This molecule also shows significant cytotoxicity against cancer cell lines in vitro, as well as inducing tumor necrosis factor-alpha (TNF-α) production in lps-stimulated murine macrophages., 823-78-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic compounds having carbon bonded to bromine are called organic bromides. 823-78-9, formula is C7H6Br2, Name is 1-Bromo-3-(bromomethyl)benzene. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. COA of Formula: C7H6Br2.

Yan, Qiuli;Cui, Wenwen;Li, Junxin;Xu, Guiyun;Song, Xiuyan;Lv, Jian;Yang, Daoshan research published 《 C-H benzylation of quinoxalin-2(1H)-ones via visible-light riboflavin photocatalysis》, the research content is summarized as follows. An efficient visible-light promoted riboflavin-catalyzed direct benzylation of substituted quinoxalin-2(1H)-ones for the synthesis of various C3-benzylated quinoxalin-2(1H)-one derivatives was developed under mild conditions. The present method used readily available benzyl bromides as alkylating reagents and environmentally friendly and inexpensive riboflavin (vitamin B₂) as a green organic photocatalyst. This method opened a new avenue towards C3-benzylated quinoxalin-2(1H)-ones, thus promised their broad applications in pharmaceutical chem. and synthetic chem.

COA of Formula: C7H6Br2, 3-Bromobenzyl bromide undergoes reduction with diethylzinc in the presence of Pd(PPh3)4 to yield corresponding hydrocarbon.

3-Bromobenzyl bromide is a useful research compound. Its molecular formula is C7H6Br2 and its molecular weight is 249.93 g/mol. The purity is usually 95%.

3-Bromobenzyl bromide is a molecule that has been synthesized and shown to have anticancer activity. It inhibits the activity of cancer cells by binding to amines in these cells and preventing the formation of hydrogen bonds between these molecules. 3-Bromobenzyl bromide has also been shown to selectively inhibit the activity of NS5B polymerase, an enzyme that is important in the replication of the hepatitis C virus. The synthetic nature of this molecule makes it an attractive target for analytical methods such as nuclear magnetic resonance spectroscopy. This molecule also shows significant cytotoxicity against cancer cell lines in vitro, as well as inducing tumor necrosis factor-alpha (TNF-α) production in lps-stimulated murine macrophages., 823-78-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic compounds having carbon bonded to bromine are called organic bromides. 823-78-9, formula is C7H6Br2, Name is 1-Bromo-3-(bromomethyl)benzene. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Quality Control of 823-78-9.

Yadav, Suman;Chaudhary, Dhananjay;Maurya, Naveen Kumar;Kumar, Dharmendra;Ishu, Km;Kuram, Malleswara Rao research published 《 Transfer hydrogenation of pyridinium and quinolinium species using ethanol as a hydrogen source to access saturated N-heterocycles》, the research content is summarized as follows. Reported a TH protocol that utilized ethanol as a renewable hydrogen source and an Ir catalyst for the reduction of quinolines and pyridines. The reaction was promoted by simple amides as ligands.

823-78-9, 3-Bromobenzyl bromide undergoes reduction with diethylzinc in the presence of Pd(PPh3)4 to yield corresponding hydrocarbon.

3-Bromobenzyl bromide is a useful research compound. Its molecular formula is C7H6Br2 and its molecular weight is 249.93 g/mol. The purity is usually 95%.

3-Bromobenzyl bromide is a molecule that has been synthesized and shown to have anticancer activity. It inhibits the activity of cancer cells by binding to amines in these cells and preventing the formation of hydrogen bonds between these molecules. 3-Bromobenzyl bromide has also been shown to selectively inhibit the activity of NS5B polymerase, an enzyme that is important in the replication of the hepatitis C virus. The synthetic nature of this molecule makes it an attractive target for analytical methods such as nuclear magnetic resonance spectroscopy. This molecule also shows significant cytotoxicity against cancer cell lines in vitro, as well as inducing tumor necrosis factor-alpha (TNF-α) production in lps-stimulated murine macrophages., Quality Control of 823-78-9

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Vinyl bromides undergo the Heck reaction, which involves C-C coupling with alkene to give substituted alkenes. 823-78-9, formula is C7H6Br2, Name is 1-Bromo-3-(bromomethyl)benzene. Methyl bromide is a precursor in the manufacture of several chemicals and is employed as a soil sterilant, mainly for seed production. Synthetic Route of 823-78-9.

Yagiz, Guler;Noma, Samir Abbas Ali;Altundas, Aliye;Al-khafaji, Khattab;Taskin-Tok, Tugba;Ates, Burhan research published 《 Synthesis, inhibition properties against xanthine oxidase and molecular docking studies of dimethyl N-benzyl-1H-1,2,3-triazole-4,5-dicarboxylate and (N-benzyl-1H-1,2,3-triazole-4,5-diyl)dimethanol derivatives》, the research content is summarized as follows. This study was focused on synthesis of various di-Me N-benzyl-1H-1,2,3-triazole-4,5-dicarboxylate and (N-benzyl-1H-1,2,3-triazole-4,5-diyl)dimethanol derivatives I (R = methoxycarbonyl, hydroxymethyl; X = 2-OH, 3-Br, 4-OMe, 2-OH-5-Cl, etc.) under the conditions of green chem. without the use of solvent and catalysts. Their inhibition properties were also investigated on xanthine oxidase (XO) activity. All dimethanol and dicarboxylate derivatives I exhibited significant inhibition activities with IC₅₀ values ranging from 0.71 to 2.25μM. Especially, I [R = hydroxymethyl, X = 3-Br; and R = methoxycarbonyl, X = 4-Cl] compounds were found to be the most promising derivatives on the XO enzyme inhibition with IC₅₀ values 0.71 and 0.73μM, resp. Moreover, the double docking procedure was used to evaluate compound modes of inhibition and their interactions with the protein (XO) at at. level. Surprisingly, the docking results showed a good correlation with IC₅₀ [correlation coefficient (R² = 0.7455)]. Also, the docking results exhibited that the I [R = hydroxymethyl, X = 3-Br; R = methoxycarbonyl, X = 4-OH; and R = methoxycarbonyl, X = 4-Cl] have lowest docking scores -4.790, -4.755, and -4.730, resp. These data were in agreement with the IC₅₀ values. These results give promising beginning stages to assist in the improvement of novel and powerful inhibitor against XO.

823-78-9, 3-Bromobenzyl bromide undergoes reduction with diethylzinc in the presence of Pd(PPh3)4 to yield corresponding hydrocarbon.

3-Bromobenzyl bromide is a useful research compound. Its molecular formula is C7H6Br2 and its molecular weight is 249.93 g/mol. The purity is usually 95%.

3-Bromobenzyl bromide is a molecule that has been synthesized and shown to have anticancer activity. It inhibits the activity of cancer cells by binding to amines in these cells and preventing the formation of hydrogen bonds between these molecules. 3-Bromobenzyl bromide has also been shown to selectively inhibit the activity of NS5B polymerase, an enzyme that is important in the replication of the hepatitis C virus. The synthetic nature of this molecule makes it an attractive target for analytical methods such as nuclear magnetic resonance spectroscopy. This molecule also shows significant cytotoxicity against cancer cell lines in vitro, as well as inducing tumor necrosis factor-alpha (TNF-α) production in lps-stimulated murine macrophages., Synthetic Route of 823-78-9

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic compounds having carbon bonded to bromine are called organic bromides. 823-78-9, formula is C7H6Br2, Name is 1-Bromo-3-(bromomethyl)benzene. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Recommanded Product: 1-Bromo-3-(bromomethyl)benzene.

Xu, Ming-Hui;Yuan, Yong-Hai;Liang, Dong-Dong;Zhang, Xiao-Ming;Zhang, Fu-Min;Tu, Yong-Qiang;Ma, Ai-Jun;Zhang, Kun;Peng, Jin-Bao research published 《 Remote asymmetric conjugate addition catalyzed by a bifunctional spiro-pyrrolidine-derived thiourea catalyst》, the research content is summarized as follows. A novel spiro-pyrrolidine (SPD)-derived bifunctional thiourea catalyst has been developed, enabling the development of a stereoselective conjugate addition of furfurals to β,γ-unsaturated α-ketoesters. The reaction represents an example of asym. trienamine catalysis in the benzylic C-H functionalization of 5-benzylfurfurals, and the rigid spirocyclic framework of the catalyst is proven to be essential for a highly enantioselective transformation.

823-78-9, 3-Bromobenzyl bromide undergoes reduction with diethylzinc in the presence of Pd(PPh3)4 to yield corresponding hydrocarbon.

3-Bromobenzyl bromide is a useful research compound. Its molecular formula is C7H6Br2 and its molecular weight is 249.93 g/mol. The purity is usually 95%.

3-Bromobenzyl bromide is a molecule that has been synthesized and shown to have anticancer activity. It inhibits the activity of cancer cells by binding to amines in these cells and preventing the formation of hydrogen bonds between these molecules. 3-Bromobenzyl bromide has also been shown to selectively inhibit the activity of NS5B polymerase, an enzyme that is important in the replication of the hepatitis C virus. The synthetic nature of this molecule makes it an attractive target for analytical methods such as nuclear magnetic resonance spectroscopy. This molecule also shows significant cytotoxicity against cancer cell lines in vitro, as well as inducing tumor necrosis factor-alpha (TNF-α) production in lps-stimulated murine macrophages., Recommanded Product: 1-Bromo-3-(bromomethyl)benzene

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic compounds having carbon bonded to bromine are called organic bromides. 823-78-9, formula is C7H6Br2, Name is 1-Bromo-3-(bromomethyl)benzene. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. COA of Formula: C7H6Br2.

Wu, Tianxiao;Zhang, Chu;Lv, Ruicheng;Qin, Qiaohua;Liu, Nian;Yin, Wenbo;Wang, Ruifeng;Sun, Yin;Wang, Xiaoyan;Sun, Yixiang;Zhao, Dongmei;Cheng, Maosheng research published 《 Design, synthesis, biological evaluation and pharmacophore model analysis of novel tetrahydropyrrolo[3,4-c]pyrazol derivatives as potential TRKs inhibitors》, the research content is summarized as follows. Synthesis, biol. evaluation and pharmacophore model anal. of novel tetrahydropyrrolo[3,4-c]pyrazol derivatives I [Ar¹ = Ph, 2-FC₆H₄, 3-ClC₆H₄, etc.] and II [R¹ = H, F; R² = H, F; Ar² = 4-FC₆H₄, 2-naphthyl, 4-morpholinophenyl, etc.] as potential TRKs inhibitors were obtained using scaffold hopping strategy. Compound II [R¹ = H; R² = F; Ar² = 4-(4-methylpiperazin-1-yl)-phenyl] significantly inhibited the proliferation of TRK-dependent cell lines (Km-12), while it had no inhibitory effect on TRK-independent cell lines (A549 and THLE-2). Furthermore, kinases selectivity profiling showed that in addition to TRKs, compound II [R¹ = H; R² = F; Ar² = 4-(4-methylpiperazin-1-yl)-phenyl] only displayed relatively strong inhibitory activity on ALK. These data might indicated that compound II [R¹ = H; R² = F; Ar² = 4-(4-methylpiperazin-1-yl)-phenyl] had a good drug safety. Partial ADME properties were evaluated in vitro and in vivo and compound II [R¹ = H; R² = F; Ar² = 4-(4-methylpiperazin-1-yl)-phenyl] exhibited a good AUC values and volume of distribution and low clearance in the pharmacokinetics experiment of rats.

COA of Formula: C7H6Br2, 3-Bromobenzyl bromide undergoes reduction with diethylzinc in the presence of Pd(PPh3)4 to yield corresponding hydrocarbon.

3-Bromobenzyl bromide is a useful research compound. Its molecular formula is C7H6Br2 and its molecular weight is 249.93 g/mol. The purity is usually 95%.

3-Bromobenzyl bromide is a molecule that has been synthesized and shown to have anticancer activity. It inhibits the activity of cancer cells by binding to amines in these cells and preventing the formation of hydrogen bonds between these molecules. 3-Bromobenzyl bromide has also been shown to selectively inhibit the activity of NS5B polymerase, an enzyme that is important in the replication of the hepatitis C virus. The synthetic nature of this molecule makes it an attractive target for analytical methods such as nuclear magnetic resonance spectroscopy. This molecule also shows significant cytotoxicity against cancer cell lines in vitro, as well as inducing tumor necrosis factor-alpha (TNF-α) production in lps-stimulated murine macrophages., 823-78-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 823-78-9, formula is C7H6Br2, Name is 1-Bromo-3-(bromomethyl)benzene. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Category: bromides-buliding-blocks.

Xiang, Panjie;Sun, Kai;Wang, Shuang;Chen, Xiaolan;Qu, Lingbo;Yu, Bing research published 《 Direct benzylation reactions from benzyl halides enabled by transition-metal-free photocatalysis》, the research content is summarized as follows. An SN²-based photochem. strategy using dithiocarbamate anion as catalyst was developed for the activation of benzyl halides, which are extremely challenging to be applied as radical precursors in visible light photocatalysis. With this transition-metal-free and oxidant-free protocol, the benzylation (or cyanomethylation) of various heterocycles including quinoxalin-2(1H)-ones, coumarin, 2-phenyl-2H-indazole, 1-methyl-5-phenylpyrazin-2(1H)-one, 1-(fluoromethyl)cinnolin-4(1H)-one, and 2,4-dibenzyl-1,2,4-triazine-3,5(2H,4H)-dione could be realized (46 examples, up to 98% yield). Importantly, some biol. relevant 3-benzylquinoxalin-2(1H)-ones were also be synthesized under mild conditions.

Category: bromides-buliding-blocks, 3-Bromobenzyl bromide undergoes reduction with diethylzinc in the presence of Pd(PPh3)4 to yield corresponding hydrocarbon.

3-Bromobenzyl bromide is a useful research compound. Its molecular formula is C7H6Br2 and its molecular weight is 249.93 g/mol. The purity is usually 95%.

3-Bromobenzyl bromide is a molecule that has been synthesized and shown to have anticancer activity. It inhibits the activity of cancer cells by binding to amines in these cells and preventing the formation of hydrogen bonds between these molecules. 3-Bromobenzyl bromide has also been shown to selectively inhibit the activity of NS5B polymerase, an enzyme that is important in the replication of the hepatitis C virus. The synthetic nature of this molecule makes it an attractive target for analytical methods such as nuclear magnetic resonance spectroscopy. This molecule also shows significant cytotoxicity against cancer cell lines in vitro, as well as inducing tumor necrosis factor-alpha (TNF-α) production in lps-stimulated murine macrophages., 823-78-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 823-78-9, formula is C7H6Br2, Name is 1-Bromo-3-(bromomethyl)benzene. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Application In Synthesis of 823-78-9.

Wu, Gaorong;Yang, Zhaoziyuan;Xu, Xiaobo;Hao, Liqiang;Chen, Lu;Wang, Yangyang;Ji, Yafei research published 《 Metal-Free Boron-Mediated ortho-C-H Hydroxylation of N-Benzyl-3,4,5-tribromopyrazoles》, the research content is summarized as follows. A novel route was reported for C-H hydroxylation of benzyl compounds directed by a 3,4,5-tribromopyrazole auxiliary via boronation/oxidation using BBr₃ and NaBO₃·4H₂O. The strategy exhibited outstanding site selectivity and afforded the corresponding phenols in moderate to excellent yields under metal-free conditions. Besides, this protocol was achieved in one pot, which is highly promising as a practical method for use in a multistep organic synthetic process.

Application In Synthesis of 823-78-9, 3-Bromobenzyl bromide undergoes reduction with diethylzinc in the presence of Pd(PPh3)4 to yield corresponding hydrocarbon.

3-Bromobenzyl bromide is a useful research compound. Its molecular formula is C7H6Br2 and its molecular weight is 249.93 g/mol. The purity is usually 95%.

3-Bromobenzyl bromide is a molecule that has been synthesized and shown to have anticancer activity. It inhibits the activity of cancer cells by binding to amines in these cells and preventing the formation of hydrogen bonds between these molecules. 3-Bromobenzyl bromide has also been shown to selectively inhibit the activity of NS5B polymerase, an enzyme that is important in the replication of the hepatitis C virus. The synthetic nature of this molecule makes it an attractive target for analytical methods such as nuclear magnetic resonance spectroscopy. This molecule also shows significant cytotoxicity against cancer cell lines in vitro, as well as inducing tumor necrosis factor-alpha (TNF-α) production in lps-stimulated murine macrophages., 823-78-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 823-78-9, formula is C7H6Br2, Name is 1-Bromo-3-(bromomethyl)benzene. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Name: 1-Bromo-3-(bromomethyl)benzene.

Wu, Meng-Ke;Man, Ruo-Jun;Liao, Yan-Juan;Zhu, Hai-Liang;Zhou, Zhu-Gui research published 《 Discovery of novel indole-1,2,4-triazole derivatives as tubulin polymerization inhibitors》, the research content is summarized as follows. A series of novel indole-1,2,4-triazole derivatives have been designed, synthesized, and evaluated as potential tubulin polymerization inhibitors. The top hit 12, bearing the 3,4,5-trimethoxyphenyl moiety, exhibited substantial anti-proliferative activity against HepG2, HeLa, MCF-7, and A549 cells in vitro with IC₅₀ values of 0.23 ± 0.08μM, 0.15 ± 0.18μM, 0.38 ± 0.12μM, and 0.30 ± 0.13μM, resp. It also inhibited tubulin polymerization with the IC₅₀ value of 2.1 ± 0.12μM, which was comparable with that of the pos. controls. Furthermore, compound 12 regulated the expression of cell cycle-related proteins (Cyclin B1, Cdc25c, and Cdc2) and apoptosis-related proteins (Bcl-2, Bcl-x, and Mcl-1). Mechanistically, compound 12 could arrest cell cycle at the G2/M phase, thus induce an increase of apoptotic cell death. In addition, mol. docking hinted the possible interaction mode of compound 12 into the colchicine binding site of tubulin heterodimers. According to the applications of microtubule-targeting agents in both direct and synergistic cancer therapies, we hope this work might be of significance for future researches.

823-78-9, 3-Bromobenzyl bromide undergoes reduction with diethylzinc in the presence of Pd(PPh3)4 to yield corresponding hydrocarbon.

3-Bromobenzyl bromide is a useful research compound. Its molecular formula is C7H6Br2 and its molecular weight is 249.93 g/mol. The purity is usually 95%.

3-Bromobenzyl bromide is a molecule that has been synthesized and shown to have anticancer activity. It inhibits the activity of cancer cells by binding to amines in these cells and preventing the formation of hydrogen bonds between these molecules. 3-Bromobenzyl bromide has also been shown to selectively inhibit the activity of NS5B polymerase, an enzyme that is important in the replication of the hepatitis C virus. The synthetic nature of this molecule makes it an attractive target for analytical methods such as nuclear magnetic resonance spectroscopy. This molecule also shows significant cytotoxicity against cancer cell lines in vitro, as well as inducing tumor necrosis factor-alpha (TNF-α) production in lps-stimulated murine macrophages., Name: 1-Bromo-3-(bromomethyl)benzene

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 823-78-9, formula is C7H6Br2, Name is 1-Bromo-3-(bromomethyl)benzene. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Name: 1-Bromo-3-(bromomethyl)benzene.

Wang, Zhuangzhuang;Zhou, Xuehao;Gong, Shaofeng;Xie, Jianwei research published 《 MOF-Derived Cu@N-C Catalyst for 1,3-Dipolar Cycloaddition Reaction》, the research content is summarized as follows. Cu(i.m.)₂-derived Cu-N-C composites were used for the first time as efficient heterogeneous catalysts for one-pot 1,3-dipolar cycloaddition of terminal alkynes, aryl halides, and sodium azide to preparation of 1,4-disubstituted 1,2,3-triazoles with broad substrate scope and high yields. The catalyst can be easily reused without the changes of structure and morphol., and the heterogeneity nature was confirmed from the catalyst recyclability and metal leaching test.

Name: 1-Bromo-3-(bromomethyl)benzene, 3-Bromobenzyl bromide undergoes reduction with diethylzinc in the presence of Pd(PPh3)4 to yield corresponding hydrocarbon.

3-Bromobenzyl bromide is a useful research compound. Its molecular formula is C7H6Br2 and its molecular weight is 249.93 g/mol. The purity is usually 95%.

3-Bromobenzyl bromide is a molecule that has been synthesized and shown to have anticancer activity. It inhibits the activity of cancer cells by binding to amines in these cells and preventing the formation of hydrogen bonds between these molecules. 3-Bromobenzyl bromide has also been shown to selectively inhibit the activity of NS5B polymerase, an enzyme that is important in the replication of the hepatitis C virus. The synthetic nature of this molecule makes it an attractive target for analytical methods such as nuclear magnetic resonance spectroscopy. This molecule also shows significant cytotoxicity against cancer cell lines in vitro, as well as inducing tumor necrosis factor-alpha (TNF-α) production in lps-stimulated murine macrophages., 823-78-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary