Efficient synthetic method for the preparation of allyl- and propargyl-epoxides by allylation and propargylation of α-haloketones with organozinc reagents was written by Pan, Jie;Zhang, Min;Zhang, Songlin. And the article was included in Organic & Biomolecular Chemistry in 2012.Safety of 2-Bromo-1-(pyren-1-yl)ethanone The following contents are mentioned in the article:
A simple, efficient, and non-metal catalyzed synthetic method for the preparation of substituted allyl- and propargylepoxides by allylation and propargylation of α-halo ketones with organozinc reagents in mild conditions is reported in this paper. The present method complements the existing synthetic methods due to some advantageous properties of the organozinc reagents such as availability, selectivity, operational simplicity and low toxicity. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Safety of 2-Bromo-1-(pyren-1-yl)ethanone).
2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine.Safety of 2-Bromo-1-(pyren-1-yl)ethanone
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary