Category: 74386-13-3

Faury, Thomas published the artcileSide functionalization of diboronic acid precursors for covalent organic frameworks, Application In Synthesis of 74386-13-3, the main research area is side functionalized benzenediboronate preparation precursor covalent organic framework.

Substituted 1,4-benzenediboronic acids (BDBA) were synthesized and their thermal properties studied. Two diboronic acids were studied as building-blocks for covalent organic framework (COF) formation, 2,5-dimethoxy-1,4-benzenediboronic acid and 2-nitro-1,4-benzeneboronic acid. Substitution of the BDBA core caused a dramatic decrease of the polymerization temperature giving a less organized structure.

CrystEngComm published new progress about Annealing. 74386-13-3 belongs to class bromides-buliding-blocks, name is 4-Bromo-3-nitrophenylboronic acid, and the molecular formula is C6H5BBrNO4, Application In Synthesis of 74386-13-3.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Bektenova, G. A. published the artcileIonization constants of boronic acids and their complexation with diols, Related Products of bromides-buliding-blocks, the main research area is boronic acid ionization constant complexation diol.

Ionization constants of a number of boronic acids were determined spectrophotometrically in aqueous solutions The effect of different substituents on their acid properties is considered. The strongest acids are shown to be phenylboronic acid derivatives containing a nitro group. A model study of the interaction between boronic acids and polyvinyl alc. depending on pH is analyzed to reveal the optimum conditions for the formation of a stable boronate-diol complex.

Russian Journal of Physical Chemistry A published new progress about Absorptivity. 74386-13-3 belongs to class bromides-buliding-blocks, name is 4-Bromo-3-nitrophenylboronic acid, and the molecular formula is C6H5BBrNO4, Related Products of bromides-buliding-blocks.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Garner, Charles W. published the artcileSerum cholinesterase inhibition by boronic acids, SDS of cas: 74386-13-3, the main research area is serum cholinesterase inhibition boronic acid; active site cholinesterase boronic acid.

Horse serum cholinesterase (EC 3.1.1.8) was reversibly inhibited by a variety of alkyl- and areneboronic acids with Ki values ranging from 6.2 mM (methaneboronic acid) to 3.1 μM (diphenylboric acid). Binding to the enzyme was apparently at the active center, because inhibition obeyed competitive kinetics and because boronic acids protected the enzyme from inactivation by phenylmethanesulfonyl fluoride. Boronic acids should prove useful in probing the active center of serum cholinesterase.

Biochimica et Biophysica Acta, Protein Structure and Molecular Enzymology published new progress about Blood serum. 74386-13-3 belongs to class bromides-buliding-blocks, name is 4-Bromo-3-nitrophenylboronic acid, and the molecular formula is C6H5BBrNO4, SDS of cas: 74386-13-3.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Garner, Charles W. published the artcileBoronic acid inhibitors of porcine pancreatic lipase, Computed Properties of 74386-13-3, the main research area is lipase pancreas inhibition boronic acid.

Porcine pancreatic lipase was inhibited by alkane and arene boronic acids. The inhibition by octadecane boronic acid was competitive when measured against the hydrolysis of dissolved tripropionin in the presence of siliconized glass beads. The value of Ki in this system was 1.34 × 103 mols. μm-2. The ratio of substrate to inhibitor concentrations giving 50% inhibition was in the range 700-2200, indicating that lipase has a greater affinity for boronic acids than for tripropionin. Boronic acids did not interfere with the interaction of lipase with the siliconized glass/water interface, demonstrating that the binding of lipase to substrate interfaces, the 1st step in lipase action, was not the step at which inhibition occurred. The boronic acid binding site on lipase is at or near the active center serine since modification of this residue by di-Et p-nitrophenyl phosphate was prevented by boronic acids. Modification of the active center serine residue by di-Et p-nitrophenyl phosphate also prevented boronic acid binding. Binding of a chromophoric boronic acid, 7-nitrobenzo-2-oxa-1,3-diazolyl m-aminobenzene boronic acid, to lipase was demonstrated by equilibrium gel filtration on polyacrylamide beads (Bio-Gel P-60) in the presence of 4 mM Na taurodeoxycholate. The complex contained 1 mol. of boronic acid/mol. of lipase and had a dissociation constant of 5 × 10-6 M. The boronic acid was not bound in the absence of taurodeoxycholate. Boronic acids are apparently analogs of the tetrahedral intermediate in the action of lipase.

Journal of Biological Chemistry published new progress about Enzyme kinetics. 74386-13-3 belongs to class bromides-buliding-blocks, name is 4-Bromo-3-nitrophenylboronic acid, and the molecular formula is C6H5BBrNO4, Computed Properties of 74386-13-3.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary