Category: 7051-34-5

Bao, Xin; Wang, Chunhong; Zhang, Zhenyu; Cao, Qinghua; Liu, Fei; Chen, Jing; Zhang, Chuanzhi; Na, Haining; Zhu, Jin published their research in Carbohydrate Polymer Technologies and Applications in 2021. The article was titled 《Wet spinning to prepare filaments from three cellulose carbonated derivatives: Synthesis, characterization and filament properties》.SDS of cas: 7051-34-5 The article contains the following contents:

In this article, three kinds of cellulose carbonated derivatives are synthesized by modifying cellulose with alkyl halides (namely bromopropane, benzyl bromide and bromomethyl cyclopropane) in DBU/DMSO/CO2 system. The wet spinnability and filament properties of the obtained cellulose carbonated derivatives are investigated. Through rheol. anal., the solutions of various cellulose carbonated derivative in Newtonian fluid state can show good wet spinnability. Filaments with smooth surface and uniform morphol. can be obtained from the solution with viscosity over 0.07Pa•s. The cellulose carbonated derivatives in the filament show similar in tight orderly rows. Among them, the cellulose Pr carbonated derivative filament exhibits the highest mech. properties and heat resistance. By using of DBU/DMSO/CO2 system, the wet spinning and key control condition of cellulose carbonated derivatives are combined to achieve for the formation of filament with uniform morphol. In the experimental materials used by the author, we found (Bromomethyl)cyclopropane(cas: 7051-34-5SDS of cas: 7051-34-5)

(Bromomethyl)cyclopropane(cas: 7051-34-5) is used as a synthetic building block for the introduction of the cyclopropylmethyl group. It was also used in the synthesis of 1,4-dienes via iron-catalyzed cross-coupling with alkenyl Grignard reagents.SDS of cas: 7051-34-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2019,Chemical Communications (Cambridge, United Kingdom) included an article by Liu, Lin; Lei, Lin-Sheng; Zhan, Zong-Song; Liu, Si-Zhan; Wang, Yu-Xiao; Tu, Yong-Qiang; Zhang, Fu-Min; Zhang, Xiao-Ming; Ma, Ai-Jun; Wang, Shao-Hua. Category: bromides-buliding-blocks. The article was titled 《A catalytic asymmetric one-pot [3+2] cyclization/semipinacol rearrangement sequence: an efficient construction of a multi-substituted 3H-spiro[benzofuran-2,1′-cyclopentane] skeleton》. The information in the text is summarized as follows:

A facile and efficient method to form a chiral multi-substituted 3H-spiro[benzofuran-2,1′-cyclopentane] structural unit was developed via a one-pot [3+2] cycloaddition/semipinacol rearrangement cascade. A catalysis system of Cu(II)/BOX was used to efficiently construct a key stereogenic center via a cyclization between substituted benzoquinones and allylic alcs. afforded the desired products in good yields and with excellent enantioselectivities and diastereoselectivities (21 examples; up to 67% yields; up to 92% ee and up to >20 : 1 dr). This method provided an alternative strategy for the synthesis of the corresponding bioactive mols. containing spiro[benzofurancyclopentane] skeleton units. In the experimental materials used by the author, we found (Bromomethyl)cyclopropane(cas: 7051-34-5Category: bromides-buliding-blocks)

(Bromomethyl)cyclopropane(cas: 7051-34-5) is used as a synthetic building block for the introduction of the cyclopropylmethyl group. It was also used in the synthesis of 1,4-dienes via iron-catalyzed cross-coupling with alkenyl Grignard reagents.Category: bromides-buliding-blocks

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2019,Chemical Communications (Cambridge, United Kingdom) included an article by Guo, Lei; Xu, Chen; Wu, Ding-Chuan; Hu, Guang-Qi; Zhang, Hong-Hai; Hong, Kunlun; Chen, Su; Liu, Xiang. Recommanded Product: (Bromomethyl)cyclopropane. The article was titled 《Cascade alkylation and deuteration with aryl iodides via Pd/norbornene catalysis: an efficient method for the synthesis of congested deuterium-labeled arenes》. The information in the text is summarized as follows:

An efficient approach for the synthesis of congested deuterium-labeled arenes, e.g., I via cascade alkylation and deuteration with aryl iodides was disclosed. The adoption of sodium formate-d as a deuterium source was the key for achieving high deuterium incorporation >98%. In the experiment, the researchers used many compounds, for example, (Bromomethyl)cyclopropane(cas: 7051-34-5Recommanded Product: (Bromomethyl)cyclopropane)

(Bromomethyl)cyclopropane(cas: 7051-34-5) is used as a synthetic building block for the introduction of the cyclopropylmethyl group. It was also used in the synthesis of 1,4-dienes via iron-catalyzed cross-coupling with alkenyl Grignard reagents.Recommanded Product: (Bromomethyl)cyclopropane

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2022,Patel, Kaushalendra; Lanke, Veeranjaneyulu; Marek, Ilan published an article in Journal of the American Chemical Society. The title of the article was 《Stereospecific Construction of Quaternary Carbon Stereocenters from Quaternary Carbon Stereocenters》.Application of 7051-34-5 The author mentioned the following in the article:

Organoaluminum species promote a smooth nucleophilic substitution at quaternary C stereocenter of stereodefined polysubstituted cyclopropyl Me phosphate with a complete inversion of configuration, even when more reactive functional groups are present. The regio- and diastereoselectivity of the substitution is attributed to the existence of a bicyclobutonium intermediate. In the experimental materials used by the author, we found (Bromomethyl)cyclopropane(cas: 7051-34-5Application of 7051-34-5)

(Bromomethyl)cyclopropane(cas: 7051-34-5) is used as a synthetic building block for the introduction of the cyclopropylmethyl group. It was also used in the synthesis of 1,4-dienes via iron-catalyzed cross-coupling with alkenyl Grignard reagents.Application of 7051-34-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2022,Rodrigalvarez, Jesus; Reeve, Luke A.; Miro, Javier; Gaunt, Matthew J. published an article in Journal of the American Chemical Society. The title of the article was 《Pd(II)-Catalyzed Enantioselective C(sp3)-H Arylation of Cyclopropanes and Cyclobutanes Guided by Tertiary Alkylamines》.Formula: C4H7Br The author mentioned the following in the article:

Here, a palladium-catalyzed enantioselective C(sp3)-H arylation of aminomethyl-cyclopropanes I [R = H, Me, (CH2)2OMe, 4-ClC6H44; R1 = NMe2, NEt2, N-piperidinyl, etc.; Ar = Ph, 2-naphthyl, 6-Cl-3-pyridinyl, etc.; n = 1] and -cyclobutanes I [n = 2] with aryl boronic acids was reported. A range of native tertiary alkylamine groups were able to direct C-H cleavage and forge carbon-aryl bonds on the strained cycloalkanes framework as single diastereomers and with excellent enantiomeric ratios. Central to the success of this strategy was the use of a simple N-acetyl amino acid ligand, which not only controls the enantioselectivity but also promotes γ-C-H activation of over other pathways. Computational anal. of the cyclopalladation step provided an understanding of how enantioselective C-H cleavage occurred and revealed distinct transition structures to our previous work on enantioselective desymmetrization of N-iso-Bu tertiary alkylamines. This straightforward and operationally simple method simplified the construction of functionalized aminomethyl-strained cycloalkanes, which was believed will find widespread use in academic and industrial settings relating to the synthesis of biol. active small mols.(Bromomethyl)cyclopropane(cas: 7051-34-5Formula: C4H7Br) was used in this study.

(Bromomethyl)cyclopropane(cas: 7051-34-5) is used as a synthetic building block for the introduction of the cyclopropylmethyl group. It was also used in the synthesis of 1,4-dienes via iron-catalyzed cross-coupling with alkenyl Grignard reagents.Formula: C4H7Br

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

The author of 《Mechanistic Characterization of (Xantphos)Ni(I)-Mediated Alkyl Bromide Activation: Oxidative Addition, Electron Transfer, or Halogen-Atom Abstraction》 were Diccianni, Justin B.; Katigbak, Joseph; Hu, Chunhua; Diao, Tianning. And the article was published in Journal of the American Chemical Society in 2019. SDS of cas: 7051-34-5 The author mentioned the following in the article:

Ni(I)-mediated single-electron oxidative activation of alkyl halides has been extensively proposed as a key step in Ni-catalyzed cross-coupling reactions to generate radical intermediates. There are four mechanisms through which this step could take place: oxidative addition, outer-sphere electron transfer, inner-sphere electron transfer, and concerted halogen-atom abstraction. Despite considerable computational studies, there is no exptl. study to evaluate all four pathways for Ni(I)-mediated alkyl radical formation. Herein, we report the isolation of a series of (Xantphos)Ni(I)-Ar complexes that selectively activate alkyl halides over aryl halides to eject radicals and form Ni(II) complexes. This observation allows the application of kinetic studies on the steric, electronic, and solvent effects, in combination with DFT calculations, to systematically assess the four possible pathways. Our data reveal that (Xantphos)Ni(I)-mediated alkyl halide activation proceeds via a concerted halogen-atom abstraction mechanism. This result corroborates previous DFT studies on (terpy)Ni(I)- and (py)Ni(I)-mediated alkyl radical formation, and contrasts with the outer-sphere electron transfer pathway observed for (PPh3)4Ni(0)-mediated aryl halide activation. This study of a model system provides insight into the overall mechanism of Ni-catalyzed cross-coupling reactions and offers a basis for differentiating electrophiles in cross-electrophile coupling reactions. In the experiment, the researchers used (Bromomethyl)cyclopropane(cas: 7051-34-5SDS of cas: 7051-34-5)

(Bromomethyl)cyclopropane(cas: 7051-34-5) is used as a synthetic building block for the introduction of the cyclopropylmethyl group. It was also used in the synthesis of 1,4-dienes via iron-catalyzed cross-coupling with alkenyl Grignard reagents.SDS of cas: 7051-34-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Safety of (Bromomethyl)cyclopropaneIn 2019 ,《Dual nickel- and photoredox-catalyzed reductive cross-coupling of aryl vinyl halides and unactivated tertiary alkyl bromides》 was published in Chemical Communications (Cambridge, United Kingdom). The article was written by Yu, Weijie; Chen, Long; Tao, Jiasi; Wang, Tao; Fu, Junkai. The article contains the following contents:

A novel reductive cross-coupling of aryl vinyl halides and unactivated tertiary alkyl bromides was realized via photoredox/nickel dual catalysis to produce vinyl arene derivatives bearing all-carbon quaternary centers with excellent E-selectivity. A stoichiometric metal reductant was avoided by employing com. available N,N,N’,N’-tetramethylethylenediamine (TMEDA) as the terminal reductant. In the experiment, the researchers used many compounds, for example, (Bromomethyl)cyclopropane(cas: 7051-34-5Safety of (Bromomethyl)cyclopropane)

(Bromomethyl)cyclopropane(cas: 7051-34-5) is used as a synthetic building block for the introduction of the cyclopropylmethyl group. It was also used in the synthesis of 1,4-dienes via iron-catalyzed cross-coupling with alkenyl Grignard reagents.Safety of (Bromomethyl)cyclopropane

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2022,Johnson, John Douglas; Teeples, Charles Reece; Akkawi, Nicholas Rajai; Wilkerson-Hill, Sidney M. published an article in Journal of the American Chemical Society. The title of the article was 《Efficient Synthesis of Orphaned Cyclopropanes Using Sulfones as Carbene Equivalents》.Formula: C4H7Br The author mentioned the following in the article:

Herein, a mechanistically distinct platform to transfer 1,1-dialkylcarbene units to olefins using carbometalation reactions of dialkyl sulfonyl anions was introduced. In presence of NaNH2 or n-BuLi in ethereal solvents, dialkyl sulfones reacted with styrenes and arylbutadienes between 23 and 70°C to produce corresponding 1,1-dialkylcyclopropanes, e.g., I [R1 = Me, Et, n-Bu, etc.; R2 = H, i-Bu, n-pentadecyl, etc.; R1R2 = (CH2)4, (CH2)5, (CH2)6]. Forty examples of this reactivity including 16 different styrenes (up to 89% isolated yield), 9 arylbutadienes (51-88% yield), and 13 different sulfones (46-80% yield) was reported. In addition, an example of a sequential cyclopropanation reaction using this method was reported. Preliminary mechanistic studies suggested a stepwise anionic process that was initiated by direct addition of sulfonyl anions to a carbon-carbon double bond. In the experiment, the researchers used (Bromomethyl)cyclopropane(cas: 7051-34-5Formula: C4H7Br)

(Bromomethyl)cyclopropane(cas: 7051-34-5) is used as a synthetic building block for the introduction of the cyclopropylmethyl group. It was also used in the synthesis of 1,4-dienes via iron-catalyzed cross-coupling with alkenyl Grignard reagents.Formula: C4H7Br

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Carbocation inside the cage: a periodical DFT study on the interaction of the C4H7+ system with alkali metal ion-exchanged zeolite Y》 was published in ARKIVOC (Gainesville, FL, United States) in 2020. These research results belong to Rosenbach, Nilton Jr.; Mota, Claudio J. A.. Recommanded Product: 7051-34-5 The article mentions the following:

Periodic DFT calculations at GGA-PPBE level were carried out with the goal of achieving better understanding of the influence of the polarity of the zeolite cavity on the stability of carbocations intermediates inside these materials. The results show that local electrostatic interactions play the major role of stabilizing such species on the zeolite surface. In the experiment, the researchers used many compounds, for example, (Bromomethyl)cyclopropane(cas: 7051-34-5Recommanded Product: 7051-34-5)

(Bromomethyl)cyclopropane(cas: 7051-34-5) is used as a synthetic building block for the introduction of the cyclopropylmethyl group. It was also used in the synthesis of 1,4-dienes via iron-catalyzed cross-coupling with alkenyl Grignard reagents.Recommanded Product: 7051-34-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Transition metal- and light-free radical borylation of alkyl bromides and iodides using silane》 was written by Sun, Beiqi; Zheng, Sihan; Mo, Fanyang. Recommanded Product: 7051-34-5This research focused ontransition metal light free radical borylation alkyl bromide iodide; crystal structure mol structure optimized boronic ester alkyl preparation; radical borylation alkyl bromide iodide silane mechanism DFT. The article conveys some information:

We report operationally simple and neutral conditions for borylation of alkyl bromides and iodides to alkyl boronic esters under transition metal- and light-free conditions. A series of substrates with a wide range of functional groups were effectively transformed into the borylation products in moderate to good yields. Mechanistic studies, including radical clock experiments and DFT calculations, gave detailed insight into the radical borylation process. In the experiment, the researchers used many compounds, for example, (Bromomethyl)cyclopropane(cas: 7051-34-5Recommanded Product: 7051-34-5)

(Bromomethyl)cyclopropane(cas: 7051-34-5) is used as a synthetic building block for the introduction of the cyclopropylmethyl group. It was also used in the synthesis of 1,4-dienes via iron-catalyzed cross-coupling with alkenyl Grignard reagents.Recommanded Product: 7051-34-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary