Category: 70-23-5

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 70-23-5, formula is C5H7BrO3, Name is Ethyl 3-bromo-2-oxopropanoate, Reference of 70-23-5

Hao, Zesheng;Yu, Bin;Gao, Wei;Chen, Haoyin;Yang, Dongyan;Lv, You;Zhang, Yue;Chen, Lei;Fan, Zhijin research published 《 Design, synthesis and fungicidal activity of pyrazole-thiazole carboxamide derivatives》, the research content is summarized as follows. Twenty-one novel pyrazole-thiazole carboxamide derivatives were rationally designed and synthesized I [R = 2-(p-tolyl)ethyl, 2-(2-chlorophenyl)ethyl, 2-[4-(trifluoromethoxy)phenyl]ethyl, etc.] and II. Bioassay results indicated that I [R = 2-(p-tolyl)ethyl, 2-(2-chlorophenyl)ethyl] (EC₅₀ = 5.11μg/mL), (EC₅₀ = 8.14μg/mL) resp. exhibited better in-vitro activities than fluxapyroxad (EC₅₀ = 11.93μg/mL) and thifluzamide (EC₅₀ = 22.12μg/mL) against Rhizoctonia cerealis. Particularly, compound I [R = 2-(2-chlorophenyl)ethyl] showed promising in-vivo protective activity against Rhizoctonia solani and Puccinia sorghi Schw. with 80% and 90% inhibition at 10μg/mL, resp. Pyrazole-thiazole I was a promising fungicide lead deserving for further derivation.

Reference of 70-23-5, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., 70-23-5.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 70-23-5, formula is C5H7BrO3, Name is Ethyl 3-bromo-2-oxopropanoate, Application In Synthesis of 70-23-5

Haroon, Muhammad;Akhtar, Tashfeen;Yousuf, Muhammad;Tahir, Muhammad Nawaz;Rasheed, Lubna;Zahra, Syeda Saniya;Haq, Ihsan ul;Ashfaq, Muhammad research published 《 Synthesis, crystal structure, Hirshfeld surface investigation and comparative DFT studies of ethyl 2-[2-(2-nitrobenzylidene)hydrazinyl]thiazole-4-carboxylate》, the research content is summarized as follows. The Et 2-[2-(2-nitrobenzylidene)hydrazinyl]thiazole-4-carboxylate, a thiazole ester, was synthesized by refluxing 1-(2-nitrobenzylidene)thiosemicarbazide and Et bromopyruvate. The compound is characterized by spectrometric, spectroscopic and single crystal (SC-XRD) techniques. Non-covalent interactions that are responsible for crystal packing are explored by Hirshfeld surface anal. All theor. calculations were performed by DFT quantum chem. methods using 6-311G(d,p) and cc-pVTZ basis sets and compared. Theor. harmonic frequencies of Et 2-[2-(2-nitrobenzylidene)hydrazinyl]thiazole-4-carboxylate were optimized. Confirmation of hydrogen bonding sites was analyzed by mol. electrostatic potential (MEP) and Mulliken population anal. The vibrational frequencies of characteristic functional groups and chem. shifts were found in good agreement with exptl. assignments. Frontier MO (FMO) revealed relatively small HOMO-LUMO (HOMO-LUMO) gape, which speaks off the nearly planar geometry and extended conjugation, as compared to the substituents with no conjugation possible. It has also been observed that -NO2 substituent plays a vital role for this relatively small HOMO-LUMO gape and overall electronic properties when compared with similar thiazole carboxylates. Et 2-[2-(2-nitrobenzylidene)hydrazinyl]thiazole-4-carboxylate was also evaluated for its anti-oxidant and anti-microbial activities.

70-23-5, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., Application In Synthesis of 70-23-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic compounds having carbon bonded to bromine are called organic bromides. 70-23-5, formula is C5H7BrO3, Name is Ethyl 3-bromo-2-oxopropanoate. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Application In Synthesis of 70-23-5.

Haroon, Muhammad;de Barros Dias, Mabilly Cox Holanda;Santos, Aline Caroline da Silva;Pereira, Valeria Rego Alves;Barros Freitas, Luiz Alberto;Balbinot, Rodolfo Bento;Kaplum, Vanessa;Nakamura, Celso Vataru;Alves, Luiz Carlos;Brayner, Fabio Andre;Leite, Ana Cristina Lima;Akhtar, Tashfeen research published 《 The design, synthesis, and in vitro trypanocidal and leishmanicidal activities of 1,3-thiazole and 4-thiazolidinone ester derivatives》, the research content is summarized as follows. Given this, novel 1,3-thiazoles I (Ar = Ph, 3-chlorophenyl, furan-2-yl, etc.; R = H, Me) and 4-thiazolidinones II (R¹ = (phenylmethylidene)aminyl, [(4-hydroxy-3-methoxyphenyl)methylidene]aminyl, 1,2,3,4-tetrahydronaphthalen-1-iminyl, etc.; R² = Me, Et) using bioisosteric and esterification strategies to develop improved and safer drug candidates were synthesized. Then, in vitro assays were performed, against Leishmania infantum and Leishmania amazonensis promastigotes, Trypanosoma cruzi trypomastigotes and amastigotes, for selected compounds I and II to determine IC₅₀ and SI, with cytotoxicity on LLC-MK2 cell lines. Overall, 1,3-thiazoles I exhibited better trypanocidal activity than 4-thiazolidinones II. The compound I[Ar = 2-bromophenyl, R = H] (III), an ortho-bromobenzylidene-substituted 1,3-thiazole (IC₅₀ = 0.83μM), is the most potent of them all. In addition, compounds I and II had negligible cytotoxicity in mammalian cells (CC₅₀ values > 50μM). Also noteworthy is the examination of the cell death mechanism of T. cruzi, which showed that compound III induced necrosis and apoptosis in the parasite. SEM anal. demonstrated that the treatment of Trypanosoma cruzi trypomastigote cells with the compound III at different IC₅₀ concentrations promoted alterations in the shape, flagella and body surface, inducing parasite death. Together, the data revealed a novel series of 1,3-thiazole structure-based compounds I with promising activity against Trypanosoma cruzi and Leishmania spp., broadening ways for scaffold optimization.

Application In Synthesis of 70-23-5, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., 70-23-5.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 70-23-5, formula is C5H7BrO3, Name is Ethyl 3-bromo-2-oxopropanoate, Computed Properties of 70-23-5

Groendyke, Brian J.;Nabet, Behnam;Mohardt, Mikaela L.;Zhang, Haisheng;Peng, Ke;Koide, Eriko;Coffey, Calvin R.;Che, Jianwei;Scott, David A.;Bass, Adam J.;Gray, Nathanael S. research published 《 Discovery of a Pyrimidothiazolodiazepinone as a Potent and Selective Focal Adhesion Kinase (FAK) Inhibitor》, the research content is summarized as follows. Focal adhesion kinase (FAK) is a tyrosine kinase with prominent roles in protein scaffolding, migration, angiogenesis, and anchorage-independent cell survival and is an attractive target for the development of cancer therapeutics. However, current FAK inhibitors display dual kinase inhibition and/or significant activity on several kinases. Although multi-targeted activity is at times therapeutically advantageous, such behavior can also lead to toxicity and confound chem.-biol. studies. We report a novel series of small mols. based on a tricyclic pyrimidothiazolodiazepinone core that displays both high potency and selectivity for FAK. Structure-activity relationship (SAR) studies explored modifications to the thiazole, diazepinone, and aniline “tail,” which identified lead compound BJG-03-025. BJG-03-025 displays potent biochem. FAK inhibition (IC₅₀ = 20 nM), excellent kinome selectivity, activity in 3D-culture breast and gastric cancer models, and favorable pharmacokinetic properties in mice. BJG-03-025 is a valuable chem. probe for evaluation of FAK-dependent biol.

Computed Properties of 70-23-5, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., 70-23-5.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic compounds having carbon bonded to bromine are called organic bromides. 70-23-5, formula is C5H7BrO3, Name is Ethyl 3-bromo-2-oxopropanoate. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Application of C5H7BrO3.

Gao, Yu-Qi;Hou, Yi;Chen, Junhan;Zhen, Yanxia;Xu, Dongyang;Zhang, Hongli;Wei, Hongbo;Xie, Weiqing research published 《 Asymmetric synthesis of 9-alkyl tetrahydroxanthenones via tandem asymmetric Michael/cyclization promoted by chiral phosphoric acid》, the research content is summarized as follows. A tandem asym. Michael-addition/cyclization of cyclic 1,3-dicarbonyl compounds to β,γ-unsaturated α-ketoesters catalyzed by chiral phosphoric acid is presented. This protocol provides a facile approach for the construction of enantioenriched 9-alkyl tetrahydroxanthenones, an ubiquitous framework found in a number of natural products and pharmaceutical mols., in high yields with good to high enantioselectivities.

70-23-5, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., Application of C5H7BrO3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 70-23-5, formula is C5H7BrO3, The most pervasive is the naturally produced bromomethane. Product Details of C5H7BrO3

Gholami Orimi, Fathali;Mirza, Behrooz;Hossaini, Zinatossadat research published 《 Fe₃O₄/ZnO/multi-walled carbon nanotubes magnetic nanocomposites promoted five components synthesis of new imidazole derivatives》, the research content is summarized as follows. Imidazole derivatives I (R = H, methoxycarbonyl, ethoxycarbonyl; R¹ = Me, Et; R² = ethoxycarbonyl, 4-methoxyphenyl, 4-nitrophenyl, etc.) in high yields using the five component reactions of N-methylimidazole, dialkyl acetylenedicarboxylates or propiolates RCCC(O)OR¹, α-haloketones R²C(O)CH₂Br, triphenyphosphine, and ammonium acetate in water at room temperature in the presence of nanocatalyst were synthesized. The Fe₃O₄/ZnO/multi-walled carbon nanotubes (MWCNTs) magnetic nanocomposites were utilized well as an organometallic catalyst in these reactions. This catalyst was synthesized utilizing the ionic liquid [OMIM]Br as a stabilizer and soft template. Also, this catalyst has high performance and improvement in the yield of the imidazoles and displayed significant reusability. In the synthesized compounds because of having imidazole core, the ability of antioxidant of some of them by diphenyl-picrylhydrazine (DPPH) radical trapping and power of ferric reduction experiment was studied. In addition, for investigation of antimicrobial activity of some imidazoles I, the disk diffusion experiments are utilized on Gram-pos. and Gram-neg. bacteria. The outcomes of this experiment exhibited that these generated compounds could avoid from growth of bacteria. Short time of reaction, high yields of product, and easy separation of catalyst and products are some advantages of this process.

Product Details of C5H7BrO3, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., 70-23-5.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Vinyl bromides undergo the Heck reaction, which involves C-C coupling with alkene to give substituted alkenes. 70-23-5, formula is C5H7BrO3, Name is Ethyl 3-bromo-2-oxopropanoate. Methyl bromide is a precursor in the manufacture of several chemicals and is employed as a soil sterilant, mainly for seed production. Synthetic Route of 70-23-5.

Fujiyoshi, Kohei;Kawashima, Shigehiro A.;Yamatsugu, Kenzo;Kanai, Motomu research published 《 A Single-Step Asymmetric Phosphodiester Synthesis from Alcohols with Phosphoenolpyruvate Phosphodiester》, the research content is summarized as follows. Phosphodiesters ROP(O)(OH)(OR¹) (12–31; R = 3-arylpropyl, phenethyl, carbohydrate, steroid, amino acid; R¹ = Me, Et) were prepared by organocatalytic transesterification of phosphoenolpyruvate (R¹O)₂P(O)OC(:CH₂)CO₂H in the presence of 1 equiv of Me nicotinate. Phosphodiesters are important structural motifs observed in a diverse field of mol. science. It is, thus, important to develop a simple and robust way to synthesize them from corresponding alcs. Here we report a single-step asym. phosphodiester synthesis from alcs. with phosphoenolpyruvate phosphodiesters as phosphoryl donors. This transformation allows for the use of various functionalized alcs. as substrates and would be useful for diverse fields including biol. and medicine.

Synthetic Route of 70-23-5, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., 70-23-5.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 70-23-5, formula is C5H7BrO3, Name is Ethyl 3-bromo-2-oxopropanoate. Organobromine compounds have fallen under increased scrutiny for their environmental impact., SDS of cas: 70-23-5.

Erigur, Esra Caner;Altug, Cevher;Angeli, Andrea;Supuran, Claudiu T. research published 《 Design, synthesis and human carbonic anhydrase I, II, IX and XII inhibitory properties of 1,3-thiazole sulfonamides》, the research content is summarized as follows. A series of novel 1,3-thiazole sulfonamides I [R = i-Pr, n-Bu, HOCH₂CH₂, Ph(CH₂)₄, etc.] has been designed, synthesized and studied their carbonic anhydrase (CA) inhibitory properties. The inhibition property of four human CA isoforms was investigated: hCA I, II, IX, and XII using the standard drug acetazolamide (AAZ) for comparison. The compounds I showed a wide range of inhibition potency towards the cytosolic enzyme hCA I. Nevertheless, the compounds I (R = n-Pr, i-Pr, HOCH₂CHMe, HOCHMeCH₂, MeOCH₂CH₂) have shown higher inhibition potential as compared to acetazolamide (KI = 250 nM). The abundant human cytosolic isoform, hCA II, was strongly inhibited by the most compounds in low nanomolar range (KI < 12.1 nM). On the other hand, almost all novel synthesized compounds have shown weaker inhibition potential as compared to acetazolamide against the tumor membrane- associated isoform hCA IX. Finally, the second tumor membrane-associated isoform, hCA XII, showed a wide range of potency that spanned from 9.3 to 729.6 nM.

SDS of cas: 70-23-5, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., 70-23-5.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 70-23-5, formula is C5H7BrO3, Name is Ethyl 3-bromo-2-oxopropanoate. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. HPLC of Formula: 70-23-5.

Ertas, Merve;Biltekin, Sevde Nur;Berk, Barkin;Yurttas, Leyla;Demirayak, Seref research published 《 Synthesis of some 5,6-diaryl-1,2,4-triazine derivatives and investigation of their cyclooxygenase (COX) inhibitory activity》, the research content is summarized as follows. Within this study, [(diaryltriazinyl)thio]-N-(benzo/thiazolyl)acetamide derivatives (I [R = H,Me, Cl, etc.; R¹ = H, Me, COOEt; R² = H, Me; R¹R² = (CH₂)₃]) were synthesized and COX inhibitory activities of the compounds were investigated. Compounds I [R = MeO; R¹ = H, Me, COOEt;R² = H; R¹ = R² = Me; R¹R² = (CH₂)₄] , which have a 4-methoxyphenyl group within their structures, showed strong inhibitory activity on COX-2 enzyme, even compound I [R = MeO; R¹ = R² = H] namely 2-{[5,6-bis(4-methoxyphenyl)-1,2,4-triazin-3-yl]thio}-N-(thiazol-2-yl)acetamide exhibited higher selectivity on this enzyme (IC₅₀:3.06 μM). Mol. docking studies were performed for compound I [R = MeO; R¹ = R² = H] on COX-1 and COX-2 enzymes and the results were found to support the mol.′s COX-2 selectivity.

HPLC of Formula: 70-23-5, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., 70-23-5.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 70-23-5, formula is C5H7BrO3, The most pervasive is the naturally produced bromomethane. Product Details of C5H7BrO3

Ezzatzadeh, Elham;Hargalani, Fariba Zamani;Shafaei, Faezeh research published 《 Bio-Fe₃O₄-MNPs Promoted Green Synthesis of Pyrido[2,1-a]isoquinolines and Pyrido[1,2-a]quinolines: Study of Antioxidant and Antimicrobial Activity》, the research content is summarized as follows. In this work, synthesis of pyrido[2,1-a]isoquinolines and pyrido[1,2-a]quinolines in excellent yield using multicomponent reaction of isoquinoline, Me malonyl chloride, alkyl bromides, and triphenylphosphine in the presence of catalytic amount of Fe₃O₄-MNPs in water at 80° were investigated. The reduction of ferric chloride solution with Clover Leaf water extract resulted in the synthesis of magnetic iron oxide nanoparticles (Fe₃O₄-NPs) as a green method. The antioxidant activity was studied for some newly synthesized compounds using the DPPH radical trapping and ferric ion reduction experiments and results were compared with synthetic antioxidants (TBHQ and BHT). These compounds showed trace DPPH radical trapping and excellent reducing strength of ferric ion. The antimicrobial activity of some synthesized compounds was studied employing the disk diffusion test on Gram-pos. bacteria and Gram-neg. bacteria. The results of disk diffusion test showed that these compounds prevented the bacterial growth.

70-23-5, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., Product Details of C5H7BrO3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary