Category: 698-00-0

Reference of 698-00-0, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 698-00-0, name is 2-Bromo-N,N-dimethylaniline belongs to bromides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.

N,N-dimethyl-o-bromoaniline (4 g, 20 mmol) was added to anhydrous tetrahydrofuran (100 mL) at -78 C., and 2.5M n-butyllithium (10 mL, 25 mmol) was then slowly added dropwise and stirred for 2 hours. Trimethylborate (2.6 g, 25 mmol) was added to the reaction mixture and stirred for another 2 hours. After warming to room temperature, the reaction was quenched by the addition of 0.1N hydrochloric acid solution (200 mL) and the mixture was extracted with dichloromethane (150 mL*3), then washed with water (150 mL*3). The organic phase was concentrated under reduced pressure to give compound 41-a (3.0 g, yield 91%). LC-MS (ESI): m/z=166[M+H]+.

The synthetic route of 2-Bromo-N,N-dimethylaniline has been constantly updated, and we look forward to future research findings.

Reference:
Patent; GUANGZHOU MAXINOVEL PHARMACEUTICALS CO., LTD.; XU, Zusheng; ZHANG, Nong; WANG, Tinghan; SUN, Qingrui; WANG, Yuguang; (90 pag.)US2018/208604; (2018); A1;,
Bromide – Wikipedia,
bromide – Wiktionary

Electric Literature of 698-00-0, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 698-00-0, name is 2-Bromo-N,N-dimethylaniline, This compound has unique chemical properties. The synthetic route is as follows.

Synthesis of 2-(di-l-adamantylphosphino)-N^V-dimethylaniline (L2).[0287] Pd(OAc)2 (6.3 mg, 0.028 mmol) was added to a glass vial and dissolved in toluene (2 mL). This solution was then transferred to a vial containing DiPPF(l,l’-bis(diisopropylphosphino)ferrocene; 14.2 mg, 0.034 mmol) and was left to stir for 10 minutes. To a separate glass vial containing NaOtBu (192 mg, 2.0 mmol) was added a solution of (l-adamantyl)2PH (410 mg, 1.36 mmol) in 2 mL toluene, followed by2-bromo-NjV-dimethylaniline (230 L, 1.4 mmol), and the Pd(OAc)2/DiPPF solution, after which the vial was sealed with a cap containing a PTFE septum. The mixture was stirred for 20 h at 110 C, at which point the reaction was deemed complete on the basis of 31P NMR data obtained from an aliquot of the reaction mixture. The reaction mixture was then allowed to cool and was passed through a plug of silica, followed by washing of the plug with 40 mL of CH2C12. The combined eluent was collected and the solvent was removed in vacuo. The resulting pale orange solid was washed with cold hexanes (2 x 4 mL). Removal of volatile materials in vacuo yielded the product as an off-white powder (0.424 g, 1.01 mmol; 74 % yield). 1H NMR (CDC13): delta 7.71 (m, 1H, Ar-H), 7.32 (m, 1H, Ar-H), 7.20 (m, 1H, Ar-H), 7.05 (m, 1H, Ar-H), 2.71 (s, 6H, N(CH3)2), 2.01-1.89 (m, 18Eta, 1-Ad), 1.67 (s, 12Eta, 1-Ad). 13C{ ‘H} NMR (CDCI3): delta 161.6 (d, JPC = 21.6 Hz, Cquat), 137.4 (d, JPC = 3.3 Hz), 131.1 (d, JPC = 22.9 Hz, Cquat), 129.6, 122.2, 120.6 (d, Jpc = 3.9 Hz), 46.1 (d, Jpc = 4.2 Hz, N(CH3)2), 41.8 (d, Jpc = 13.0 Hz, CH2), 37.1 (CH2), 29.0 (d, /PC = 8.6 Hz, CH). 31P{ 1H} NMR (CDC13): delta 20.1. HRMS (ESI/[M+H]+) calcd. for C28H40N1P1: 422.2971. Found: 422.2978. Anal. Calcd for C^fttoPiNi: C 79.77; H 9.56; N 3.32. Found: C 79.47; H 9.46; N 3.31.

The chemical industry reduces the impact on the environment during synthesis 2-Bromo-N,N-dimethylaniline. I believe this compound will play a more active role in future production and life.

Reference:
Patent; DALHOUSIE UNIVERSITY; LUNDGREN, Rylan, J.; STRADIOTTO, Mark; WO2012/68335; (2012); A2;,
Bromide – Wikipedia,
bromide – Wiktionary

Electric Literature of 698-00-0,Some common heterocyclic compound, 698-00-0, name is 2-Bromo-N,N-dimethylaniline, molecular formula is C8H10BrN, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

General procedure: Under air, 1 (0.2 mmol), NH4I (0.8 mmol), 70% TBHP in water (2.4 mmol) and DMSO (0.5 mL) were added to a 10 mL Schlenk tube sealed with a Teflon lined cap. The reaction mixture was stirred at 90 C for 4 h in an oil bath. Upon completion, the reaction mixture was left to cool to room temperature and slowly quenched with anhydrous sodium sulfite. The reaction mixture was then diluted with ethyl acetate (5 mL) and then washed with water (5 × 5 mL). The aqueous layer was extracted with EtOAc (3 × 5 mL). The combined organic layers were dried over Na2SO4. The filtrate was concentrated and the crude product was purified by column chromatography on silica gel with petroleum ether (60-90 C)/ethyl acetate eluent. Characterisation data are consistent with literature data.

The synthetic route of 698-00-0 has been constantly updated, and we look forward to future research findings.

Reference:
Article; Shao, Ying; Zheng, Hao; Wu, Zhuhong; Huang, Lei; Tong, Jingjing; Wu, Ming; Sun, Xiaoqiang; Journal of Chemical Research; vol. 41; 9; (2017); p. 504 – 508;,
Bromide – Wikipedia,
bromide – Wiktionary

Synthetic Route of 698-00-0, A common heterocyclic compound, 698-00-0, name is 2-Bromo-N,N-dimethylaniline, molecular formula is C8H10BrN, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

General procedure: TMSCN (0.15 mL, 1.0 mmol) was added to a stirred mixture of PIFA (430 mg,1.0 mmol) and 3.0 mL of DCE at room temperature. After 40 min, Na2SO4(36 mg, 0.25 mmol) and tertiary amine (0.5 mmol) were then added to themixture successively and reacted for overnight. Subsequently,the mixture was poured into aqueous NaHCO3 solution and Na2S2O3solution and extracted with dichloromethane. The organic layer was washedwith brine, dried over sodium sulfate and concentrated in vacuo. Purificationby column chromatography on silica gel produced alpha-aminonitriles.

The synthetic route of 698-00-0 has been constantly updated, and we look forward to future research findings.

Reference:
Article; Shen, Hang; Zhang, Xiaohui; Liu, Qing; Pan, Jing; Hu, Wen; Xiong, Yan; Zhu, Xiangming; Tetrahedron Letters; vol. 56; 41; (2015); p. 5628 – 5631;,
Bromide – Wikipedia,
bromide – Wiktionary

Reference of 698-00-0, Redox catalysis has been broadly utilized in electrochemical synthesis due to its kinetic advantages over direct electrolysis. The appropriate choice of redox mediator can avoid electrode passivation and overpotential. 698-00-0, Name is 2-Bromo-N,N-dimethylaniline, SMILES is CN(C)C1=CC=CC=C1Br, belongs to bromides-buliding-blocks compound. In a article, author is Sen, Partha Pratim, introduce new discover of the category.

Probing the versatility of metallo-electro hybrid catalysis: enabling access towards facile C-N bond formation

The development of versatile and mild methodologies for C-N bond construction has always been a hot topic of interest in synthetic organic chemistry. In recent years, electrochemistry has emerged as a promising green and sustainable environmentally benign approach to carry out these transformations under mild conditions utilizing electrons as oxidizing/reducing agents. The current state-of-the-art in combining electrocatalysis with transition metal catalysis has gained significant attention. This hybrid synthetic methodology has increasingly become a common tool and offers many potential advantages compared to direct electrolysis. This review comprehensively highlights recent developments in the merging of transition metal catalysis in electro-organic synthesis for the facile construction of C-N bonds. In this review major emphasis is given to mechanistic investigations and their synthetic applications of this hybrid catalysis.

Reference of 698-00-0, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. I hope my blog about 698-00-0 is helpful to your research.

Synthetic Route of 698-00-0, Enzymes are biological catalysts that produce large increases in reaction rates and tend to be specific for certain reactants and products. 698-00-0, Name is 2-Bromo-N,N-dimethylaniline, SMILES is CN(C)C1=CC=CC=C1Br, belongs to bromides-buliding-blocks compound. In a article, author is Wang, Fang, introduce new discover of the category.

Adsorption of Bisphenol A on Peanut Shell Biochars: The Effects of Surfactants

Bisphenol A (BPA) is a typical endocrine-disrupting chemical. The removal of BPA has raised much concerns in recent years. This paper examined the adsorption behavior of BPA to biochars and the different effects of cationic, anionic, and nonionic surfactants. The results indicated that peanut shell biochars prepared at 300 degrees C (BC300), 500 degrees C (BC500), and 700 degrees C (BC700) showed strong adsorption affinity for BPA, and the adsorption affinity of biochars increased with the increase of pyrolysis temperature. The range of log K-d values was 2.83 similar to 3.71, 2.91 similar to 4.57, and 3.24 similar to 5.50 for BC300, BC500, and BC700, respectively. Both the type of surfactants and the properties of biochars could affect the adsorption behavior of BPA. Cetyltrimethyl ammonium bromide (CTAB) showed negligible effect on the adsorption of BPA on BC300, and the inhibition effect of CTAB was stronger with the increase of biochar pyrolysis temperature. Tween 20 and sodium dodecyl benzene sulfonate (SDBS) showed stronger inhibition effect than CTAB, especially on BC300. This is likely because the inhibition effect caused by competition of CTAB may be counterbalanced by the enhancement caused by the partitioning effect by adsorbed CTAB and the bridge effect between the -NH4+ group of CTAB and the phenol group on BPA/O-functional groups of biochars, whereas Tween 20 and SDBS do not have this bridge effect advantage. This study could provide insightful information for the application of biochars in removal of BPA.

Synthetic Route of 698-00-0, The reactant in an enzyme-catalyzed reaction is called a substrate. Enzyme inhibitors cause a decrease in the reaction rate of an enzyme-catalyzed reaction.I hope my blog about 698-00-0 is helpful to your research.

A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 698-00-0, Name is 2-Bromo-N,N-dimethylaniline, molecular formula is C8H10BrN. In an article, author is Yang, Jun,once mentioned of 698-00-0, Quality Control of 2-Bromo-N,N-dimethylaniline.

Silver-Enabled General Radical Difluoromethylation Reaction with TMSCF2H

A silver-mediated oxidative difluoromethylation of styrenes and vinyl trifluoroborates with TMSCF2H is reported for the first time. This method enables direct and facile access to CF2H-alkenes from abundant alkenes with excellent functional-group compatibility. Moreover, this Ag/TMSCF2H protocol could further enable a series of radical difluoromethylation reactions of a wide array of substrates, offering a generic and complementary platform for the construction of diversified C-CF2H bonds.

Interested yet? Keep reading other articles of 698-00-0, you can contact me at any time and look forward to more communication. Quality Control of 2-Bromo-N,N-dimethylaniline.

In an article, author is Slimi, B., once mentioned the application of 698-00-0, Application In Synthesis of 2-Bromo-N,N-dimethylaniline, Name is 2-Bromo-N,N-dimethylaniline, molecular formula is C8H10BrN, molecular weight is 200.0757, MDL number is MFCD00013522, category is bromides-buliding-blocks. Now introduce a scientific discovery about this category.

Thin Film of Perovskite (Mixed-Cation of Lead Bromide FA(1-x)MA(x)PbBr) Obtained by One-Step Method

Perovskite materials for solar cell applications were prepared by a one-step method. In the following work, the spin coating technique was used for organic-inorganic hybrid perovskite formamidinium lead tribromide (FAPbBr(3)), methylammonium lead tribromide (MAPbBr(3)) and formamidinium methylammonium lead tribromide (FA(1-x)MA(x)PbBr(3)).Thin films of mixed FA(1-x)MA(x)PbBr(3) (x = 0-1) perovskites deposited on indium tin oxide glass substrates were obtained by mixing FAPbBr(3) and MAPbBr(3) in different proportions. Structural x-ray diffraction (XRD), morphological (Scanning Electron Microscopy (SEM) and energy dispersive x-ray spectroscopy (EDX) and optical (uv-visible spectroscopy (UV-Vis) proprieties were investigated for all synthesized perovskites as a function of the MA/FA ratio. The (XRD) analysis shows the formation of a cubic-phase perovskite with space group Pm-3 m in the composition range 0 <= x <= 1. High absorbance levels were obtained in the infrared region 500-900 nm for mixed perovskites FAMAPbBr(3). The estimated energy band-gap from the absorbance spectral measurements for FAMAPbBr(3) thin films was in the range of 2.2 eV for FAPbBr(3) and 2.3 eV for MAPbBr(3), respectively. The photoluminescence emission of mixed FA/MA perovskite thin films was located in intermediate values between 580 nm and 555 nm. If you are interested in 698-00-0, you can contact me at any time and look forward to more communication. Application In Synthesis of 2-Bromo-N,N-dimethylaniline.

Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 698-00-0, Name is 2-Bromo-N,N-dimethylaniline, SMILES is CN(C)C1=CC=CC=C1Br, belongs to bromides-buliding-blocks compound. In a document, author is Qu, Yi, introduce the new discover, Name: 2-Bromo-N,N-dimethylaniline.

Palladium-mediated Suzuki-Miyaura Cross-Coupling Reaction of Potassium Boc-protected aminomethyltrifluoroborate with DNA-Conjugated aryl bromides for DNA-Encoded chemical library synthesis

A mild reaction for DNA-compatible, palladium promoted Suzuki-Miyaura cross-coupling reaction of potassium Boc-protected aminomethyltrifluoroborate with DNA-conjugated aryl bromides has been developed efficiently. This novel DNA encoded chemistry reaction proceeded well with a wide range of functional group tolerance, including aryl bromides and heteroaryl bromides. Further, the utility our DNA conjugated aminomethylated arene products is demonstrated by reaction with various types of reagents (including amide formation with carboxylic acids, alkylation with aldehydes, and carbamoylation with amines) as would be desired for the production of a DNA encoded library. (C) 2020 Elsevier Inc. All rights reserved.

The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 698-00-0 is helpful to your research. Name: 2-Bromo-N,N-dimethylaniline.

In an article, author is Rahim, Md Abdur, once mentioned the application of 698-00-0, Name is 2-Bromo-N,N-dimethylaniline, molecular formula is C8H10BrN, molecular weight is 200.0757, MDL number is MFCD00013522, category is bromides-buliding-blocks. Now introduce a scientific discovery about this category, SDS of cas: 698-00-0.

Influence of Different Additives on the Interaction of Quinolone Antibiotic Drug with Surfactant: Conductivity and Cloud Point Measurement Study

Conductometric and cloud point (CP) measurement studies have been performed to investigate the interaction of tetradecyltrimethylammonium bromide (TTAB) and Triton (R) X-100 (TX-100) with ciprofloxacin hydrochloride (CFH) in different solvents over the temperature range of 295.15-315.15 K. CFH is used for the treatment of various bacterial infections. The observed critical micelle concentration (CMC) values of TTAB were found to be reduced in the presence of electrolytes (Na2SO4/Na3PO4), and this reduction proceeds with the elevation of salt concentration. The order of the CMC of TTAB follows the trend: cmcH2O > cmcNa3PO4 >cmcNa2SO4. The observed CMC values of TTAB were found to increase with increasing temperature and decrease with increasing concentration of CFH in aqueous medium. The values of Gibbs free energy of micellization ( increment Gmo) for the TTAB/TTAB + CFH mixture were found to be negative, implying spontaneous micellization. The estimated CP of TX-100 decreases with increasing concentration of TX-100 in aqueous medium. The CP values first decrease with increasing concentration of CFH and then increase at higher concentration of CFH almost in all cases investigated. The values of free energy of clouding were found to be positive in all cases studied implying that phase separation of TX-100 was nonspontaneous. The other thermodynamic parameters associated with the micellization of TTAB and the phase separation of TX-100 were estimated and explained.

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