Category: 69272-50-0

Adding a certain compound to certain chemical reactions, such as: 69272-50-0, name is 3,6-Dibromobenzene-1,2-diamine, belongs to bromides-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 69272-50-0, Recommanded Product: 3,6-Dibromobenzene-1,2-diamine

Preparation of 5,8-dibromodiphenylquinoxaline (CH-b) A solution of 5.3 g (20 mmol) of 3,6-dibromo-1,2-phenylenediamine 1, 4 g (19 mmol) of benzil 2b, 4.2 g of sodium acetate and 150 ml of glacial acetic acid were refluxed for 4 hours. The precipitate was filtered off, washed with 100 ml of water and recrystallized twice from dioxane. Drying under reduced pressure at 50 C. gave the pure product in the form of colorless crystals, which according to HPLC had a purity of about 99.5%. The yield was 6.45 g (73%). 1H NMR (CDCl3, 500 MHz): [ppm]=7.92 (s, 2H), 7.67 (d, 3JHH=1.67 Hz, 2H), 6.66 (d, 3JHH=1.67 Hz, 2H), 7.37 (m, 6H).

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 3,6-Dibromobenzene-1,2-diamine, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; Covion Organic Semiconductors GmbH; US2007/265473; (2007); A1;,
Bromide – Wikipedia,
bromide – Wiktionary

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 69272-50-0, name is 3,6-Dibromobenzene-1,2-diamine belongs to bromides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. SDS of cas: 69272-50-0

In a flask,Intermediate 2-1 (17g, 64.4mmol),Benzil (13.5g, 64.4mmol) and acetic acid (400ml),Stirring,Heated to 90C,Stirring 3h.Cooling to room temperature,Solid separated.filter,The crude product was recrystallized from ethanol,Light yellow powder 21g,75% yield.

The synthetic route of 69272-50-0 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Shanghai Taoe Chemical Technology Co., Ltd.; Huang, Jinhai; Su, Jianhua; (22 pag.)CN105753849; (2016); A;,
Bromide – Wikipedia,
bromide – Wiktionary

Synthetic Route of 69272-50-0, The chemical industry reduces the impact on the environment during synthesis 69272-50-0, name is 3,6-Dibromobenzene-1,2-diamine, I believe this compound will play a more active role in future production and life.

In a dry 100 mL flask, compound 1 (0.59 g, 2 mmol) and NaBH4 (0.76 g, 20 mmol) were mixed inethanol (40 mL) for 1 h at RT, and then refluxed for 4 h under a nitrogen atmosphere. After coolingto RT, water was added and filtered. The residue was dried in vacuum. Then the crude product andsodium acetate (0.33 g, 4 mmol) were added to a solution of benzil (0.42 g, 2 mmol) in anhydrousethanol (30 mL) under a nitrogen atmosphere. The mixture was refluxed for 24 h. After cooling to RT,the solvent was removed under reduced pressure and the residue was purified by silica gel columnchromatography (eluent: n-hexane:CH2Cl2 = 4:1) to give a pale yellow solid (yield 72.0%, 0.75 g).1H-NMR (400 MHz, CDCl3,delta ): 7.91(s, 2H), 7.65-7.66(m, 4H), 7.34-7.41(m, 6H). 13C-NMR (100 MHz,CDCl3,delta ): 154.15, 139.36, 137.95, 133.10, 130.26, 129.59, 128.38, 123.74.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 3,6-Dibromobenzene-1,2-diamine, other downstream synthetic routes, hurry up and to see.

Reference:
Article; Wu, Zhonglian; Jiang, Huanxiang; Wang, Xingzhu; Yan, Lei; Zeng, Wei; Wu, Xiu-Gang; Zhuang, Haiyu; Zhu, Wen; Yang, Renqiang; Molecules; vol. 24; 1; (2019);,
Bromide – Wikipedia,
bromide – Wiktionary

Reference of 69272-50-0, These common heterocyclic compound, 69272-50-0, name is 3,6-Dibromobenzene-1,2-diamine, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

3,6-Dibromobenzene-1,2-diamine with round flask equipped with a condenser (compound 2-a) (1g) and phenanthrene-9,10-dione (0.8 g) after the into the respective acetate, 30mL ethanol and 30 after the injection, each mL, was added the temperature to 80 C, and reacted for 24 hours. If after the completion of the reaction through the methanol, the resulting solid filter using methanol to afford a yellow solid 10,13-dibromodibenzo [a, c] phenazine (compound C). (Yield: 68%).

Statistics shows that 3,6-Dibromobenzene-1,2-diamine is playing an increasingly important role. we look forward to future research findings about 69272-50-0.

Reference:
Patent; Pusan National University Industry-Academic Cooperation Foundation; Hwang, Do Hun; Kim, Ji Hun; Kim, Hee Woon; Im, Jong Min; (52 pag.)KR101495152; (2015); B1;,
Bromide – Wikipedia,
bromide – Wiktionary

Related Products of 69272-50-0,Some common heterocyclic compound, 69272-50-0, name is 3,6-Dibromobenzene-1,2-diamine, molecular formula is C6H6Br2N2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

1) Preparation of 5,8-dibromo-2,3-bis(phenyl)quinoxaline, the Chemical Equation Thereof is The detailed preparation procedure is as follows: 3,6-dibromo-o-phenylene diamine (1.0 g, 3.7 mmol) was added to a solution of compound benzil (0.39 g, 1.84 mmol) in acetic acid (20 mL) at 120?, then the mixture was mixed uniformly. After refluxed for 12 hours, the fluid reactant was poured into water, and neutralized with sodium bicarbonate until neutral, then extracted with chloroform and washed with saturated brine, dried over anhydrous sodium sulfate, then it was vacuum evaporated to remove the solvent, and the resulting crude product was purified by column chromatography to give a white solid, and then it was purified by recrystallization from chloroform/n-hexane to give a white solid powder. The test result is: MS (EI) m/z: 440(M+).

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 3,6-Dibromobenzene-1,2-diamine, its application will become more common.

Reference:
Patent; Ocean’s King Lighting Science & Technology Co., Ltd.; Zhou, Mingjie; Huang, Jie; Xu, Erjian; US8853348; (2014); B2;,
Bromide – Wikipedia,
bromide – Wiktionary

69272-50-0, name is 3,6-Dibromobenzene-1,2-diamine, belongs to bromides-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. 69272-50-0

Dissolve 3,6-dibromobenzene-1,2-diamine (10g, 37mmol) and 1,2-diphenyl-1,2-ethanedione (7.9g, 37mmol) in ethanol (250ml, 0.15M) in a two-neck round bottom flask And refluxed under nitrogen at 100 C. for one day.The temperature was lowered to room temperature and filtered to obtain Compound 2-A (light yellow solid). (Yield 16g, Yield 96%)

Statistics shows that 69272-50-0 is playing an increasingly important role. we look forward to future research findings about 3,6-Dibromobenzene-1,2-diamine.

Reference:
Patent; LG Chem, Ltd.; Lee Ji-yeong; Kim Sang-a; Ryu Seung-jun; Kim Ji-hun; (26 pag.)KR2019/86210; (2019); A;,
Bromide – Wikipedia,
bromide – Wiktionary