Category: 6911-87-1

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 6911-87-1, formula is C7H8BrN, Name is 4-Bromo-N-methylaniline. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Name: 4-Bromo-N-methylaniline.

Daneshmand, Pargol;Rosca, Sorin-Claudiu;Dalhoff, Rosalie;Yin, Kejun;DiPucchio, Rebecca C.;Ivanovich, Ryan A.;Polat, Dilan E.;Beauchemin, Andre M.;Schafer, Laurel L. research published 《 Cyclic Ureate Tantalum Catalyst for Preferential Hydroaminoalkylation with Aliphatic Amines: Mechanistic Insights into Substrate Controlled Reactivity》, the research content is summarized as follows. The efficient and catalytic amination of unactivated alkenes with simple secondary alkyl amines is preferentially achieved. A sterically accessible, N,O-chelated cyclic ureate tantalum catalyst was prepared and characterized by X-ray crystallog. This optimized catalyst can be used for the hydroaminoalkylation of 1-octene with a variety of aryl and alkyl amines, but notably enhanced catalytic activity can be realized with challenging N-alkyl secondary amine substrates. This catalyst offers turnover frequencies of up to 60 h^-1, affording full conversion at 5 mol% catalyst loading in approx. 20 min with these nucleophilic amines. Mechanistic investigations, including kinetic isotope effect (KIE) studies, reveal that catalytic turnover is limited by protonolysis of the intermediate 5-membered azametallacycle. A Hammett kinetic anal. shows that catalytic turnover is promoted by electron rich amine substrates that enable catalytic turnover. This more active catalyst is shown to be effective for late stage drug modification.

Name: 4-Bromo-N-methylaniline, 4-Bromo-N-methylaniline is a aniline based compound known to exhibit mutagenic properties.
4-Bromo-N-methylaniline is a useful research compound. Its molecular formula is C7H8BrN and its molecular weight is 186.05 g/mol. The purity is usually 95%.
4-Bromophenylmethylamine is an organic compound that has anti-inflammatory properties and is used as a pharmaceutical. It belongs to the group of amines. The hydrolysis of 4-bromophenylmethylamine by hydrochloric acid produces phenol and bromamine (NHBr). The reaction system can be used to synthesize a number of compounds, including anilines, benzofurans, and other aromatic compounds. 4-Bromophenylmethylamine reacts with muscle tissue in a similar manner as acetaminophen does. This drug also has been shown to have significant effects on the energy metabolism in the muscles of rats that are given carbon source., 6911-87-1.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic compounds having carbon bonded to bromine are called organic bromides. 6911-87-1, formula is C7H8BrN, Name is 4-Bromo-N-methylaniline. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Synthetic Route of 6911-87-1.

Cheng, Hanchao;Lam, Tsz-Lung;Liu, Yungen;Tang, Zhou;Che, Chi-Ming research published 《 Photoinduced Hydroarylation and Cyclization of Alkenes with Luminescent Platinum(II) Complexes》, the research content is summarized as follows. Photoinduced hydroarylation of alkenes is an appealing synthetic strategy for arene functionalization. Herein, we demonstrated that aryl radicals generated from electron-deficient aryl chlorides/bromides could be trapped by an array of terminal/internal aryl alkenes in the presence of [Pt(ON̂ĈN̂)] under visible-light (410 nm) irradiation, affording anti-Markonikov hydroarylated compounds in up to 95% yield. Besides, a protocol for [Pt(ON̂ĈN̂)]-catalyzed intramol. photocyclization of acrylanilides to give structurally diverse 3,4-dihydroquinolinones has been developed.

Synthetic Route of 6911-87-1, 4-Bromo-N-methylaniline is a aniline based compound known to exhibit mutagenic properties.
4-Bromo-N-methylaniline is a useful research compound. Its molecular formula is C7H8BrN and its molecular weight is 186.05 g/mol. The purity is usually 95%.
4-Bromophenylmethylamine is an organic compound that has anti-inflammatory properties and is used as a pharmaceutical. It belongs to the group of amines. The hydrolysis of 4-bromophenylmethylamine by hydrochloric acid produces phenol and bromamine (NHBr). The reaction system can be used to synthesize a number of compounds, including anilines, benzofurans, and other aromatic compounds. 4-Bromophenylmethylamine reacts with muscle tissue in a similar manner as acetaminophen does. This drug also has been shown to have significant effects on the energy metabolism in the muscles of rats that are given carbon source., 6911-87-1.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 6911-87-1, formula is C7H8BrN, Name is 4-Bromo-N-methylaniline. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Application In Synthesis of 6911-87-1.

Contino, Marialessandra;Guglielmo, Stefano;Riganti, Chiara;Antonello, Giulia;Perrone, Maria Grazia;Giampietro, Roberta;Rolando, Barbara;Fruttero, Roberta;Colabufo, Nicola A. research published 《 One molecule two goals: A selective P-glycoprotein modulator increases drug transport across gastro-intestinal barrier and recovers doxorubicin toxicity in multidrug resistant cancer cells》, the research content is summarized as follows. In the present study a series of tetrahydroisoquinoline derivatives were synthesized and evaluated for their activity towards three ABC transporters, P-gp, MRP1 and BCRP. The compounds proved to be selective against P-gp. One of them, 8b, displayed activity in the nanomolar range (EC₅₀ = 94 nM). Thus, compound 8b was tested for its ability to restore the cytotoxic activity of a well-known anti-cancer agent and P-gp substrate, doxorubicin, as first proof of concept. Moreover, compound 8b was also tested in an in vitro model of competent gastro-intestinal (GI) barrier (Caco-2 cells) for its ability to inhibit P-gp, present on luminal side, and increase the apical-to-basolateral transport of several structurally uncorrelated drugs, belonging to different therapeutic areas but actively excreted by P-gp. Notably the transport of the drugs across the GI barrier was increased by a concentration of 8b devoid of toxicity and of perturbing effects on barrier function. An in vitro simulated digestion process was set up: interestingly the effect of 8b on the transport of digoxin was preserved also after the simulated digestion process. This result may suggest 8b as a safe and effective P-gp modulator that can increase the bioavailability of a wide spectrum of drugs administered per os, improving their transport across the GI barrier.

6911-87-1, 4-Bromo-N-methylaniline is a aniline based compound known to exhibit mutagenic properties.
4-Bromo-N-methylaniline is a useful research compound. Its molecular formula is C7H8BrN and its molecular weight is 186.05 g/mol. The purity is usually 95%.
4-Bromophenylmethylamine is an organic compound that has anti-inflammatory properties and is used as a pharmaceutical. It belongs to the group of amines. The hydrolysis of 4-bromophenylmethylamine by hydrochloric acid produces phenol and bromamine (NHBr). The reaction system can be used to synthesize a number of compounds, including anilines, benzofurans, and other aromatic compounds. 4-Bromophenylmethylamine reacts with muscle tissue in a similar manner as acetaminophen does. This drug also has been shown to have significant effects on the energy metabolism in the muscles of rats that are given carbon source., Application In Synthesis of 6911-87-1

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic compounds having carbon bonded to bromine are called organic bromides. 6911-87-1, formula is C7H8BrN, Name is 4-Bromo-N-methylaniline. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Application of C7H8BrN.

Chen, Yong-Jia;Liu, Hua;Zhang, Shao-Yong;Li, Hu;Ma, Kun-Yuan;Liu, Ying-Qian;Yin, Xiao-Dan;Zhou, Rui;Yan, Yin-Fang;Wang, Ren-Xuan;He, Ying-Hui;Chu, Qing-Ru;Tang, Chen research published 《 Design, Synthesis, and Antifungal Evaluation of Cryptolepine Derivatives against Phytopathogenic Fungi》, the research content is summarized as follows. Inspired by the widely antiphytopathogenic application of diversified derivatives from natural sources, cryptolepine and its derivatives were subsequently designed, synthesized, and evaluated for their antifungal activities against four agriculturally important fungi Rhizoctonia solani, Botrytis cinerea, Fusarium graminearum, and Sclerotinia sclerotiorum. The results obtained from in vitro assay indicated that compounds showed great fungicidal property against B. cinerea (EC₅₀ < 4μg/mL); especially, I presented significantly prominent inhibitory activity with an EC₅₀ of 0.027μg/mL. In the pursuit of further expanding the antifungal spectrum of cryptolepine, ring-opened compound II produced better activity with an EC₅₀ of 3.632μg/mL against R. solani and an EC₅₀ of 5.599μg/mL against F. graminearum. Furthermore, I was selected to be a candidate to investigate its preliminary antifungal mechanism to B. cinerea, revealing that not only spore germination was effectively inhibited and the normal physiol. structure of mycelium was severely undermined but also detrimental reactive oxygen was obviously accumulated and the normal function of the nucleus was fairly disordered. Besides, in vivo curative experiment against B. cinerea found that the therapeutic action of I was comparable to that of the pos. control azoxystrobin. These results suggested that compound I could be regarded as a novel and promising agent against B. cinerea for its valuable potency.

6911-87-1, 4-Bromo-N-methylaniline is a aniline based compound known to exhibit mutagenic properties.
4-Bromo-N-methylaniline is a useful research compound. Its molecular formula is C7H8BrN and its molecular weight is 186.05 g/mol. The purity is usually 95%.
4-Bromophenylmethylamine is an organic compound that has anti-inflammatory properties and is used as a pharmaceutical. It belongs to the group of amines. The hydrolysis of 4-bromophenylmethylamine by hydrochloric acid produces phenol and bromamine (NHBr). The reaction system can be used to synthesize a number of compounds, including anilines, benzofurans, and other aromatic compounds. 4-Bromophenylmethylamine reacts with muscle tissue in a similar manner as acetaminophen does. This drug also has been shown to have significant effects on the energy metabolism in the muscles of rats that are given carbon source., Application of C7H8BrN

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 6911-87-1, formula is C7H8BrN, Name is 4-Bromo-N-methylaniline. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Synthetic Route of 6911-87-1.

Chen, Jiaming;Wang, Fang;Huang, Yanping;Jia, Xiaoqi;Zhuang, Dailin;Wan, Zhenyang;Li, Ziyuan research published 《 Remote carbamate-directed site-selective benzylic C-H oxygenation via synergistic copper/TEMPO catalysis at room temperature》, the research content is summarized as follows. Synthesis of benzylic C(sp³)-H oxygenation RNHC(O)R¹ (R = 4-butylphenyl, 4-butyl-2-fluorophenyl, 2,4-dibutyl-5-ethylphenyl, etc.; R¹ = hexyloxidanyl, Me, allyl, etc.) with water at room temperature through a ligand- and additive-free synergistic copper/TEMPO-catalyzed radical relay pathway with N-fluorobenzenesulfonimide (NFSI) as a terminal oxidant is disclosed. With the assistance of carbamate directing groups, this oxygenation takes place site-selectively at the para-positions of the directing groups when multiple benzyl sites are available in a substrates. Mechanistic studies reveal the crucial role of catalytic TEMPO as a recyclable SET reductant, as well as the significance of the combined synergistic catalysis and remote directing strategy to the excellent chemoselectivity and site-selectivity. It has also been demonstrated that this novel strategy is promising for future studies on C(sp³)-H functionalization.

6911-87-1, 4-Bromo-N-methylaniline is a aniline based compound known to exhibit mutagenic properties.
4-Bromo-N-methylaniline is a useful research compound. Its molecular formula is C7H8BrN and its molecular weight is 186.05 g/mol. The purity is usually 95%.
4-Bromophenylmethylamine is an organic compound that has anti-inflammatory properties and is used as a pharmaceutical. It belongs to the group of amines. The hydrolysis of 4-bromophenylmethylamine by hydrochloric acid produces phenol and bromamine (NHBr). The reaction system can be used to synthesize a number of compounds, including anilines, benzofurans, and other aromatic compounds. 4-Bromophenylmethylamine reacts with muscle tissue in a similar manner as acetaminophen does. This drug also has been shown to have significant effects on the energy metabolism in the muscles of rats that are given carbon source., Synthetic Route of 6911-87-1

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 6911-87-1, formula is C7H8BrN, Name is 4-Bromo-N-methylaniline, Category: bromides-buliding-blocks

Chen, Jian-Qiang;Tu, Xiaodong;Tang, Qi;Li, Ke;Xu, Liang;Wang, Siyu;Ji, Mingjuan;Li, Zhiming;Wu, Jie research published 《 Efficient access to aliphatic esters by photocatalyzed alkoxycarbonylation of alkenes with alkyloxalyl chlorides》, the research content is summarized as follows. A strategy to access aliphatic esters RC(O)OR¹ (R = 2-chloro-2-(4-methylphenyl)ethyl, 2-chloroheptyl, 2-chloro-2-cyclohexylethyl, 2-chloro-3-(2,3-dihydro-1H-indol-1-yl)-2-methyl-3-oxopropyl, etc.; R¹ = Et, 1,7,7-trimethylbicyclo[2.2.1]heptan-2-yl, 4-phenylbutyl, etc.) from olefins RH through a photocatalyzed alkoxycarbonylation reaction was reported. Alkyloxalyl chlorides R¹C(O)₂C(O)Cl, generated in situ from the corresponding alcs. R¹OH and oxalyl chloride, are engaged as alkoxycarbonyl radical fragments under photoredox catalysis. This transformation tolerates a broad scope of electron-rich and electron-deficient olefins and provides the corresponding β-chloro esters in good yields. Addnl., a formal β-selective alkene alkoxycarbonylation is developed. Moreover, a variety of oxindole-3-acetates I (R² = H, t-Bu, CN, me, etc.; R³ = Me, Bn; R⁴ = Me, Et, Bn, i-Pr), Et 2-(1-methyl-2-oxo-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)acetate, Et 2-(7-methyl-6-oxo-1,2,3,4,6,7-hexahydroazepino[3,2,1-hi]indol-7-yl)acetate, Et 2-(1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzo[g]indol-3-yl)acetate and furoindolines II are prepared in good to excellent yields. A more concise formal synthesis of (±)-physovenine is accomplished as well. With these strategies, a wide range of natural-product-derived olefins and alkyloxalyl chlorides are also successfully employed.

Category: bromides-buliding-blocks, 4-Bromo-N-methylaniline is a aniline based compound known to exhibit mutagenic properties.
4-Bromo-N-methylaniline is a useful research compound. Its molecular formula is C7H8BrN and its molecular weight is 186.05 g/mol. The purity is usually 95%.
4-Bromophenylmethylamine is an organic compound that has anti-inflammatory properties and is used as a pharmaceutical. It belongs to the group of amines. The hydrolysis of 4-bromophenylmethylamine by hydrochloric acid produces phenol and bromamine (NHBr). The reaction system can be used to synthesize a number of compounds, including anilines, benzofurans, and other aromatic compounds. 4-Bromophenylmethylamine reacts with muscle tissue in a similar manner as acetaminophen does. This drug also has been shown to have significant effects on the energy metabolism in the muscles of rats that are given carbon source., 6911-87-1.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 6911-87-1, formula is C7H8BrN, Name is 4-Bromo-N-methylaniline, Reference of 6911-87-1

Cao, Qiang;Zhang, Long-Long;Zhou, Chang;He, Jing-Hui;Marcomini, Antonio;Lu, Jian-Mei research published 《 Covalent organic framework-supported Zn single atom catalyst for highly efficient N-formylation of amines with CO₂ under mild conditions》, the research content is summarized as follows. Transformation of CO₂ into value-added chems. with efficient and recyclable catalyst is an effective way to reduce carbon emissions. It is valuable to develop an efficient catalyst that can promote the N-formylation reaction under mild conditions with a high activity and excellent recyclability. Single atom catalysts (SACs) possess ultimate atom utilization efficiency and outstanding catalytic performance. Herein, we synthesize Zn SACs (Zn-TpPa) anchored on a COF (TpPa-1) using a facile solution method. Catalyzed by Zn-TpPa, CO₂ and N-methylamine are transformed into N-methylformanilide under mild reaction conditions with a TOF of 17,155 h^-1, which is the highest among all reported recyclable Zn-based catalysts. Zn-TpPa can also catalyze N-formylation of many other amines with excellent yields. The higher reactivity was attributable to the well-dispersed Zn active sites on COF and outstanding adsorption of CO₂ owing to high surface area of COF. Our research provides a facile method for constructing SACs as well as an effective pathway for CO₂ transformation and environmental protection.

6911-87-1, 4-Bromo-N-methylaniline is a aniline based compound known to exhibit mutagenic properties.
4-Bromo-N-methylaniline is a useful research compound. Its molecular formula is C7H8BrN and its molecular weight is 186.05 g/mol. The purity is usually 95%.
4-Bromophenylmethylamine is an organic compound that has anti-inflammatory properties and is used as a pharmaceutical. It belongs to the group of amines. The hydrolysis of 4-bromophenylmethylamine by hydrochloric acid produces phenol and bromamine (NHBr). The reaction system can be used to synthesize a number of compounds, including anilines, benzofurans, and other aromatic compounds. 4-Bromophenylmethylamine reacts with muscle tissue in a similar manner as acetaminophen does. This drug also has been shown to have significant effects on the energy metabolism in the muscles of rats that are given carbon source., Reference of 6911-87-1

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 6911-87-1, formula is C7H8BrN, The most pervasive is the naturally produced bromomethane. Recommanded Product: 4-Bromo-N-methylaniline

Bonnefoy, Clemence;Chefdeville, Emmanuel;Tourvieille, Christian;Panossian, Armen;Hanquet, Gilles;Leroux, Frederic;Toulgoat, Fabien;Billard, Thierry research published 《 Study of Carbamoyl Fluoride: Synthesis, Properties and Applications》, the research content is summarized as follows. In this study, the little-explored carbamoyl fluorides have been studied in order to bring relevant information for their application to the community of chemists. A new easy, safe, inexpensive, and metal-free synthesis method is also described. Finally, a potential use in radiochem. through a ¹⁸F/¹⁹F isotopic exchange is demonstrated.

Recommanded Product: 4-Bromo-N-methylaniline, 4-Bromo-N-methylaniline is a aniline based compound known to exhibit mutagenic properties.
4-Bromo-N-methylaniline is a useful research compound. Its molecular formula is C7H8BrN and its molecular weight is 186.05 g/mol. The purity is usually 95%.
4-Bromophenylmethylamine is an organic compound that has anti-inflammatory properties and is used as a pharmaceutical. It belongs to the group of amines. The hydrolysis of 4-bromophenylmethylamine by hydrochloric acid produces phenol and bromamine (NHBr). The reaction system can be used to synthesize a number of compounds, including anilines, benzofurans, and other aromatic compounds. 4-Bromophenylmethylamine reacts with muscle tissue in a similar manner as acetaminophen does. This drug also has been shown to have significant effects on the energy metabolism in the muscles of rats that are given carbon source., 6911-87-1.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 6911-87-1, formula is C7H8BrN, Name is 4-Bromo-N-methylaniline. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Computed Properties of 6911-87-1.

Bourriquen, Florian;Rockstroh, Nils;Bartling, Stephan;Junge, Kathrin;Beller, Matthias research published 《 Manganese-Catalysed Deuterium Labelling of Anilines and Electron-Rich (Hetero)Arenes》, the research content is summarized as follows. Here, a new class of heterogeneous catalysts was reported for practical deuterium incorporation in anilines, phenols, and heterocyclic substrates. The optimal material can be conveniently synthesized and allows for high deuterium incorporation using deuterium oxide as isotope source. This new catalyst was fully characterized and successfully applied to the labeling of natural products as well as marketed drugs.

6911-87-1, 4-Bromo-N-methylaniline is a aniline based compound known to exhibit mutagenic properties.
4-Bromo-N-methylaniline is a useful research compound. Its molecular formula is C7H8BrN and its molecular weight is 186.05 g/mol. The purity is usually 95%.
4-Bromophenylmethylamine is an organic compound that has anti-inflammatory properties and is used as a pharmaceutical. It belongs to the group of amines. The hydrolysis of 4-bromophenylmethylamine by hydrochloric acid produces phenol and bromamine (NHBr). The reaction system can be used to synthesize a number of compounds, including anilines, benzofurans, and other aromatic compounds. 4-Bromophenylmethylamine reacts with muscle tissue in a similar manner as acetaminophen does. This drug also has been shown to have significant effects on the energy metabolism in the muscles of rats that are given carbon source., Computed Properties of 6911-87-1

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 6911-87-1, formula is C7H8BrN, The most pervasive is the naturally produced bromomethane. Recommanded Product: 4-Bromo-N-methylaniline

Bonnefoy, Clemence;Chefdeville, Emmanuel;Tourvieille, Christian;Panossian, Armen;Hanquet, Gilles;Leroux, Frederic;Toulgoat, Fabien;Billard, Thierry research published 《 Study of Carbamoyl Fluoride: Synthesis, Properties and Applications》, the research content is summarized as follows. In this study, the little-explored carbamoyl fluorides have been studied in order to bring relevant information for their application to the community of chemists. A new easy, safe, inexpensive, and metal-free synthesis method is also described. Finally, a potential use in radiochem. through a ¹⁸F/¹⁹F isotopic exchange is demonstrated.

Recommanded Product: 4-Bromo-N-methylaniline, 4-Bromo-N-methylaniline is a aniline based compound known to exhibit mutagenic properties.
4-Bromo-N-methylaniline is a useful research compound. Its molecular formula is C7H8BrN and its molecular weight is 186.05 g/mol. The purity is usually 95%.
4-Bromophenylmethylamine is an organic compound that has anti-inflammatory properties and is used as a pharmaceutical. It belongs to the group of amines. The hydrolysis of 4-bromophenylmethylamine by hydrochloric acid produces phenol and bromamine (NHBr). The reaction system can be used to synthesize a number of compounds, including anilines, benzofurans, and other aromatic compounds. 4-Bromophenylmethylamine reacts with muscle tissue in a similar manner as acetaminophen does. This drug also has been shown to have significant effects on the energy metabolism in the muscles of rats that are given carbon source., 6911-87-1.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary