Category: 6825-20-3

《Synthesis of novel multifunctional carbazole-based molecules and their thermal, electrochemical and optical properties》 was written by Altinolcek, Nuray; Battal, Ahmet; Tavasli, Mustafa; Peveler, William J.; Yu, Holly A.; Skabara, Peter J.. Name: 3,6-Dibromo-9H-carbazole And the article was included in Beilstein Journal of Organic Chemistry in 2020. The article conveys some information:

Two novel carbazole-based compounds I [R = 4-formyl, 5-formyl] were synthesized as potential candidates for application in organic electronics. The materials were fully characterised by NMR spectroscopy, mass spectrometry, FTIR, thermogravimetric anal., differential scanning calorimetry, cyclic voltammetry, and absorption and emission spectroscopy. Compounds I, both of which were amorphous solids, were stable up to 291°C and 307°C, resp. Compounds I showed three distinctive absorption bands: high and mid energy bands due to locally excited (LE) transitions and low energy bands due to intramol. charge transfer (ICT) transitions. In dichloromethane solutions compounds I gave emission maxima at 561 nm and 482 nm with quantum efficiencies of 5.4% and 97.4% ± 10%, resp. At pos. potential, compounds I gave two different oxidation peaks, resp.: quasi-reversible at 0.55 V and 0.71 V, and reversible at 0.84 V and 0.99 V. At neg. potentials, compounds I only exhibited an irreversible reduction peak at -1.86 V and -1.93 V, resp. The experimental process involved the reaction of 3,6-Dibromo-9H-carbazole(cas: 6825-20-3Name: 3,6-Dibromo-9H-carbazole)

3,6-Dibromo-9H-carbazole(cas: 6825-20-3) is used as a pharmaceutical intermediate, and also an important intermediate of synthesizing optoelectronic materials. It has been used as a reagent in the synthesis of P7C3-A20 which is a potent neuroprotective agent.Name: 3,6-Dibromo-9H-carbazole

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Molecular Diffusion in a Flexible Mesoporous Metal-Organic Framework over the Course of Structural Contraction》 was written by Walenszus, Francesco; Bon, Volodymyr; Evans, Jack D.; Kaskel, Stefan; Dvoyashkin, Muslim. SDS of cas: 6825-20-3 And the article was included in Journal of Physical Chemistry Letters in 2020. The article conveys some information:

In situ 1H pulsed field gradient (PFG) NMR was used to investigate the mol. diffusion of n-butane in the pores of the flexible metal-organic framework DUT-49(Cu) at 298 K at different pore loadings, including pressure ranges below and above the neg. gas adsorption (NGA) transition caused by structural contraction of the material. Supported by mol. dynamics simulations, the investigation provided crucial insight into confined diffusion within a highly flexible pore environment. The self-diffusion coefficients were derived from the experiment and compared with simulations, capturing the diffusion during n-butane adsorption and desorption. This complementary approach has yielded exptl. characterization of mol. diffusion mechanisms during the unique process of NGA. This includes the observation of a 4-fold decrease of diffusivity within a less than 2 kPa gas pressure variation, corresponding to the NGA transition point. In addition to this study using 3,6-Dibromo-9H-carbazole, there are many other studies that have used 3,6-Dibromo-9H-carbazole(cas: 6825-20-3SDS of cas: 6825-20-3) was used in this study.

3,6-Dibromo-9H-carbazole(cas: 6825-20-3) is used as a pharmaceutical intermediate, and also an important intermediate of synthesizing optoelectronic materials. It has been used as a reagent in the synthesis of P7C3-A20 which is a potent neuroprotective agent.SDS of cas: 6825-20-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Swarbrick, Crystall; Zogali, Vasiliki; Chan, Kitti Wing Ki; Kiousis, Dimitrios; Gwee, Chin Piaw; Wang, Sai; Lescar, Julien; Luo, Dahai; von Itzstein, Mark; Matsoukas, Minos-Timotheos; Panagiotakopoulos, George; Vasudevan, Subhash G.; Rassias, Gerasimos published their research in European Journal of Medicinal Chemistry in 2021. The article was titled 《Amidoxime prodrugs convert to potent cell-active multimodal inhibitors of the dengue virus protease》.Reference of 3,6-Dibromo-9H-carbazole The article contains the following contents:

The flavivirus genus of the Flaviviridae family comprises Dengue, Zika and West-Nile viruses which constitute unmet medical needs as neither appropriate antivirals nor safe vaccines are available. The dengue NS2BNS3 protease is one of the most promising validated targets for developing a dengue treatment however reported protease inhibitors suffer from toxicity and cellular inefficacy. Here we report SAR on our previously reported Zika-active carbazole scaffold, culminating in prodrug compound SP-471P (EC50 1.10μM, CC50 > 100μM) that generates SP-471 (I → II); one of the most potent, non-cytotoxic and cell-active protease inhibitors described in the dengue literature. In cell-based assays, SP-471P leads to inhibition of viral RNA replication and complete abolishment of infective viral particle production even when administered 6 h post-infection. Mechanistically, SP-471 appears to inhibit both normal intermol. protease processes and intramol. cleavage events at the NS2BNS3 junction, as well as at NS3 internal sites, all critical for virus replication. These render SP-471 a unique to date multimodal inhibitor of the dengue protease. The results came from multiple reactions, including the reaction of 3,6-Dibromo-9H-carbazole(cas: 6825-20-3Reference of 3,6-Dibromo-9H-carbazole)

3,6-Dibromo-9H-carbazole(cas: 6825-20-3) is used as a reagent in the synthesis of P7C3-A20 which is a potent neuroprotective agent. And it has been used in the preparation of N-(2-hydroxyethyl)-3,6-dibromocarbazole.Reference of 3,6-Dibromo-9H-carbazole

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Fiankor, Christian; Nyakuchena, James; Khoo, Rebecca Shu Hui; Zhang, Xu; Hu, Yuchen; Yang, Sizhuo; Huang, Jier; Zhang, Jian published their research in Journal of the American Chemical Society in 2021. The article was titled 《Symmetry-Guided Synthesis of N,N′-Bicarbazole and Porphyrin-Based Mixed-Ligand Metal-Organic Frameworks: Light Harvesting and Energy Transfer》.COA of Formula: C12H7Br2N The article contains the following contents:

In the past decades, many attempts have been made to mimic the energy transfer (EnT) in photosynthesis, a key process occurring in nature that is of fundamental significance in solar fuels and sustainable energy. Metal-organic frameworks (MOFs), an emerging class of porous crystalline materials self-assembled from organic linkers and metal or metal cluster nodes, offer an ideal platform for the exploration of directional EnT phenomena. However, placing energy donor and acceptor moieties within the same framework with an atomistic precision appears to be a major synthesis challenge. In this work, we report the design and synthesis of a highly porous and photoactive N,N′-bicarbazole- and porphyrin-based mixed-ligand MOF, namely, NPF-500-H2TCPP (NPF = Nebraska porous framework; H2TCPP = meso-tetrakis(4-carboxyphenyl)porphyrin), where the secondary ligand H2TCPP is incorporated precisely through the open metal sites of the equatorial plane of the octahedron cage resulting from the underlying (4,8) connected network of NPF-500. The efficient EnT process from N,N′-bicarbazole to porphyrin in NPF-500-H2TCPP was captured by time-resolved spectroscopy and exemplified by photocatalytic oxidation of thioanisole. These results demonstrate not only the capability of NPF-500 as the scaffold to precisely arrange the donor-acceptor assembly for the EnT process but also the potential to directly utilize the EnT process for photocatalytic applications.3,6-Dibromo-9H-carbazole(cas: 6825-20-3COA of Formula: C12H7Br2N) was used in this study.

3,6-Dibromo-9H-carbazole(cas: 6825-20-3) is used as a reagent in the synthesis of P7C3-A20 which is a potent neuroprotective agent. And it has been used in the preparation of N-(2-hydroxyethyl)-3,6-dibromocarbazole.COA of Formula: C12H7Br2N

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Photo-regulated supramolecular star with a pillar[6]arene-coated metal-organic polyhedron (MOP) core》 was written by Hao, Xiang; Leng, Zejian; Sun, Dan; Peng, Feng; Yasin, Akram. SDS of cas: 6825-20-3 And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2020. The article conveys some information:

Authors herein report a 12-armed photo-responsive supramol. star centered by a pillar[6]arene-coated M6L12 metal-organic polyhedron (MOP) via a core-first approach. In the experiment, the researchers used many compounds, for example, 3,6-Dibromo-9H-carbazole(cas: 6825-20-3SDS of cas: 6825-20-3)

3,6-Dibromo-9H-carbazole(cas: 6825-20-3) is used as a pharmaceutical intermediate, and also an important intermediate of synthesizing optoelectronic materials. It has been used in the preparation of N-(2-hydroxyethyl)-3,6-dibromocarbazole.SDS of cas: 6825-20-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Qi, Zhi-Chao; Lou, Qin-Xin; Niu, Yuan; Yang, Shang-Dong published their research in Chemical Communications (Cambridge, United Kingdom) in 2021. The article was titled 《Temporary (P=O) directing group enabled carbazole ortho arylation via palladium catalysis》.Reference of 3,6-Dibromo-9H-carbazole The article contains the following contents:

A palladium-catalyzed, temporary P(O) directing group assisted C-H bond arylation of carbazoles was achieved. The release of the directing group occurred spontaneously in the reaction and the mechanistic studies indicated that acid was essential for N-P bond cleavage. The experimental part of the paper was very detailed, including the reaction process of 3,6-Dibromo-9H-carbazole(cas: 6825-20-3Reference of 3,6-Dibromo-9H-carbazole)

3,6-Dibromo-9H-carbazole(cas: 6825-20-3) is used as a pharmaceutical intermediate, and also an important intermediate of synthesizing optoelectronic materials. It has been used as a reagent in the synthesis of P7C3-A20 which is a potent neuroprotective agent.Reference of 3,6-Dibromo-9H-carbazole

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Recommanded Product: 3,6-Dibromo-9H-carbazoleIn 2022 ,《Carbazole-siloxane based polymers for the selective detection of 4-nitrophenol and Fe3+》 was published in Journal of Photochemistry and Photobiology, A: Chemistry. The article was written by Wang, Aijing; Tian, Minggang; Zuo, Yujing; Gou, Zhiming. The article contains the following contents:

Silicone-containing polymers have broad application prospects in the detection of many analytes due to their unique fluorescence properties. Environmental pollutants are very complex, which have prompted researchers to explore different detection methods. In this report, two kinds of polymers were synthesized via Heck-reaction between tetramethyltetravinylcyclotetrasiloxane (Dvi4) and carbazole derivatives The polymers showed excellent fluorescent properties and exhibited high sensitivity to 4-nitrophenol (4-NP) and Fe3+ in solution Furthermore, the polymers still showed high sensitivity for Fe3+ in living cells. We estimate that the cyclic structure of Dvi4 and carbazole structure will serve as responsive sites for Fe3+ and 4-NP, resp. The frontier MOs of polymers were calculated by Materials Studio and the effect of the cyclic structure of Dvi4 on their responsiveness had been discussed. The design idea of the polymer sensors can provide a new direction for the synthesis of multi-response polymer fluorescent probes. In the experiment, the researchers used 3,6-Dibromo-9H-carbazole(cas: 6825-20-3Recommanded Product: 3,6-Dibromo-9H-carbazole)

3,6-Dibromo-9H-carbazole(cas: 6825-20-3) is used as a pharmaceutical intermediate, and also an important intermediate of synthesizing optoelectronic materials. It has been used in the preparation of N-(2-hydroxyethyl)-3,6-dibromocarbazole.Recommanded Product: 3,6-Dibromo-9H-carbazole

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《One-pot synthesis of a white-light emissive bichromophore operated by aggregation-induced dual emission (AIDE) and partial energy transfer》 was written by Denissen, Melanie; Hannen, Ricarda; Itskalov, Dana; Biesen, Lukas; Nirmalananthan-Budau, Nithiya; Hoffmann, Katrin; Reiss, Guido J.; Resch-Genger, Ute; Mueller, Thomas J. J.. Synthetic Route of C12H7Br2NThis research focused onwhite light fluorescence bichromophore aggregation induced emission energy transfer. The article conveys some information:

Merocyanine-triarylamine bichromophores are readily synthesized by sequentially Pd-catalyzed insertion-alkynylation-Michael-Suzuki four-component reactions. White-light emissive systems form upon aggregation in 1 : 99 and 0.1 : 99.9 vol% CH2Cl2-cyclohexane mixtures, ascribed to aggregation-induced dual emission (AIDE) in combination with partial energy transfer between both chromophore units as supported by spectroscopic studies. The experimental part of the paper was very detailed, including the reaction process of 3,6-Dibromo-9H-carbazole(cas: 6825-20-3Synthetic Route of C12H7Br2N)

3,6-Dibromo-9H-carbazole(cas: 6825-20-3) is used as a pharmaceutical intermediate, and also an important intermediate of synthesizing optoelectronic materials. It has been used in the preparation of N-(2-hydroxyethyl)-3,6-dibromocarbazole.Synthetic Route of C12H7Br2N

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2019,Chemical Communications (Cambridge, United Kingdom) included an article by Kawano, Shin-ichiro; Kawada, Sae; Kitagawa, Yasutaka; Teramoto, Rena; Nakano, Masayoshi; Tanaka, Kentaro. Quality Control of 3,6-Dibromo-9H-carbazole. The article was titled 《Near-infrared absorption by intramolecular charge-transfer transition in 5,10,15,20-tetra(N-carbazolyl)porphyrin through protonation》. The information in the text is summarized as follows:

A porphyrin coupled quadruply with N-carbazolyl groups at the meso positions was synthesized. Because of the electron-withdrawing nature of the carbazole units at the porphyrin center, the tetra(N-carbazolyl)porphyrin and the protonated derivative display unique absorption bands derived from intramol. charge-transfer transition from the carbazoles to the porphyrin moiety. After reading the article, we found that the author used 3,6-Dibromo-9H-carbazole(cas: 6825-20-3Quality Control of 3,6-Dibromo-9H-carbazole)

3,6-Dibromo-9H-carbazole(cas: 6825-20-3) is used as a pharmaceutical intermediate, and also an important intermediate of synthesizing optoelectronic materials. It has been used as a reagent in the synthesis of P7C3-A20 which is a potent neuroprotective agent.Quality Control of 3,6-Dibromo-9H-carbazole

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Bera, Sourav Sekhar; Bahukhandi, Srishti Ballabh; Empel, Claire; Koenigs, Rene M. published their research in Chemical Communications (Cambridge, United Kingdom) in 2021. The article was titled 《Catalyst-controlled site-selective N-H and C3-arylation of carbazole via carbene transfer reactions》.Application In Synthesis of 3,6-Dibromo-9H-carbazole The article contains the following contents:

A site-selective direct arylation reaction of carbazole and other N-heterocycles with diazo-naphthalen-2(1H)-ones was developed. While Au(I)-NHC catalysts led to selective C3-arylation, palladium acetate allowed for selective N-H arylation, displaying complete site-selectivity each. To show the applicability of these arylation reactions, one-pot, two-fold diarylation reactions of carbazole were demonstrated. In the experiment, the researchers used 3,6-Dibromo-9H-carbazole(cas: 6825-20-3Application In Synthesis of 3,6-Dibromo-9H-carbazole)

3,6-Dibromo-9H-carbazole(cas: 6825-20-3) is used as a reagent in the synthesis of P7C3-A20 which is a potent neuroprotective agent. And it has been used in the preparation of N-(2-hydroxyethyl)-3,6-dibromocarbazole.Application In Synthesis of 3,6-Dibromo-9H-carbazole

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary