Category: 6825-20-3

HPLC of Formula: 6825-20-3In 2020 ,《Proton Transfer Can Govern Regioselectivity Assisted by Iron Catalysis》 appeared in iScience. The author of the article were Li, Yudong; Fu, Liyan; Jiang, Xiaolin; Zhao, Dongmei; Wang, Hui-Fang; Xia, Chungu; Li, Yuehui. The article conveys some information:

Ortho-selective aromatic C-H functionalization is frequently used in organic synthesis and chem./pharmaceutical industries. However, this reaction relies heavily on the use of directing groups suffering from limited substrate scope and extra steps to put on and remove the directing/protecting groups. Herein authors present the previously neglected concept that enables good to nearly complete selective ortho position. Proton transfer was utilized to tune the electron d. on the aryl ring and determine the positional selectivity of electrophilic substitution. Consistently with deuteration experiments and DFT studies, this work demonstrates that acid-promoted proton transfer directs accelerated ortho-selective halogenation of NH/OH contained aromatic amines/phenols with excellent selectivity (>40 examples; up to 98:2 ortho/para selectivity). The application potential of this Fe-catalyzed method is demonstrated by the convenient synthesis of three alkaloids and tizanidine. This report raises the possibility that proton transfer could serve as the basis of developing new selective C-H functionalization reactions. After reading the article, we found that the author used 3,6-Dibromo-9H-carbazole(cas: 6825-20-3HPLC of Formula: 6825-20-3)

3,6-Dibromo-9H-carbazole(cas: 6825-20-3) is used as a pharmaceutical intermediate, and also an important intermediate of synthesizing optoelectronic materials. It has been used in the preparation of N-(2-hydroxyethyl)-3,6-dibromocarbazole.HPLC of Formula: 6825-20-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Chen, Si; Behera, Nibedita; Yang, Chao; Dong, Qiubing; Zheng, Baishu; Li, Yingying; Tang, Qi; Wang, Zhaoxu; Wang, Yanqing; Duan, Jingui published an article in 2021. The article was titled 《A chemically stable nanoporous coordination polymer with fixed and free Cu2+ ions for boosted C2H2/CO2 separation》, and you may find the article in Nano Research.Recommanded Product: 6825-20-3 The information in the text is summarized as follows:

Safely and highly selective acetylene (C2H2) capture is a great challenge, because of its highly explosive nature, as well as its nearly similar mol. size and b.p. toward the main impurity of carbon dioxide (CO2). Adsorption separation has shown a promising future. Herein, a new nanoporous coordination polymer (PCP) adsorbent with fixed and free Cu ions (termed NTU-66-Cu) was prepared through post-synthetic approach via cation exchanging from the pristine NTU-66, an anionic framework with new 3, 4, 6-c topol. and two kinds of cages. The NTU-66-Cu shows significantly improved C2H2/CO2 selectivity from 6 to 32 (volume/volume: 1/1) or 4 to 42 (volume/volume: 1/4) at low pressure under 298 K, along with enhanced C2H2 capacity (from 89.22 to 111.53 cm3·g-1). More importantly, this observation was further validated by d. functional theory (DFT) calculations and breakthrough experiments under continuous and dynamic conditions. Further, the excellent chem. stability enables this adsorbent to achieve recycle C2H2/CO2 separation without loss of C2H2 capacity. [graphic not available: see fulltext] In the experiment, the researchers used 3,6-Dibromo-9H-carbazole(cas: 6825-20-3Recommanded Product: 6825-20-3)

3,6-Dibromo-9H-carbazole(cas: 6825-20-3) is used as a pharmaceutical intermediate, and also an important intermediate of synthesizing optoelectronic materials. It has been used as a reagent in the synthesis of P7C3-A20 which is a potent neuroprotective agent.Recommanded Product: 6825-20-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Quality Control of 3,6-Dibromo-9H-carbazoleIn 2022 ,《Functionalization of Biphenylcarbazole (CBP) with Siloxane-Hybrid Chains for Solvent-Free Liquid Materials》 was published in Molecules. The article was written by Shaya, Janah; Correia, Gabriel; Heinrich, Benoit; Ribierre, Jean-Charles; Polychronopoulou, Kyriaki; Mager, Loic; Mery, Stephane. The article contains the following contents:

Herein the synthesis of siloxane-functionalized CBP mols. (4,4′-bis(carbazole)-1,1′-biphenyl) for liquid optoelectronic applications was reported. The room-temperature liquid state was obtained through a convenient functionalization of the mols. with heptamethyltrisiloxane chains via hydrosilylation of alkenyl spacers. The synthesis comprised screening of metal-catalyzed methodologies to introduce alkenyl linkers into carbazoles (Stille and Suzuki Miyaura cross-couplings), incorporated the alkenylcarbazoles to dihalobiphenyls (Ullmann coupling), and finally introduced the siloxane chains. The used conditions allowed the synthesis of the target compounds, despite the high reactivity of the alkenyl moieties bound to π-conjugated systems toward undesired side reactions such as polymerization, isomerization, and hydrogenation. The features of these solvent-free liquid CBP derivatives made them potentially interesting for fluidic optoelectronic applications.3,6-Dibromo-9H-carbazole(cas: 6825-20-3Quality Control of 3,6-Dibromo-9H-carbazole) was used in this study.

3,6-Dibromo-9H-carbazole(cas: 6825-20-3) is used as a pharmaceutical intermediate, and also an important intermediate of synthesizing optoelectronic materials. It has been used in the preparation of N-(2-hydroxyethyl)-3,6-dibromocarbazole.Quality Control of 3,6-Dibromo-9H-carbazole

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Formula: C12H7Br2NIn 2022 ,《Occurrence and distribution of polyhalogenated carbazoles in eastern Tibetan Plateau soils along the slope of Mt. Qionglai》 appeared in Chemosphere. The author of the article were Liu, Mingkai; Huang, Longhua; Li, Xiaoshuang; Liu, Fei; Zhang, Wei; Wang, Zhe; Xu, Yan; Ke, Runhui; He, Hongping; Lou, Yinghua. The article conveys some information:

Polyhalogenated carbazoles (PHCZs), are considered as potential persistent organic pollutants (POPs), which have been frequently detected in the environment. However, the altitudinal distribution characteristics and possible sources of PHCZs in high mountain soils are still unknown. The present study was the first to analyze PHCZs in soil samples collected along the eastern slope of Mt. Qionglai (MQ), the east edge of the Tibetan Plateau. The concentration of ΣPHCZs (based on dry weight) ranges from 14.4 to 107 ng/g (median value of 40.9), which was at high end of the range reported in soils and sediments to date in the literature. The composition profiles of PHCZs in the soils of MQ were dominated by 3,6-dichlorocarbazole (36-CCZ), 3-chlorocarbazole (3-CCZ), and 2-bromocarbazole (2-BCZ). The mean TOC-normalized concentrations of ΣPHCZs in soil samples from below-treeline (2092 ng/g TOC) were higher than those from alpine meadow (1124 ng/g TOC), probably due to the forest filter effect. The decreasing trend of the PHCZs TOC-normalized concentrations with altitude shows that accumulation of PHCZs from the alpine meadow samples was not affected by the mountain cold-trapping effect. Significantly pos. correlations were observed between the concentrations of more than half of detected PHCZ congeners and TOC. In addition, PHCZs show the potential to represent a class of POPs with the frequent occurrence and wide distribution, as the abundance and environmental behavior of PHCZs are similar to some POPs in MQ. In the experimental materials used by the author, we found 3,6-Dibromo-9H-carbazole(cas: 6825-20-3Formula: C12H7Br2N)

3,6-Dibromo-9H-carbazole(cas: 6825-20-3) is used as a pharmaceutical intermediate, and also an important intermediate of synthesizing optoelectronic materials. It has been used in the preparation of N-(2-hydroxyethyl)-3,6-dibromocarbazole.Formula: C12H7Br2N

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《1,6-Aza-Michael addition of para-quinone methides with N-heterocycles catalyzed by Zn(OTf)2: A regioselective approach to N-diarylmethyl-substituted heterocycles》 was written by Guin, Soumitra; Saha, Hemonta K.; Patel, Ashvani K.; Gudimella, Santosh K.; Biswas, Subhankar; Samanta, Sampak. Quality Control of 3,6-Dibromo-9H-carbazole And the article was included in Tetrahedron in 2020. The article conveys some information:

An efficient Zn(OTf)2-catalyzed regioselective C-N bond making reaction between a bunch of aryl/heteroaryl-substituted para-quinone methides as ideal 1,6-acceptors and various aromatic/non-aromatic aza-heterocycles bearing N-H moiety namely carbazoles, pyrazoles, indazole, benzotriazole and saccharin is reported. This 1,6-aza-Michael technique delivers predominantly N1-diarylmethyl-substituted heterocyclic scaffolds bearing a valuable phenolic moiety in good to high yields with an excellent regioselectivity. Furthermore, this LUMO lowering catalytic system allows different kinds of useful functionalities and excels with broad substrates under mild conditions. Importantly, control experiments suggested that N2-adducts of indazole, benzotriazole and 3-Me pyrazole as minor isomers were progressively converted into N1-adducts during the reaction via a retro-aza-Michael reaction triggered by Zn(OTf)2, offering excellent regioselectivities of the products. In the part of experimental materials, we found many familiar compounds, such as 3,6-Dibromo-9H-carbazole(cas: 6825-20-3Quality Control of 3,6-Dibromo-9H-carbazole)

3,6-Dibromo-9H-carbazole(cas: 6825-20-3) is used as a pharmaceutical intermediate, and also an important intermediate of synthesizing optoelectronic materials. It has been used as a reagent in the synthesis of P7C3-A20 which is a potent neuroprotective agent.Quality Control of 3,6-Dibromo-9H-carbazole

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Xu, Hongyan; Zheng, Minggang; Wang, Ling; Zhao, Wucai; Hua, Yi; Fang, Lidan; Liu, Aifeng; Zhao, Zongshan published an article in 2021. The article was titled 《High throughput extraction strategy for simultaneous analysis of 19 tetrabromobisphenol A and halogenated carbazole analogs in seafood》, and you may find the article in Food Chemistry.SDS of cas: 6825-20-3 The information in the text is summarized as follows:

Tetrabromobisphenol A (TBBPA), halogenated carbazole (HCZ), and their analogs are the emerging pollutants invading the marine environment. So far, a few methods have been reported for the simultaneous anal. of these pollutants due to their large polarity difference. In this study, an effective extraction and cleanup strategy was developed for the simultaneous determination of 19 TBBPA and HCZ congeners in seafood. The 19 analytes could be directly analyzed through high performance liquid chromatog. after ultrasonic extraction (methanol, duplicate Et acetate-acetone (1:1, volume/volume)) and gel permeation chromatog. cleanup. The acceptable spike-recoveries were within 65.7-118.3%; the precision was intra-/inter-day RSDs: 0.0-6.7%/0.0-8.5%; and the matrix effects were between -14.1% and 12.4%. The detection limits and quantification limits were 0.002-0.014 and 0.020-0.200 μg g-1 dw, resp. Addnl., this method successfully analyzed the seafood samples and the concentrations of these analytes were in range of nd-5.4 μg g-1 dw. In addition to this study using 3,6-Dibromo-9H-carbazole, there are many other studies that have used 3,6-Dibromo-9H-carbazole(cas: 6825-20-3SDS of cas: 6825-20-3) was used in this study.

3,6-Dibromo-9H-carbazole(cas: 6825-20-3) is used as a pharmaceutical intermediate, and also an important intermediate of synthesizing optoelectronic materials. It has been used as a reagent in the synthesis of P7C3-A20 which is a potent neuroprotective agent.SDS of cas: 6825-20-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2019,Dyes and Pigments included an article by Zhao, Fei; Chen, Zhao; Fan, Congbin; Liu, Gang; Pu, Shouzhi. Recommanded Product: 6825-20-3. The article was titled 《Aggregation-induced emission (AIE)-active highly emissive novel carbazole-based dyes with various solid-state fluorescence and reversible mechanofluorochromism characteristics》. The information in the text is summarized as follows:

Three new carbazole-based fluorescent mols. 1-3 functionalized with tetraphenylethene were successfully synthesized, and these compounds have high thermal stability, and they exhibited different fluorescence in solid states with the superior luminescence quantum yields of 99.04% (1), 98.90% (2) and 39.83% (3). Their aggregation-induced behaviors were explored by the study of photoluminescence spectroscopy. Luminogens 1-3 exhibited remarkable aggregation-induced emission effect. Also, their distinct mech. stimulus-responsive fluorescence characteristics were also surveyed by solid-state photoluminescence spectroscopy. The various emitting colors of these luminogens could be changed into the same green, and the repeatabilities of their mechanochromic luminescence behaviors were outstanding, and the powder x-ray diffraction results indicated that the reversible conversion from a crystalline to an amorphous state was responsible for the obvious mechanofluorochromism phenomena of compounds 1-3. This work will be valuable for the exploitation of mech.-force sensors with typical aggregation-induced emission feature. In the experiment, the researchers used 3,6-Dibromo-9H-carbazole(cas: 6825-20-3Recommanded Product: 6825-20-3)

3,6-Dibromo-9H-carbazole(cas: 6825-20-3) is used as a reagent in the synthesis of P7C3-A20 which is a potent neuroprotective agent. And it has been used in the preparation of N-(2-hydroxyethyl)-3,6-dibromocarbazole.Recommanded Product: 6825-20-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2019,Dyes and Pigments included an article by Zhao, Fei; Chen, Zhao; Fan, Congbin; Liu, Gang; Pu, Shouzhi. Recommanded Product: 6825-20-3. The article was titled 《Aggregation-induced emission (AIE)-active highly emissive novel carbazole-based dyes with various solid-state fluorescence and reversible mechanofluorochromism characteristics》. The information in the text is summarized as follows:

Three new carbazole-based fluorescent mols. 1-3 functionalized with tetraphenylethene were successfully synthesized, and these compounds have high thermal stability, and they exhibited different fluorescence in solid states with the superior luminescence quantum yields of 99.04% (1), 98.90% (2) and 39.83% (3). Their aggregation-induced behaviors were explored by the study of photoluminescence spectroscopy. Luminogens 1-3 exhibited remarkable aggregation-induced emission effect. Also, their distinct mech. stimulus-responsive fluorescence characteristics were also surveyed by solid-state photoluminescence spectroscopy. The various emitting colors of these luminogens could be changed into the same green, and the repeatabilities of their mechanochromic luminescence behaviors were outstanding, and the powder x-ray diffraction results indicated that the reversible conversion from a crystalline to an amorphous state was responsible for the obvious mechanofluorochromism phenomena of compounds 1-3. This work will be valuable for the exploitation of mech.-force sensors with typical aggregation-induced emission feature. In the experiment, the researchers used 3,6-Dibromo-9H-carbazole(cas: 6825-20-3Recommanded Product: 6825-20-3)

3,6-Dibromo-9H-carbazole(cas: 6825-20-3) is used as a reagent in the synthesis of P7C3-A20 which is a potent neuroprotective agent. And it has been used in the preparation of N-(2-hydroxyethyl)-3,6-dibromocarbazole.Recommanded Product: 6825-20-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

The author of 《New insight into the formation of polyhalogenated carbazoles: Aqueous chlorination of residual carbazole under bromide condition in drinking water》 were Wang, Guowei; Yang, Jiakuan; Gao, Shixiang; Hou, Huijie; Xiao, Keke; Hu, Jingping; Liang, Sha; Liu, Bingchuan. And the article was published in Water Research in 2019. Reference of 3,6-Dibromo-9H-carbazole The author mentioned the following in the article:

Although polyhalogenated carbazoles (PHCZs) have been increasingly delected in aquatic environments, studies on their source and formation are extremely scarce. After investigation of PHCZs and carbazole in drinking water, an overlooked formation route of chloro/bromo-CZs was now proposed as aqueous chlorination of residual carbazole under bromide condition. Four groups of PHCZ, including mono-, di-, tri-, and tetra-halogenated groups, were identified in chlorinated drinking water, and the mechanism of the formation of the four groups of PHCZs was proposed. Twenty-six PHCZ congeners, including chloro-, bromo-, and chlorobromo-mixed species, were thoroughly studied and it was revealed for the first time the four groups of PHCZs shifted from chlorinated to being more brominated with increasing bromide level. The speciation of the four groups of PHCZs was modeled. It was revealed that the shift of PHCZs from chlorinated to being more brominated was caused by the reactivity differences between HOCl and HOBr in reactions forming PHCZs. Furthermore, this study revealed that the species numbers and concentrations of PHCZs formed in chlorination were much higher than those in chloramination, and the formation of PHCZs was decreased by ~50% with an increase of pH from 6.0 to 9.0. This study of the variety of PHCZs in chlorinated water is an important step toward revealing the occurrence of PHCZs in aquatic environments.3,6-Dibromo-9H-carbazole(cas: 6825-20-3Reference of 3,6-Dibromo-9H-carbazole) was used in this study.

3,6-Dibromo-9H-carbazole(cas: 6825-20-3) is used as a pharmaceutical intermediate, and also an important intermediate of synthesizing optoelectronic materials. It has been used in the preparation of N-(2-hydroxyethyl)-3,6-dibromocarbazole.Reference of 3,6-Dibromo-9H-carbazole

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Yang, Yisi; Li, Libo; Lin, Rui-Biao; Ye, Yingxiang; Yao, Zizhu; Yang, Ling; Xiang, Fahui; Chen, Shimin; Zhang, Zhangjing; Xiang, Shengchang; Chen, Banglin published an article in 2021. The article was titled 《Ethylene/ethane separation in a stable hydrogen-bonded organic framework through a gating mechanism》, and you may find the article in Nature Chemistry.Electric Literature of C12H7Br2N The information in the text is summarized as follows:

Porous materials are very promising for the development of cost- and energy-efficient separation processes, such as for the purification of ethylene from ethylene/ethane mixture-an important but currently challenging industrial process. Here we report a microporous hydrogen-bonded organic framework that takes up ethylene with very good selectivity over ethane through a gating mechanism. The material consists of tetracyano-bicarbazole building blocks held together through intermol. CN···H-C hydrogen bonding interactions, and forms as a threefold-interpenetrated framework with pores of suitable size for the selective capture of ethylene. The hydrogen-bonded organic framework exhibits a gating mechanism in which the threshold pressure required for guest uptake varies with the temperature Ethylene/ethane separation is validated by breakthrough experiments with high purity of ethylene (99.1%) at 333 K. Hydrogen-bonded organic frameworks are usually not robust, yet this material was stable under harsh conditions, including exposure to strong acidity, basicity and a variety of highly polar solvents. In addition to this study using 3,6-Dibromo-9H-carbazole, there are many other studies that have used 3,6-Dibromo-9H-carbazole(cas: 6825-20-3Electric Literature of C12H7Br2N) was used in this study.

3,6-Dibromo-9H-carbazole(cas: 6825-20-3) is used as a pharmaceutical intermediate, and also an important intermediate of synthesizing optoelectronic materials. It has been used as a reagent in the synthesis of P7C3-A20 which is a potent neuroprotective agent.Electric Literature of C12H7Br2N

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary