Category: 6630-33-7

Product Details of 6630-33-7In 2021 ,《Synthesis of new Schiff bases; Investigation of their in situ catalytic activity for Suzuki C-C coupling reactions and antioxidant activities》 was published in Journal of the Chinese Chemical Society (Weinheim, Germany). The article was written by Yilmaz, Oezguer. The article contains the following contents:

New series of Schiff bases I [R = H, 2-Br, 2,4-di-HOC6H3, etc.] had been synthesized from the reaction between cyclohepta-2,4,6-trien-1-ylmethanamine and different aldehydes, and characterized via using 1H NMR, 13C NMR, FTIR spectroscopy and GC-MS. After the successful synthesis, the in situ catalytic activity of all Schiff bases had been examined for Suzuki C-C cross-coupling reactions using phenylboronic acid, aryl bromides and PdCl2 as a catalyst. Before starting these investigations, reaction conditions were optimized using different bases and solvents. At the end of these reactions, the best efficiency was obtained in Et3N and EtOH. In addition to catalytic investigations, antioxidant activities of all synthesized Schiff bases were examined using DPPH and iron (Fe2+) chelation methods, and IC50 values were calculated While many mols. showed various amounts of antioxidant activity, especially mols. I [R = 2,4-di-HOC6H3, 4-(E)-styryl] showed the best activity compared to butylated hydroxytoluene (BHT) and butylated hydroxyanisole (BHA), which were used as pos. controls, in DPPH and iron chelating methods, resp. In addition to this study using o-Bromobenzaldehyde, there are many other studies that have used o-Bromobenzaldehyde(cas: 6630-33-7Product Details of 6630-33-7) was used in this study.

o-Bromobenzaldehyde(cas: 6630-33-7) is used in L-threonine aldolase-catalyzed enantio/diastereoselective aldol reactions.Product Details of 6630-33-7It is also used in L-threonine aldolase-catalyzed enantio and diastereoselective aldol reactions. Further, it reacts with trichloromethane to prepare 1-(2-bromo-phenyl)-2,2,2-trichloro-ethanol.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2019,Acta Crystallographica, Section E: Crystallographic Communications included an article by Anitha, Azhagan Ganapathi; Arunagiri, Chidambaram; Subashini, Annamalai. Category: bromides-buliding-blocks. The article was titled 《Synthesis, X-ray crystal structure, Hirshfeld surface analysis and DFT studies of (E)-N’-(2-bromobenzylidene)-4-methylbenzohydrazide》. The information in the text is summarized as follows:

The title mol., C15H13BrN2O, displays a trans configuration with respect to the C=N double bond. The dihedral angle between the bromo- and methyl-substituted benzene rings is 16.1 (3)°. In the crystal, mols. are connected by N-H·-O and weak C-H-O hydrogen bonds, forming R21(6) ring motifs and generating chains along the a-axis direction. The optimized structure generated theor. via d. functional theory (DFT) using standard B3LYP functional and 6-311 G(d,p) basis-set calculations renders good support to the exptl. data. The HOMO-LUMO behavior was elucidated to determine the energy gap. The intermol. interactions were quantified and analyzed using Hirshfeld surface anal. In the experimental materials used by the author, we found o-Bromobenzaldehyde(cas: 6630-33-7Category: bromides-buliding-blocks)

o-Bromobenzaldehyde(cas: 6630-33-7) is used in L-threonine aldolase-catalyzed enantio/diastereoselective aldol reactions.Category: bromides-buliding-blocksSynthetic applications of o-Bromobenzaldehyde include: synthesis of aza-fused polycyclic quinolines through copper-catalyzed cascade reaction, preparation of 1-substituted indazoles by CuI-catalyzed coupling with N-aryl hydrazides.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary