Category: 651341-68-3

Kolluru, Srinivas published the artcileNickel-Catalyzed Annulations of ortho-Haloarylimines, Safety of Ethyl 2-bromo-4-fluorobenzoate, the main research area is nickel catalyzed annulation ortho haloarylimine anti selectivity; amines; catalysis; chemometrics; kinetics; mechanism; nickel; reaction parametrization; spectroscopy; spirocycles.

We report the discovery, development, and mechanism of a nickel-catalyzed annulation reaction between o-haloarylimines and electron-poor olefins. The reaction produces two adjacent anti stereocenters and a free secondary amine. Spirocycles are formed from cyclic imines. We characterized the key oxidative addition intermediate and identified a major path leading to competing homocoupling products. The activation energy of oxidative addition and the rate of oxidative addition complex isomerization were determined The sensitivity of the reaction to reaction conditions was established in a quant. manner and both the scope and limitations of the method are presented.

ACS Catalysis published new progress about Activation energy. 651341-68-3 belongs to class bromides-buliding-blocks, name is Ethyl 2-bromo-4-fluorobenzoate, and the molecular formula is C9H8BrFO2, Safety of Ethyl 2-bromo-4-fluorobenzoate.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Zheng, Meifang published the artcileOxypalladation Initiating the Oxidative Heck Reaction with Alkenyl Alcohols: Synthesis of Isocoumarin-Alkanones, Quality Control of 651341-68-3, the main research area is isocoumarin alkanone preparation palladium catalyst oxidative Heck alkenyl alc.

Highly regioselective nucleopalladation for the oxidative coupling of internal alkynes with alkenyl alcs. by using green and low-costing oxygen as the sole oxidant was studied. This one-pot cascade cyclization proceeds through Pd-catalyzed intramol. C-O bond cyclization, insertion of nonbiased alkenyl alcs., -H elimination, and reinsertion of a HPdX species, which is finally transferred to the target ketones. This method has the advantages of mild conditions, good functional group tolerance, and can be performed with unactivated alkenes to afford isocoumarin derivatives

European Journal of Organic Chemistry published new progress about Alkenyl alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 651341-68-3 belongs to class bromides-buliding-blocks, name is Ethyl 2-bromo-4-fluorobenzoate, and the molecular formula is C9H8BrFO2, Quality Control of 651341-68-3.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Zhang, Qing-Yang published the artcileOne pot synthesis of dibenzodiazepinones via CuI catalysis in ethylene glycol, Recommanded Product: Ethyl 2-bromo-4-fluorobenzoate, the main research area is halobenzoate phenylenediamine cyclization copper catalyst ethylene glycol; dibenzodiazepinone preparation.

A one-pot protocol for the synthesis of dibenzodiazepinones was developed. Substituted Et 2-halobenzoates are cross-coupled with 1,2-phenylenediamine utilizing a ligand-free, CuI-catalyzed system, which spontaneously undergo intramol. N-acylation in ethylene glycol to give the corresponding products in high yields. This synthetic protocol provides a concise and efficient access to a wide variety of dibenzodiazepinones, including biol. active mols.

Chinese Chemical Letters published new progress about Aryl bromides Role: RCT (Reactant), RACT (Reactant or Reagent). 651341-68-3 belongs to class bromides-buliding-blocks, name is Ethyl 2-bromo-4-fluorobenzoate, and the molecular formula is C9H8BrFO2, Recommanded Product: Ethyl 2-bromo-4-fluorobenzoate.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary