Category: 62871-09-4

In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 62871-09-4 as follows. Formula: C10H19Br

To a stirred solution of (S)-nicotine (0.52 g, 3.2 mmol) in AcOH (10 ml) was added 10-bromo-dec-1-ene (1.66 g, 7.58 mmol).The mixture was heated at reflux for 3 days. AcOH was evaporated and the residue was dissolved in CHCl3.The mixture was washed with saturated aqueous NaHCO3, water and brine successively and dried.Evaporation of the solvent followed by titration with ether afforded 0.74 g (61%) of (S)-1-dec-9-enyl-3-(1-methyl-pyrrolidin-2-yl)-pyridinium bromide (NDNB-9e) as a brown oil. 1H NMR (300 MHz, CDCl3) delta 9.65 (1H, d, J=5.1 Hz), 9.14 (1H, s), 8.41(1H, d, J=8.1 Hz), 8.09 (1H, dd, J=8.1, 5.1 Hz), 5.75 (1H, m), 4.88-5.10 (4H, m), 3.54 (1H, t, J=8.1 Hz), 3.23 (1H, m), 2.45 (2H, m), 2.22 (3H, s), 1.70-2.10 (6H, m), 1.61 (1H, m), 1.10-1.40 (10H, m); 13C NMR (75 MHz, CDCl3) delta 146.46, 144.39, 143.74, 142.97, 139.07, 128.50, 114.33, 67.17, 62.25, 56.92, 40.74, 36.11, 33.93, 32.35, 29.42, 29.24, 29.15, 29.03, 26.35, 23.41.

According to the analysis of related databases, 62871-09-4, the application of this compound in the production field has become more and more popular.

Reference:
Patent; Crooks, Peter A.; Dwoshin, Linda; Xu, Rui; Ayers, Joshua T.; US2003/225142; (2003); A1;,
Bromide – Wikipedia,
bromide – Wiktionary

These common heterocyclic compound, 62871-09-4, name is 10-Bromodec-1-ene, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. 62871-09-4

Production of the carbodithioic acid ester Production Example 4 In a solution of 6 g of potassium hydroxide in 50 ml of methanol was dissolved 20 g of 10-undecenedithioic acid, an intermediate compound in Production Example 2, and 22 g of 10-bromo-1-decene was added dropwise with cooling on an ice bath. The mixture was stirred for 6 hours. The insoluble matter was filtered off and the solvent was then distilled off to recover 9-decenyl 10-undecenedithioate.

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 62871-09-4.

Reference:
Patent; KURARAY CO., LTD.; EP348166; (1994); B1;,
Bromide – Wikipedia,
bromide – Wiktionary