Reference of 615-87-2, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 615-87-2, name is 1,5-Dibromo-2,4-dimethylbenzene, This compound has unique chemical properties. The synthetic route is as follows.
Into an eggplant type flask having a capacity of 200 milliliter, dbb in an amount of 5.11 mmol (1.35 g), (2-pyridyl)trimethyl tin in an amount of 15.3 mmol (3.71 g), Pd (PPh3)2Cl2 in an amount of 0.408 mmol (0.286 g), lithium chloride in an amount of 51.1 mmol (2.17 g) and toluene as a solvent in an amount of 20 milliliter were placed and the resultant solution was refluxed for 3 days. After the resultant solution was cooled by leaving it standing, saturated potassium fluoride aqueous solution was added and the resultant solution was stirred for 30 minutes. After filtering the resultant solution, dichloromethane and 5 % sodium hydrogen carbonate aqueous solution were added to the filtrate and the resultant solution was extracted. Adding sodium sulfate into an organic layer and dehydrating the resultant mixture, the organic layer was removed through pressure reduction, and the remained substance was refined by means of silica gel column chromatography (hexane : ether= 4:1). After re-crystallizing the resultant substance with the use of heated hexane, white crystals of dpyx in an amount of 0.31 g was obtained (yield: 33 %). m.p.: 89 to 90 C
The chemical industry reduces the impact on the environment during synthesis 1,5-Dibromo-2,4-dimethylbenzene. I believe this compound will play a more active role in future production and life.
Reference:
Patent; IDEMITSU KOSAN CO., LTD.; Chuo University; EP1816134; (2007); A1;,
Bromide – Wikipedia,
bromide – Wiktionary