Category: 586-76-5

Yang, Qi-Liang; Jia, Hong-Wei; Liu, Ying; Xing, Yi-Kang; Ma, Rui-Cong; Wang, Man-Man; Qu, Gui-Rong; Mei, Tian-Sheng; Guo, Hai-Ming published their research in Organic Letters in 2021. The article was titled 《Electrooxidative Iridium-Catalyzed Regioselective Annulation of Benzoic Acids with Internal Alkynes》.HPLC of Formula: 586-76-5 The article contains the following contents:

Electrochem. driven, Cp*Ir(III)-catalyzed regioselective annulative couplings of benzoic acids with alkynes were established herein. The combination of Ir catalyst and electricity not only circumvents the need for stoichiometric amount of chem. oxidant, but also ensures broad reaction compatibility with a wide array of sterically and electronically diverse substrates. This electrochem. approach represents a sustainable strategy as an ideal alternative and supplement to the oxidative annulations methodol. to be engaged in the synthesis of isocoumarin derivatives The experimental process involved the reaction of 4-Bromobenzoic acid(cas: 586-76-5HPLC of Formula: 586-76-5)

4-Bromobenzoic acid(cas: 586-76-5) has been used to study the metabolic fate of 2-,3-and 4-bromo benzoic acids in rat hepatocytes incubation using high temperature liquid chromatography.HPLC of Formula: 586-76-5 It was used in bromine-specific detection of the metabolites of 2-,3-and 4-bromobenzoic acid in the urine and bile of rats by inductively coupled plasma mass spectrometry.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2022,Horvat, Monika; Iskra, Jernej published an article in Green Chemistry. The title of the article was 《Oxidative cleavage of C-C double bond in cinnamic acids with hydrogen peroxide catalysed by vanadium(V) oxide》.Application of 586-76-5 The author mentioned the following in the article:

A cheap, green, mild and environmentally friendly method for the selective cleavage of carbon-carbon double bonds with a 30% aqueous solution of hydrogen peroxide as the oxidant and vanadium(V) oxide as the catalyst have been developed. The selectivity of the oxidative cleavage of cinnamic acid derivatives RCH=CHC(O)OR1 (R = 4-hydroxyphenyl, 2,4-dichlorophenyl, 4-hydroxy-3-methoxyphenyl, etc.; R1 = H, Et) depends on the substituents and the solvent used (DME – MeOCH2CH2OMe, TFE – 2,2,2-trifluoroethanol or MeCN). In DME, p-hydroxy derivatives were selectively converted to benzaldehyde derivatives RCHO, and in TFE, oxidative cleavage led to the formation of benzoquinone derivatives I (R2 = H, OMe), while in MeCN, cinnamic acid derivatives were selectively converted to benzoic acid derivatives RC(O)OH. Ferulic acid was quant. and selectively converted to vanillin in a 91% isolated yield on a gram scale. 3,6-Bis(4-hydroxy-3-methoxyphenyl)tetrahydro-1H,4H-furo[3,4-c]furan-1,4-dione was isolated as an intermediate, which was confirmed by in situ ATR-IR spectroscopy, while the formation of diols or epoxides was not observed The analogus styrene derivative, 4-vinylguaiacol 1e was also selectively converted to either vanillin or 2-methoxyquinone in a high yield. The green metric for the conversion of ferulic acid to vanillin by different methods was calculated and compared to this method, and showed the method has better environmental parameters.4-Bromobenzoic acid(cas: 586-76-5Application of 586-76-5) was used in this study.

4-Bromobenzoic acid(cas: 586-76-5) has been used in bromine-specific detection of the metabolites of 2-,3-and 4-bromobenzoic acid in the urine and bile of rats by inductively coupled plasma mass spectrometry.Application of 586-76-5 It was used to study the metabolic fate of 2-,3-and 4-bromo benzoic acids in rat hepatocytes incubation using high temperature liquid chromatography.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2019,Dalton Transactions included an article by Gong, Dawei; Hu, Bowen; Chen, Dafa. COA of Formula: C7H5BrO2. The article was titled 《Bidentate Ru(II)-NC complexes as catalysts for the dehydrogenative reaction from primary alcohols to carboxylic acids》. The information in the text is summarized as follows:

Four Ru(II)-NC complexes were synthesized by one-step processes from the corresponding NC ligands with RuHCl(CO)(PPh3)3. These complexes were tested as catalysts for alc. dehydrogenative reactions, and complex {(C5H4N)-(C6H4)}RuCl(CO)(PPh3)2 (1) showed the highest activity. With KOH as the nucleophile and 0.5 mol% catalyst loading, a series of carboxylic acids were synthesized in toluene without any oxidant. Catalyst 1 could be transformed to complex {(C5H4N)-(C6H4)}RuH(CO)(PPh3)2 (6) when treated with KOH and benzyl alc. Complex 6 further reacted with PhCHO and H2O to generate product {(C5H4N)-(C6H4)}Ru(OCOPh)(CO)(PPh3)2 (7). Complexes 6 and 7 exhibited similar efficiency to complex 1, suggesting that they can be regarded as the catalytic intermediates of. The experimental part of the paper was very detailed, including the reaction process of 4-Bromobenzoic acid(cas: 586-76-5COA of Formula: C7H5BrO2)

4-Bromobenzoic acid(cas: 586-76-5) has been used in bromine-specific detection of the metabolites of 2-,3-and 4-bromobenzoic acid in the urine and bile of rats by inductively coupled plasma mass spectrometry.COA of Formula: C7H5BrO2 It was used to study the metabolic fate of 2-,3-and 4-bromo benzoic acids in rat hepatocytes incubation using high temperature liquid chromatography.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Rapid synthesis of acyl fluorides from carboxylic acids with Cu(O2CCF2SO2F)2》 was published in Tetrahedron Letters in 2020. These research results belong to Le, Bingjun; Wu, Hao; Hu, Xiaojun; Zhou, Xiumiao; Guo, Yong; Chen, Qing-Yun; Liu, Chao. Recommanded Product: 4-Bromobenzoic acid The article mentions the following:

A rapid, simple and efficient acyl fluoride RC(O)F [R = Ph, Bn, 2-thienyl, etc.] synthesis from carboxylic acids with Cu(O2CCF2SO2F)2 as a deoxofluorination reagent was developed. Notably, Cu(O2CCF2SO2F)2 was readily prepared in large scale from inexpensive starting material and previously used as a good trifluoromethylating reagent. The results came from multiple reactions, including the reaction of 4-Bromobenzoic acid(cas: 586-76-5Recommanded Product: 4-Bromobenzoic acid)

4-Bromobenzoic acid(cas: 586-76-5) has been used in bromine-specific detection of the metabolites of 2-,3-and 4-bromobenzoic acid in the urine and bile of rats by inductively coupled plasma mass spectrometry.Recommanded Product: 4-Bromobenzoic acid It was used to study the metabolic fate of 2-,3-and 4-bromo benzoic acids in rat hepatocytes incubation using high temperature liquid chromatography.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Recommanded Product: 4-Bromobenzoic acidIn 2020 ,《A practical catalytic reductive amination of carboxylic acids》 was published in Chemical Science. The article was written by Stoll, Emma L.; Tongue, Thomas; Andrews, Keith G.; Valette, Damien; Hirst, David J.; Denton, Ross M.. The article contains the following contents:

Reductive alkylation reactions of amines using carboxylic acids as nominal electrophiles was reported. The two-step reaction exploits the dual reactivity of phenylsilane and involves a silane-mediated amidation followed by a Zn(OAc)2-catalyzed amide reduction The reaction is applicable to a wide range of amines and carboxylic acids and has been demonstrated on a large scale (305 mmol of amine). The rate differential between the reduction of tertiary and secondary amide intermediates is exemplified in a convergent synthesis of the antiretroviral medicine maraviroc. Mechanistic studies demonstrate that a residual 0.5 equiv of carboxylic acid from the amidation step is responsible for the generation of silane reductants with augmented reactivity, which allow secondary amides, previously unreactive in zinc/phenylsilane systems, to be reduced. In the part of experimental materials, we found many familiar compounds, such as 4-Bromobenzoic acid(cas: 586-76-5Recommanded Product: 4-Bromobenzoic acid)

4-Bromobenzoic acid(cas: 586-76-5) has been used to study the metabolic fate of 2-,3-and 4-bromo benzoic acids in rat hepatocytes incubation using high temperature liquid chromatography. It was used in bromine-specific detection of the metabolites of 2-,3-and 4-bromobenzoic acid in the urine and bile of rats by inductively coupled plasma mass spectrometry.Recommanded Product: 4-Bromobenzoic acid

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

The author of 《Magnetic Lignosulfonate-Supported Pd Complex: Renewable Resource-Derived Catalyst for Aqueous Suzuki-Miyaura Reaction》 were Nasrollahzadeh, Mahmoud; Issaabadi, Zahra; Varma, Rajender S.. And the article was published in ACS Omega in 2019. Electric Literature of C7H5BrO2 The author mentioned the following in the article:

A novel strategy is described to prepare magnetic Pd nanocatalyst by conjugating lignin with Fe3O4 nanoparticles via activation of calcium lignosulfonate, followed by combination with Fe3O4 nanoparticles. Tethering 5-amino-1H-tetrazole to calcium lignosulfonate-magnetite hybrid through 3-chloropropyl triethoxysilane enabled coordination of Pd salt with Fe3O4-lignosulfonate@5-amino-1H-tetrazole. The underlying changes of the lignosulfonate are identified, and the structural morphol. of attained Fe3O4-lignosulfonate@5-amino-1H-tetrazole-Pd(II) (FLA-Pd) is characterized by Fourier transform IR, thermogravimetry DTA, energy-dispersive spectrometry, field-emission SEM, transmission electron microscopy, and vibrating sample magnetometer (VSM). The synthesized FLA-Pd displayed high activity for phosphine-free C(sp2)-C(sp2) coupling in water, and the catalyst could be reused for seven successive cycles.4-Bromobenzoic acid(cas: 586-76-5Electric Literature of C7H5BrO2) was used in this study.

4-Bromobenzoic acid(cas: 586-76-5) has been used to study the metabolic fate of 2-,3-and 4-bromo benzoic acids in rat hepatocytes incubation using high temperature liquid chromatography. It was used in bromine-specific detection of the metabolites of 2-,3-and 4-bromobenzoic acid in the urine and bile of rats by inductively coupled plasma mass spectrometry.Electric Literature of C7H5BrO2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Copper and L-(-)-quebrachitol catalyzed hydroxylation and amination of aryl halides under air》 was written by Liang, Xinjie; Li, Hui; Du, Fangyu; Zhang, Yongsheng; Dong, Jinhua; Bao, Xuefei; Wu, Ying; Chen, Guoliang. Formula: C7H5BrO2 And the article was included in Tetrahedron Letters in 2020. The article conveys some information:

L-(-)-Quebrachitol, a natural product obtained from waste water of the rubber industry, was utilized as an efficient ligand for the copper-catalyzed hydroxylation and amination of aryl halides to selectively give phenols and aryl amines in water or 95% ethanol. In addition, the hydroxylation of 2-chloro-4-hydroxybenzoic acid was validated on a 100-g scale under air. In the experimental materials used by the author, we found 4-Bromobenzoic acid(cas: 586-76-5Formula: C7H5BrO2)

4-Bromobenzoic acid(cas: 586-76-5) has been used to study the metabolic fate of 2-,3-and 4-bromo benzoic acids in rat hepatocytes incubation using high temperature liquid chromatography.Formula: C7H5BrO2 It was used in bromine-specific detection of the metabolites of 2-,3-and 4-bromobenzoic acid in the urine and bile of rats by inductively coupled plasma mass spectrometry.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2022,Li, Xing-Ren; Hu, Kun; Yan, Bing-Chao; Li, Xiao-Nian; Sun, Han-Dong; Liu, Yang; Puno, Pema-Tenzin published an article in Bioorganic Chemistry. The title of the article was 《Scopariusicides D-M, ent-clerodane-based isomeric meroditerpenoids with a cyclobutane-fused γ/δ-lactone core from Isodon scoparius》.Formula: C7H5BrO2 The author mentioned the following in the article:

Scopariusicides D-M (1-10), ten new ent-clerodane-based meroditerpenoids with a cyclobutane-fused γ/δ-lactone core, were isolated from Isodon scoparius. Their structures were determined by comprehensive anal. of spectroscopic data, single-crystal X-ray diffraction, chem. transformation, and TDDFT ECD calculation A plausible biosynthetic pathway of 1-10 was proposed in which the asym. cyclobutane ring was formed via a crossed “”head-to-tail”” intermol. [2 + 2] cycloaddition in anti/syn facial approaches between an ent-clerodane lactone and a cis-4-hydroxycinnamic acid. Bioactivity evaluation manifested that 5 exhibited significant neuroprotective effect against corticosterone-induced injury in PC12 cells, while 6 and 7 exhibited moderate immunosuppressive activity against human T cell proliferation stimulated by anti-CD3/anti-CD28 mAb. The experimental process involved the reaction of 4-Bromobenzoic acid(cas: 586-76-5Formula: C7H5BrO2)

4-Bromobenzoic acid(cas: 586-76-5) has been used to study the metabolic fate of 2-,3-and 4-bromo benzoic acids in rat hepatocytes incubation using high temperature liquid chromatography.Formula: C7H5BrO2 It was used in bromine-specific detection of the metabolites of 2-,3-and 4-bromobenzoic acid in the urine and bile of rats by inductively coupled plasma mass spectrometry.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Product Details of 586-76-5In 2020 ,《A recyclable, metal-free mechanochemical approach for the oxidation of alcohols to carboxylic acids》 appeared in Molecules. The author of the article were Denlinger, Kendra Leahy; Carr, Preston; Waddell, Daniel C.; Mack, James. The article conveys some information:

The oxidation of primary alcs. under mechanochem. conditions in a Spex8000M Mixer/Mill was investigated. To facilitate ease of separation and recyclability, a polystyrene-bound version of a TEMPO catalyst was employed. When paired with Oxone in a stainless-steel vial with a stainless-steel ball, several primary alcs. were successfully oxidized to the corresponding carboxylic acids. The product was isolated using gravity filtration, which also allowed for the polystyrene-bound TEMPO catalyst to be recovered and reused in subsequent oxidation reactions. Furthermore, it was demonstrated that the size and steric hindrance of the primary alc. does not hinder the rate of the reaction. Finally, the aldehyde was selectively obtained from a primary alc. under ball milling conditions by using a combination of non-supported TEMPO with a copper vial and copper ball. In the part of experimental materials, we found many familiar compounds, such as 4-Bromobenzoic acid(cas: 586-76-5Product Details of 586-76-5)

4-Bromobenzoic acid(cas: 586-76-5) has been used to study the metabolic fate of 2-,3-and 4-bromo benzoic acids in rat hepatocytes incubation using high temperature liquid chromatography. It was used in bromine-specific detection of the metabolites of 2-,3-and 4-bromobenzoic acid in the urine and bile of rats by inductively coupled plasma mass spectrometry.Product Details of 586-76-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2019,Organic Letters included an article by Munoz, Socrates B.; Dang, Huong; Ispizua-Rodriguez, Xanath; Mathew, Thomas; Prakash, G. K. Surya. Formula: C7H5BrO2. The article was titled 《Direct Access to Acyl Fluorides from Carboxylic Acids Using a Phosphine/Fluoride Deoxyfluorination Reagent System》. The information in the text is summarized as follows:

A fast and simple method for deoxyfluorination of carboxylic acids is presented. The protocol employs commodity chems. (PPh3, NBS, fluoride), affording products in excellent yields under mild conditions. Acyloxyphosphonium ion, the key reaction intermediate, was identified by NMR spectroscopic methods. Bronsted acidic conditions are essential for efficient C-F bond formation. The protocol displays scalability, high functional group tolerance, chemoselectivity, and easy purification of products. Deoxyfluorination of active pharmaceutical ingredients was established. In the experimental materials used by the author, we found 4-Bromobenzoic acid(cas: 586-76-5Formula: C7H5BrO2)

4-Bromobenzoic acid(cas: 586-76-5) has been used in bromine-specific detection of the metabolites of 2-,3-and 4-bromobenzoic acid in the urine and bile of rats by inductively coupled plasma mass spectrometry.Formula: C7H5BrO2 It was used to study the metabolic fate of 2-,3-and 4-bromo benzoic acids in rat hepatocytes incubation using high temperature liquid chromatography.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary