Isomeric change in the phenol series. (Third notice.) was written by Ling, Arthur R.. And the article was included in Journal of the Chemical Society, Transactions in 1889.Recommanded Product: 4-Bromo-2-chloro-6-nitrophenol This article mentions the following:
An interesting and at a first sight rather complicated case of isomeric change takes place, when orthochloroparabromophenol is nitrated by warming it in an acetic acid solution with a slight excess of nitric acid, namely, together with the normal products, ortho-chloroparabromorthonitrophenol and orthochlororthoparadinitrophenol, which are formed in the largest quantity, a not inconsiderable amount of diorthochlorobromoparanitrophenol is also produced. The production of orthochlororthoparadinitrophenol, and the consequent elimination of bromine renders this case, however, equivalent to the action of bromine renders this case, however, equivalent to the action of bromine on orthochloroparabromoorthonitrophenol, the latter being without doubt the initial product of the reaction. The isomeric change of parachlororthobromorthonitrophenol into orthochloroparabromoorthonitrophenol does not take place at all, and that a mistake which must have arisen in working with impure materials is explained. In the experiment, the researchers used many compounds, for example, 4-Bromo-2-chloro-6-nitrophenol (cas: 58349-01-2Recommanded Product: 4-Bromo-2-chloro-6-nitrophenol).
4-Bromo-2-chloro-6-nitrophenol (cas: 58349-01-2) belongs to organobromine compounds. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.Recommanded Product: 4-Bromo-2-chloro-6-nitrophenol
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary