5437-45-6 Archives - Bromides-buliding-blocks

Huang, Cheng’s team published research in Chem in 2021 | CAS: 5437-45-6

Benzyl 2-bromoacetate(cas: 5437-45-6) belongs to benzyl acetate. Benzyl acetate is a synthetic chemical produced for industry from benzyl alcohol and acetic acid, but is also naturally present in the essential oils of many plants, including jasmine and ylang ylang.Name: Benzyl 2-bromoacetate

Huang, Cheng; Qiao, Jia; Ci, Rui-Nan; Wang, Xu-Zhe; Wang, Yang; Wang, Jing-Hao; Chen, Bin; Tung, Chen-Ho; Wu, Li-Zhu published their research in Chem in 2021. The article was titled 《Quantum dots enable direct alkylation and arylation of allylic C(sp3)-H bonds with hydrogen evolution by solar energy》.Name: Benzyl 2-bromoacetate The article contains the following contents:

A general and mild strategy using semiconductor quantum dots (QDs) as photocatalysts for coupling a broad range of available allylic C(sp3)-H bonds with α-amino C-H bonds or heteroarenes, resp., under sunlight irradiation (> 85 examples) was reported. The protocol bypasses stoichiometric oxidant or reductant and pre-functionalization of both the coupling partners and produces hydrogen (H2) as the byproduct. The outstanding efficiency and selectivity and step- and atom-economy represents the first direct alkylation and arylation of allylic C(sp3)-H bonds with hydrogen evolution powered by solar energy. The experimental process involved the reaction of Benzyl 2-bromoacetate(cas: 5437-45-6Name: Benzyl 2-bromoacetate)

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Li, Fusheng’s team published research in Synthesis in 2021 | CAS: 5437-45-6

Li, Fusheng; Lin, Shuangjie; Li, Xiyu; Shi, Lei published their research in Synthesis in 2021. The article was titled 《Photocatalytic Generation of π-Allyltitanium Complexes from Butadiene via a Radical Strategy》.SDS of cas: 5437-45-6 The article contains the following contents:

This study reported a conceptually new radical strategy for the photocatalytic generation of π-allyltitanium complexes from butadiene. This novel and environmentally benign strategy enables the direct three-component allylation of carbonyls with 1,3-butadiene and α-bromocarboxylates, providing rapid access to valuable homoallylic alcs. with exceptional regio- and diastereoselectivity control. The experimental process involved the reaction of Benzyl 2-bromoacetate(cas: 5437-45-6SDS of cas: 5437-45-6)

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Li, Sha’s team published research in Organic Letters in 2019 | CAS: 5437-45-6

Benzyl 2-bromoacetate(cas: 5437-45-6) belongs to benzyl acetate. Benzyl acetate is an aromatic chemical, usually appearing as a clear liquid with a moderate sweet-jasmine fragrance. This compound appears as a component of some of our fragrance blends.Related Products of 5437-45-6

The author of 《NHC-Catalyzed Aldol-Like Reactions of Allenoates with Isatins: Regiospecific Syntheses of γ-Functionalized Allenoates》 were Li, Sha; Tang, Ziwei; Wang, Yang; Wang, Dan; Wang, Zhanlin; Yu, Chenxia; Li, Tuanjie; Wei, Donghui; Yao, Changsheng. And the article was published in Organic Letters in 2019. Related Products of 5437-45-6 The author mentioned the following in the article:

An N-heterocyclic carbene (NHC) catalyzed γ-specific aldol-like reaction between allenoates and isatins has been achieved under mild conditions, giving trisubstituted allene derivatives bearing isatin moiety in moderate to good yields with high diastereoselectivity and excellent atom efficiency. The DFT computations indicated that the formation of the γ-adduct was more energetically favorable than that of the α-adduct. The result reported herein opens a new route for NHC-promoted allenoate-involved reaction. In addition to this study using Benzyl 2-bromoacetate, there are many other studies that have used Benzyl 2-bromoacetate(cas: 5437-45-6Related Products of 5437-45-6) was used in this study.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Travagin, Fabio’s team published research in Synlett in 2020 | CAS: 5437-45-6

《Synthesis of Two Novel Mixed Bifunctional Chelating Agents: DO2AP(tBu)4 and DO3AP(tBu)4》 was written by Travagin, Fabio; Biondi, Luca; Lattuada, Luciano; Giovenzana, Giovanni B.. Recommanded Product: 5437-45-6 And the article was included in Synlett in 2020. The article conveys some information:

A convenient synthesis of two novel macrocyclic bifunctional chelating agents (BFCAs) I (R = H, carboxymethyl), formally derived from the well-known ligands DO3A and DOTA by selective replacement of one carboxymethyl side arm with a phosphonomethyl residue, is reported. The results came from multiple reactions, including the reaction of Benzyl 2-bromoacetate(cas: 5437-45-6Recommanded Product: 5437-45-6)

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Shyam, Radhe’s team published research in Biopolymers in 2019 | CAS: 5437-45-6

Benzyl 2-bromoacetate(cas: 5437-45-6) has been used in the alkylation of (-)-2,3-O-isopropylidene-D-threitol that afforded lipopeptide, 2-[(4R,5R)-5-({[(9H-fluoren-9-yl)methoxy]carbonylaminomethyl}-2,2-dimethyl-1,3-dioxolan-4-yl)methoxy]acetic acid.Application of 5437-45-6

The author of 《NCα-gem-dimethylated peptoid side chains: A novel approach for structural control and peptide sequence mimetics》 were Shyam, Radhe; Nauton, Lionel; Angelici, Gaetano; Roy, Olivier; Taillefumier, Claude; Faure, Sophie. And the article was published in Biopolymers in 2019. Application of 5437-45-6 The author mentioned the following in the article:

The design of linear peptoid oligomers adopting well-defined secondary structures while mimicking defined peptide primary sequences is a major challenge in the context of drug discovery. To this end, chemists have developed cis-inducing peptoid side chains to build robust polyproline type I helixes. However, the number of efficient examples remains scarce and chem. diversity accessible through the use of these side chains is limited. Herein, we introduce an array of NCα-gem-dimethylated peptoid residues mimicking proteinogenic amino acids. Submonomer synthesis and block-coupling approaches were explored to access heterooligomers incorporating these novel types of side chains. NMR studies of monomer and trimer models showed that the NCα-gem-dimethylated groups exert complete cis control on the backbone amide conformation. Lastly, a preliminary mol. modeling study gave an insight into the preferred orientation of the substituents of the NCα-gem-dimethyl side chains relative to the peptoid backbone. After reading the article, we found that the author used Benzyl 2-bromoacetate(cas: 5437-45-6Application of 5437-45-6)

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Zeng, Rong’s team published research in Organic Letters in 2019 | CAS: 5437-45-6

In 2019,Organic Letters included an article by Zeng, Rong; Shan, Changyu; Liu, Ming; Jiang, Kun; Ye, Ying; Liu, Tian-Yu; Chen, Ying-Chun. Category: bromides-buliding-blocks. The article was titled 《[4 + 1 + 1] Annulations of α-Bromo Carbonyls and 1-Azadienes toward Fused Benzoazaheterocycles》. The information in the text is summarized as follows:

An unexpected [4 + 1 + 1] annulation between α-bromo carbonyls and 1-azadienes, derived from 2-methylenebenzofuran-3(2H)-ones or 2-methylenebenzo[b]thiophene-3(2H)-ones, was observed in the presence of DABCO and Cs2CO3. These reactions stand in contrast to the common [4 + 1] cyclization reactions of azadienes with the related sulfonium ylides. A range of fused benzofuro[3,2-b]pyridines and benzo[4,5]thieno[3,2-b]pyridines were efficiently constructed in fair to excellent yields. In the part of experimental materials, we found many familiar compounds, such as Benzyl 2-bromoacetate(cas: 5437-45-6Category: bromides-buliding-blocks)

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Ma, Shucheng’s team published research in ACS Catalysis in 2021 | CAS: 5437-45-6

Ma, Shucheng; Li, Fangjie; Zhang, Guisheng; Shi, Lei; Wang, Xiaoming published their research in ACS Catalysis in 2021. The article was titled 《Highly Regioselective Difluoroalkylarylation of Butadiene through a Nickel-Catalyzed Tandem Radical Process》.Product Details of 5437-45-6 The article contains the following contents:

A nickel-catalyzed reaction of butadiene with easily accessible difluoroalkyl bromides and arylboronic acids has been realized, affording the corresponding 1,4-difluoroalkylarylation products in good yields with high regioselectivities. The procedure can also be successfully extended to nonfluorinated alkyl bromides. Radical clock experiment suggests that a key alkyl radical is involved in the catalysis. The operational simplicity, excellent functional-group compatibility, and high efficiency would render this nickel-catalyzed three-component reaction highly promising for the cost-efficient synthesis of difluoroalkylated compounds In addition to this study using Benzyl 2-bromoacetate, there are many other studies that have used Benzyl 2-bromoacetate(cas: 5437-45-6Product Details of 5437-45-6) was used in this study.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Yamazaki, Ken’s team published research in ACS Catalysis in 2021 | CAS: 5437-45-6

Yamazaki, Ken; Gabriel, Pablo; Di Carmine, Graziano; Pedroni, Julia; Farizyan, Mirxan; Hamlin, Trevor A.; Dixon, Darren J. published an article in 2021. The article was titled 《General Pyrrolidine Synthesis via Iridium-Catalyzed Reductive Azomethine Ylide Generation from Tertiary Amides and Lactams》, and you may find the article in ACS Catalysis.Recommanded Product: 5437-45-6 The information in the text is summarized as follows:

An iridium-catalyzed reductive generation of both stabilized and unstabilized azomethine ylides and their application to functionalized pyrrolidines, e.g., I synthesis via [3+2] dipolar cycloaddition reactions was described. Proceeded under mild reaction conditions from both amide and lactam precursors, possessed a suitably positioned electron-withdrawing or a trimethylsilyl group, using catalytic Vaska’s complex [IrCl(CO)(PPh3)2] and tetramethyldisiloxane (TMDS) as a terminal reductant, a broad range of (un)stabilized azomethine ylides were accessible. Subsequent regio- and diastereoselective, inter- and intramol., and dipolar cycloaddition reactions with variously substituted electron-deficient alkenes enabled ready and efficient access to structurally complex pyrrolidine architectures. D. functional theory (DFT) calculations of the dipolar cycloaddition reactions uncovered an intimate balance between asynchronicity and interaction energies of transition structures, which ultimately control the unusual selectivities observed in certain cases. In the part of experimental materials, we found many familiar compounds, such as Benzyl 2-bromoacetate(cas: 5437-45-6Recommanded Product: 5437-45-6)

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Zhu, Keyong’s team published research in Organic Letters in 2022 | CAS: 5437-45-6

In 2022,Zhu, Keyong; Cao, Mengting; Zhao, Guanzhen; Zhao, Jingjing; Li, Pan published an article in Organic Letters. The title of the article was 《Visible Light-Promoted Diazoacetates and Nitriles Generating Nitrilium Ions Trapped by Benzotriazoles and Carboxylic Acids》.Computed Properties of C9H9BrO2 The author mentioned the following in the article:

A visible light-promoted generation of nitrilium ions from diazoacetates and nitriles was developed. The reaction utilized visible light transformation of diazoacetates to the free carbene that was trapped by nitriles to generate nitrilium ions, followed by nucleophilic attack on the benzotriazoles and carboxylic acids. This protocol provided an efficient and practical approach to N-imidoylbenzotriazoles and diacylglycine esters in good to excellent yields. In the experiment, the researchers used many compounds, for example, Benzyl 2-bromoacetate(cas: 5437-45-6Computed Properties of C9H9BrO2)

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Liang, Hui’s team published research in Chemical Science in 2022 | CAS: 5437-45-6

In 2022,Liang, Hui; Ji, Dong-Sheng; Xu, Guo-Qiang; Luo, Yong-Chun; Zheng, Haixue; Xu, Peng-Fei published an article in Chemical Science. The title of the article was 《Metal-free, visible-light induced enantioselective three-component dicarbofunctionalization and oxytrifluoromethylation of enamines via chiral phosphoric acid catalysis》.HPLC of Formula: 5437-45-6 The author mentioned the following in the article:

Using diverse carbon-centered radical precursors and electron-rich (hetero)aromatics and alcs. as nucleophiles, a visible-light driven chiral phosphoric acid (CPA) catalyzed asym. intermol., three-component radical-initiated dicarbofunctionalization and oxytrifluoromethylation of enamines was developed, which provides a straightforward access to chiral arylmethylamines, aza-hemiacetals and γ-amino acid derivatives with excellent enantioselectivity. As far as this is the first example of constructing a chiral C-O bond using simple alcs. via visible-light photocatalysis. Chiral phosphoric acid played multiple roles in the reaction, including controlling the reaction stereoselectivity and promoting the generation of radical intermediates by activating Togni’s reagent. Mechanistic studies also suggested the importance of the N-H bond of the enamine and indole for the reactions. In addition to this study using Benzyl 2-bromoacetate, there are many other studies that have used Benzyl 2-bromoacetate(cas: 5437-45-6HPLC of Formula: 5437-45-6) was used in this study.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary