Category: 5392-10-9

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 5392-10-9, formula is C9H9BrO3, Name is 2-Bromo-4,5-dimethoxybenzaldehyde. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Quality Control of 5392-10-9.

Zhu, Ling;Chen, Lei;Shao, Xusheng;Cheng, Jiagao;Yang, Qing;Qian, Xuhong research published 《 Novel inhibitors of an insect pest chitinase: Design and optimization of 9-O-aromatic and heterocyclic esters of berberine》, the research content is summarized as follows. OfChi-h, a lepidopteran-exclusive glycoside hydrolase family 18 (GH18) chitinase from the agricultural insect pest Ostrinia furnacalis, is a promising mol. target candidate for pest control and management. Berberine (BER), a traditional Chinese medicine, binds to a wide variety of glycosyl hydrolases via an identical mechanism, showing potential as a pesticide lead compound In this work, we found that BER was a moderate inhibitor of OfChi-h with a Ki of 16.1μM. To improve its efficacy, a series of BER derivatives featuring an ester bond linked to an aromatic or heterocyclic aromatic ring at the 9-position were designed and evaluated as effective OfChi-h inhibitors. The most potent compound, compound 19e with a nicotinate group, exhibited a Ki of 0.093μM. Mol. docking anal. suggested that the common binding mode of BER derivatives featured a network of π-π stacking and electrostatic interactions and that the group at the 9-position enhanced the van der Waals and hydrogen bonding interactions. Administration of the BER derivative 19c to 4th-instar O. furnacalis larvae in an artificial diet led to their impaired growth and metamorphosis. This work provides a new starting point for the modification of BER for use in pest control.

5392-10-9, 2-Bromo-4,5-dimethoxybenzaldehyde is a useful research compound. Its molecular formula is C9H9BrO3 and its molecular weight is 245.07 g/mol. The purity is usually 95%.
2-Bromo-4,5-dimethoxybenzaldehyde is a synthetic compound that has been shown to be an effective agent for inducing apoptosis in leukemia cells. It is an efficient method for synthesizing the compound and ha2-Bromo-4,5-dimethoxybenzaldehyde induces cell death by topoisomerase-mediated DNA cleavage, which results in chromosomal fragmentation and high levels of reactive oxygen species in the cell., Quality Control of 5392-10-9

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 5392-10-9, formula is C9H9BrO3, The most pervasive is the naturally produced bromomethane. Safety of 2-Bromo-4,5-dimethoxybenzaldehyde

Zhu, Yi-Ming;Fang, Yizhan;Li, Haiyan;Xu, Xiao-Ping;Ji, Shun-Jun research published 《 Divergent Reaction of Isocyanides with o-Bromobenzaldehydes: Synthesis of Ketenimines and Lactams with Isoindolinone Cores》, the research content is summarized as follows. A divergent reaction of isocyanides RNC (R = tert-Bu, cyclohexyl, adamantyl, etc.) with o-bromobenzaldehydes such as 2-bromo-4,5-dimethoxybenzaldehyde, 6-bromo-2H-1,3-benzodioxole-5-carbaldehyde, 2-bromopyridine-3-carbaldehyde for the synthesis of isoindolinone-derived ketenimines such as I and lactams such as II was disclosed. The reaction features readily available reactants, relatively mild conditions, and high yields of products. Ketenimines could be applied in further transformations for access to other functional mols. A mechanism study showed that the palladium-migration/imine-insertion process was the key step in this reaction.

5392-10-9, 2-Bromo-4,5-dimethoxybenzaldehyde is a useful research compound. Its molecular formula is C9H9BrO3 and its molecular weight is 245.07 g/mol. The purity is usually 95%.
2-Bromo-4,5-dimethoxybenzaldehyde is a synthetic compound that has been shown to be an effective agent for inducing apoptosis in leukemia cells. It is an efficient method for synthesizing the compound and ha2-Bromo-4,5-dimethoxybenzaldehyde induces cell death by topoisomerase-mediated DNA cleavage, which results in chromosomal fragmentation and high levels of reactive oxygen species in the cell., Safety of 2-Bromo-4,5-dimethoxybenzaldehyde

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 5392-10-9, formula is C9H9BrO3, Name is 2-Bromo-4,5-dimethoxybenzaldehyde. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Synthetic Route of 5392-10-9.

Zhong, Jiankai;Hu, Rui;Sang, Jingjing;Rao, Weidong research published 《 Gold(I)-catalyzed intramolecular [4 + 2] cycloaddition of ortho-(N-tethered 1,6-diynyl)benzaldehydes to 3,4-dihydrobenzo[f]isoquinolin-1(2H)-ones》, the research content is summarized as follows. An efficient synthetic method to prepare 3,4-dihydrobenzo[f]isoquinolin-1(2H)-ones such as I [R¹ = H, F, Ph, etc.; R² = H, Me, Cl, etc.; R³ = H, OMe, Ph; R⁴ = Ts, Bs; R⁵ = H, Me, octyl, etc.; R¹R² = OCH₂O] through gold(I)-catalyzed intramol. [4 + 2] benzannulation of ortho-(N-tethered 1,6-diynyl)benzaldehydes at a low catalyst loading of 2 mol% was described. The product of 3,4-dihydrobenzo[f]isoquinolin-1(2H)-ones I could be easily transformed to benzo[f]isoquinolin-1-ols by simply treating with phenylmagnesium bromide under mild conditions. The structures of compounds I [R¹ = H, R² = H, R³ = H, R⁴ = Ts, R⁵ = Me] and I [R¹ = H, R² = H, R³ = Ph, R⁴ = Ts, R⁵ = H] were also ascertained by X-ray crystallog. anal.

Synthetic Route of 5392-10-9, 2-Bromo-4,5-dimethoxybenzaldehyde is a useful research compound. Its molecular formula is C9H9BrO3 and its molecular weight is 245.07 g/mol. The purity is usually 95%.
2-Bromo-4,5-dimethoxybenzaldehyde is a synthetic compound that has been shown to be an effective agent for inducing apoptosis in leukemia cells. It is an efficient method for synthesizing the compound and ha2-Bromo-4,5-dimethoxybenzaldehyde induces cell death by topoisomerase-mediated DNA cleavage, which results in chromosomal fragmentation and high levels of reactive oxygen species in the cell., 5392-10-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 5392-10-9, formula is C9H9BrO3, The most pervasive is the naturally produced bromomethane. Application of C9H9BrO3

Zhang, Yan;Liu, Jian-Quan;Wang, Xiang-Shan research published 《 Copper(I)-catalyzed synthesis of isoindolo[1,2-b]quinazoline derivatives via an α-arylation under Pd and ligand free conditions》, the research content is summarized as follows. A tandem cyclization reaction of di-Et 2-(2-aminobenzamido)malonates 5-R-2-NH₂C₆H₃C(O)NHCH(C(O)OC₂H₅)₂ (R = H, Me, Cl) and 2-bromobenzaldehydes e.g., 2-bromo-4-chlorobenzaldehyde was developed for the synthesis of isoindolo[1,2-b]quinazoline derivs e.g., I. The quinazoline was first catalyzed by CuI, followed by a noteworthy α-arylation reaction under Pd and ligand-free conditions in the presence of Cs₂CO₃.

5392-10-9, 2-Bromo-4,5-dimethoxybenzaldehyde is a useful research compound. Its molecular formula is C9H9BrO3 and its molecular weight is 245.07 g/mol. The purity is usually 95%.
2-Bromo-4,5-dimethoxybenzaldehyde is a synthetic compound that has been shown to be an effective agent for inducing apoptosis in leukemia cells. It is an efficient method for synthesizing the compound and ha2-Bromo-4,5-dimethoxybenzaldehyde induces cell death by topoisomerase-mediated DNA cleavage, which results in chromosomal fragmentation and high levels of reactive oxygen species in the cell., Application of C9H9BrO3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic compounds having carbon bonded to bromine are called organic bromides. 5392-10-9, formula is C9H9BrO3, Name is 2-Bromo-4,5-dimethoxybenzaldehyde. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. SDS of cas: 5392-10-9.

Zhao, Yang;Ku, Chuen-Fai;Xu, Xin-Ya;Tsang, Nga-Yi;Zhu, Yu;Zhao, Chen-Liang;Liu, Kang-Lun;Li, Chuang-Chuang;Rong, Lijun;Zhang, Hong-Jie research published 《 Stable Axially Chiral Isomers of Arylnaphthalene Lignan Glycosides with Antiviral Potential Discovered from Justicia procumbens》, the research content is summarized as follows. Arylnaphthalene lignans (ANLs) were known to have axial chirality due to the biphenyl skeleton with hindered rotation at the single bond. However, the stable ANL atropisomers have not been isolated from nature until the present study. Phytochem. separation of the methanol extract of the stems and barks of Justicia procumbens led to the isolation of 11 ANL glycosides including four pairs of new atropisomers with stable confirmations at room temperature Their structures were deduced from elucidation of the extensive spectral data, and their absolute configurations were determined by the CD, electronic CD, and X-ray methods as well as the total synthesis of one pair of the atropisomers. The ANL compounds were evaluated for their antiviral potential, and it was found that they displayed great antiviral activity discrepancy between a pair of atropisomers due to the geometric orientation. The 1′P-oriented atropisomers showed much more significant antiviral potency than their corresponding 1′M-oriented counterparts. The biol. activity discrepancy caused by the axial chirality will not only inspire synthetic design of novel ANL atropisomers to enrich the structural diversity, but also provide important hints to direct the synthetic approaches toward the antiviral drug development of ANL compounds

5392-10-9, 2-Bromo-4,5-dimethoxybenzaldehyde is a useful research compound. Its molecular formula is C9H9BrO3 and its molecular weight is 245.07 g/mol. The purity is usually 95%.
2-Bromo-4,5-dimethoxybenzaldehyde is a synthetic compound that has been shown to be an effective agent for inducing apoptosis in leukemia cells. It is an efficient method for synthesizing the compound and ha2-Bromo-4,5-dimethoxybenzaldehyde induces cell death by topoisomerase-mediated DNA cleavage, which results in chromosomal fragmentation and high levels of reactive oxygen species in the cell., SDS of cas: 5392-10-9

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 5392-10-9, formula is C9H9BrO3, Name is 2-Bromo-4,5-dimethoxybenzaldehyde, Recommanded Product: 2-Bromo-4,5-dimethoxybenzaldehyde

Zhan, Yanling;Dai, Changhui;Zhu, Zitong;Liu, Ping;Sun, Peipei research published 《 Electrochemical Decarboxylative Cyclization of α-Amino-Oxy Acids to Access Phenanthridine Derivatives》, the research content is summarized as follows. In this work, a method via electrochem. decarboxylative cyclization of α-amino-oxy acids to access phenanthridine derivatives, e.g., I, was developed. This reaction proceeded through iminyl radical formation cascade intramol. cyclization from readily available materials under environmentally friendly conditions. A wide range of phenanthridine derivatives were obtained in moderate to high yields.

Recommanded Product: 2-Bromo-4,5-dimethoxybenzaldehyde, 2-Bromo-4,5-dimethoxybenzaldehyde is a useful research compound. Its molecular formula is C9H9BrO3 and its molecular weight is 245.07 g/mol. The purity is usually 95%.
2-Bromo-4,5-dimethoxybenzaldehyde is a synthetic compound that has been shown to be an effective agent for inducing apoptosis in leukemia cells. It is an efficient method for synthesizing the compound and ha2-Bromo-4,5-dimethoxybenzaldehyde induces cell death by topoisomerase-mediated DNA cleavage, which results in chromosomal fragmentation and high levels of reactive oxygen species in the cell., 5392-10-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 5392-10-9, formula is C9H9BrO3, Name is 2-Bromo-4,5-dimethoxybenzaldehyde. Organobromine compounds have fallen under increased scrutiny for their environmental impact., COA of Formula: C9H9BrO3.

Zhang, Dejiang;Tang, Ting;Zhang, Zhao;Le, Liyuan;Xu, Zhi;Lu, Hao;Tong, Zhou;Zeng, Dishu;Wong, Wai-Yeung;Yin, Shuang-Feng;Ghaderi, Arash;Kambe, Nobuaki;Qiu, Renhua research published 《 Nickel- and Palladium-Catalyzed Cross-Coupling of Stibines with Organic Halides: Site-Selective Sequential Reactions with Polyhalogenated Arenes》, the research content is summarized as follows. Herein, the authors disclose a general and efficient method for the synthesis of Sb-aryl and Sb-alkyl stibines by the Ni-catalyzed cross-coupling of halostibines with organic halides. The synthesized Sb-aryl stibines couple with aryl halides to give biaryls efficiently via Pd catalysis. Sequential reactions of stibines with polyhalogenated arenes bearing active C-I/C-Br sites and inactive C-Cl sites successfully proceeded, giving a variety of complex mols. with good site selectivity. Drugs such as diflunisal and fenbufen, as well as a fenofibrate derivative, were synthesized on gram scales in good yields, together with the high recovery of chlorostibine. Also, catalytic mechanisms are proposed based on the results of control experiments

COA of Formula: C9H9BrO3, 2-Bromo-4,5-dimethoxybenzaldehyde is a useful research compound. Its molecular formula is C9H9BrO3 and its molecular weight is 245.07 g/mol. The purity is usually 95%.
2-Bromo-4,5-dimethoxybenzaldehyde is a synthetic compound that has been shown to be an effective agent for inducing apoptosis in leukemia cells. It is an efficient method for synthesizing the compound and ha2-Bromo-4,5-dimethoxybenzaldehyde induces cell death by topoisomerase-mediated DNA cleavage, which results in chromosomal fragmentation and high levels of reactive oxygen species in the cell., 5392-10-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 5392-10-9, formula is C9H9BrO3, Name is 2-Bromo-4,5-dimethoxybenzaldehyde, Application of C9H9BrO3

Zhang, Fulin;Zhao, Ruihua;Zhu, Lei;Yu, Yinghua;Liao, Saihu;Wang, Zhi-Xiang;Huang, Xueliang research published 《 Divergent isoindolinone synthesis through palladium-catalyzed isocyanide bridging C-H activation》, the research content is summarized as follows. An isocyanide-bridging C-H activation through the formation of a five-membered palladacycle was reported. As such, a proximal C-H bond in aldehyde moiety is activated selectively. The subsequent palladium shift and intramol. C=N bond insertion construct a valuable isoindolinone framework. Compared with conventional isocyanide-promoted C-H bond activation, both carbon and nitrogen atoms in isocyanide are engaged in new bond formations. Three types of isoindolinones I [R = t-Bu, cyclohexyl, Bn, etc.; R¹ = H, CN; R² = H, Bn, 2H-1,3-benzodioxol-5-ylmethyl, etc.; R³ = H, F, OMe, etc.; R⁴ = H, Cl, NH₂, etc.; R⁵ = H, Me, OTs, etc.; -R₄R₅– = -OCH₂O-; -R₅R₆– = -(CH)₄-; R⁶ = H, OMe, etc.] can be obtained selectively by variations of the reaction conditions. Mechanistic studies shed light on the reaction pathways. The synthetic potential of current methodol. is demonstrated by providing concise routes to key intermediates of indoprofen, indobufen, aristolactams, lennoxamine, and falipamil.

Application of C9H9BrO3, 2-Bromo-4,5-dimethoxybenzaldehyde is a useful research compound. Its molecular formula is C9H9BrO3 and its molecular weight is 245.07 g/mol. The purity is usually 95%.
2-Bromo-4,5-dimethoxybenzaldehyde is a synthetic compound that has been shown to be an effective agent for inducing apoptosis in leukemia cells. It is an efficient method for synthesizing the compound and ha2-Bromo-4,5-dimethoxybenzaldehyde induces cell death by topoisomerase-mediated DNA cleavage, which results in chromosomal fragmentation and high levels of reactive oxygen species in the cell., 5392-10-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 5392-10-9, formula is C9H9BrO3, Name is 2-Bromo-4,5-dimethoxybenzaldehyde. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Recommanded Product: 2-Bromo-4,5-dimethoxybenzaldehyde.

Zhang, Jitan;Xu, Qiaoqiao;Fan, Jian;Zhou, Lan;Liu, Nannan;Zhu, Li;Wu, Jiaping;Xie, Meihua research published 《 Pd(II)-Catalyzed enantioconvergent twofold C-H annulation to access atropisomeric aldehydes: a platform for diversity-oriented-synthesis》, the research content is summarized as follows. Herein, the first Pd(II)-catalyzed atroposelective dual C-H annulative strategy for the assembly of axially chiral aldehyde frameworks such as I [R = Me, Et, i-Pr] using com. available amino acid as the transient auxiliary and chiral pool was presented. This reaction accommodated a broad substrate scope to give atropisomeric aldehydes bearing both C-C and N-C chiral axes in good yields (up to 95%) with excellent enantioinduction (up to 99%). The utility of this synthetic methodol. was testified by various practical late-stage transformations, thereby accomplishing diversity-oriented synthesis of structurally diverse biaryl atropisomers and several functionalized axially chiral species such as bifunctional organocatalysts. Moreover, a series of mechanistic studies had provided more details for this catalytic transformation.

Recommanded Product: 2-Bromo-4,5-dimethoxybenzaldehyde, 2-Bromo-4,5-dimethoxybenzaldehyde is a useful research compound. Its molecular formula is C9H9BrO3 and its molecular weight is 245.07 g/mol. The purity is usually 95%.
2-Bromo-4,5-dimethoxybenzaldehyde is a synthetic compound that has been shown to be an effective agent for inducing apoptosis in leukemia cells. It is an efficient method for synthesizing the compound and ha2-Bromo-4,5-dimethoxybenzaldehyde induces cell death by topoisomerase-mediated DNA cleavage, which results in chromosomal fragmentation and high levels of reactive oxygen species in the cell., 5392-10-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Vinyl bromides undergo the Heck reaction, which involves C-C coupling with alkene to give substituted alkenes. 5392-10-9, formula is C9H9BrO3, Name is 2-Bromo-4,5-dimethoxybenzaldehyde. Methyl bromide is a precursor in the manufacture of several chemicals and is employed as a soil sterilant, mainly for seed production. Recommanded Product: 2-Bromo-4,5-dimethoxybenzaldehyde.

Yu, Shu-Yan;Gao, Li-Hong;Wu, Jing-Xin;Lan, Hong-Bing;Ma, Yi;Yin, Zhi-Gang research published 《 Regio- and stereoselective intramolecular hydroalkoxylation of aromatic alkynols: an access to dihydroisobenzofurans under transition-metal-free conditions》, the research content is summarized as follows. An efficient, transition-metal-free method to synthesize dihydroisobenzofuran derivatives via intramol. hydroalkoxylation of aromatic alkynols with the promotion of cesium carbonate has been developed. The reaction proceeds regioselectively with exclusive formation of 5-exo-dig product, and only Z-isomer of the new generated double bond is observed This new protocol features with milder reaction conditions, more convenient operation and satisfactory selectivities.

Recommanded Product: 2-Bromo-4,5-dimethoxybenzaldehyde, 2-Bromo-4,5-dimethoxybenzaldehyde is a useful research compound. Its molecular formula is C9H9BrO3 and its molecular weight is 245.07 g/mol. The purity is usually 95%.
2-Bromo-4,5-dimethoxybenzaldehyde is a synthetic compound that has been shown to be an effective agent for inducing apoptosis in leukemia cells. It is an efficient method for synthesizing the compound and ha2-Bromo-4,5-dimethoxybenzaldehyde induces cell death by topoisomerase-mediated DNA cleavage, which results in chromosomal fragmentation and high levels of reactive oxygen species in the cell., 5392-10-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary