Category: 518-67-2

Jia, Lijuan published the artcileQSAR models for oxidative degradation of organic pollutants in the Fenton process, COA of Formula: C20H18BrN3, the publication is Journal of the Taiwan Institute of Chemical Engineers (2015), 140-147, database is CAplus.

Fenton oxidation is an advanced treatment process used to remove organic pollutants in wastewater. In this study, quant. structure activity relationship (QSAR) models for Fenton process were developed with reaction rate constants of organic compounds as the dependent variable. To establish optimum QSAR models, reaction rate constants of 33 kinds of organic substances were determined and 13 mol. descriptors were selected. The mol. descriptors were calculated by Hyperchem, Gaussian 09 and Dmol³ software for each organic compound The optimum QSAR model for predicting the rate constants consists of three descriptors, SAG, f(0)_n and EGAP. Among them, SAG appears most critical in determining rate constants A set of 26 compounds was used as training set to develop models and 7 compounds was used as test set for external validation. The prediction accuracy of the recommended model was tested using the leave-one-out cross validation procedure, validation through an external test set and the Y-randomization evaluation technique. The domain of applicability was finally determined to identify the reliable predictions. The results indicated that the proposed model proved to have significant predictive potential of reaction rate constants in Fenton process.

Journal of the Taiwan Institute of Chemical Engineers published new progress about 518-67-2. 518-67-2 belongs to bromides-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Salt,Amine,Benzene, name is Dimidium bromide, and the molecular formula is C20H18BrN3, COA of Formula: C20H18BrN3.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Ormerod, W. E. published the artcileGranules and other changes in phase-contrast appearance produced by chemotherapeutic agents in trypanosomes, COA of Formula: C20H18BrN3, the publication is British Journal of Pharmacology and Chemotherapy (1963), 21(2), 259-72, database is CAplus and MEDLINE.

The morphological changes produced by 4 series of organic trypanocidal drugs were studied by quant. and by qual. methods using phase-contrast and fluorescence microscopy. Basic drugs (hydroxystilbamidine, quinapyramine, and homidium) were absorbed rapidly into the region of the kinetoplast; acidic drugs (suramin and related compounds) did not affect this region. Faint granules, which were present in some trypanosomes before the administration of drugs, absorbed the drugs and increased in contrast relative to the cytoplasm. Hydroxystilbamidine, quinapyramine, and related compounds, and possibly also suramin produced addnl. granules which did not contain drug. These addnl. granules are similar to the granules (volutin granules) which occur in trypanosome infections (not treated with drugs) when trypanosomes are about to be cleared from the blood. Homidium did not produce addnl. granules.

British Journal of Pharmacology and Chemotherapy published new progress about 518-67-2. 518-67-2 belongs to bromides-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Salt,Amine,Benzene, name is Dimidium bromide, and the molecular formula is C20H18BrN3, COA of Formula: C20H18BrN3.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Cao, Jingjiao published the artcileOrdered Porous Poly(ionic liquid) Crystallines: Spacing Confined Ionic Surface Enhancing Selective CO₂ Capture and Fixation, Category: bromides-buliding-blocks, the publication is ACS Applied Materials & Interfaces (2019), 11(6), 6031-6041, database is CAplus and MEDLINE.

Porous poly(ionic liquid)s (PPILs) combine the features of porous materials, polymers, and ionic liquids (ILs) or their derivatives, but they are normally of amorphous structure with disordered pores. Here, we report the facile synthesis of ordered porous poly(ionic liquid) crystallines (OPICs, specialized as a kind of PPIL analogs) with diverse and adjustable framework IL moieties through the Schiff base condensation of IL-derived ionic salts and neutral monomers. Ternary monomer mixtures are employed to artistically control the chem. composition and pore configurations. Compact at. packing was achieved to give spacing confined ionic surface with strong CO₂ affinity. Through monomer control, OPICs exhibit high CO₂ uptakes with excellent CO₂/N₂(CH₄) selectivities and efficiently implement CO₂ fixation through catalyzing epoxides cycloaddition under down to ambient conditions.

ACS Applied Materials & Interfaces published new progress about 518-67-2. 518-67-2 belongs to bromides-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Salt,Amine,Benzene, name is Dimidium bromide, and the molecular formula is C20H18BrN3, Category: bromides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Kode, Kranthi published the artcileRaman labeled nanoparticles: characterization of variability and improved method for unmixing, Synthetic Route of 518-67-2, the publication is Journal of Raman Spectroscopy (2012), 43(7), 895-905, database is CAplus and MEDLINE.

Raman spectroscopy can differentiate the spectral fingerprints of many mols., resulting in potentially high multiplexing capabilities of Raman-tagged nanoparticles. However, an accurate quant. unmixing of Raman spectra is challenging because of potential overlaps between Raman peaks from each mol., as well as slight variations in the location, height, and width of very narrow peaks. If not accounted for properly, even minor fluctuations in the spectra may produce significant error that will ultimately result in poor unmixing accuracy. The objective of our study was to develop and validate a math. model of the Raman spectra of nanoparticles to unmix the contributions from each nanoparticle allowing simultaneous quantitation of several nanoparticle concentrations during sample characterization. We developed and evaluated an algorithm for quant. unmixing of the spectra called narrow peak spectral algorithm (NPSA). Using NPSA, we were able to successfully unmix Raman spectra of up to seven Raman nanoparticles after correcting for spectral variations of 30% intensity and shifts in peak locations of up to 10 cm^-1, which is equivalent to 50% of the full width at half maximum (FWHM). We compared the performance of NPSA to the conventional least squares (LS) anal. Error in the NPSA is approx. 50% lower than in the LS. The error in estimating the relative contributions of each nanoparticle with the use of the NPSA are in the range of 10-16% for equal ratios and 13-19% for unequal ratios for the unmixing of seven composite organic-inorganic nanoparticles (COINs); whereas, the errors from using the traditional LS approach were in the range of 25-38% for equal ratios and 45-68% for unequal ratios. Here, we report for the first time the quant. unmixing of seven nanoparticles with a maximum root mean square of the percentage error (RMS%) error of less than 20%.

Journal of Raman Spectroscopy published new progress about 518-67-2. 518-67-2 belongs to bromides-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Salt,Amine,Benzene, name is Dimidium bromide, and the molecular formula is C20H18BrN3, Synthetic Route of 518-67-2.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Nakazato, Ryosuke published the artcileFactors for the emission enhancement of dimidium in specific media such as in DNA and on a clay surface, Computed Properties of 518-67-2, the publication is Physical Chemistry Chemical Physics (2019), 21(41), 22732-22739, database is CAplus and MEDLINE.

Dimidium (3,8-diamino-5-methyl-6-phenylphenanthridinium: NH₂PhP) is a well-known fluorophore as a DNA probe, although its fluorescence enhancement mechanism is not clear. In this study, we investigated the fluorescence enhancement mechanism of NH₂PhP on a clay surface by observing the fluorescence behavior. Four systematically selected phenanthridinium derivatives (PDs): NH₂PhP, 3,8-bisdimethylamino-5-methyl-6-phenylphenanthridinium (NMe₂PhP), 5-methyl-6-phenylphenanthridinium (PhP) and 5-methylphenanthridinium (P) and synthetic clay were used as guest and host materials, resp. It was revealed that the suppression of hydrogen bonding with water (N-HOH or NH-OH₂) is the dominant factor for the fluorescence enhancement on the clay surface for NH₂PhP and NMe₂PhP. In addition, judging from the fluorescence enhancement for NH₂PhP, NMe₂PhP and PhP and no fluorescence enhancement for P on the clay surface, the suppression of rotation of the Ph ring was indicated to make a partial contribution to the fluorescence enhancement mechanism. Because the fluorescence enhancement behavior was quite similar on the clay surface and in DNA, the obtained results afford an important clue to discuss the fluorescence enhancement mechanism of NH₂PhP in DNA.

Physical Chemistry Chemical Physics published new progress about 518-67-2. 518-67-2 belongs to bromides-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Salt,Amine,Benzene, name is Dimidium bromide, and the molecular formula is C20H18BrN3, Computed Properties of 518-67-2.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Ames, James R. published the artcileMode of action of antiprotozoan agents. Electron transfer and oxy radicals, Product Details of C20H18BrN3, the publication is Life Sciences (1987), 41(16), 1895-902, database is CAplus and MEDLINE.

Cyclic voltammetry data were obtained for most of the main classes of antiprotozoan agents, specifically, nitroheterocycles, quinones, metal complexes and derivatives, iminium-type ions, and azo compounds The reductions were generally reversible in the range of -0.3 to -0.9 V. Catalytic production of oxidative pressure from redox cycling involving oxygen is believed to be an important mode of action by the medicinal agents. Literature data contribute support.

Life Sciences published new progress about 518-67-2. 518-67-2 belongs to bromides-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Salt,Amine,Benzene, name is Dimidium bromide, and the molecular formula is C20H18BrN3, Product Details of C20H18BrN3.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Ullrich, K. J. published the artcileBisubstrates: Substances that interact with renal contraluminal organic anion and organic cation transport systems. I. Amines, piperidines, piperazines, azepines, pyridines, quinolines, imidazoles, thiazoles, guanidines and hydrazines, Application of Dimidium bromide, the publication is Pfluegers Archiv (1993), 425(3-4), 280-99, database is CAplus and MEDLINE.

The authors examined the renal transport of nine classes of N-containing substances by the contraluminal organic anion (p-amminohippurate) and contraluminal organic cation (N’-methylnicotinamide and tetra-Et ammonium) transport systems. Many substrates interacted with both systems if they were sufficiently hydrophobic and had groups that were sufficiently electron-attracting.

Pfluegers Archiv published new progress about 518-67-2. 518-67-2 belongs to bromides-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Salt,Amine,Benzene, name is Dimidium bromide, and the molecular formula is C12H14O2, Application of Dimidium bromide.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Troeger, Rikard published the artcileWhat′s in the water? – Target and suspect screening of contaminants of emerging concern in raw water and drinking water from Europe and Asia, Recommanded Product: Dimidium bromide, the publication is Water Research (2021), 117099, database is CAplus and MEDLINE.

There is growing worry that drinking water can be affected by contaminants of emerging concern (CECs), potentially threatening human health. In this study, a wide range of CECs (n = 177), including pharmaceuticals, pesticides, perfluoroalkyl substances (PFASs) and other compounds, were analyzed in raw water and in drinking water collected from drinking water treatment plants (DWTPs) in Europe and Asia (n = 13). The impact of human activities was reflected in large numbers of compounds detected (n = 115) and high variation in concentrations in the raw water (range 15-7995 ng L-1 for ∑177CECs). The variation was less pronounced in drinking water, with total concentration ranging from 35 to 919 ng L-1. Treatment efficiency was on average 65 ± 28%, with wide variation between different DWTPs. The DWTP with the highest ∑CEC concentrations in raw water had the most efficient treatment procedure (average treatment efficiency 89%), whereas the DWTP with the lowest ∑177CEC concentration in the raw water had the lowest average treatment efficiency (2.3%). Suspect screening was performed for 500 compounds ranked high as chems. of concern for drinking water, using a prioritisation tool (SusTool). Overall, 208 features of interest were discovered and three were confirmed with reference standards There was co-variation between removal efficiency in DWTPs for the target compounds and the suspected features detected using suspect screening, implying that removal of known contaminants can be used to predict overall removal of potential CECs for drinking water production Our results can be of high value for DWTPs around the globe in their planning for future treatment strategies to meet the increasing concern about human exposure to unknown CECs present in their drinking water.

Water Research published new progress about 518-67-2. 518-67-2 belongs to bromides-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Salt,Amine,Benzene, name is Dimidium bromide, and the molecular formula is C23H28N2O4, Recommanded Product: Dimidium bromide.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Ramu, Avner published the artcileReduced ouabain-sensitive potassium entry as a possible mechanism of multidrug-resistance in P388 cells, Application of Dimidium bromide, the publication is Biochemical Pharmacology (1991), 42(9), 1699-704, database is CAplus and MEDLINE.

Multidrug-resistant P388 cells were found to be resistant also to a variety of ammonium, phosphonium and arsonium compounds As previously shown for anthracyclines and vinca alkaloids, the resistance to the permanently charged lipophilic cationic compounds could be circumvented by verapamil. Relative to drug-sensitive cells, K⁺ uptake and plasma membrane Mg-ATPase activity in multidrug-resistant cells are ouabain resistant. The intracellular K⁺ concentration in drug-resistant cells is maintained at a normal level by increased activity of the furosemide sensitive transport system. It is suggested that the reduced activity of the electrogenic Na⁺-K⁺ pump in multidrug-resistant cells could result in a lower transmembrane potential and therefore reduced accumulation of cationic lipophilic compounds

Biochemical Pharmacology published new progress about 518-67-2. 518-67-2 belongs to bromides-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Salt,Amine,Benzene, name is Dimidium bromide, and the molecular formula is C20H18BrN3, Application of Dimidium bromide.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Lowy, Dan A. published the artcileA new high-efficiency reagent for the potentiometry of cationic surfactants, Related Products of bromides-buliding-blocks, the publication is Process Control and Quality (1993), 4(2), 125-37, database is CAplus.

A new heteropolyanionic reagent has been used for the accurate determination of quaternary ammonium salts (QAS) in various matrixes containing strongly interfering species. The octapotassium 1-cobalto(II)[1-aqua]-1-molybdo-16-tungsto-2-phosphate (HPA) is a successful titrant of several alkyltrimethylammonium salts (with an alkyl chain of C_12-18), both in the potentiometric and the two-phase titration procedure. In order to prove the high efficiency of the proposed reagent, comparative titrations have been carried out for hexadecyltrimethylammonium bromide with HPA, sodium tetraphenylborate (TFB) and sodium dodecylsulfate (DDS). The dimidium bromide and disulfine VN 150 indicator mixture has been utilized in two-phase titrations, while the endpoint of the potentiometric titrations was detected by means of a QAS-selective liquid-membrane electrode. The relative error of the average of eight titrations by means of the three reagents decreased in the order TFB > DDS > HPA, corresponding to the increase of the association equilibrium constant: [(CH₃)₃RN]₈HPA·19H₂O > [(CH₃)₃RN]DDS > [(CH₃)₃RN]TFB.

Process Control and Quality published new progress about 518-67-2. 518-67-2 belongs to bromides-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Salt,Amine,Benzene, name is Dimidium bromide, and the molecular formula is C20H18BrN3, Related Products of bromides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary