Category: 4224-70-8

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 4224-70-8, formula is C6H11BrO2, The most pervasive is the naturally produced bromomethane. Application In Synthesis of 4224-70-8

Xie, Xiu-Ying;Jiang, Wei-Tao;Xiao, Bin research published 《 Alkyl Carbagermatrane Enabled Synthesis of Seven-Membered Carbocycle-Fused Aromatics through Catellani Strategy》, the research content is summarized as follows. Synthesis of seven-membered carbocycle-fused aromatics was realized by Catellani reaction using terminally brominated alkyl carbagermatranes through intermol. cyclization manner. Various functional groups were well tolerated and this transformation was also expanded to the synthesis of carbocycles of other size. The utility of the above method was demonstrated by modification of natural product derivatives and synthesis of bioactive mols.

Application In Synthesis of 4224-70-8, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., 4224-70-8.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic compounds having carbon bonded to bromine are called organic bromides. 4224-70-8, formula is C6H11BrO2, Name is 6-Bromohexanoic acid. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Related Products of 4224-70-8.

Wulkesch, Christian;Czekelius, Constantin research published 《 Straightforward Synthesis of Fluorinated Enals via Photocatalytic α-Perfluoroalkenylation of Aldehydes》, the research content is summarized as follows. The (Per)fluorinated substances represent an important compound class with regard to drug design and material chem. A mild, operationally simple, and inexpensive photocatalytic perfluoroalkenylation reaction giving tetrasubstituted highly electron-deficient enals RC(R¹)=C(F)R² (R = [2-(2,4-dinitrophenyl)hydrazin-1-ylidene]methyl, hydroxymethyl, CHO; R¹ = n-hexyl, benzyl, cyclohexyl, etc.; R² = heptafluoropropyl, undecafluoropentyl, pentadecafluoroheptyl, ethoxycarbonyl), straight from aldehydes R¹CH₂CHO was found. This one-step reaction tolerates various functional groups and can be applied to a wide range of substrates giving the products in yields of 52-84%.

4224-70-8, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., Related Products of 4224-70-8

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Dehydrobromination, Grignard reactions, reductive coupling, Wittig reaction, and several nucleophilic substitution reactions are some of the principal reactions which involve organic bromides. 4224-70-8, formula is C6H11BrO2, Name is 6-Bromohexanoic acid. Organic compounds having carbon bonded to bromine are called organic bromides. Synthetic Route of 4224-70-8.

Xi, Xiaoxiang;Luo, Yixin;Li, Weirong;Xu, Minghao;Zhao, Hongping;Chen, Yukun;Zheng, Songlin;Qi, Xiaotian;Yuan, Weiming research published 《 From Esters to Ketones via a Photoredox-Assisted Reductive Acyl Cross-Coupling Strategy》, the research content is summarized as follows. A method was developed for ketone synthesis via a photoredox-assisted reductive acyl cross-coupling (PARAC) using a nickel/photoredox dual-catalyzed cross-electrophile coupling of two different carboxylic acid esters. A variety of aryl, 1°, 2°, 3°-alkyl 2-pyridyl esters could act as acyl electrophiles while N-(acyloxy)phthalimides (NHPI esters) act as 1°, 2°, 3°-radical precursors. Our PARAC strategy provides an alternative and reliable way to synthesize various sterically congested 3°-3°, 3°-2°, and aryl-3° ketones under mild and highly unified conditions, which have been otherwise difficult to access. The combined exptl. and computational studies identified a Ni0/NiI/NiIII pathway for ketone formation.

4224-70-8, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., Synthetic Route of 4224-70-8

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 4224-70-8, formula is C6H11BrO2, The most pervasive is the naturally produced bromomethane. Recommanded Product: 6-Bromohexanoic acid

Xia, Lei;Tian, Jia;Yue, Tao;Cao, Hongliang;Chu, Ju;Cai, Haibo;Zhang, Weian research published 《 Pillar[5]arene-Based Acid-Triggered Supramolecular Porphyrin Photosensitizer for Combating Bacterial Infections and Biofilm Dispersion》, the research content is summarized as follows. The treatment of pathogenic bacterial infection has long been the most serious threat to human life and attracted widespread attention. Herein, a supramol. photosensitizer platform based on carboxylatopillar[5]arene (CP5) and tetrafluorophenyl porphyrin functionalized with a quaternary ammonium group (TFPP-QA) for combating bacteria and dispersing biofilm via photodynamic treatment is constructed. By introducing the host macrocycle CP5 and host-guest interaction, the supramol. photosensitizer has great biocompatibility and acid responsiveness. On the one hand, the acid-triggered dissociation of TFPP-QA/CP5 could induce the porphyrin photosensitizer to target bacterial cells and disrupt the charge balance of bacterial membranes, enhance the permeability of the bacterial membrane. On the other hand, the TFPP-QA/CP5 antibacterial platform possesses superb reactive oxygen species (ROS) generation capability under light irradiation, leading to enhanced photodynamic antibacterial efficacy. The in vitro and in vivo studies show that the supramol. photosensitizers exhibit high antibacterial efficiency and biofilm dissipation effect under 660 nm light irradiation Therefore, it is anticipated that the rational design and integration of photosensitizers and quaternary ammonium compounds through the supramol. strategy would provide a promising prospect for clin. photodynamic antimicrobial therapy.

Recommanded Product: 6-Bromohexanoic acid, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., 4224-70-8.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 4224-70-8, formula is C6H11BrO2, Name is 6-Bromohexanoic acid. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Category: bromides-buliding-blocks.

Wu, Bocheng;Payero, Benny;Taylor, Sydney;Oyelere, Adegboyega K. research published 《 Discovery of novel STAT3 DNA binding domain inhibitors》, the research content is summarized as follows. STAT3 is a pro-oncogenic transcription factor. Pyrimethamine (PYM) is a STAT3 inhibitor that suppresses the proliferation of some cancer cells through downregulation of STAT3 target proteins. We have used structure-based tools to design novel PYM-based compounds Intracellular target validation studies revealed that representative compounds 11b-d and 15a downregulate STAT3 downstream proteins and inhibit STAT3 DNA binding domain (DBD). Relative to PYM, a cohort of these compounds are >100-fold more cytotoxic to cancer cells with constitutively active (high pSTAT3) and basal (low pSTAT3) STAT3 signaling, suggesting that STAT3 DBD inhibition is deleterious to the proliferation of cancer cells with low and high pSTAT3 levels. These are promising leads for further preclin. evaluation as therapeutic agents for STAT3-dependent cancers.

Category: bromides-buliding-blocks, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., 4224-70-8.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 4224-70-8, formula is C6H11BrO2, Name is 6-Bromohexanoic acid. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Related Products of 4224-70-8.

Wang, Tianlin;Zheng, Yue;Yu, Guangren;Chen, Xiaochun research published 《 Glycolysis of polyethylene terephthalate: Magnetic nanoparticle CoFe₂O₄ catalyst modified using ionic liquid as surfactant》, the research content is summarized as follows. The catalytic effect of nanoparticles was significantly affected by its size and surface property. In this work, a series of ionic liquids were synthesized and used as surfactant to modify CoFe₂O₄ MNP. XRD, FT-IR, TEM and VSM were performed to characterize modified CoFe₂O₄. The modified CoFe₂O₄ MNP with average size of 7 nm was obtained and it was so well dispersed in ethylene glycol that ethylene glycol based magnetic fluid was obtained. Modified CoFe₂O₄ MNP was used as catalyst for glycolysis of PET and showed excellent catalytic effect. The influence of ionic liquids surfactant and exptl. factors on glycolysis were investigated. Under optimal condition, PET (5 g), catalyst (CoFe2O4/C10-OAC, 0.1 g) and EG (25 g) at 195°C for 2.5 h, the PET conversion was 100% and BHET yield was 95.4%. More importantly, this catalyst can be collected by external magnetic field and its catalytic effect did not obviously decrease after it was reused for ten times. This work provided a new type of highly efficient catalyst of glycolysis of PET.

4224-70-8, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., Related Products of 4224-70-8

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 4224-70-8, formula is C6H11BrO2, Name is 6-Bromohexanoic acid. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Application of C6H11BrO2.

Wang, Yangjian;Zheng, Junshui;Lin, Jian;Ye, Kai;Wei, Peng research published 《 Mitochondria-targeting and ROS-responsive nanocarriers via amphiphilic TPP-PEG-TK-Ce6 for nanoenabled photodynamic therapy》, the research content is summarized as follows. Designing targeted-delivering and stimuli-responsive nanocarriers for photodynamic therapy (PDT) is an appealing method, especially, targeting delivery of photosensitizers to mitochondria as the most sensitive cellular organelles to reactive oxygen species (ROS) could significantly enhance the therapeutic efficacy of PDT. In this study, we synthesized triphenylphosphonium bonded PEG-NH₂ (TPP-PEG-NH₂) and bridged to chlorin e6 (Ce6) via thioketal (TK) linkage to obtain red light-triggered, amphiphilic copolymer (TPP-PEG-TK-Ce6), which could self-assemble into micelles with an average size of 160 nm and zeta potential of +20.1 mV. The in vitro release behavior of TPP-PEG-TK-Ce6 nanocarriers showed a light-activated way and was dependent on the H₂O₂ concentration TPP-PEG-TK-Ce6 nanocarriers exhibited high cytotoxicity against C6 cells with illumination. Confocal laser scanning microscopy observation indicated that TPP-PEG-TK-Ce6 nanocarriers were efficiently internalized into the mitochondrion of C6 cells, released Ce6 via light activated. By contrast, in the case of TPP-PEG-NH₂ directly bonded Ce6 (TPP-PEG-Ce6) nanocarriers, little Ce6 was found in the mitochondrion. The stronger fluorescence in the mitochondrion of TPP-PEG-TK-Ce6 nanocarriers originated from the mitochondrial-targeting capability of TPP and the cleavage of TK linkages activated by light irradiation, which greatly improved the cellular uptake of TPP-PEG-TK-Ce6 nanocarriers and released more Ce6 in the mitochondrion. This work provided a facile strategy to improve PDT efficacy.

4224-70-8, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., Application of C6H11BrO2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 4224-70-8, formula is C6H11BrO2, Name is 6-Bromohexanoic acid. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Name: 6-Bromohexanoic acid.

Wang, Hao;Jung, Hoimin;Song, Fangfang;Zhu, Shiyang;Bai, Ziqian;Chen, Danye;He, Gang;Chang, Sukbok;Chen, Gong research published 《 Nitrene-mediated intermolecular N-N coupling for efficient synthesis of hydrazides》, the research content is summarized as follows. N-N linkages are found in many natural compounds and endow fascinating structural and functional properties. In comparison to the myriad methods for the construction of C-N bonds, chem. for N-N coupling, especially in an intermol. fashion, remains underdeveloped. Here, we report a nitrene-mediated intermol. N-N coupling of dioxazolones and arylamines under iridium or iron catalysis. These reactions offer a simple and efficient method for the synthesis of various hydrazides from readily available carboxylic acid and amine precursors. Although the Ir-catalyzed conditions usually give higher N-N coupling yield than the Fe-catalyzed conditions, the reactions of sterically more demanding dioxazolones derived from α-substituted carboxylic acids work much better under the Fe-catalyzed conditions. Mechanistic studies revealed that the nitrogen atom of Ir acyl nitrene intermediates has strong electrophilicity and can undergo nucleophilic attack with arylamines with the assistance of Cl···HN hydrogen bonding to form the N-N bond with high efficiency and chemoselectivity.

Name: 6-Bromohexanoic acid, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., 4224-70-8.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 4224-70-8, formula is C6H11BrO2, Name is 6-Bromohexanoic acid, Application of C6H11BrO2

Volpato, Giulia Alice;Colusso, Elena;Paoloni, Lorenzo;Forchetta, Mattia;Sgarbossa, Francesco;Cristino, Vito;Lunardon, Marco;Berardi, Serena;Caramori, Stefano;Agnoli, Stefano;Sabuzi, Federica;Umari, Paolo;Martucci, Alessandro;Galloni, Pierluca;Sartorel, Andrea research published 《 Artificial photosynthesis: photoanodes based on polyquinoid dyes onto mesoporous tin oxide surface》, the research content is summarized as follows. Dye-sensitized photoelectrochem. cells represent an appealing solution for artificial photosynthesis, aimed at the conversion of solar light into fuels or commodity chems. Extensive efforts have been directed towards the development of photoelectrodes combining semiconductor materials and organic dyes; the use of mol. components allows to tune the absorption and redox properties of the material. Recently, we have reported the use of a class of pentacyclic quinoid organic dyes (KuQuinone) chemisorbed onto semiconducting tin oxide as photoanodes for water oxidation In this work, we investigate the effect of the SnO₂ semiconductor thickness and morphol. and of the dye-anchoring group on the photoelectrochem. performance of the electrodes. The optimized materials are mesoporous SnO₂ layers with 2.5 μm film thickness combined with a KuQuinone dye with a 3-carboxylpropyl-anchoring chain: these electrodes achieve light-harvesting efficiency of 93% at the maximum absorption wavelength of 533 nm, and photocurrent d. J up to 350 μA/cm² in the photoelectrochem. oxidation of ascorbate, although with a limited incident photon-to-current efficiency of 0.075%. Calculations based on the d. functional theory (DFT) support the role of the reduced species of the KuQuinone dye via a proton-coupled electron transfer as the competent species involved in the electron transfer to the tin oxide semiconductor. Finally, a preliminary investigation of the photoelectrodes towards benzyl alc. oxidation is presented, achieving photocurrent d. up to 90 μA/cm² in acetonitrile in the presence of N-hydroxysuccinimide and pyridine as redox mediator and base, resp. These results support the possibility of using mol.-based materials in synthetic photoelectrochem.

Application of C6H11BrO2, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., 4224-70-8.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 4224-70-8, formula is C6H11BrO2, The most pervasive is the naturally produced bromomethane. Recommanded Product: 6-Bromohexanoic acid

Walker, Rebecca;Majewska, Magdalena;Pociecha, Damian;Makal, Anna;Storey, John MD;Gorecka, Ewa;Imrie, Corrie T. research published 《 Twist-Bend Nematic Glasses: The Synthesis and Characterisation of Pyrene-based Nonsymmetric Dimers》, the research content is summarized as follows. A selection of pyrene-based liquid crystal dimers I [n = 5, 6, 8, etc.] , II [n = 5, 6, 11, etc.] and III were prepared, containing either methylene-ether or diether linked spacers of varying length and parity. All the diether linked materials, II, exhibited conventional nematic and smectic A phases, with the exception of II [n = 11] which was exclusively nematic. The methylene-ether linked dimer, I with an even-membered spacer (n=5) was solely nematogenic, but odd-members (n=6, 8, 10) exhibited both nematic and twist-bend nematic phases. Replacement of the cyanobiphenyl fragment by cyanoterphenyl giving III, gave elevated melting and nematic-isotropic transition temperatures, and SmA and SmC_A phases were observed on cooling the nematic phase. Intermol. face-to-face associations of the pyrene moieties drove glass formation, and all these materials had a glass transition temperature at or above room temperature The stability of the glassy twist-bend nematic phase allowed for its study using AFM, and the helical pitch length, P_TB, was measured as 6.3 and 6.7 nm for I [n = 6, 8] , resp. These values were comparable to the shortest pitch of a twist-bend nematic phase measured to date.

4224-70-8, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., Recommanded Product: 6-Bromohexanoic acid

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary