Related Products of 4117-09-3, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 4117-09-3 as follows.
General procedure: To 35.2 mL of 1,3-diaminopropane (422 mmol) at 0 C and under argon was added dropwise 5-bromopent-1-ene (5.0 mL, 42.2 mmol). The solution was stirred at 0 C one hour, and two additional hours at room temperature. The reaction mixture was then partitioned between AcOEt (250 mL), brine (40 mL), saturated aqueous NaHCO3 (40 mL), and H2O (40 mL). The aqueous layer was extracted with AcOEt and the combined organic extracts were dried over Na2SO4, filtered, and concentrated in vacuo. Purification by flash column chromatography on SiO2 with CHCl3/MeOH/NH4OH gradients afforded pure alkyl diamine 1 (5.64 g, 94%)
According to the analysis of related databases, 4117-09-3, the application of this compound in the production field has become more and more popular.
Reference:
Article; Decroos, Christophe; Bowman, Christine M.; Christianson, David W.; Bioorganic and Medicinal Chemistry; vol. 21; 15; (2013); p. 4530 – 4540;,
Bromide – Wikipedia,
bromide – Wiktionary