Category: 402-43-7

Borlinghaus, Niginia; Kaschel, Johannes; Klee, Johanna; Haller, Vanessa; Schetterl, Jasmin; Heitz, Stephanie; Lindner, Tanja; Dietrich, Justin D.; Braje, Wilfried M.; Jolit, Anais published their research in Journal of Organic Chemistry in 2021. The article was titled 《Reagent and Catalyst Capsules: A Chemical Delivery System for Reaction Screening and Parallel Synthesis》.Category: bromides-buliding-blocks The article contains the following contents:

Com. available hydroxypropyl methylcellulose capsules are employed as a fast, safe, and user-friendly chem. delivery system containing all reagents (catalyst, ligand, and base) for three important transition-metal-catalyzed reactions: Buchwald-Hartwig, Suzuki-Miyaura, and metallophotoredox C-N cross-coupling reactions. This encapsulation methodol. simplifies the screening of reaction conditions and the preparation of compound libraries using parallel synthesis in organic solvents or aqueous media. These reagents-containing HPMC capsules are easy to prepare, come in different sizes, and can be stored on the bench under noninert conditions. In addition to this study using 1-Bromo-4-(trifluoromethyl)benzene, there are many other studies that have used 1-Bromo-4-(trifluoromethyl)benzene(cas: 402-43-7Category: bromides-buliding-blocks) was used in this study.

1-Bromo-4-(trifluoromethyl)benzene(cas: 402-43-7) belongs to organobromine compounds.Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Dehydrobromination, Grignard reactions, reductive coupling, Wittig reaction, and several nucleophilic substitution reactions are some of the principal reactions which involve organic bromides. Category: bromides-buliding-blocks

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《The first used butylene linked bis(N-heterocyclic carbene)-palladium-PEPPSI complexes in the direct arylation of furan and pyrrole》 was published in Journal of Organometallic Chemistry in 2020. These research results belong to Kaloglu, Murat; Dusunceli, Serpil Demir; Ozdemir, Ismail. SDS of cas: 402-43-7 The article mentions the following:

The synthesis and characterization of butylene linked bis-benzimidazole based N-heterocyclic carbene (NHC) precursors I [R = 2-[bis(propan-2-yl)amino]ethyl, propan-2-yl, (pentamethylphenyl)methyl] and their PEPPSI-type bimetallic Pd-complexes II were reported, and its activities in the direct C5-arylation of 2-acetylfuran and 1-methylpyrrole-2-carboxaldehyde with various aryl bromides 4-R1C6H4Br (R1= H, MeO, Me, CHO, C(O)Me, CF3) and 3-bromoquinoline were implemented. The catalytic activities of the synthesized palladium-complexes II were found to be very high. The experimental process involved the reaction of 1-Bromo-4-(trifluoromethyl)benzene(cas: 402-43-7SDS of cas: 402-43-7)

1-Bromo-4-(trifluoromethyl)benzene(cas: 402-43-7) belongs to organobromine compounds.Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. SDS of cas: 402-43-7 Due to the reactivity of bromide, they are used as potential precursors or important intermediates in organic synthesis.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

The author of 《P-Chiral Phosphines Enabled by Palladium/Xiao-Phos-Catalyzed Asymmetric P-C Cross-Coupling of Secondary Phosphine Oxides and Aryl Bromides》 were Dai, Qiang; Li, Wenbo; Li, Zhiming; Zhang, Junliang. And the article was published in Journal of the American Chemical Society in 2019. Reference of 1-Bromo-4-(trifluoromethyl)benzene The author mentioned the following in the article:

The development of transition-metal-catalyzed methods for the synthesis of P-chiral phosphine derivatives poses a considerable challenge. Herein, the authors present a direct Pd/Xiao-Phos-catalyzed cross-coupling reaction of easily accessible secondary phosphine oxides and aryl bromides, which provides rapid access to P-chiral phosphine oxides. The reaction proceeds efficiently with a wide array of reaction partners to deliver various tertiary phosphine oxides in up to 96% yield and 97% ee. Also, the synthesis of DiPAMP ligand and its analogs was also realized, which demonstrates a suitable pathway to switching the branched chain of DiPAMP. The experimental process involved the reaction of 1-Bromo-4-(trifluoromethyl)benzene(cas: 402-43-7Reference of 1-Bromo-4-(trifluoromethyl)benzene)

1-Bromo-4-(trifluoromethyl)benzene(cas: 402-43-7) belongs to organobromine compounds.Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Reference of 1-Bromo-4-(trifluoromethyl)benzene Alkyl bromides are mainly used as alkylating agents and also find application as a solvent to extract oil from seeds and wool.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

The author of 《Energy Transfer to Ni-Amine Complexes in Dual Catalytic, Light-Driven C-N Cross-Coupling Reactions》 were Kudisch, Max; Lim, Chern-Hooi; Thordarson, Pall; Miyake, Garret M.. And the article was published in Journal of the American Chemical Society in 2019. Application of 402-43-7 The author mentioned the following in the article:

Dual catalytic light-driven cross-coupling methodologies utilizing a Ni(II) salt with a photocatalyst (PC) have emerged as promising methodologies to forge aryl C-N bonds under mild conditions. The recent discovery that the PC can be omitted and the Ni(II) complex directly photoexcited suggests that the PC may perform energy transfer (EnT) to the Ni(II) complex, a mechanistic possibility that has recently been proposed in other systems across dual Ni photocatalysis. Here, we report the first studies in this field capable of distinguishing EnT from electron transfer (ET), and the results are consistent with Förster-type EnT from the excited state [Ru(bpy)3]Cl2 PC to Ni-amine complexes. The structure and speciation of Ni-amine complexes that are the proposed EnT acceptors were elucidated by crystallog. and spectroscopic binding studies. With the acceptors known, quant. Förster theory was utilized to predict the ratio of quenching rate constants upon changing the PC, enabling selection of an organic phenoxazine PC that proved to be more effective in catalyzing C-N cross-coupling reactions with a diverse selection of amines and aryl halides. The results came from multiple reactions, including the reaction of 1-Bromo-4-(trifluoromethyl)benzene(cas: 402-43-7Application of 402-43-7)

1-Bromo-4-(trifluoromethyl)benzene(cas: 402-43-7) belongs to organobromine compounds.Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Due to the reactivity of bromide, they are used as potential precursors or important intermediates in organic synthesis. Application of 402-43-7

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

HPLC of Formula: 402-43-7In 2020 ,《Divergent and Stereoselective Synthesis of Tetraarylethylenes from Vinylboronates》 was published in Angewandte Chemie, International Edition. The article was written by Zhang, Minghao; Yao, Yisen; Stang, Peter J.; Zhao, Wanxiang. The article contains the following contents:

The synthesis of a new tetraborylethylene (TBE) is reported, and its application in the preparation of [4+0]-tetraarylethenes (TAEs) is elucidated. TAEs have widespread applications in material science and supramol. chem. due to their aggregation-induced emission (AIE) properties. The divergent and stereoselective synthesis of [3+1]-, [2+2]-, and [2+1+1]-TAEs via multiple couplings of vinylboronates with aryl bromides is demonstrated. These couplings feature a broad substrate scope and excellent functional group compatibility due to mild reaction conditions. Facile access to various tetraarylethenes is provided. This strategy represents an important complement to the conventional methods employed for the synthesis of TAEs, and would be a valuable tool for synthesizing TAE-based mols. useful in functional materials, biol. imaging and chem. sensing. In the experimental materials used by the author, we found 1-Bromo-4-(trifluoromethyl)benzene(cas: 402-43-7HPLC of Formula: 402-43-7)

1-Bromo-4-(trifluoromethyl)benzene(cas: 402-43-7) belongs to organobromine compounds.Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Dehydrobromination, Grignard reactions, reductive coupling, Wittig reaction, and several nucleophilic substitution reactions are some of the principal reactions which involve organic bromides. HPLC of Formula: 402-43-7

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

The author of 《Palladium-Catalyzed Construction of Quaternary Stereocenters by Enantioselective Arylation of γ-Lactams with Aryl Chlorides and Bromides》 were Jette, Carina I.; Geibel, Irina; Bachman, Shoshana; Hayashi, Masaki; Sakurai, Shunya; Shimizu, Hideki; Morgan, Jeremy B.; Stoltz, Brian M.. And the article was published in Angewandte Chemie, International Edition in 2019. Synthetic Route of C7H4BrF3 The author mentioned the following in the article:

The first Pd-catalyzed enantioselective arylation of α-substituted γ-lactams were reported. Two sets of conditions were developed for this transformation, allowing for the use of either aryl chlorides or bromides as electrophiles. Utilizing a highly electron-rich dialkylphosphine ligand, α-quaternary centers in good yields (up to 91% yield) and high enantioselectivities (up to 97% ee) was constructed.1-Bromo-4-(trifluoromethyl)benzene(cas: 402-43-7Synthetic Route of C7H4BrF3) was used in this study.

1-Bromo-4-(trifluoromethyl)benzene(cas: 402-43-7) belongs to organobromine compounds.Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Synthetic Route of C7H4BrF3 Dehydrobromination, Grignard reactions, reductive coupling, Wittig reaction, and several nucleophilic substitution reactions are some of the principal reactions which involve organic bromides.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Design of a Kilogram Scale, Plug Flow Photoreactor Enabled by High Power LEDs》 was published in Organic Process Research & Development in 2020. These research results belong to Levesque, Francois; Di Maso, Michael J.; Narsimhan, Karthik; Wismer, Michael K.; Naber, John R.. Quality Control of 1-Bromo-4-(trifluoromethyl)benzene The article mentions the following:

A simple and inexpensive photoreactor with a throughput of kilograms of material per day has been developed. This achievement was enabled by using high-power Light Emitting Diodes (LEDs) to provide high light d., leading to minimization of the footprint of the reactor. A study of the impact of tube diameter enabled maximization of the photon absorbance without increasing photocatalyst loading. Further optimization of reaction conditions using a design of experiments (DoE) elucidated reaction sensitivities that allowed the reaction rate, yield, and productivity to be maximized upon scale-up. The reactor has been operated continuously for 6 h leading to reaction performance that provided 12 kg of material per day at 90% conversion. The experimental process involved the reaction of 1-Bromo-4-(trifluoromethyl)benzene(cas: 402-43-7Quality Control of 1-Bromo-4-(trifluoromethyl)benzene)

1-Bromo-4-(trifluoromethyl)benzene(cas: 402-43-7) belongs to organobromine compounds.Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Quality Control of 1-Bromo-4-(trifluoromethyl)benzene Alkyl bromides are mainly used as alkylating agents and also find application as a solvent to extract oil from seeds and wool.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Formula: C7H4BrF3In 2021 ,《The Application of Pulse Radiolysis to the Study of Ni(I) Intermediates in Ni-Catalyzed Cross-Coupling Reactions》 appeared in Journal of the American Chemical Society. The author of the article were Till, Nicholas A.; Oh, Seokjoon; MacMillan, David W. C.; Bird, Matthew J.. The article conveys some information:

Here we report the use of pulse radiolysis and spectroelectrochem. to generate low-valent nickel intermediates relevant to synthetically important Ni-catalyzed cross-coupling reactions and interrogate their reactivities toward comproportionation and oxidative addition processes. Pulse radiolysis provided a direct means to generate singly reduced [(dtbbpy)NiBr], enabling the identification of a rapid Ni(0)/Ni(II) comproportionation process taking place under synthetically relevant electrolysis conditions. This approach also permitted the direct measurement of Ni(I) oxidative addition rates with electronically differentiated aryl iodide electrophiles (kOA = 1.3 x 104-2.4 x 105 M-1 s-1), an elementary organometallic step often proposed in nickel-catalyzed cross-coupling reactions. Together, these results hold implications for a number of Ni-catalyzed cross-coupling processes. In the experimental materials used by the author, we found 1-Bromo-4-(trifluoromethyl)benzene(cas: 402-43-7Formula: C7H4BrF3)

1-Bromo-4-(trifluoromethyl)benzene(cas: 402-43-7) belongs to organobromine compounds.Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Dehydrobromination, Grignard reactions, reductive coupling, Wittig reaction, and several nucleophilic substitution reactions are some of the principal reactions which involve organic bromides. Formula: C7H4BrF3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Photon Equivalents as a Parameter for Scaling Photoredox Reactions in Flow: Translation of Photocatalytic C-N Cross-Coupling from Lab Scale to Multikilogram Scale》 was written by Corcoran, Emily B.; McMullen, Jonathan P.; Levesque, Francois; Wismer, Michael K.; Naber, John R.. COA of Formula: C7H4BrF3 And the article was included in Angewandte Chemie, International Edition in 2020. The article conveys some information:

With the development of new photocatalytic methods over recent decades, the translation of these chem. reactions to industrial-production scales using continuous-flow reactors has become a topic of increasing interest. In this context, we describe our studies toward elucidating an empirically derived parameter for scaling photocatalytic reactions in flow. By evaluating the performance of a photocatalytic C-N cross-coupling reaction across multiple reactor sizes and geometries, it was demonstrated that expressing product yield as a function of the absorbed photon equivalent provides a predictive, empirical scaling parameter. Through the use of this scaling factor and characterization of the photonic flux within each reactor, the cross-coupling was scaled successfully from the milligram scale in batch to a multi-kilogram reaction in flow. After reading the article, we found that the author used 1-Bromo-4-(trifluoromethyl)benzene(cas: 402-43-7COA of Formula: C7H4BrF3)

1-Bromo-4-(trifluoromethyl)benzene(cas: 402-43-7) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. The most pervasive is the naturally produced bromomethane.COA of Formula: C7H4BrF3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

The author of 《Catalyst-Controlled 1,2- and 1,1-Arylboration of α-Alkyl Alkenyl Arenes》 were Bergmann, Allison M.; Dorn, Stanna K.; Smith, Kevin B.; Logan, Kaitlyn M.; Brown, M. Kevin. And the article was published in Angewandte Chemie, International Edition in 2019. Product Details of 402-43-7 The author mentioned the following in the article:

Two methods are reported for the 1,2- and 1,1-arylboration of α-Me vinyl arenes. In the case of 1,2-arylboration, the formation of a quaternary center occurred through a rare cross-coupling reaction of a tertiary organometallic complex. 1,1-Arylboration was enabled by catalyst optimization and occurred through a β-hydride elimination/reinsertion cascade. Enantioselective variants of both processes are presented as well as mechanistic investigations.1-Bromo-4-(trifluoromethyl)benzene(cas: 402-43-7Product Details of 402-43-7) was used in this study.

1-Bromo-4-(trifluoromethyl)benzene(cas: 402-43-7) belongs to organobromine compounds.The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. Product Details of 402-43-7 Dehydrobromination, Grignard reactions, reductive coupling, Wittig reaction, and several nucleophilic substitution reactions are some of the principal reactions which involve organic bromides.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary