Category: 3959-07-7

Ye, Zhi-Peng; Hu, Yuan-Zhuo; Guan, Jian-Ping; Chen, Kai; Liu, Fang; Gao, Jie; Xiao, Jun-An; Xiang, Hao-Yue; Chen, Xiao-Qing; Yang, Hua published the artcile< Photocatalytic Cyclization/Defluorination Domino Sequence to Access 3-Fluoro-1,5-dihydro-2H-pyrrol-2-one Scaffold>, Application In Synthesis of 3959-07-7, the main research area is fluoro dihydropyrrolone preparation photochem; allylbromodifluoroacetamide cyclic secondary amine tandem cyclization defluorination.

Herein an unprecedented photoinduced cyclization/defluorination domino process of N-allylbromodifluoroacetamide with cyclic secondary amines is reported. Consequently, a wide array of valuable 3-fluoro-1,5-dihydro-2H-pyrrol-2-ones I (R = Ph, 4-i-PrC6H4, Bn, etc.; X = O, N(Boc), N(COMe), etc.; R1 = H, Me) were facilely prepared from readily available starting materials under mild conditions. Preliminary mechanistic investigations suggest that a radical chain propagation and amine-promoted defluorination pathway are presumably involved in this transformation.

Organic Letters published new progress about Acetamides Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation) (N-allylbromodifluoro). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Application In Synthesis of 3959-07-7.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Kumar, Inder; Kumar, Rakesh; Gupta, Shiv Shankar; Sharma, Upendra published the artcile< C70 Fullerene Catalyzed Photoinduced Aerobic Oxidation of Benzylamines to Imines and Aldehydes>, Recommanded Product: 4-Bromobenzylamine, the main research area is C70 fullerene catalyzed photoinduced aerobic oxidation; benzylamine oxidation imine aldehyde preparation radical formation.

C70 fullerene catalyzed photoinduced oxidation of benzylic amines at ambient conditions has been explored here. The developed strategy’s main feature includes the additive/oxidant-free conversion of benzylic amine to corresponding imine and aldehydes. The reaction manifests broad substrate scope with excellent function group leniency and is applicable up to the gram scale. Further, sym. secondary amines can also be synthesized from benzylic amine in a one-pot two-step process. Various experiments and d. functional theory studies revealed that the current reaction involves the generation of reactive oxygen species, single electron transfer reaction, and benzyl radical formation as key steps under photocatalytic conditions.

Journal of Organic Chemistry published new progress about Aldehydes Role: SPN (Synthetic Preparation), PREP (Preparation). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Recommanded Product: 4-Bromobenzylamine.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Cai, Rongbin; Zhou, Qi; Hou, Tianjiao; Li, Bing; Liu, Yunzhi; Li, Huan; Gao, Yuan; Zhu, Longyi; Luo, Jun published the artcile< Facile construction of the all-bridge-position-functionalized 2,4,6,8-tetraazaadamantane skeleton and conversion of its N-functionalities>, Safety of 4-Bromobenzylamine, the main research area is tetraazaadamantanyl tricyclic preparation.

In this article, an unusual protocol of a “”one-pot”” three-step strategy to build the special all-bridge-position-functionalized tetraazaadamantane skeletons I [R = i-Bu, Bn, CH2-2-furyl, etc.] from 2,2-dipropenyl-1,3-dioxolane via ozonation, hydrogenation with 5% Pd/BaSO4, and condensation of the in-situ generated dial intermediate with primary amines was reported for the first time. Different primary amines were compatible with this process and the corresponding 2,4,6,8-tetraalkyl-2,4,6,8-tetraazaadamantane-9,10-dione bis(ethylene ketals) were achieved in 19-46% yields. The conversion of the N-benzyl group to some other functionalities such as acetyl, benzoyl, nitroso and nitro was also investigated.

Organic Chemistry Frontiers published new progress about Condensation reaction. 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Safety of 4-Bromobenzylamine.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Banerji, Biswadip; Adhikary, Saswati; Majumder, Leena; Ghosh, Saswati published the artcile< A Green Synthetic Approach towards Polyarylated Oxazoles via Iodine-Catalyzed One-Pot sp3 C-H Functionalization in Water: From Natural Product Synthesis To Photophysical Studies>, Safety of 4-Bromobenzylamine, the main research area is polyaryl oxazole preparation green chem regioselective; primary amine diketone acyloin aerobic oxidative cyclization iodine catalyst.

A ‘green’ methodol. for the convenient synthesis of specific regioisomers of polysubstituted oxazoles through iodine catalyzed, water-mediated, aerobic oxidative C(sp3)-H functionalization of primary amines has been developed. This mild and regioselective domino procedure does not require toxic peroxides, transition metals and organic solvents. The versatility of this methodol. was demonstrated by preparing a natural product, texaline. It is also scalable and has a wide substrate scope. This methodol. opens up a simple avenue for the synthesis of polyarylated oxazoles from various readily available amines as well as 1,2-diketones and acyloins (α-hydroxyl ketones) in moderate to excellent yields. Furthermore, these highly substituted oxazole mols. showed excellent fluorescence properties and thus have enormous potential to be a new type of fluorescent probe for use in medicinal applications and materials science.

Asian Journal of Organic Chemistry published new progress about Diketones, 1,2-diketones Role: RCT (Reactant), RACT (Reactant or Reagent). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Safety of 4-Bromobenzylamine.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Wang, Wenxing; Zhang, Shuo; Shi, Guang; Chen, Zhiwei published the artcile< Electrochemical synthesis of 1,2,4,5-tetrasubstituted imidazoles from enamines and benzylamines>, Related Products of 3959-07-7, the main research area is imidazole preparation green chem; enamine benzylamine electrochem amination.

An electrochem. method for synthesizing 1,2,4,5-tetrasubstituted imidazoles I (R = Me, Et, Ph, i-Pr; R1 = n-Bu, Bn, cyclohexyl, 4-chlorophenyl, naphthalen-1-yl, etc.; R2 = Me, OMe, OEt, Ot-Bu; R3 = Ph, 2,3-dichlorophenyl, thiophen-2-yl, etc.) was developed under undivided electrolytic conditions. This synthesis was specifically realized based on electrochem. C(sp3)-H amination via enamines (Z)-RC(NHR1)=C(O)R2 and amines R3NH2. Readily available starting materials were used, avoiding the use of both transition metals and oxidants. The practicability of the method lies in its broad substrate adaptability and in its ability to provide a simple green pathway for synthesizing GABAA receptor analogs I (R = Me; R1 = 2,4-dichlorophenyl; R2 = OEt; R3 = 4-bromophenyl).

Organic & Biomolecular Chemistry published new progress about Amination. 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Related Products of 3959-07-7.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Li, Xia; Xu, Hui; Shi, Ji-Long; Hao, Huimin; Yuan, Hong; Lang, Xianjun published the artcile< Salicylic acid complexed with TiO2 for visible light-driven selective oxidation of amines into imines with air>, Recommanded Product: 4-Bromobenzylamine, the main research area is salicylic acid complexed anatase visible light selective oxidation amines; selective oxidation amine imines air.

The interplay of salicylic acid (SA) and reactive oxygen species (ROS) can modulate biotic and abiotic stress of plants, essential biol. aerobic oxidation processes. Meanwhile, ROS plays a critical role in TiO2 photocatalytic system for the degradation of organic species. Herein, we developed a system consisted of SA and TiO2 aiming at the selective oxidation of organic mols. by ROS. Interestingly, SA complexed with TiO2 leads to ligand-to-metal charge transfer (LMCT) under visible light irradiation The charge transfer from ligand (chem. adsorbed SA) to metal (conduction band of TiO2) activates O2 to ROS, superoxide (O·-2). The pos. charge located at ligand SA is connected with (2,2,6,6-tetramethylpiperidin-1-yl)oxyl (TEMPO) catalysis for direct two-electron oxidation of amines and later regenerated by O·2-. SA and its derivatives were screened as ligands of TiO2 for the selective aerobic oxidation of amines into imines under blue light-emitting diode (LED) irradiation in which 5-CH3O-SA (5-methoxysalicylic acid, 0.8 mol%) complexed with anatase TiO2 and coupled with TEMPO (5 mol%) confers significantly better results than the others. By this visible light LMCT route, both primary amines and secondary amines can be selectively oxidized into corresponding imines with atm. O2 as the terminal oxidant. Importantly, the desired product of N-benzylidenebenzylamine can be isolated in 92% yield.

Applied Catalysis, B: Environmental published new progress about Amines Role: PEP (Physical, Engineering or Chemical Process), RCT (Reactant), PROC (Process), RACT (Reactant or Reagent). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Recommanded Product: 4-Bromobenzylamine.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Schmitt, Tanja; Bourelle, Sean; Tye, Nathaniel; Soavi, Giancarlo; Bond, Andrew D.; Feldmann, Sascha; Traore, Boubacar; Katan, Claudine; Even, Jacky; Dutton, Sian E.; Deschler, Felix published the artcile< Control of Crystal Symmetry Breaking with Halogen-Substituted Benzylammonium in Layered Hybrid Metal-Halide Perovskites>, Name: 4-Bromobenzylamine, the main research area is crystal symmetry breaking halobenzylammonium lead iodide layered hybrid perovskite.

Layered hybrid metal-halide perovskites with noncentrosym. crystal structure are predicted to show spin-selective band splitting from Rashba effects. Thus, fabrication of metal-halide perovskites with defined crystal symmetry is desired to control the spin-splitting in their electronic states. Here, the authors report the influence of halogen para-substituents on the crystal structure of benzylammonium lead iodide perovskites (4-XC6H4CH2NH3)2PbI4 (X = H, F, Cl, Br). Using x-ray diffraction and 2nd-harmonic generation, the authors study structure and symmetry of single-crystal and thin-film samples. The authors report that introduction of a halogen atom lowers the crystal symmetry such that the Cl- and Br-substituted structures are noncentrosym. The differences can be attributed to the nature of the intermol. interactions between the organic mols. The authors calculate electronic band structures and find good control of Rashba splittings. The results present a facile approach to tailor hybrid layered metal halide perovskites with potential for spintronic and nonlinear optical applications.

Journal of the American Chemical Society published new progress about Band structure. 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Name: 4-Bromobenzylamine.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Miguel-Casan, Eugenia; Andres-Garcia, Eduardo; Calbo, Joaquin; Gimenez-Marques, Monica; Minguez Espallargas, Guillermo published the artcile< Selective CO2 Sorption Using Compartmentalized Coordination Polymers with Discrete Voids**>, Quality Control of 3959-07-7, the main research area is coordination polymer void carbon dioxide sorption; CO2; gas separation; metal-organic frameworks; voids.

Carbon capture and storage with porous materials is one of the most promising technologies to minimize CO2 release into the atm. Here, we report a family of compartmentalized coordination polymers (CCPs) capable of capturing gas mols. in a selective manner based on two novel tetrazole-based ligands. Crystal structures have been modelled theor. under the D. Functional Theory (DFT) revealing the presence of discrete voids of 380 Å3. Single gas adsorption isotherms of N2, CH4 and CO2 have been measured, obtaining a loading capacity of 0.6, 1.7 and 2.2 mols./void at 10 bar and at 298 K for the best performing material. Moreover, they present excellent selectivity and regenerability for CO2 in mixtures with CH4 and N2 in comparison with other reported materials, as evidenced by dynamic breakthrough gas experiments These frameworks are therefore great candidates for separation of gas mixtures in the chem. engineering industry.

Chemistry – A European Journal published new progress about Adsorption enthalpy, isosteric. 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Quality Control of 3959-07-7.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Zou, Wen; Liu, Xiao-Hui; Xue, Can; Zhou, Xian-Tai; Yu, Hai-Yang; Fan, Ping; Ji, Hong-Bing published the artcile< Enhancement of the visible-light absorption and charge mobility in a zinc porphyrin polymer/g-C3N4 heterojunction for promoting the oxidative coupling of amines>, Category: bromides-buliding-blocks, the main research area is zinc porphyrin microporous polymer photooxidation photocatalysis heterojunction.

Graphitic carbon nitride (g C3N4, CN) has been widely used as a photocatalyst due to its high stability and suitable band gap. However, its further development is limited due to inefficient light harvesting and rapid recombination of photogenerated carriers. In this study, a visible-light-responsive zinc porphyrin (ZnP)/CN heterojunction photocatalyst was synthesized by the combination of CN and a zinc-porphyrin-conjugated microporous polymer (ZnP-CMP). ZnP/CN exhibited excellent photocatalytic activity for the oxidative coupling of amines to imines under visible-light irradiation The efficiency of the as-developed photocatalyst was 25 times greater than that of CN and about 2 times greater than that of ZnP-CMP. The significantly enhanced catalytic efficiency was attributed to the promotion of visible-light harvesting and photogenerated charge mobility via the introduction of ZnP-CMP. The ZnP/CN heterojunction photocatalyst also exhibited excellent broad substrate scope, stability, and reusability.

Applied Catalysis, B: Environmental published new progress about Crystal vacancies (oxygen). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Category: bromides-buliding-blocks.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Ke, Da; Zhou, Shaodong published the artcile< General Construction of Amine via Reduction of N=X (X = C, O, H) Bonds Mediated by Supported Nickel Boride Nanoclusters>, Quality Control of 3959-07-7, the main research area is primary amine preparation; nitrile reduction nickel boride nanocluster catalyst; nitro compound hydrogenation nickel boride nanocluster catalyst; benzaldehyde reduction nickel boride nanocluster catalyst; hydrogenation; nickel boride; primary amine; reductive amination.

Herein, an efficient catalyst for the general construction of amine mediated by nickel boride nanoclusters supported by a TS-1 mol. sieve was reported. Efficient production of amines RCH2NH2 (R = 5-aminopentyl, cyclohexyl, Ph, pyridin-2-yl, etc.), 3-R1-4-R2-C6H3NH2 (R1 = H, F; R2 = H, F, Cl, Me, Br, OH, NH2) was achieved via catalytic hydrogenation of N=X (X = C, O, H) bonds. In addition, the catalyst maintains excellent performance upon recycling. Compared with the previous reports, the high activity, simple preparation and reusability of the Ni-B catalyst in this work make it promising for industrial application in the production of amines.

International Journal of Molecular Sciences published new progress about Benzaldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Quality Control of 3959-07-7.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary