Category: 3959-07-07 00:00:00

Wu, Shujuan; Zhang, Yu-Fei; Ding, Huimin; Li, Xia; Lang, Xianjun published the artcile< Hydrazone-linked 2D porphyrinic covalent organic framework photocatalysis for visible light-driven aerobic oxidation of amines to imines>, Category: bromides-buliding-blocks, the main research area is hydrazone linked porphyrinic covalent organic framework catayst preparation; imine preparation; amine aerobic oxidation photocatalyst; Aerobic oxidation; Covalent organic frameworks; Hydrazone linkage; Imines; Visible light.

A hydrazone-linked 2D (two-dimensional) porphyrinic COF, Por-DETH-COF, was assembled from 5,10,15,20-tetrakis(4-benzaldehyde)porphyrin (p-Por-CHO) and 2,5-diethoxyterephthalohydrazide (DETH) and its photocatalytic activity was duly appraised with the aerobic oxidation of amines. Thereby, the red light-driven selective oxidation of benzyl amines to imines RCH=NR1 [R = Ph, 4-FC6H4, 2-thienyl, etc.; R1 = t-Bu, Bn, 4-MeC6H4CH2, etc.]was obtained in very high conversions and selectivities with ambient air as the oxidant. Importantly, the photocatalytic system exhibited remarkable compatibility of functional groups and extensive scope of benzyl amines. Notably, the Por-DETH-COF photocatalyst displayed outstanding recyclability after five successive cycles. This work suggests that 2D COFs could contribute a unique juncture for selective organic transformations by photocatalysis.

Journal of Colloid and Interface Science published new progress about Covalent organic frameworks. 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Category: bromides-buliding-blocks.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Fan, Qiangwen; Zhu, Longwei; Li, Xuhuai; Ren, Huijun; Zhu, Haibo; Wu, Guorong; Ding, Jianhua published the artcile< Visible-light photocatalytic selective oxidation of amine and sulfide with CsPbBr3 as photocatalyst>, Formula: C7H8BrN, the main research area is imine aldehyde sulfoxide preparation; amine sulfide photocatalytic oxidation cesium lead bromide.

Using a readily accessible and high-efficiency photocatalyst for inducing chem. transformations is highly desirable. All inorganic lead halide perovskites (APbX3, X = Cl, Br, I) are utilized intensively in photovoltaics providing outstanding optoelectronic performance and are easy-to-process, but their use in organic synthesis is still in its infancy. Herein, a facile protocol for the photocatalytic oxidation of a series of amines and sulfides to their corresponding imines and sulfoxides with excellent yields and selectivity using CsPbBr3 as a visible-light catalyst is reported. The result show that amines bearing electron-donating groups give rise to aldehydes as the final products, while amines with electron-withdrawing groups afford imines as the major products. Reaction mechanism studies reveal that the photogenerated holes (h+), superoxide radicals (O2 ̇-) and singlet oxygen are involved in the reaction performed in air and O2 atmospheres. In addition, for the reaction conducted under anaerobic conditions, free radicals generated by amines plays a vital role in determining the transformation of amines to imines.

New Journal of Chemistry published new progress about Aralkyl amines Role: RCT (Reactant), RACT (Reactant or Reagent). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Formula: C7H8BrN.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Yang, Xue; Huang, Tao; Gao, Shuiying; Cao, Rong published the artcile< Boosting photocatalytic oxidative coupling of amines by a Ru-complex-sensitized metal-organic framework>, Category: bromides-buliding-blocks, the main research area is oxidative coupling photocatalyst metal organic framework.

Visible-light-driven selective photocatalytic organic synthesis has recently become a topic of great interest due to its environmental friendliness and sustainability. It is demanding for photocatalysis to utilize the wider range of light, such as visible light, and its performance is often plagued by the sluggish separation of photogenerated charge carriers. An approach is now reported to address these issues by incorporating light harvesting RuII-polypyridyl complexes into a semiconductor-type metal-organic framework (MIL-125). Delightedly, the obtained Ru(bpy)3@MIL-125 photocatalyst presents a remarkably stable and high photoactivity toward the selective oxidative coupling of amines under ambient air with visible light irradiation (λ > 440 nm). The mechanistic investigation unveiled that both effectively photoexcited electrons transfer from [Ru(bpy)3]Cl2 to MIL-125 and the interaction of C-H bonds with superoxide radical (O·-2) play a critical role in photo-catalyzing selective aerobic oxidative coupling of amines. This work highlights a significant role of MOFs as heterogeneous photocatalysts in photocatalytic organic transformations.

Journal of Catalysis published new progress about Electric capacitance. 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Category: bromides-buliding-blocks.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Li, Peiyu; Dong, Xiaoyun; Zhang, Ya; Lang, Xianjun; Wang, Cheng published the artcile< An azine-linked 2D porphyrinic covalent organic framework for red light photocatalytic oxidative coupling of amines>, Related Products of 3959-07-7, the main research area is azine porphyrinic covalent organic framework benzylamine photocatalytic oxidative coupling.

The construction of two-dimensional covalent organic frameworks (2D COFs) with robust stability for photocatalysis has gained intensive attention recently. Herein, we report the design and synthesis of a highly crystalline azine-linked porphyrinic 2D COF (Por-HZ-COF). Our results clearly show that Por-HZ-COF adopts an eclipsed AA stacking structure with a high Brunauer-Emmett-Teller (BET) sp. surface area of 1586 m2/g. In addition, Por-HZ-COF is chem. stable under various conditions, even in 12 M sodium hydroxide aqueous solution or 9 M hydrochloric acid. Moreover, Por-HZ-COF can be used for the photocatalytic aerobic oxidative coupling of benzylamines under red light irradiation with high activity and good reusability. This study demonstrates a novel robust 2D COF with azine linkage that has promising applications in photocatalysis.

Materials Today Chemistry published new progress about Anaerobic oxidation. 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Related Products of 3959-07-7.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Adhikary, Saswati; Majumder, Leena; Pakrashy, Sourav; Srinath, Ravuri; Mukherjee, Kaustuv; Mandal, Chitra; Banerji, Biswadip published the artcile< Polysubstituted Imidazoles as LysoTracker Molecules: Their Synthesis via Iodine/H2O and Cell-Imaging Studies>, Name: 4-Bromobenzylamine, the main research area is imidazole regioselective synthesis fluorescent lysosome staining probe.

An iodine-catalyzed, environmentally benign one-pot methodol. has been developed for the synthesis of diverse substituted imidazoles. This transition-metal-free, aerobic, water-mediated cyclization reaction is operationally simple and works well with different amines or aldehydes by multiple C-N bond formations with satisfactory yield. The methodol. is regioselective as well as scalable. These imidazole derivatives show excellent fluorescence properties both in the solid and solution phase, which is further extended to live-cell imaging. Due to the suitable fluorescence properties of these scaffolds, lysosome-directing groups are incorporated in two of these derivatized imidazoles to track intracellular lysosomes. Successfully, those mols. show bright blue fluorescence while detecting lysosomes in human or murine cells and can be considered to be rapid lysosome-staining probes.

ACS Omega published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Name: 4-Bromobenzylamine.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Jiang, Wen-Nian; Zhao, Qing-Lan; Cheng, Wen-Shuo; Xiao, Jun-An; Xiang, Hao-Yue; Chen, Kai; Yang, Hua published the artcile< CuI-mediated benzannulation of (ortho-arylethynyl)phenylenaminones to assemble α-aminonaphthalene derivatives>, Recommanded Product: 4-Bromobenzylamine, the main research area is aminonaphthalene preparation; arylethynyl phenylenaminone amine preparation benzannulation copper iodide catalyst.

Simple manipulation of exogenous amines readily offers the structural diversity of the resulting α-aminonaphthalenes II. Preliminary investigation of the photophys. features of the representative as-prepared compounds demonstrated their tunable fluorescence properties. A copper-mediated annulation protocol for new (ortho-arylethynyl)phenyl enaminones I (R = dimethylaminyl, pyrrolidin-1-yl, cyclohexylaminyl, etc.; R1 = H, 4-(C(O)2CH3)C6H4, 4-NCC6H4; R2 = C6H5, 4-(CH2CH3)C6H4, 4-((CH2)2CH3)C6H4, 4-((CH2)3CH3)C6H4, 4-CH3OC6H4, 4-FC6H4) bearing a N,N-dimethylamine moiety was developed to facilely install a series of α-aminonaphthalene derivatives II.

Organic Chemistry Frontiers published new progress about Amines Role: RCT (Reactant), RACT (Reactant or Reagent). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Recommanded Product: 4-Bromobenzylamine.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Chen, Peng; Meng, Ling-Hu; Chen, Lang; Guo, Jun-Kang; Shen, Sheng; Au, Chak-Tong; Yin, Shuang-Feng published the artcile< Double-Shell and Flower-Like ZnS-C3N4 Derived from in Situ Supramolecular Self-Assembly for Selective Aerobic Oxidation of Amines to Imines>, Electric Literature of 3959-07-7, the main research area is Double Shell nanoflower zinc sulfide carbon nitride photocatalyst; photooxidation amines imines.

Multishelled micro-/nanostructures have attracted much research attention because of their unique properties. It is a big challenge to fabricate multishelled hollow structures of complex nanoarchitectures with the resp. shells different in composition Herein, the double-shell and flower-like ZnS-C3N4 (2-ZSCN) was fabricated by a facile supramol. self-assembly method. Because of its unique structure, 2-ZSCN exhibits enhanced photocatalytic activity and stability in the selective aerobic oxidation of amines to imines under visible-light irradiation

ACS Sustainable Chemistry & Engineering published new progress about Aralkyl amines Role: PEP (Physical, Engineering or Chemical Process), RCT (Reactant), PROC (Process), RACT (Reactant or Reagent). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Electric Literature of 3959-07-7.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Wilson, Katy B.; Nedzbala, Hannah S.; Simpson, Spenser R.; Ericson, Megan N.; Westendorff, Karl S.; Chordia, Mahendra D.; Dickie, Diane A.; Harman, W. Dean published the artcile< Hydroamination of Dihapto-Coordinated Benzene and Diene Complexes of Tungsten: Fundamental Studies and the Synthesis of γ-Lycorane>, Recommanded Product: 4-Bromobenzylamine, the main research area is hydroamination dihapto benzene diene tungsten complex; gamma lycorane preparation; crystal mol structure dihapto alkene tungsten complex; arenes; cyclohexenes; dearomatization; dienes; hydroamination; lycorane; nitrosyl ligands; tungsten.

Reactions are described for complexes of the form WTp(NO)(PMe3)(η2-arene) and various amines, where the arene is benzene or benzene with an electron-withdrawing substituent (CF3, SO2Ph, SO2Me). The arene complex is first protonated to form an η2-arenium species, which then selectively adds the amine. The resulting η2-5-amino-1,3-cyclohexadiene complexes can then be subjected to the same sequence with a second nucleophile to form 3-aminocyclohexene complexes, where up to three stereocenters originate from the arene carbons. Alternatively, 1,3-cyclohexadiene complexes containing an ester group at the 5 position (also prepared from an arene) can be treated with acid followed by an amine to form trisubstituted 3-aminocyclohexenes. When the amine is primary, ring closure can occur to form a cis-fused bicyclic γ-lactam. Highly functionalized cyclohexenes can be liberated from the tungsten through oxidative decomplexation. The potential utility of this methodol. is demonstrated in the synthesis of the alkaloid γ-lycorane. An enantioenriched synthesis of a lactam precursor to γ-lycorane is also described. This compound is prepared from an enantioenriched version of the tungsten benzene complex. Regio- and stereochem. assignments for the reported compounds are supported by detailed 2D-NMR anal. and 13 mol. structure determinations (SC-XRD).

Helvetica Chimica Acta published new progress about Crystal structure. 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Recommanded Product: 4-Bromobenzylamine.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Chen, Wei-Li; Li, Kun; Liao, Wei-Cong; Liang, Wang-Fu; Qiu, Pei-Wen; Liang, Cui; Su, Gui-Fa; Mo, Dong-Liang published the artcile< An iron(III)-catalyzed dehydrogenative cross-coupling reaction of indoles with benzylamines to prepare 3-aminoindole derivatives>, Category: bromides-buliding-blocks, the main research area is amino indole derivative green preparation diastereoselective; indole benzylamine dehydrogenative cross coupling iron catalyst.

A green cascade approach to prepare a variety of 3-aminoindole derivatives I [R1 = H, 7-Me, 6-Cl, etc.; R2 = H, Me; R3 = Ph, 3-BrC6H4, 2-naphthyl, etc.; R4 = Ph, 2-FC6H4, 3-pyridyl, etc.; R5 = H, Et, Ph] in good to excellent yields through an iron(III)-catalyzed dehydrogenative cross-coupling reaction of 2-arylindoles and primary benzylamines under mild reaction conditions was reported. The reaction showed a broad substrate scope of indoles and benzylamines and tolerated a wide range of functional groups. Moreover, the reaction was easily performed at the gram scale without producing waste after the reaction was completed. The present method highlighted readily available starting materials, a simple purification procedure and the usage of cheap, nontoxic and environmentally benign iron(III) catalyst.

Green Chemistry published new progress about Aromatic amines Role: PRP (Properties), RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Category: bromides-buliding-blocks.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Canh Pham, Em; Truong, Tuyen Ngoc published the artcile< Design, Microwave-Assisted Synthesis, Antimicrobial and Anticancer Evaluation, and In Silico Studies of Some 2-Naphthamide Derivatives as DHFR and VEGFR-2 Inhibitors>, SDS of cas: 3959-07-7, the main research area is naphthamide preparation microwave antibacterial antifungal anticancer DHFR VEGFR inhibitor.

Naphthamide is a common structural framework with diverse pharmacol. activities. Ten novel 2-naphthamide derivatives I (R = 3-(morpholin-4-yl)propyl, (4-methylphenyl)methyl, (4-methoxyphenyl)methyl, (4-bromophenyl)methyl, (4-chlorophenyl)methyl; R1 = H, OMe; R2 = H, OMe; R3 = H, OMe; R4 = H, OMe) have been designed, synthesized, and evaluated for their in vitro antibacterial, antifungal, and anticancer activities. The title compounds were synthesized from dimethoxybenzaldehyde derivatives such as 2,4-dimethoxybenzaldehyde and 3,5-dimethoxybenzaldehyde through a four-step microwave-assisted synthesis process. The structures were confirmed by 1H NMR, 13C NMR, and MS spectra. Compound I [R = (4-chlorophenyl)methyl ; R1 = R3 = H; R2 = R4 = OMe] (II) showed good antibacterial activity against Escherichia coli, Streptococcus faecalis, Salmonella enterica, MSSA, and MRSA with MIC values of 16, 16, 16, 8, and 16 μg/mL, resp., compared to ciprofloxacin (MIC = 8-16 μg/mL). Compounds I (R = (4-methylphenyl)methyl ; R1 = R3 = H; R2 = R4 = OMe)(III) (IC50 = 3.59-8.38 μM) and II (IC50 = 2.97-7.12 μM) exhibited good cytotoxic activity against C26, HepG2, and MCF7 cancer cell lines as compared to paclitaxel (IC50 = 2.85-5.75 μM). Moreover, compounds II and III exhibited better anticancer activity than PTX against the C26 cell line. In particular, compound II showed potent in vitro VEGFR-2 inhibitory activity with the IC50 value of 0.384 μM compared with sorafenib (IC50 = 0.069 μM). Therefore, compound II is the most potent compound for anticancer activity as indicated by in vitro cell line inhibition, in silico ADMET, mol. docking, and in vitro VEGFR-2 inhibition studies.

ACS Omega published new progress about Absorption. 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, SDS of cas: 3959-07-7.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary