Category: 3959-07-07 00:00:00

Yadav, Suman; Reshi, Noor U. Din; Pal, Saikat; Bera, Jitendra K. published the artcile< Aerobic oxidation of primary amines to amides catalyzed by an annulated mesoionic carbene (MIC) stabilized Ru complex>, Safety of 4-Bromobenzylamine, the main research area is primary amine ruthenium catalyst aerobic oxidation; amide preparation.

Catalytic aerobic oxidation of primary amines to the amides, using the precatalyst [Ru(COD)(L1)Br2] bearing an annulated π-conjugated imidazo[1,2-a][1,8]naphthyridine-based mesoionic carbene ligand L1, was disclosed. This catalytic protocol was distinguished by its high activity and selectivity, wide substrate scope and modest reaction conditions. A variety of primary amines, RCH2NH2 (R = aliphatic, aromatic and heteroaromatic), were converted to the corresponding amides using ambient air as an oxidant in the presence of a sub-stoichiometric amount of KOtBu in tBuOH. A set of control experiments, Hammett relationships, kinetic studies and DFT calculations were undertaken to divulge mechanistic details of the amine oxidation using [Ru(COD)(L1)Br2]. The catalytic reaction involveed abstraction of two amine protons and two benzylic hydrogen atoms of the metal-bound primary amine by the oxo and hydroxo ligands, resp. A β-hydride transfer step for the benzylic C-H bond cleavage was not supported by Hammett studies. The nitrile generated by the catalytic oxidation undergoes hydration to afford the amide as the final product.

Catalysis Science & Technology published new progress about Activation enthalpy. 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Safety of 4-Bromobenzylamine.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Ma, Zhiming; Liu, Shiqiang; Tang, Nanfang; Song, Tao; Motokura, Ken; Shen, Zhemin; Yang, Yong published the artcile< Coexistence of Fe Nanoclusters Boosting Fe Single Atoms to Generate Singlet Oxygen for Efficient Aerobic Oxidation of Primary Amines to Imines>, Safety of 4-Bromobenzylamine, the main research area is iron nanocluster porous carbon doped catalyst preparation surface area; amine iron nanocluster catalyst oxidation imine preparation.

Tuning the geometric and electronic structure of the single-metal-atom catalysts via simultaneous presence of metal nanoparticles or nanoclusters (NCs) offers an alternative avenue to improving their catalytic performance. Herein, that the coexistence of Fe NCs in proximity to Fe single atoms on N-doped porous carbon can significantly improve the catalytic performance in aerobic oxidation of primary amines to imines using air as the oxidant was demonstrate. A broad spectrum of primary aromatic, heterocyclic, and aliphatic amines was efficiently and selectively oxidized into their corresponding imines in good to high yields. Exptl. measurements and theor. calculations reveal that the proximity of Fe NCs interacts with Fe single atoms, which not only benefits the adsorption of mol. O2 and amine substrates but also promotes the activation of O2 to selectively generate singlet oxygen (1O2) and then facilitates the key intermediate imine formation via H-atom abstraction with a lower energy barrier, thereby significantly boosting the reaction activity.

ACS Catalysis published new progress about Adsorption. 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Safety of 4-Bromobenzylamine.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Gao, Haijing; Chen, Yajie; Li, Huali; Zhang, Fangfang; Tian, Guohui published the artcile< Hierarchical Cu7S4-Cu9S8 heterostructure hollow cubes for photothermal aerobic oxidation of amines>, Reference of 3959-07-7, the main research area is photocatalysis aerobic photooxidation photothermal effect nanosheet hollow nanocube.

Copper-based chalcogenides have been paid intensive attention as alternate photothermal catalysts for solar energy conversion. Despite considerable progress of copper sulfides nanostructure fabrication, combining independent copper sulfides polymorphs with various stoichiometries by forming heterojunction is still challenging. Herein, unique hierarchical nanosheet-assembled Cu7S4-Cu9S8 heterostructure hollow cubes with remarkable photothermal aerobic oxidation activity were prepared by a facile one-pot chem. transformation route using Cu2O cubes as sacrificial template for the first time. In this reaction system, the introduction of proper sulfur source thioacetamide and moderate alk. conditions plays a crucial role in phase transformation, and through tunning the reaction time, a series of Cu7S4, Cu7S4-Cu9S8, and Cu9S8 can be selectively prepared Furthermore, the Cu7S4-Cu9S8 polymorphic heterostructure hollow cubes exhibit significantly enhanced photothermal aerobic oxidation performance of amines to the corresponding imines compared with the individual Cu7S4 and Cu9S8 in both N, N-dimethylformamide and acetonitrile solvent medium. Our results indicated that the strong near-IR plasmonic absorption of Cu7S4-Cu9S8 facilitated hot carrier transport between Cu7S4 and Cu9S8, which subsequently promoted the catalytic reactions. Especially after uniform load of Au-Pt alloy nanoparticles, the photothermal aerobic oxidation activity was further enhanced due to their boosted synergistic local coupling enhancement effect between distinct components in the N, N-dimethylformamide solvent medium. Such enhanced photothermal reaction could effectively promote sunlight utilization in a wide range of photocatalytic reactions.

Chemical Engineering Journal (Amsterdam, Netherlands) published new progress about Aralkyl amines Role: RCT (Reactant), RACT (Reactant or Reagent). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Reference of 3959-07-7.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Heard, David M.; Doobary, Sayad; Lennox, Alastair J. J. published the artcile< 3D Printed Reactionware for Synthetic Electrochemistry with Hydrogen Fluoride Reagents>, COA of Formula: C7H8BrN, the main research area is three dimensional printing electrochem hydrogen fluoride reagent.

Electrochem. fluorination reactions of organic compounds frequently employ hydrogen fluoride reagents that are corrosive. The corrosive nature of these reagents necessitates either the construction or purchase of cells that are stable to hydrogen fluoride, which require high-cost materials, machining time and expertise. Herein, we offer an alternative solution using 3D printing, which is an inexpensive and rapid manufacturing technique. We have designed, printed and shared four different cell types in polypropylene and tested them in an electrochem. alkene difluorination reaction in the presence of triethylamine. 3HF and pyridinium poly. (HF).

ChemElectroChem published new progress about Electrochemical fluorination. 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, COA of Formula: C7H8BrN.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Kumar, Anurag; Sadanandhan, Aathira M.; Jain, Suman L. published the artcile< Silver doped reduced graphene oxide as a promising plasmonic photocatalyst for oxidative coupling of benzylamines under visible light irradiation>, Electric Literature of 3959-07-7, the main research area is silver reduced graphene oxide nanocomposite photocatalyst amine imine.

Visible light assisted photocatalytic transformations have been considered as an efficient and sustainable approach for the production of high-value chems. The present paper describes the synthesis of plasmonic silver nanoparticle incorporated reduced graphene oxide and its photocatalytic performance for the selective oxidation of various benzylamines to the corresponding imines using mol. oxygen as an oxidant under ambient temperature conditions. The developed photocatalyst was found to be highly stable and exhibited excellent photoactivity with a consistent recycling ability for several runs without a loss in activity. Moreover, to the best of our knowledge, the developed photocatalyst represents the first example of a graphene-based photocatalyst for the oxidative coupling of amines.

New Journal of Chemistry published new progress about IR spectra. 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Electric Literature of 3959-07-7.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Liu, Gang; Liu, Sen; Li, Zhen; Chen, Hengyu; Li, Jiashuai; Zhang, Yalin; Shen, Guodong; Yang, Bingchuan; Hu, Xiude; Huang, Xianqiang published the artcile< Metal- and oxidant-free electrochemically promoted oxidative coupling of amines>, Safety of 4-Bromobenzylamine, the main research area is imine diazene preparation; amine electrochem oxidative coupling.

The selective oxidation of amines into imines is a priority research topic in organic synthesis and has attracted much attention over the past few decades. However, the oxidation of amines generally suffers from the drawback of transition-metal, even noble-metal catalysts. Thus, the strategy of metal- and oxidant-free selective synthesis of imines is highly desirable yet largely unmet. This paper unravels a metal-free and external oxidant-free electrochem. strategy for the oxidative coupling methodol. of amines. This general transformation is compatible with various functional amines and led to functionalized imines in moderate to satisfactory yields.

RSC Advances published new progress about Amines Role: RCT (Reactant), RACT (Reactant or Reagent). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Safety of 4-Bromobenzylamine.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Jo, Seonyoung; Kim, Hyunchul; Lee, Taek Seung published the artcile< Decoration of conjugated polyquinoxaline dots on mesoporous TiO2 nanofibers for visible-light-driven photocatalysis>, Safety of 4-Bromobenzylamine, the main research area is conjugated polyquinoxaline dot photocatalytic degradation oxidative coupling reduction; titanium oxide.

The photocatalysis of a heterostructured composite material composed of conjugated polymer dots (CPdots) on the surface of TiO2 nanofibers was investigated in terms of organic dye degradation, photooxidative coupling, and reduction under visible-light irradiation Visible-light harvesting was used to transfer the excited electrons of the CPdots to visible-light-inactive, electrospun, mesoporous TiO2 nanofibers for photocatalysis. The CPdots were electrostatically bound to the TiO2 nanofibers and each CPdot was spatially located with some separation, and thus water and reagents could easily access the photocatalytic TiO2 nanofibers. This resulted in high efficiencies of dye degradation (97%), oxidative coupling (98%), and reduction (90%) under visible lighting. The nanofiber-based photocatalyst provided flexibility and easy handling, enabling repeated use simply by washing after the photocatalytic reaction.

Polymer published new progress about Adsorption (isotherm). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Safety of 4-Bromobenzylamine.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Mothukuri, Ganesh K.; Kale, Sangram S.; Stenbratt, Carl L.; Zorzi, Alessandro; Vesin, Jonathan; Bortoli Chapalay, Julien; Deyle, Kaycie; Turcatti, Gerardo; Cendron, Laura; Angelini, Alessandro; Heinis, Christian published the artcile< Macrocycle synthesis strategy based on step-wise ""adding and reacting"" three components enables screening of large combinatorial libraries>, COA of Formula: C7H8BrN, the main research area is plasma thrombin prothrombin thromboplastin X.

Macrocycles provide an attractive modality for drug development, but generating ligands for new targets is hampered by the limited availability of large macrocycle libraries. We have established a solution-phase macrocycle synthesis strategy in which three building blocks are coupled sequentially in efficient alkylation reactions that eliminate the need for product purification We demonstrate the power of the approach by combinatorially reacting 15 bromoacetamide-activated tripeptides, 42 amines, and 6 bis-electrophile cyclization linkers to generate a 3780-compound library with minimal effort. Screening against thrombin yielded a potent and selective inhibitor (Ki = 4.2 ± 0.8 nM) that efficiently blocked blood coagulation in human plasma. Structure-activity relationship and X-ray crystallog. anal. revealed that two of the three building blocks acted synergistically and underscored the importance of combinatorial screening in macrocycle development. The three-component library synthesis approach is general and offers a promising avenue to generate macrocycle ligands to other targets.

Chemical Science published new progress about Alkylation. 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, COA of Formula: C7H8BrN.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Wang, Hang; Zhang, Qing; Liu, Qing; Zhang, Na; Zhang, Jian-Yong; Fang, Yong-Zheng published the artcile< Bi2S3@NH2-UiO-66-S composites modulated by covalent interfacial reactions boost photodegradation and the oxidative coupling of primary amines>, Safety of 4-Bromobenzylamine, the main research area is bismuth sulfide UiO66 composite catalyst photodegradation oxidative coupling amine; mercapto functionalized UiO66 bismuth sulfide composite preparation photocurrent EIS.

Heterojunctions have attracted much attention due to the efficient separation and conduction of charge carriers in the photocatalytic reactions. However, the interfacial energy barrier between two components still limits the controllable assembly, separation, and conduction of photoexcited charge carriers, and further lower the photocatalytic activity. How to control the assembly of the heterojunction and accelerate the separation and conduction of photogenerated electron-holes by building a more intimate interfacial interaction is an important area of research. Herein, the authors report Bi2S3@NH2-UiO-66-S heterostructures prepared by the covalent interfacial reaction. Novel composites exhibit excellent efficiencies for the photodegradation of methylene blue and the oxidative coupling of benzylamine and its derivatives The turnover frequency is ∼8083μmol gcat-1 h-1. The super photocatalytic performance was attributed to the interfacial compactness by the covalent interfacial reaction. The expansion for the excellent performance was confirmed by UV-visible DRS, photocurrent measurement and EIS.

New Journal of Chemistry published new progress about Charge separation. 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Safety of 4-Bromobenzylamine.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Kandula, Venkata Ramana; Pothireddy, Mohanreddy; Babu, K. Suresh; Kapavarapu, Ravikumar; Dandela, Rambabu; Pal, Manojit published the artcile< Sonochemical synthesis of polyarylated oxazoles as potential cytotoxic agents>, Computed Properties of 3959-07-7, the main research area is polyarylated oxazole preparation ultrasound antitumor human.

The ultrasound assisted facile, rapid and one-pot synthesis of 2-aryl substituted 4,5-diphenyloxazoles I (Ar = C6H5, 4-FC6H4, 3-MeC6H4, etc.,) was achieved via the reaction of com. available benzoin (or 2-hydroxy-2-phenylacetophenone) with benzylamines in the presence of IBX under mild conditions. The methodol. involved initial IBX mediated conversion of benzoin to benzil and then reaction with benzylamine followed by intramol. cyclization (C-O bond formation) and finally aromatization in the presence of air in the same pot. The methodol. afforded a variety of desired products that were assessed for their cytotoxic properties against a number of cancerous and a non-cancerous cell lines. Compounds I (Ar = 4-MeOC6H4), I (Ar = 4-CF3OC6H4) and I (Ar = 3,4-CH3OC6H3) showed promising growth inhibition of these cell lines except the non-cancerous one and interactions with SIRT1 in silico as well as in vitro.

Tetrahedron Letters published new progress about Antitumor agents. 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Computed Properties of 3959-07-7.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary