Category: 3893-18-3

Chiang, Pei-Chen; Kaeobamrung, Juthanat; Bode, Jeffrey W. published the artcile< Enantioselective, Cyclopentene-Forming Annulations via NHC-Catalyzed Benzoin-Oxy-Cope Reactions>, Recommanded Product: 3-(4-Bromophenyl)acrylaldehyde, the main research area is unsaturated aldehyde oxobutenoate chiral triazolium enantioselective benzoin oxy Cope; trisubstituted cyclopentene derivative stereoselective preparation; enantioselective benzoin catalyst chiral nitrogen heterocyclic carbene triazolium; oxy Cope enantioselective catalyst chiral nitrogen heterocyclic carbene triazolium.

Chiral N-heterocyclic carbene catalysts generated from triazolium salts promote the cyclopentene-forming annulation of α,β-unsaturated aldehydes and aryl-4-oxobutenoates with excellent levels of enantioinduction and preference for the cis-1,3,4-trisubstituted cyclopentene diastereomers, e.g., I. Although the observed products could arise by conjugate additions of catalytically generated homoenolates, our mechanistic and stereochem. investigations strongly support a novel reaction manifold featuring an intermol. crossed-benzoin reaction and an NHC-catalyzed oxy-Cope rearrangement.

Journal of the American Chemical Society published new progress about Aldol addition, stereoselective (intramol.). 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Recommanded Product: 3-(4-Bromophenyl)acrylaldehyde.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Hayashi, Yujiro; Hatano, Yutaro; Mori, Naoki published the artcile< Asymmetric Michael Reaction of Malononitrile and α,β-Unsaturated Aldehydes Catalyzed by Diarylprolinol Silyl Ether>, Electric Literature of 3893-18-3, the main research area is diarylprolinol silyl ether preparation; malononitrile unsaturated aldehyde asym Michael.

An asym. Michael reaction of malononitrile and α,β-unsaturated aldehydes catalyzed by a diarylprolinol silyl ether (NC)2CHCH(R)CH2CH(OMe)2 [R = Me, Ph, 2-furyl, etc.] was developed. Michael products were obtained in good yields and with excellent enantioselectivities without the formation of overreaction products. As a malononitrile moiety can be transformed into an alkoxy or amino carbonyl moiety by oxidative transformation, α-chiral esters or amides with all-carbon quaternary centers can be synthesized with excellent enantioselectivities.

Synlett published new progress about Michael reaction. 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Electric Literature of 3893-18-3.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Jiang, Lin; Jin, Wen-Fei; Yu, Liu-Dong; Yuan, Ming-Wei; Li, Hong-Li; Jiang, Deng-Bang; Yuan, Ming-Long published the artcile< Regioselective synthesis of benzonitriles via amino-catalyzed [3+3] benzannulation reaction>, Application of C9H7BrO, the main research area is arylsulfonyl biphenyl carbonitrile preparation green chem regioselective pyrrolidine catalyst; unsaturated aldehyde arylsulfonyl butenenitrile benzannulation.

A straightforward synthesis of benzonitriles I (Ar = Ph, p-ClC6H4, m-NO2-C6H4, etc.; Ar1 = Ph, p-Tol) is achieved via amino-catalyzed [3+3] benzannulation of α,β-unsaturated aldehydes and 4-arylsulfonyl-2-butenenitriles. Using pyrrolidine as an organocatalyst via iminium activation, a series of substituted benzonitriles were obtained in good to high yields in a regioselective manner. This reaction can proceed smoothly under mild reaction conditions and without the aid of any metals, addnl. oxidants, or strong bases, thus making this an efficient and environmentally friendly method to access benzonitriles.

Journal of Chemical Research published new progress about Aromatic nitriles Role: SPN (Synthetic Preparation), PREP (Preparation). 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Application of C9H7BrO.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Gugulothu, Venkanna; Ahemed, Jakeer; Subburu, Mahesh; Yadagiri, Bhongiri; Mittal, Ritu; Prabhakar, Chetti; Pola, Someshwar published the artcile< Evolution of physical and photocatalytic properties of new Zn(II) and Ru(II) complexes>, Recommanded Product: 3-(4-Bromophenyl)acrylaldehyde, the main research area is zinc ruthenium macrocyclic Schiff base complex preparation photocatalytic activity; methylstyrene carbon hydrogen bond activation zinc ruthenium macrocyclic Schiff; aromatic hydrocarbon photooxidation zinc ruthenium macrocyclic Schiff base catalyzed.

Synthesis of Zn(II) and Ru(II) complexes were reported by using N4-macrocyclic Schiff base ligands under solvothermal conditions. The newly synthesized Zn(II) and Ru(II) complexes have been characterized by various physico-chem. techniques such as elemental anal., molar conductance, HRMS, TGA, FESEM, UV-Vis, FT-IR, 1H NMR, and cyclic voltammetry. By using molar conductance studies, the complexes are formulated as [Zn(TPTTP)]Cl2 and [Ru(TPTTP)Cl2]. C-H bond activation of an sp3 group of methylstyrenes (converted into cinnamaldehydes) and C-H bond activation of the sp2 bond of polycyclic aromatic hydrocarbons through photooxidation was examined in the presence of Zn(II) and Ru(II) complexes. Reusable activity studies and photostability of catalyst are investigated by using UV-Vis spectra. Based on the results, higher catalytic activity of [Ru(TPTTP)Cl2] complex than [Zn(TPTTP)]Cl2 complex in both C-H bond activation and photooxidation of aromatic hydrocarbons has been reported.

Polyhedron published new progress about Aldehydes Role: SPN (Synthetic Preparation), PREP (Preparation) (cinnamaldehydes). 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Recommanded Product: 3-(4-Bromophenyl)acrylaldehyde.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Kumar, Mukesh; Chauhan, Pankaj; Valkonen, Arto; Rissanen, Kari; Enders, Dieter published the artcile< Asymmetric Synthesis of Functionalized Tricyclic Chromanes via an Organocatalytic Triple Domino Reaction>, Electric Literature of 3893-18-3, the main research area is asym synthesis functionalized tricyclic chromane organocatalysis triple domino; secondary amine catalyzed domino Michael aldol condensation aldehyde nitrochromene; alpha beta unsaturated aldehyde Michael aldol condensation nitrochromene; crystal mol structure tricyclic chromane.

A highly stereoselective triple domino reaction for the synthesis of functionalized tricyclic chromane scaffolds has been developed. A secondary amine-catalyzed domino Michael/Michael/aldol condensation reaction between aliphatic aldehydes, nitro-chromenes, and α,β-unsaturated aldehydes leads to the formation of synthetically important tricyclic chromanes bearing four contiguous stereogenic centers including a tetrasubstituted carbon in good yields (20-66%) and excellent stereoselectivities (>20:1 dr and >99% ee).

Organic Letters published new progress about Aldol condensation. 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Electric Literature of 3893-18-3.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Wang, Chang-An; Li, Yan-Wei; Han, Yin-Feng; Zhang, Jian-Ping; Wu, Ren-Tao; He, Guo-Fang published the artcile< The ""bottom-up"" construction of chiral porous organic polymers for heterogeneous asymmetric organocatalysis: MacMillan catalyst built-in nanoporous organic frameworks>, Name: 3-(4-Bromophenyl)acrylaldehyde, the main research area is chiral porous polymer organocatalyst enantioselectivity.

Although many porous organic polymers (POPs) embedded with chiral ligand-metal catalytic activities have been examined as heterogeneous asym. catalysts, examples of metal-free stereoselective POP catalysts are very scarce. Herein, we report a “”bottom-up”” strategy used to construct a MacMillan catalyst-embedded chiral porous organic polymer, Mac-CPOPs. The porosity of the Mac-CPOPs frameworks could be adjusted by varying the mol. length of the rigid structural monomers. Due to the high Brunauer-Emmett-Teller sp. surface area and the built-in character of the covalently linked MacMillan catalyst, the Mac-CPOP-2 polymer can be applied as a highly efficient and recoverable heterogeneous organocatalyst in the asym. Diels-Alder reaction, which gives products in good yields and with good enantioselectivity. Moreover, the Mac-CPOP-2 polymer can be reused 6 times for the asym. Diels-Alder reaction without any significant loss of catalytic activity and enantioselectivity.

Polymer Chemistry published new progress about Adsorption. 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Name: 3-(4-Bromophenyl)acrylaldehyde.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Valero, Guillem; Schimer, Jiri; Cisarova, Ivana; Vesely, Jan; Moyano, Albert; Rios, Ramon published the artcile< Highly enantioselective organocatalytic synthesis of piperidines. Formal synthesis of (-)-paroxetine>, SDS of cas: 3893-18-3, the main research area is malonmonoamide unsaturated aldehyde stereoselective cyclization secondary amine catalyst; piperidinone asym synthesis; paroxetine asym formal synthesis.

A highly enantioselective organocatalytic synthesis of piperidines is reported starting from protected malonmonoamides and α,β-unsaturated aldehydes. The reaction is catalyzed by simple and com. available secondary amines, affording the corresponding adducts with high yields and enantioselectivities. Moreover, this reaction is used for the formal synthesis of (-)-paroxetine, a blockbuster drug, in only 3 steps.

Tetrahedron Letters published new progress about Cyclization catalysts, stereoselective. 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, SDS of cas: 3893-18-3.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Kamlar, Martin; Franc, Michael; Cisarova, Ivana; Gyepes, Robert; Vesely, Jan published the artcile< Formal [3+2] cycloaddition of vinylcyclopropane azlactones to enals using synergistic catalysis>, Application of C9H7BrO, the main research area is spirocyclic azlactone enantioselective preparation; enal vinylcyclopropane azlactone cyclization palladium complex chiral amine catalyst.

Asym. cyclization of enals with vinylcyclopropane azlactones efficiently catalyzed by the combination of achiral Pd(0) complexes and chiral secondary amines was reported. Corresponding spirocyclic azlactones I [R1 = t-Bu, Ph; R2 = Et, Ph, 4-O2NC6H4, etc.; stereo = (5S,6S,7S,8R)/(5R,6S,7S,8R)] were produced in high yields with moderate diastereoselectivities and excellent enantioselectivities. This protocol provided an efficient and easily-performed route to spirocyclic scaffolds and densely functionalized cyclopentanes containing quaternary carbon centers.

Chemical Communications (Cambridge, United Kingdom) published new progress about [3+2] Cycloaddition reaction, stereoselective. 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Application of C9H7BrO.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Berger, Martin; Carboni, Davide; Melchiorre, Paolo published the artcile< Photochemical Organocatalytic Regio- and Enantioselective Conjugate Addition of Allyl Groups to Enals>, Quality Control of 3893-18-3, the main research area is prenyl enal preparation regioselective chemoselective enantioselective photochem; unsaturated aldehyde allyl silane allylation organocatalyst; allylation; enantioselectivity; organocatalysis; photochemistry; regioselectivity.

Synthesis of first catalytic enantioselective conjugate addition of allyl groups R1R2C=CH-CH2Si(CH3)3 [R1 = i-Pr, Me, cyclohexyl; R2 = i-Pr, cyclohexyl, n-hexyl, Ph; R1R2 = -(CH2)5-, -(CH2)2O(CH2)2-] (I) to α,β-unsaturated aldehydes ArCH=CHCHO (II) (Ar = Ph, 4-chlorophenyl, 3-methylphenyl, etc.) was reported. The chem. exploits the visible-light-excitation of chiral iminium ions to activate allyl silanes I towards the formation of allylic radicals, which are then intercepted stereoselectively. The underlying radical mechanism of this process overcomes the poor regio- and chemoselectivity that traditionally affects the conjugate allylation of enals II proceeding via polar pathways. Synthesis demonstrates that this organocatalytic strategy could selectively install a valuable prenyl fragment at the β-carbon of enals R1R2C=CHCH2CH(Ar)CH2CHO.

Angewandte Chemie, International Edition published new progress about Aldehydes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Quality Control of 3893-18-3.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Li, Yaxuan; Fu, Yajie; Ren, Chaojie; Tang, Dong; Wu, Ping; Meng, Xu; Chen, Baohua published the artcile< Copper-catalyzed oxidative coupling reaction of α,β-unsaturated aldehydes with amidines: synthesis of 1,2,4-trisubstituted-1H-imidazole-5-carbaldehydes>, Category: bromides-buliding-blocks, the main research area is aldehyde amidine oxidative coupling reaction; imidazole carbaldehyde preparation.

Practical and highly functional group-compatible synthesis of 1,2,4-trisubstituted-1H-imidazole-5-carbaldehydes were developed via copper-catalyzed oxidative coupling of amidines and α,β-unsaturated aldehydes, which features aldehyde preservation, cheap catalysts, as well as high atom economy and mild conditions.

Organic Chemistry Frontiers published new progress about Amidines Role: RCT (Reactant), RACT (Reactant or Reagent). 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Category: bromides-buliding-blocks.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary