Category: 3893-18-3

Ibrahem, Ismail; Breistein, Palle; Cordova, Armando published the artcile< One-Pot Three-Component Catalytic Enantioselective Synthesis of Homoallylboronates>, Application of C9H7BrO, the main research area is copper catalyzed asym reaction diboron unsaturated aldehyde triphenylphosphoranylidene ester; enantioselective synthesis homo allyl boronate.

Authors have developed an efficient, novel one-pot three-component enantioselective reaction between a diboron reagent, α,β-unsaturated aldehydes, and 2-(triphenylphosphoranylidene)acetate esters. The asym. multicomponent reaction proceeds through a β-boration/Wittig sequence to give the corresponding homoallylboronates with high enantiomeric ratios using simple bench-stable chiral amines and copper catalysts. In addition, the study shows that it is possible to merge the catalytic cycles of transition-metal-catalyzed nucleophilic activation of diboron reagents with amine-catalyzed iminium activation of enals to achieve a highly 1,4- and enantioselective β boration of enals. The one-pot expansion of the cocatalytic three-component reaction to the asym. synthesis of homoallylic alcs. was also disclosed. Further development of this type of one-pot multicomponent cocatalytic asym. reaction and its application in total synthesis is ongoing in authors laboratories Thus, three-component trimethylsilyl substituted pyrrolidine amine/PPh3/Cu(OTf)2-catalyzed reaction of cinnamaldehyde with B2pin2 and Ph3P:CHCO2Et in MeOH/Et2O followed by treatment with 2-fluorobenzoic acid gave 65% (S,E)-Et 5-phenyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pent-2-enolate stereoselectively.

Angewandte Chemie, International Edition published new progress about Amines, chiral Role: CAT (Catalyst Use), USES (Uses). 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Application of C9H7BrO.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Siddiqui, I. R.; Rahila; Rai, Pragati; Sagir, Hozeyfa; Waseem, Malik A. published the artcile< Molecular iodine catalysed domino cyclization in aqueous medium: a simple and efficient synthetic route to 1,4-dihydropyridazines>, Formula: C9H7BrO, the main research area is dihydropyridazine preparation green chem; benzylidene phenylhydrazine unsaturated aldehyde cyclization iodine catalyst.

A facile, efficient and environmentally friendly approach has been developed for the diverse synthesis of 1,4-dihydropyridazines I (R = Ph, 4-ClC6H4, 4-MeOC6H4, 1-naphthyl, 4-bromonaphthyl; R1 = Me, Ph, 4-NCC6H4, 3-O2NC6H4, etc.) from (E)-2-benzylidene-1-phenylhydrazines and α,β-unsaturated aldehydes under aqueous condition using mol. iodine as a green and recoverable catalyst. This procedure features low cost and easily available starting materials, an inexpensive and recoverable catalyst, short reaction time, reliable scalability, excellent yield and mild reaction conditions, as well as use of aqueous medium. The scope of this method was thoroughly explored under three different reaction conditions resulting in the generation of a library of title compounds In view of the various advantages of the present investigation, this methodol. gives a convenient and straightforward pathway to construct 1,4-dihydropyridazines in an eco-friendly fashion.

RSC Advances published new progress about Cyclization. 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Formula: C9H7BrO.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Jensen, Kim L.; Poulsen, Pernille H.; Donslund, Bjarke S.; Morana, Fabio; Joergensen, Karl Anker published the artcile< Asymmetric Synthesis of γ-Nitroesters by an Organocatalytic One-Pot Strategy>, Reference of 3893-18-3, the main research area is unsaturated aldehyde nitroalkane diphenyltrimethylsilyloxymethylpyrrolidine enantioselective Michael addition oxidative esterification; gamma arylnitroester Baclofen piperidone stereoselective preparation; enantioselective Michael addition oxidative esterification catalyst diphenyl trimethylsilyloxymethyl pyrrolidine.

An enantioselective synthesis of γ-nitroesters by a one-pot asym. Michael addition/oxidative esterification of α,β-unsaturated aldehydes is presented. The procedure is based on merging the enantioselective organocatalytic nitroalkane addition with an N-bromosuccinimide-based oxidation The γ-nitroesters are obtained in good yields and enantioselectivities, and the method provides an attractive entry to optically active γ-aminoesters, 2-piperidones, and 2-pyrrolidones.

Organic Letters published new progress about Alkanes, nitro Role: RCT (Reactant), RACT (Reactant or Reagent). 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Reference of 3893-18-3.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Mochalov, S. S.; Fedotov, A. N.; Trofimova, E. V.; Gazzaeva, R. A.; Zefirov, N. S. published the artcile< Isomerization of 3-unsubstituted 4,5-dihydroisoxazoles over alumina. A new synthesis of β-hydroxy nitriles>, Application In Synthesis of 3893-18-3, the main research area is aryl hydroxypropane nitrile one pot synthesis; arylcyclopropane nitrosation dihydroisoxazole isomerization alumina catalyst chromatog.

3-Unsubstituted 4,5-dihydroisoxazoles obtained by nitrosation of arylcyclopropanes are capable of undergoing efficient isomerization into 3-aryl-3-hydroxypropanenitriles during chromatog. on alumina.

Russian Journal of Organic Chemistry published new progress about Hydroxynitriles Role: SPN (Synthetic Preparation), PREP (Preparation). 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Application In Synthesis of 3893-18-3.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Companyo, Xavier; Alba, Andrea-Nekane; Cardenas, Francisco; Moyano, Albert; Rios, Ramon published the artcile< Asymmetric Organocatalytic Cyclopropanation - Highly Stereocontrolled Synthesis of Chiral Cyclopropanes with Quaternary Stereocenters>, SDS of cas: 3893-18-3, the main research area is unsaturated aldehyde bromo keto ester chiral silyloxymethylpyrrolidine asym cyclopropanation; cyclopropane carboxaldehyde derivative stereoselective preparation; chiral silyloxymethylpyrrolidine asym cyclopropanation organocatalyst.

A convenient and novel domino reaction for the synthesis of highly functionalized cyclopropanes is reported. The addition of 2-bromo keto esters to a variety of α,β-unsaturated aldehydes catalyzed by secondary amines leads to chiral cyclopropanes, e.g., I, with three stereogenic carbon atoms, including one quaternary stereocenter, in a highly stereocontrolled fashion.

European Journal of Organic Chemistry published new progress about Cycloalkanes Role: SPN (Synthetic Preparation), PREP (Preparation). 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, SDS of cas: 3893-18-3.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Jayabharathi, Jayaraman; Sarojpurani, Elayaperumal; Thanikachalam, Venugopal; Jeeva, Palanivel published the artcile< Far-Field Enhancement by Silver Nanoparticles in Organic Light Emitting Diodes Based on Donor-π-Acceptor Chromophore>, Computed Properties of 3893-18-3, the main research area is LED organic donor pi acceptor chromophore silver nanoparticle; diode light emitting organic donor acceptor chromophore silver nanoparticle; electroluminescent device organic donor pi acceptor chromophore silver nanoparticle.

Enhancement in brightness and luminous efficiency was harvested by the incorporation of Ag nanoparticles (Ag NPs) at ITO: 4,4′-bis[N-(1-naphthyl)-N-phenylamino]biphenyl (NPB) interface, using 4′-(1-(4-methoxyphenyl)-1H-phenanthro[9,10-d]imidazole-2-yl)styryl-N,N-diphenyl[1,1′-biphenyl]-4-amine (MPID-TPA) as emissive layer. The enhanced device performance was obtained with 35 nm distance between Ag NPs and emissive material (MPID-TPA). The Ag NPs deposited devices easily inject holes into NPB layer that results in stabilized vacuum level of anode and increase of the c.d. of OLEDs. The combined effect of far-field plasmonic coupling and hole injection ability of Ag NPs at ITO:HTL interface is the probable reason for the enhancement. A turn-off emission of MPID by Ag NPs and turn-on emission of MPID with the Ag NPs etched by H2O2 formed from the enzymic oxidation of glucose were analyzed.

Industrial & Engineering Chemistry Research published new progress about Chromophores. 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Computed Properties of 3893-18-3.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Meazza, Marta; Rios, Ramon published the artcile< Synergistic Catalysis: Enantioselective Ring Expansion of Vinyl Cyclopropanes Combining Four Catalytic Cycles for the Synthesis of Highly Substituted Spirocyclopentanes Bearing up to Four Stereocenters>, Safety of 3-(4-Bromophenyl)acrylaldehyde, the main research area is spirocyclopentane preparation; aldehyde vinyl cyclopropane cascade enantioselective ring expansion synergistic catalysis; cascade reaction; cyclopentanes; enantioselective; palladium; synergistic catalysis.

A double synergistic cascade reaction is reported, combining transition metal and amine catalysis. The reaction between vinyl cyclopropanes and enals renders the final cyclopentane derivatives, e.g. I, in excellent yields and stereoselectivities.

Chemistry – A European Journal published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Safety of 3-(4-Bromophenyl)acrylaldehyde.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Hong, Liang; Sun, Wangsheng; Liu, Chunxia; Wang, Lei; Wang, Rui published the artcile< Asymmetric organocatalytic N-alkylation of indole-2-carbaldehydes with α,β-unsaturated aldehydes: one-pot synthesis of chiral pyrrolo[1,2-a]indole-2-carbaldehydes>, Recommanded Product: 3-(4-Bromophenyl)acrylaldehyde, the main research area is pyrroloindolecarbaldehyde asym preparation; indolecarbaldehyde unsaturated aldehyde Michael addition cyclization diphenylsilyloxymethylpyrrolidine.

Diphenylprolinol trimethylsilyl ether-catalyzed asym. aza-Michael addition/aldol addition of indole-2-carboxaldehyde with unsaturated aldehydes is described. A series of chiral pyrrolo[1,2-a]indole-2-carbaldehydes were obtained in good yields with excellent stereoselectivities.

Chemistry – A European Journal published new progress about Cyclization. 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Recommanded Product: 3-(4-Bromophenyl)acrylaldehyde.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Cohen, Daniel T.; Cardinal-David, Benoit; Roberts, John M.; Sarjeant, Amy A.; Scheidt, Karl A. published the artcile< NHC-catalyzed/titanium(IV)-mediated highly diastereo- and enantioselective dimerization of enals>, Recommanded Product: 3-(4-Bromophenyl)acrylaldehyde, the main research area is heterocyclic carbene catalyst titanium diastereoselective enantioselective dimerization enal; unsaturated aldehyde diastereoselective enantioselective dimerization; cyclopentene stereoselective preparation.

An NHC-catalyzed diastereo- and enantioselective dimerization of enals has been developed. The use of Ti(Oi-Pr)4 is a key element for the reactivity and selectivity of this process. The cyclopentenes are obtained with high levels of diastereo- and enantioselectivity and their synthetic utility is demonstrated by functionalization of the product alkene.

Organic Letters published new progress about Carbenes (methylene derivatives) Role: CAT (Catalyst Use), USES (Uses) (heterocyclic carbene). 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Recommanded Product: 3-(4-Bromophenyl)acrylaldehyde.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Hong, Liang; Liu, Chunxia; Sun, Wangsheng; Wang, Lei; Wong, Kwokyin; Wang, Rui published the artcile< Organocatalytic Enantioselective Friedel-Crafts Alkylation of 4,7-Dihydroindoles with α,β-Unsaturated Aldehydes: An Easy Access to 2-Substituted Indoles>, Recommanded Product: 3-(4-Bromophenyl)acrylaldehyde, the main research area is dihydroindole unsaturated aldehyde chiral diarylprolinol trimethylsilyl ether; enantioselective Friedel Crafts alkylation benzoquinone oxidation; substituted dihydroindole indole stereoselective preparation; Friedel Crafts alkylation enantioselective catalyst chiral diarylprolinol trimethylsilyl ether.

An enantioselective Friedel-Crafts alkylation of 4,7-dihydroindoles and α,β-unsaturated aldehydes has been developed. The process is promoted by diphenylprolinol ether to afford 2-substituted 4,7-dihydroindoles, e.g., I, in high yields and enantioselectivities. After a subsequent oxidation of the products, the optically active 2-substituted indoles could be obtained smoothly in high yields without any loss of enantioselectivity.

Organic Letters published new progress about Friedel-Crafts reaction (enantioselective). 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Recommanded Product: 3-(4-Bromophenyl)acrylaldehyde.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary