Category: 3141-27-3

《Investigation into the influence of an acrylic acid acceptor in organic D-π-A sensitizers against phototoxicity》 was published in Bioorganic & Medicinal Chemistry in 2020. These research results belong to Fuse, Shinichiro; Moriya, Wataru; Sato, Shinichi; Nakamura, Hiroyuki. Safety of 2,5-Dibromothiophene The article mentions the following:

Photodynamic therapy (PDT) is a non-invasive, selective, and cost-effective cancer therapy. We previously reported that thiophene-based organic D-π-A sensitizers consist of an electron-donating (D) moiety, a π-conjugated bridge (π) moiety, and an electron-accepting (A) moiety, and are readily accessible and stable templates for photosensitizers that could be used in PDT. In addition, acrylic acid acceptor-containing photosensitizers exert a high level of phototoxicity. This study was an investigation into 1) the possibility of increasing phototoxicity by introducing another carboxyl group or by replacing a carboxyl group with a pyridinium group, and 2) the importance of an alkene in the acrylic acid acceptor for phototoxicity. A review of the design, synthesis, and evaluation of sensitizers revealed that neither dicarboxylic acid nor pyridinium photosensitizers enhance phototoxicity. An evaluation of a photosensitizer without an alkene in the acrylic acid moiety revealed that the alkene was not indispensable in the pursuit of phototoxicity. The obtained results provided new insight into the design of ideal D-π-A photosensitizers for PDT. After reading the article, we found that the author used 2,5-Dibromothiophene(cas: 3141-27-3Safety of 2,5-Dibromothiophene)

2,5-Dibromothiophene(cas: 3141-27-3) , is mainly used as pharmaceutical intermediate and synthesis intermediate. 2,5-Dibromothiophene may be used in the preparation of soluble α,ω-diformyl-a-oligothiophenes.Safety of 2,5-Dibromothiophene

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Quertinmont, Jean; Beaujean, Pierre; Stiennon, Julien; Aidibi, Youssef; Leriche, Philippe; Rodriguez, Vincent; Sanguinet, Lionel; Champagne, Benoit published their research in Journal of Physical Chemistry B in 2021. The article was titled 《Combining Benzazolo-Oxazolidine Twins toward Multi-state Nonlinear Optical Switches》.Computed Properties of C4H2Br2S The article contains the following contents:

Mol. switches are chem. compounds exhibiting the possibility of reversible transformations between their different forms accompanied by a modification in their properties. Among these, switching of multi-addressable Benzazolo-OXazolidines (BOXs) from a closed form to an open form results in drastic modifications in their linear and nonlinear optical properties. Here, we target mols. containing two identical BOX units (DiBOX) connected by different π-conjugated linkers, and we combine synthesis, UV/visible absorption, and hyper-Rayleigh scattering (HRS) measurements, together with d. functional theory (DFT) calculations Three derivatives have been considered, which differ by the linker: (i) a bithiophene moiety (Bt), (ii) two 3,4-ethylenedioxythiopene (EDOT) units, and (iii) a triad composed of an EDOT-thiophene-EDOT sequence (TtO). As a matter of fact, these systems can adopt three states (CF-CF, POF-POF, and CF-POF) depending on the closed form (CF) or the protonated open form (POF) of each BOX unit. Despite chem. equivalence, stepwise switching of such systems under the addition of a chem. acid or an oxidant has been exptl. evidenced for two of them (DiBOX-Bt and DiBOX-TtO). Then, DFT calculations show that the first BOX opening leads to the formation of a push-pull π-conjugated segment, exhibiting a huge increase in the first hyperpolarizability (β) and a bathochromic shift with respect to the fully closed form. On the contrary, the second BOX opening induces not only a slight bathochromic shift but also a reduction in their β values conferring the great and uncommon abilities to modulate their linear and nonlinear properties over three discrete levels. Among these results, those on DiBOX-Bt agree with the exptl. data obtained by HRS measurements and further shed light on their structure-property relationship. The results came from multiple reactions, including the reaction of 2,5-Dibromothiophene(cas: 3141-27-3Computed Properties of C4H2Br2S)

2,5-Dibromothiophene(cas: 3141-27-3) , is mainly used as pharmaceutical intermediate and synthesis intermediate. 2,5-Dibromothiophene may be used in the preparation of soluble α,ω-diformyl-a-oligothiophenes.Computed Properties of C4H2Br2S

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2022,Wang, Hang; Lu, Hao; Chen, Ya-Nan; Ran, Guangliu; Zhang, Andong; Li, Dawei; Yu, Na; Zhang, Zhe; Liu, Yahui; Xu, Xinjun; Zhang, Wenkai; Bao, Qinye; Tang, Zheng; Bo, Zhishan published an article in Advanced Materials (Weinheim, Germany). The title of the article was 《Chlorination Enabling a Low-Cost Benzodithiophene-Based Wide-Bandgap Donor Polymer with an Efficiency of over 17%》.Electric Literature of C4H2Br2S The author mentioned the following in the article:

Three regioregular benzodithiophene-based donor-donor (D-D)-type polymers (PBDTT, PBDTT1Cl, and PBDTT2Cl) are designed, synthesized, and used as donor materials in organic solar cells (OSCs). Because of the weak intramol. charge-transfer effect, these polymers exhibit large optical bandgaps (>2.0 eV). Among these three polymers, PBDTT1Cl exhibits more ordered and closer mol. stacking, and its devices demonstrate higher and more balanced charge mobilities and a longer charge-separated state lifetime. As a result of these comprehensive benefits, PBDTT1Cl-based OSCs give a very impressive power conversion efficiency (PCE) of 17.10% with a low nonradiative energy loss (0.19 eV). Moreover, PBDTT1Cl also possesses a low figure-of-merit value and good universality to match with different acceptors. This work provides a simply and efficient strategy to design low-cost high-performance polymer donor materials. In the part of experimental materials, we found many familiar compounds, such as 2,5-Dibromothiophene(cas: 3141-27-3Electric Literature of C4H2Br2S)

2,5-Dibromothiophene(cas: 3141-27-3) , is mainly used as pharmaceutical intermediate and synthesis intermediate. 2,5-Dibromothiophene may be used in the preparation of soluble α,ω-diformyl-a-oligothiophenes.Electric Literature of C4H2Br2S

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2022,Oe, Yuno; Yoshida, Ryuhei; Tanaka, Airi; Adachi, Akiya; Ishibashi, Yuichiro; Okazoe, Takashi; Aikawa, Kohsuke; Hashimoto, Takuya published an article in Journal of the American Chemical Society. The title of the article was 《An N-Fluorinated Imide for Practical Catalytic Imidations》.HPLC of Formula: 3141-27-3 The author mentioned the following in the article:

Hherein the development of a novel N-fluorinated imide, N-fluoro-N-(fluorosulfonyl)carbamate (NFC), by which the attached imide moiety acted as a modular synthetic handle for one-step derivatization to amines, sulfonamides, and sulfamides was reported. Furthermore, this study revealed the superior reactivity of NFC as showcased in a copper-catalyzed imidation of benzene derivatives and imidocyanation of aliphatic alkenes, overcoming the limitation of NFSI-mediated reactions.2,5-Dibromothiophene(cas: 3141-27-3HPLC of Formula: 3141-27-3) was used in this study.

2,5-Dibromothiophene(cas: 3141-27-3) , is mainly used as pharmaceutical intermediate and synthesis intermediate. 2,5-Dibromothiophene may be used as starting reagent for the synthesis of α,α′-didecylquater-, -quinque- and -sexi-thiophenes.HPLC of Formula: 3141-27-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Mechanistic Insights into the Triplet Sensitized Photochromism of Diarylethenes》 was published in Chemistry – A European Journal in 2020. These research results belong to Fredrich, Sebastian; Morack, Tobias; Sliwa, Michel; Hecht, Stefan. Reference of 2,5-Dibromothiophene The article mentions the following:

Operating photoswitchable mols. repetitively and reliably is crucial for most of their applications, in particular in (opto)electronic devices, and related to reversibility and fatigue resistance, which both critically depend on the photoisomerization mechanism defined by the substitution pattern. Two diarylethene photoswitches bearing biacetyl triplet sensitizers either at the periphery or at the core were investigated using both stationary as well as transient UV/Vis absorption spectroscopy ranging from the femtosecond to the microsecond time scale. The diarylethene with two biacetyl moieties at the periphery is switching predominantly from the triplet excited state, giving rise to an enhanced fatigue resistance. In contrast, the diarylethene bearing one diketone at the photoreactive inner carbon atom cyclizes from the singlet excited state and shows significantly higher quantum yields for both cyclization and cycloreversion. In the part of experimental materials, we found many familiar compounds, such as 2,5-Dibromothiophene(cas: 3141-27-3Reference of 2,5-Dibromothiophene)

2,5-Dibromothiophene(cas: 3141-27-3) , is mainly used as pharmaceutical intermediate and synthesis intermediate. 2,5-Dibromothiophene may be used in the preparation of soluble α,ω-diformyl-a-oligothiophenes.Reference of 2,5-Dibromothiophene

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Bugday, Nesrin; Khan, Siraj; Yasar, Sedat; Ozdemir, Ismail published their research in Journal of Organometallic Chemistry in 2021. The article was titled 《C-H Bond activation of 2-isobutylthiazole at C5 position catalysed by Pd-N-heterocyclic carbene complexes》.Quality Control of 2,5-Dibromothiophene The article contains the following contents:

A highly efficient and effective protocol was developed for the synthesis of C5-(hetero)arylated 2-isobutylthiazole derivatives I [Ar = Ph, 4-MeC6H4, 1-naphthyl, etc.]. Four different palladium N-heterocyclic carbene (Pd-NHCs) complexes [Pd(μ-Cl)Cl(SIMes)]2, (LCl2Pd-SIMes) (L = PPh3; L = Py; L = 3-CHO-Py) were synthesized and used for the first time as a catalysts in direct C-H arylation reaction of 2-isobutylthiazole at C5 position. Utilizations of these catalytic systems, the arylation of 2-isobutylthiazole with substituted (hetero)aryl bromides efficiently proceeded at low catalyst loading (1 mol%) and without any additives such as PivOH under argon or aerobic conditions at 120°C in a short time. Different substituted (hetero)aryl bromides, even some deactivated or highly sterically hindered (hetero)arylbromides, with a wide range of functional groups were successfully utilized under the optimum reaction conditions. In all cases, the C5 arylated 2-isobutylthiazoles were obtained in moderate to excellent yields. The experimental part of the paper was very detailed, including the reaction process of 2,5-Dibromothiophene(cas: 3141-27-3Quality Control of 2,5-Dibromothiophene)

2,5-Dibromothiophene(cas: 3141-27-3) , is mainly used as pharmaceutical intermediate and synthesis intermediate. 2,5-Dibromothiophene may be used in the preparation of soluble α,ω-diformyl-a-oligothiophenes.Quality Control of 2,5-Dibromothiophene

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Wang, Ya-Hao; Yan, Feng; Li, Dong-Fang; Xi, Yan-Feng; Cao, Rui; Zheng, Ju-Fang; Shao, Yong; Jin, Shan; Chen, Jing-Zhe; Zhou, Xiao-Shun published their research in Journal of Physical Chemistry Letters in 2021. The article was titled 《Enhanced gating performance of single-molecule conductance by heterocyclic molecules》.Safety of 2,5-Dibromothiophene The article contains the following contents:

Enhancing the gating performance of single-mol. conductance is significant for realizing mol. transistors. Herein, we report a new strategy to improve the electrochem. gating efficiency of single-mol. conductance with fused mol. structures consisting of heterocyclic rings of furan, thiophene, or selenophene. One order magnitude of gating ratio is achieved within a potential window of 1.2 V for the selenophene-based mol., which is significantly greater than that of other heterocyclic and benzene ring mols. This is caused by the different electronic structures of heterocyclic mols. and transmission coefficients T(E), and preliminary resonance tunneling is achieved through the HOMO at high potential. The current work exptl. shows that electrochem. gating performance can be significantly modulated by the alignment of the conducting orbital of the heterocyclic mol. relative to the metal Fermi energy. In the experimental materials used by the author, we found 2,5-Dibromothiophene(cas: 3141-27-3Safety of 2,5-Dibromothiophene)

2,5-Dibromothiophene(cas: 3141-27-3) , is mainly used as pharmaceutical intermediate and synthesis intermediate. 2,5-Dibromothiophene may be used as starting reagent for the synthesis of α,α′-didecylquater-, -quinque- and -sexi-thiophenes.Safety of 2,5-Dibromothiophene

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Application of 3141-27-3In 2021 ,《Donor-Acceptor-Donor Thienopyrazine-Based Dyes as NIR-Emitting AIEgens》 was published in European Journal of Organic Chemistry. The article was written by Goti, Giulio; Calamante, Massimo; Coppola, Carmen; Dessi, Alessio; Franchi, Daniele; Mordini, Alessandro; Sinicropi, Adalgisa; Zani, Lorenzo; Reginato, Gianna. The article contains the following contents:

Organic Near-IR luminophores have found broad application as functional materials, but the development of efficient NIR emitters is still a challenging goal. Here we report on a new class of thieno[3,4-b]pyrazine-based NIR emitting materials with Aggregation Induced Emission (AIE) properties. The dyes feature a donor-acceptor-donor (D-A-D) structure, with a thienopyrazine acceptor core connected to two triarylamine donor groups bearing a tetraphenylethylene (TPE) moiety. Fast and efficient synthesis allowed the modular preparation of three dyes of tunable absorption and emission profiles. These constructs were extensively characterized by spectroscopic studies in different solvents, which revealed intense light-harvesting ability and emissions in the deep-red and NIR region with large Stokes shift values. Remarkably, the dyes exhibited AIE properties, retaining emissive ability in the aggregate state, thus emerging as attractive materials for their potential application in the development of luminescent devices. In the experiment, the researchers used 2,5-Dibromothiophene(cas: 3141-27-3Application of 3141-27-3)

2,5-Dibromothiophene(cas: 3141-27-3) , is mainly used as pharmaceutical intermediate and synthesis intermediate. 2,5-Dibromothiophene polymerizes by debromination with magnesium catalyzed by nickel compounds to form poly(2,5- thienylene) .Application of 3141-27-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2022,Zhang, Yuhang; Li, Rui; Chang, Lijing; Ma, Yang; Hou, Yanjun; Niu, Haijun published an article in Macromolecular Chemistry and Physics. The title of the article was 《Electropolymerization of thiophene-based monomers with different spatial structures: the impact of monomer structure on electrochromic properties》.HPLC of Formula: 3141-27-3 The author mentioned the following in the article:

The development prospect of conductive electrochromic (EC) polymers requires the design of polymers with high performance and good stability. Here, a new scheme is designed to enhance EC properties by adjusting the monomer mol. structure. Four monomers with different structures based on thiophene and 3,4-ethylenedioxythiophene (EDOT) are designed and synthesized. The corresponding polymer films (P1, P2, P3, and P4) are prepared by electrochem. polymerization at low applied potential. The spatial structure-performance relationship of precursors with different structures and polymers is systematically discussed. In the electropolymerization experiments, it is noted that P3 has no EC property. This may be connected to the spatial structure of P3 polymerization which is not suitable for charge transporting. By contrast, the other three polymers exhibit excellent electrochem. properties. The diffusion rate higher of P1 has also been corroborated by using electrochem. impedance spectroscopy (EIS) spectrum. The P1 film has the best stability and fastest colorized time among the samples; such superior electrochem. property may be associated with the closely stacked formed by the unique sheet-like spatial structure. The design of the space structure has a significant impact on the optical and elec. properties of the polymer film. In the experiment, the researchers used many compounds, for example, 2,5-Dibromothiophene(cas: 3141-27-3HPLC of Formula: 3141-27-3)

2,5-Dibromothiophene(cas: 3141-27-3) , is mainly used as pharmaceutical intermediate and synthesis intermediate. 2,5-Dibromothiophene may be used as starting reagent for the synthesis of α,α′-didecylquater-, -quinque- and -sexi-thiophenes.HPLC of Formula: 3141-27-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Selective Mechanochemical Monoarylation of Unbiased Dibromoarenes by In-situ Crystallization》 was published in Journal of the American Chemical Society in 2020. These research results belong to Seo, Tamae; Kubota, Koji; Ito, Hajime. Safety of 2,5-Dibromothiophene The article mentions the following:

Palladium-catalyzed Suzuki-Miyaura cross-coupling reactions of liquid, unbiased dibromoarenes under mechanochem. conditions selectively afford the monoarylated products Ar-Ar1 [Ar = 2-BrC6H4, 2-Br-4,5-di-FC6H2, 4-Br-3-thienyl; Ar1 = Ph, 4-MeOC6H4, 2-naphthyl, etc.]. The lower reactivity of the crystalline monoarylated products relative to the liquid starting materials should be attributed predominantly to the low diffusion efficiency of the former in the re-action mixture, which results in a selective monoarylation. The present study sheds light on a novel approach using in-situ phase transitions in solids to design selective organic transfor-mations that are difficult to achieve via conventional solution-based synthesis. In the experiment, the researchers used many compounds, for example, 2,5-Dibromothiophene(cas: 3141-27-3Safety of 2,5-Dibromothiophene)

2,5-Dibromothiophene(cas: 3141-27-3) , is mainly used as pharmaceutical intermediate and synthesis intermediate. 2,5-Dibromothiophene may be used in the preparation of soluble α,ω-diformyl-a-oligothiophenes.Safety of 2,5-Dibromothiophene

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary