Category: 3141-27-3

In 2022,Ohshita, Joji; Ohta, Akiyoshi; Saadom, Siti Zulaikha Binti; Adachi, Yohei; Murakami, Hideki; Haino, Takeharu published an article in Polymer Journal (Tokyo, Japan). The title of the article was 《Synthesis and optical properties of disiloxane-linked decathiophene and dodecathiophene polymers》.Name: 2,5-Dibromothiophene The author mentioned the following in the article:

Disiloxane-linked decathiophene and dodecathiophene polymers were prepared and their optical properties were examined Compared with the monosilane-linked congeners reported previously, these polymers showed slightly red shifted absorption and PL bands in solution Interestingly, the PL bands were red shifted when the spectra were measured in film, and the red shifts became pronounced as the silicon linkers were elongated from monosilane to disiloxane. This is likely due to the enhanced aggregation of the oligothiophene units, reflecting the improved flexibility of the silicon linkers. After reading the article, we found that the author used 2,5-Dibromothiophene(cas: 3141-27-3Name: 2,5-Dibromothiophene)

2,5-Dibromothiophene(cas: 3141-27-3) , is mainly used as pharmaceutical intermediate and synthesis intermediate. 2,5-Dibromothiophene may be used in the preparation of soluble α,ω-diformyl-a-oligothiophenes.Name: 2,5-Dibromothiophene

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Recommanded Product: 3141-27-3In 2022 ,《Synthesis, molecular docking, and biological evaluation of 5-alkyl(aryl)-2-isobutylthiazole derivatives as α-amylase, α-glucosidase, and protein kinase inhibitors》 was published in Applied Organometallic Chemistry. The article was written by Khan, Siraj; Bugday, Nesrin; Rehman, Asim Ur; Haq, Ihsan Ul; Yasar, Sedat; Ozdemir, Ismail. The article contains the following contents:

A series of 18 biol. active C5-arylated-2-isobutylthiazoles (aryl = Ph, 4-MeCOC6H4, 4-methyl-1-naphthyl, 5-formyl-2-furyl, etc.) was synthesized from 2-isobutylthiazole and the corresponding aryl bromides via C-H bond activation using Pd-NHC complexes [Pd(μ-Cl)Cl(NHC)]2 [NHC = 1,3-bis(2,6-dimethylphenyl)imidazolylidene] and [LCl2Pd-NHC] (L = PPh3, pyridine, 3-formylpyridine). All Pd-NHC complexes were prepared and characterized by 1H NMR, 13C NMR and FTIR spectroscopy, quadrupole-time of flight-liquid chromatog./mass spectroscopy (Q-TOF-LC/MS), gas chromatog.-mass spectrometry (GCMS), and m.p. techniques. The physicochem. properties, pharmacokinetics and drug-likeness of the thiazole products were calculated by SwissADME. PkCSM database was used to calculated the toxicity profile. Almost all the compounds showed no to low toxicity. All the products were addnl. assessed in vitro for their antidiabetic potential using α-amylase and α-glucosidase inhibitory activities. Except for 7 compounds, the prepared thiazoles showed good α-glucosidase inhibitory potential (IC50 7.17 ± 0.201 to 74.08 ± 0.244μg/mL) when compared with acarbose standard (IC50 16.59 ± 0.135μg/mL). All compounds had moderate to good inhibitory potential against the α-amylase enzyme, with IC50 values ranging from 12.00 ± 0.289 to 76.15 ± 0.477μg/mL. The protein kinase inhibition potential was determined for the first time, and 7 compounds showed activity with the zone of inhibition in the range of 9 ± 1.3 to 19 ± 1.5 mm. The ligands and active site binding interactions of α-glucosidase, α-amylase, and protein kinase enzymes were also studied using mol. modeling. In the experiment, the researchers used many compounds, for example, 2,5-Dibromothiophene(cas: 3141-27-3Recommanded Product: 3141-27-3)

2,5-Dibromothiophene(cas: 3141-27-3) , is mainly used as pharmaceutical intermediate and synthesis intermediate. 2,5-Dibromothiophene polymerizes by debromination with magnesium catalyzed by nickel compounds to form poly(2,5- thienylene) .Recommanded Product: 3141-27-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Role of Substituents at 3-position of Thienylethynyl Spacer on Electronic Properties in Diruthenium(II) Organometallic Wire-like Complexes》 was written by Roy, Sourav Saha; Chowdhury, Sabyasachi Roy; Mishra, Sabyashachi; Patra, Sanjib K.. Synthetic Route of C4H2Br2S And the article was included in Chemistry – An Asian Journal in 2020. The article conveys some information:

Organometallic complexes [Cl(dppe)2Ru-C C-(3-R-C4H2S)-C C-Ru(dppe)2Cl] (3-R-C4H2S = 3-substituted thienyl moiety; R = -H, -C2H5, -Pr, -Bu, -C6H13, -OMe, -CN in 5a-5g, resp.) were synthesized by systematic variation of 3-substituents at the thienylethynyl bridging unit. The diruthenium(II) wire-like complexes (5a-5g) were achieved by the reaction of thienylethynyl bridging units, Hc C-(3-R-C4H2S)-C CH (4 a-4 g) with cis-[Ru(dppe)2Cl2]. The wire-like diruthenium(II) complexes undergo two consecutive electrochem. oxidation processes in the potential range of 0.0-0.8 V. The wave separation between the two redox waves is greatly influenced by the substituents at the 3-position of the thienylethynyl. Thus, the substitution on 3-position of the thienylethynyl bridging unit plays a pivotal role for tuning the electronic properties. To understand the electronic behavior, d. functional theory (DFT) calculations of the selected diruthenium wire-like complexes (5a-5e) with different alkyl appendages were performed. The theor. data demonstrate that incorporation of alkyl groups to the thienylethynyl entity leaves unsym. spin densities, thus affecting the electronic properties. The voltammetric features of the other two Ru(II) alkynyl complexes 5f and 5g (with -OMe and -CN group, resp.) show an apparent dependence on the electronic properties. The electronic properties in the redox conjugate, (5a+) with Kc of 3.9 × 106 are further examined by UV-visible-NIR and FTIR studies, showing optical responses in NIR region along with changes in -Ru-C C- vibrational stretching frequency. The origin of the observed electronic transition was assigned based on time-dependent DFT (TDDFT) calculations In the part of experimental materials, we found many familiar compounds, such as 2,5-Dibromothiophene(cas: 3141-27-3Synthetic Route of C4H2Br2S)

2,5-Dibromothiophene(cas: 3141-27-3) , is mainly used as pharmaceutical intermediate and synthesis intermediate. 2,5-Dibromothiophene may be used as starting reagent for the synthesis of α,α′-didecylquater-, -quinque- and -sexi-thiophenes.Synthetic Route of C4H2Br2S

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Computed Properties of C4H2Br2SIn 2022 ,《Microwave-Assisted Synthesis of 2-Aryl and 2,5-Diarylthiophene Derivatives via Suzuki-Miyaura Cross-Coupling Using Novel Palladium Complex as a Catalyst》 appeared in Polycyclic Aromatic Compounds. The author of the article were Khormi, Afaf Y.; Farghaly, Thoraya. A.; Shaaban, Mohamed R.. The article conveys some information:

A novel phosphine-free pyrimidine-based palladium(II) complex was synthesized from easily accessible starting materials and its ability to be a catalyst for cross-coupling reactions namely, Suzuki-Miyaura (SMC) was investigated. The structure of the new formamidinyl pyrimidine-based complex was elucidated by using spectroscopic as well as phys. characterization techniques. The novel palladium(II) complex showed its applicability as a catalyst for SMC of 2-bromothiophene and 2,5-dibromothiophene with arylboronic acids under conventional and microwaves irradiation conditions. The developed catalytic system exhibited reasonable catalytic activity to obtain 2-aryl and 2,5-diarylthiophene derivatives using mild reaction conditions. The results came from multiple reactions, including the reaction of 2,5-Dibromothiophene(cas: 3141-27-3Computed Properties of C4H2Br2S)

2,5-Dibromothiophene(cas: 3141-27-3) , is mainly used as pharmaceutical intermediate and synthesis intermediate. 2,5-Dibromothiophene polymerizes by debromination with magnesium catalyzed by nickel compounds to form poly(2,5- thienylene) .Computed Properties of C4H2Br2S

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2022,Kaya, Kemal; Khalil, Mohammed; Fetrow, Benjamin; Fritz, Hugh; Jagadesan, Pradeepkumar; Bondu, Virginie; Ista, Linnea; Chi, Eva Y.; Schanze, Kirk S.; Whitten, David G.; Kell, Alison published an article in ACS Applied Materials & Interfaces. The title of the article was 《Rapid and Effective Inactivation of SARS-CoV-2 with a Cationic Conjugated Oligomer with Visible Light: Studies of Antiviral Activity in Solutions and on Supports》.Reference of 2,5-Dibromothiophene The author mentioned the following in the article:

This paper presents results of a study of a new cationic oligomer that contains end groups and a chromophore affording inactivation of SARS-CoV-2 by visible light irradiation in solution or as a solid coating on paper wipes and glass fiber filtration substrates. A key finding of this study is that the cationic oligomer with a central thiophene ring and imidazolium charged groups gives outstanding performance in both the killing of E. coli bacterial cells and inactivation of the virus at very short times. Our introduction of cationic N-Me imidazolium groups enhances the light activation process for both E. coli and SARS-CoV-2 but dampens the killing of the bacteria and eliminates the inactivation of the virus in the dark. For the studies with this oligomer in solution at a concentration of 1μg/mL and E. coli, we obtain 3 log killing of the bacteria with 10 min of irradiation with LuzChem cool white lights (mimicking indoor illumination). With the oligomer in solution at a concentration of 10μg/mL, we observe 4 log inactivation (99.99%) in 5 min of irradiation and total inactivation after 10 min. The oligomer is quite active against E. coli on oligomer-coated paper wipes and glass fiber filter supports. The SARS-CoV-2 is also inactivated by oligomer-coated glass fiber filter papers. This study indicates that these oligomer-coated materials may be very useful as wipes and filtration materials. In the part of experimental materials, we found many familiar compounds, such as 2,5-Dibromothiophene(cas: 3141-27-3Reference of 2,5-Dibromothiophene)

2,5-Dibromothiophene(cas: 3141-27-3) , is mainly used as pharmaceutical intermediate and synthesis intermediate. 2,5-Dibromothiophene may be used as starting reagent for the synthesis of α,α′-didecylquater-, -quinque- and -sexi-thiophenes.Reference of 2,5-Dibromothiophene

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Configurationally Random Polythiophene for Improved Polymer Ordering and Charge-Transporting Ability》 was published in ACS Applied Materials & Interfaces in 2020. These research results belong to Opoku, Henry; Lee, Ji Hyeon; Nketia-Yawson, Benjamin; Bae, Seunghwan; Lee, Jae-Joon; Ahn, Hyungju; Jo, Jea Woong. COA of Formula: C4H2Br2S The article mentions the following:

Random polythiophene polymers are characterized by the arbitrary sequence of monomeric units along polymer backbones. These untailored orientations generally results in the twisting of thiophene rings out of the conjugation planarity in addition to steric repulsions experienced among substituted alkyl chains. These tendencies have limited close polymer packing which has been detrimental to charge transport in these moieties. To ameliorate charge transport in these class of polymers, we make use of simple Stille coupling polymerization to synthesize highly random polythiophene polymers. We induced a pos. microstructural change between polymer chains by attuning the ratio between alkyl substituted and non-alkyl substituted monomer units along the backbones. The optimized random polythiophene was found to have enhanced intermol. interaction, increased size of crystallites, and stronger tendency to take edge-orientation compared to both regiorandom and regioregular poly(3-hexylthiophene) polymers. Incorporation of the optimized random polythiophene as an active material in a solid-state electrolyte gate insulator-gated organic field-effect transistors exhibited better performance than control device using regioregular poly(3-hexylthiophene), with a high hole mobility up to 4.52 cm2 V-1 s-1 in ambient condition. The results came from multiple reactions, including the reaction of 2,5-Dibromothiophene(cas: 3141-27-3COA of Formula: C4H2Br2S)

2,5-Dibromothiophene(cas: 3141-27-3) , is mainly used as pharmaceutical intermediate and synthesis intermediate. 2,5-Dibromothiophene may be used in the preparation of soluble α,ω-diformyl-a-oligothiophenes.COA of Formula: C4H2Br2S

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

SDS of cas: 3141-27-3In 2022 ,《Silver salt enabled H/D exchange at the β-position of thiophene rings: synthesis of fully deuterated thiophene derivatives》 was published in Organic & Biomolecular Chemistry. The article was written by Sheng, Fei-Fei; Li, En-Ci; Bai, Jing-Wen; Wang, Cai-Xia; Hu, Guang-Qi; Liu, Kai-Hui; Sun, Zheng-Yi; Shen, Kang; Zhang, Hong-Hai. The article contains the following contents:

We disclose a silver catalyzed H/D exchange reaction, which can introduce the deuterium atom at the β position of thiophene rings without the assistance of any coordinating groups. The advantages of this reaction include operation in open air, usage of D2O as the deuterium source, good tolerance to a range of functional groups and obtaining high atom% deuterium incorporation. In addition, this H/D exchange reaction is employed for direct deuteration of a thiophene based monomer, which is usually prepared by multistep synthesis from expensive deuterated starting materials. In addition to this study using 2,5-Dibromothiophene, there are many other studies that have used 2,5-Dibromothiophene(cas: 3141-27-3SDS of cas: 3141-27-3) was used in this study.

2,5-Dibromothiophene(cas: 3141-27-3) , is mainly used as pharmaceutical intermediate and synthesis intermediate. 2,5-Dibromothiophene polymerizes by debromination with magnesium catalyzed by nickel compounds to form poly(2,5- thienylene) .SDS of cas: 3141-27-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Rech, Jeromy James; Yan, Liang; Wang, Zhen; Zhang, Qianqian; Bradshaw, Spencer; Ade, Harald; You, Wei published their research in ACS Applied Polymer Materials in 2021. The article was titled 《Functionalization of Benzotriazole-Based Conjugated Polymers for Solar Cells: Heteroatom vs Substituents》.Synthetic Route of C4H2Br2S The article contains the following contents:

With the recent remarkable advances in the efficiency of organic solar cells, the need to distill key structure-property relationships for semiconducting materials cannot be understated. The fundamental design criteria based on these structure-property relationships will help realize low-cost, scalable, and high-efficiency materials. In this study, we systematically explore the impact of a variety of functional groups, including nitrogen heteroatoms, fluorine substituents, and cyano groups, on benzotriazole (TAZ)-based acceptor moieties that are incorporated into the conjugated polymers. Specifically, a pyridine heterocycle was used to replace the benzene unit of TAZ, leading to the PyTAZ polymer, and a cyano substituent was added to the benzene of the TAZ unit, resulting in the CNTAZ polymer. The PyTAZ polymer suffers from low mobility and poor exciton harvesting, driven by large and excessively pure domains when blended with PCBM. The inclusion of fluorine substituents, placed strategically along the polymer backbone, can mitigate these issues, as shown with 4FT-PyTAZ. However, when this same approach is used for the cyano-functionalized polymer (CNTAZ), the resulting polymer (4FT-CNTAZ) is overfunctionalized and suffers from impure domains and recombination issues. The cyano group has a larger impact on the TAZ core compared to the nitrogen heteroatom due to the strong electron-withdrawing strength of the cyano group. Because of this, further functionalization of the cyano-based polymers has less fruitful impact on the polymer properties and results in deterioration of the solar cell efficiency. Overall, this work highlights some of the benefits, thresholds, and limitations for functionalization of conjugated polymers for organic solar cells. In the experimental materials used by the author, we found 2,5-Dibromothiophene(cas: 3141-27-3Synthetic Route of C4H2Br2S)

2,5-Dibromothiophene(cas: 3141-27-3) , is mainly used as pharmaceutical intermediate and synthesis intermediate. 2,5-Dibromothiophene may be used in the preparation of soluble α,ω-diformyl-a-oligothiophenes.Synthetic Route of C4H2Br2S

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Computed Properties of C4H2Br2SIn 2021 ,《Steering Scholl Oxidative Heterocoupling by Tuning Topology and Electronics for Building Thiananographenes and Their Functional N-/C-Congeners》 was published in Chemistry – A European Journal. The article was written by Maddala, Sudhakar; Panua, Anirban; Venkatakrishnan, Parthasarathy. The article contains the following contents:

This report systematically demonstrates how topol. variation of electronics and reactivity in thiophene substrates can lead to efficient oxidative heterocoupling. Bis(biaryl)thiophenes having reactive α- and β-positions open are the choice of substrates. The cyclizing arene partners are so electronically tuned for thiophene’s reactivity (at α- and β-) as to establish C-C bond oxidatively generating sym. as well as unsym. diphenanthrothiophenes which are basic thiananographenes. Depending on the cyclizing-couple’s electronics, either arene- or thiophene-centered oxidation initiates C-C heterocoupling. The potential utility of these simple thiananographenes is further unfurled by converting them to functional N-/C-graphene segments that are aza-corannulene precursor and tetrabenzospirobifluorene. Their bright emission and extended electrochem. stability are remarkable that may be potentially important and applicable. The results came from multiple reactions, including the reaction of 2,5-Dibromothiophene(cas: 3141-27-3Computed Properties of C4H2Br2S)

2,5-Dibromothiophene(cas: 3141-27-3) , is mainly used as pharmaceutical intermediate and synthesis intermediate. 2,5-Dibromothiophene polymerizes by debromination with magnesium catalyzed by nickel compounds to form poly(2,5- thienylene) .Computed Properties of C4H2Br2S

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2022,Liu, Yuxiang; Wu, Jun; Wang, Feng published an article in Applied Catalysis, B: Environmental. The title of the article was 《Dibenzothiophene-S,S-dioxide-containing conjugated polymer with hydrogen evolution rate up to 147 mmol g-1 h-1》.HPLC of Formula: 3141-27-3 The author mentioned the following in the article:

Mol. engineering in donor-acceptor conjugated polymers is currently one of the most successful and popular strategy to prepare high performance photocatalysts for hydrogen evolution. In this contribution, we have designed and synthesized two novel conjugated polymers with tailored donor-acceptor structures based on dibenzothiophene-S,S-dioxide and thiophene derivatives, which exhibited tunable band gaps and adjustable charge separation efficiencies. As a result, PDBTSO-T showed an outstanding hydrogen evolution rate (HER) of 1.47 mmol h-1 by DMF exfoliation under UV-vis region with Pt cocatalyst in ascorbic acid aqueous solution at 10 mg level, which is among the top performance for photocatalysis conversion reported so far. Very excitingly, when the photocatalysis tests were subjected to natural sunlight irradiation, an impressive HER of ∼27 mL (107 mmol g-1 h-1) was achieved after 0.5 h of illumination (12:30 pm – 13:00 pm) on a consistently sunny day under identical reaction conditions. The experimental process involved the reaction of 2,5-Dibromothiophene(cas: 3141-27-3HPLC of Formula: 3141-27-3)

2,5-Dibromothiophene(cas: 3141-27-3) , is mainly used as pharmaceutical intermediate and synthesis intermediate. 2,5-Dibromothiophene may be used in the preparation of soluble α,ω-diformyl-a-oligothiophenes.HPLC of Formula: 3141-27-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary