Category: 3141-27-3

Klingstedt, Therese; Shirani, Hamid; Ghetti, Bernardino; Vidal, Ruben; R. Nilsson, K. Peter published their research in ChemBioChem in 2021. The article was titled 《Thiophene-Based Optical Ligands That Selectively Detect Aβ Pathology in Alzheimer′s Disease》.Synthetic Route of C4H2Br2S The article contains the following contents:

In several neurodegenerative diseases, the presence of aggregates of specific proteins in the brain is a significant pathol. hallmark; thus, developing ligands able to bind to the aggregated proteins is essential for any effort related to imaging and therapeutics. Here we report the synthesis of thiophene-based ligands containing nitrogen heterocycles. The ligands selectively recognized amyloid-β (Aβ) aggregates in brain tissue from individuals diagnosed neuropathol. as having Alzheimer′s disease (AD). The selectivity for Aβ was dependent on the position of nitrogen in the heterocyclic compounds, and the ability to bind Aβ was shown to be reduced when introducing anionic substituents on the thiophene backbone. Our findings provide the structural and functional basis for the development of ligands that can differentiate between aggregated proteinaceous species comprised of distinct proteins. These ligands might also be powerful tools for studying the pathogenesis of Aβ aggregation and for designing mols. for imaging of Aβ pathol. In the experimental materials used by the author, we found 2,5-Dibromothiophene(cas: 3141-27-3Synthetic Route of C4H2Br2S)

2,5-Dibromothiophene(cas: 3141-27-3) , is mainly used as pharmaceutical intermediate and synthesis intermediate. 2,5-Dibromothiophene may be used in the preparation of soluble α,ω-diformyl-a-oligothiophenes.Synthetic Route of C4H2Br2S

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2022,Tavella, Christian; Luciano, Giorgio; Lova, Paola; Patrini, Maddalena; D’Arrigo, Cristina; Comoretto, Davide; Stagnaro, Paola published an article in RSC Advances. The title of the article was 《2,5-Diisopropenylthiophene by Suzuki-Miyaura cross-coupling reaction and its exploitation in inverse vulcanization: a case study》.Application of 3141-27-3 The author mentioned the following in the article:

A novel thiophene derivative, namely 2,5-diisopropenylthiophene (DIT) was synthesized by Suzuki-Miyaura cross-coupling reaction (SMCCR). The influence of reaction parameters, such as temperature, solvent, stoichiometry of reagents, role of the base and reaction medium were thoroughly discussed in view of yield optimization and environmental impact minimization. Basic design of experiment (DoE) and multiple linear regression (MLR) modeling methods were used to interpret the obtained results. DIT was employed as a comonomer in the copolymerization with waste elemental sulfur through a green process, inverse vulcanization (IV), to obtain sulfur-rich polymers named inverse vulcanized polymers (IVPs) possessing high refractive index (n 1̃.8). The DIT comonomer was purposely designed to (i) favor the IV process owing to the high reactivity of the isopropenyl functionalities and (ii) enhance the refractive index of the ensuing IVPs owing to the presence of the sulfur atom itself and to the high electronic polarizability of the π-conjugated thiophene ring. A series of random sulfur-r-diisopropenylthiophene (S-r-DIT) copolymers with sulfur content from 50-90 weight% were synthesized by varying the S/DIT feed ratio. Spectroscopic, thermal and optical characterizations of the new IVPs were carried out to assess their main chem.-phys. features. In addition to this study using 2,5-Dibromothiophene, there are many other studies that have used 2,5-Dibromothiophene(cas: 3141-27-3Application of 3141-27-3) was used in this study.

2,5-Dibromothiophene(cas: 3141-27-3) , is mainly used as pharmaceutical intermediate and synthesis intermediate. 2,5-Dibromothiophene may be used in the preparation of soluble α,ω-diformyl-a-oligothiophenes.Application of 3141-27-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Related Products of 3141-27-3In 2022 ,《Stable room temperature ferroelectricity in hydrogen-bonded supramolecular assemblies of ambipolar π-systems》 was published in Chemical Science. The article was written by Mukherjee, Anurag; Barman, Shubhankar; Ghosh, Anupam; Chakraborty, Saptarshi; Datta, Ayan; Datta, Anuja; Ghosh, Suhrit. The article contains the following contents:

This article reports H-bonding driven supramol. polymerization of naphthalimide (A)-thiophene (D)-naphthalimide (A) (ADnA, n = 1-4) conjugated ambipolar π-systems and its remarkable impact on room temperature ferroelectricity. Electrochem. studies confirm the ambipolar nature of these ADnA mols. with the HOMO-LUMO gap varying between 2.05 and 2.29 eV. Electron d. mapping from ESP calculations reveals intra-mol. charge separation as typically observed in ambipolar systems. In the aggregated state, AD1A and AD2A exhibit bathochromically shifted absorption bands while AD3A and AD4A show typical H-aggregation with a hypsochromic shift. Polarization vs. elec. field (P-E) measurements reveal stable room temperature ferroelectricity for these supramol. assemblies, most prominent for the AD2A system, with a Curie temperature (Tc) ∼ 361 K and saturation polarization (Ps) of ∼2μC cm-2 at a rather low coercive field of ∼2 kV cm-1. Control mols., lacking either the ambipolar chromophore or the amide functionality, do not show any ferroelectricity, vindicating the present mol. and supramol. design. Computational studies enable structural optimization of the stacked oligomer(s) of AD2A mols. and reveal a significant increase in the macro-dipole moment (in the range of 10-12 Debye) going from the monomer to the oligomer(s), which provides the rationale for the origin of ferroelectricity in these supramol. polymers. In the experimental materials used by the author, we found 2,5-Dibromothiophene(cas: 3141-27-3Related Products of 3141-27-3)

2,5-Dibromothiophene(cas: 3141-27-3) , is mainly used as pharmaceutical intermediate and synthesis intermediate. 2,5-Dibromothiophene polymerizes by debromination with magnesium catalyzed by nickel compounds to form poly(2,5- thienylene) .Related Products of 3141-27-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Synthesis of π-extended B←N coordinated phenanthroimidazole dimers and their linear and nonlinear optical properties》 was written by Vanga, Mukundam; Sa, Shreenibasa; Kumari, Anupa; Murali, Anna Chandrasekar; Nayak, Prakash; Das, Ritwick; Venkatasubbaiah, Krishnan. Product Details of 3141-27-3 And the article was included in Dalton Transactions in 2020. The article conveys some information:

Intramol. B←N coordinated fluorophores have shown potential applications in optoelectronics and as sensors due to their unique photophys. properties. In this work, we report the synthesis and characterization of π-conjugated boron doped phenanthroimidazole dimers I [7-11, R = H, C6H13; X = bond, 2,5-(C6H13O)2C6H3, 2,5-thiophenediyl, 9,9-(C6H14)2-2,7-fluorenediyl, 9-C6H14-2,7-carbazolediyl]. The synthesis starts from 1-(4-RC6H4)-2-(4-BrC6H4)-1H-phenanthro[9,10-d]imidazole via BBr3 borylation, methylation of the boron center, boronation and Suzuki coupling with dibromides BrXBr. All the π-conjugated B←N coordinated phenanthroimidazole dimers exhibited high quantum yields in solution (up to 99%) and moderate quantum yields in the solid state (up to 51%). We investigated the nonlinear optical properties of phenanthroimidazole dimers and found that the measurement of two-photon-absorption cross-section is correlated with the conjugation length. In the experimental materials used by the author, we found 2,5-Dibromothiophene(cas: 3141-27-3Product Details of 3141-27-3)

2,5-Dibromothiophene(cas: 3141-27-3) , is mainly used as pharmaceutical intermediate and synthesis intermediate. 2,5-Dibromothiophene polymerizes by debromination with magnesium catalyzed by nickel compounds to form poly(2,5- thienylene) .Product Details of 3141-27-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Pu, Mingrui; Chen, Hui; Chao, Pengjie; Zhu, Yulin; Zheng, Nan; Lai, Hanjian; Zhao, Tingxing; He, Feng published their research in ACS Applied Polymer Materials in 2021. The article was titled 《Chlorinated Random Terpolymers with Efficient Solar Conversion and Low Batch-to-Batch Variation》.Electric Literature of C4H2Br2S The article contains the following contents:

The strategy of random terpolymn. has been shown to be a flexible and effective method with which to construct state-of-the-art polymer donors, and chlorination has frequently been utilized to fine-tune material properties in these polymers with the aim of improving the solar conversion efficiency. Herein, three random terpolymers consisting of BDT, BDD, and Th-Cl monomers in the optimized ratio of 1:0.85:0.15 were synthesized in parallel in an effort to understand the effect of chlorination in terpolymer systems and the chlorine-containing derviatives (named PBDB-Th15, PBDB-ThCl15, and PBDB-Th2Cl15). Among these three polymers, PBDB-ThCl15 shows a low-lying HOMO level, the most balanced hole and electron mobility, and enhanced aggregation behavior in blend film as a result of the introduction of one chlorine atom. When blended with a small mol. acceptor Y6, the resulting PBDB-ThCl15:Y6-based device showed the highest PCE of 15.63% of the three polymers. The PBDB-Th15- and PBDB-Th2Cl15-based devices present relatively poor conversion efficiencies of 14.91% and 12.62%. Interestingly, the terpolymer PBDB-ThCl15 was repeatedly prepared by random terpolymn. under the same conditions, and a low batch-to-batch variation was observed with a PCE of 1̃5.50%. These results indicate that the synergy of chlorination with random terpolymn. promises to contribute to the preparation of stable and high-performance solar cell polymers. In the experimental materials used by the author, we found 2,5-Dibromothiophene(cas: 3141-27-3Electric Literature of C4H2Br2S)

2,5-Dibromothiophene(cas: 3141-27-3) , is mainly used as pharmaceutical intermediate and synthesis intermediate. 2,5-Dibromothiophene may be used in the preparation of soluble α,ω-diformyl-a-oligothiophenes.Electric Literature of C4H2Br2S

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Zhang, Liyan; Jin, Tengda; Guo, Yingjie; Martin, A. C.; Sun, Keju; Dudley, Gregory B.; Yang, Jingyue published an article in 2021. The article was titled 《Synthesis of gem-Dimethylcyclopentane-Fused Arenes with Various Topologies via TBD-Mediated Dehydro-Diels-Alder Reaction》, and you may find the article in Journal of Organic Chemistry.Reference of 2,5-Dibromothiophene The information in the text is summarized as follows:

The development of efficient methods for the synthesis of substituted polycyclic arenes with various topologies is in high demand due to their excellent elec. and optical properties. In this work, a series of gem-dimethylcyclopentane-fused arenes with more than ten topologies were synthesized via a 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD)-mediated dehydro-Diels-Alder reaction with moderate to good yields. The introduction of the near-planar gem-dimethylcyclopentane moiety not only impacts the mol. conjugative system but also regulates the intermol. π-π interactions and crystal packing, which are critical for the photoelec. performance of arenes. The photophys. properties, mol. geometry, mol. packing of these compounds, and electrochem. properties were investigated by UV-vis absorption, fluorescence emission spectra, DFT calculations, single-crystal X-ray structure anal., and cyclic voltammetry study. In the experimental materials used by the author, we found 2,5-Dibromothiophene(cas: 3141-27-3Reference of 2,5-Dibromothiophene)

2,5-Dibromothiophene(cas: 3141-27-3) , is mainly used as pharmaceutical intermediate and synthesis intermediate. 2,5-Dibromothiophene may be used as starting reagent for the synthesis of α,α′-didecylquater-, -quinque- and -sexi-thiophenes.Reference of 2,5-Dibromothiophene

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Cross-coupling polymerization at iodophenyl thin films prepared by spontaneous grafting of a diazonium salt》 was published in PeerJ Materials Science in 2020. These research results belong to Marshall, Nicholas; Rodriguez, Andres. Product Details of 3141-27-3 The article mentions the following:

Cross-coupling at aryl halide thin films has been well-established as a technique for the surface-initiated Kumada catalyst transfer polymerization (SI-KCTP), used to produce covalently bound conjugated polymer thin films. In this work, we report that the spontaneous grafting of 4-iodobenzenediazonium tetrafluoroborate on gold substrates creates a durable iodoarene layer which is effective as a substrate for cross-coupling reactions including SI-KCTP. Using cyclic voltammetry of a surface-coupled ferrocene terminating agent, we have measured initiator surface coverage produced by oxidative addition of Pd(t-Bu3P)2 and estimated the rate constant of the termination reaction in the SI-KCTP system with 2-chloromagnesio-5-bromothiophene and Pd(t-Bu3P)2. We used this system to prepare uniform polythiophene thin films averaging 90 nm in thickness. In addition to this study using 2,5-Dibromothiophene, there are many other studies that have used 2,5-Dibromothiophene(cas: 3141-27-3Product Details of 3141-27-3) was used in this study.

2,5-Dibromothiophene(cas: 3141-27-3) , is mainly used as pharmaceutical intermediate and synthesis intermediate. 2,5-Dibromothiophene may be used in the preparation of soluble α,ω-diformyl-a-oligothiophenes.Product Details of 3141-27-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Click-based conjugated microporous polymers as efficient heterogeneous photocatalysts for organic transformations》 was written by Gan, Shaolin; Zeng, Yan; Liu, Jiaxin; Nie, Junqi; Lu, Cuifen; Ma, Chao; Wang, Feiyi; Yang, Guichun. Synthetic Route of C4H2Br2SThis research focused ontriazole thiophene conjugated polymer catalyst preparation optical band gap; dimethylaniline aryl iso isocyanide triazolethiophene catalyst ugi reaction; methyl arylamino phenylacetanmide preparation; tetrahydroisoquinoline triazolethiophene catalyst oxidation; tetrahydroisoquinolinone preparation. The article conveys some information:

In this study, the design and synthesis of three 1,2,3-triazole-thiophene based CMP (Ta-Th) photocatalysts through the click reaction was described. Compared with the corresponding thienyl- and bithienyl-bridged Ta-Th-4 and Ta-Th-5, the terthiophene based Ta-Th-6 shows a stronger light-harvesting ability, a narrower optical energy gap, and a better charge separation efficiency for facilitated charge transfer, which make Ta-Th-6 a promising candidate for photoredox reactions. Indeed, Ta-Th-6 presents superior photocatalytic activity in the Ugi multicomponent reaction and α-oxidation of N-substituted tetrahydroisoquinolines. Furthermore, the catalyst exhibits a considerable activity after recycling five times, demonstrating its high stability and excellent reusability. The experimental part of the paper was very detailed, including the reaction process of 2,5-Dibromothiophene(cas: 3141-27-3Synthetic Route of C4H2Br2S)

2,5-Dibromothiophene(cas: 3141-27-3) , is mainly used as pharmaceutical intermediate and synthesis intermediate. 2,5-Dibromothiophene polymerizes by debromination with magnesium catalyzed by nickel compounds to form poly(2,5- thienylene) .Synthetic Route of C4H2Br2S

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Narayanan, Sona; Sreekumar, K.; Joseph, Rani published an article in 2021. The article was titled 《Synthesis and third-order nonlinear optical properties of low band gap 3,4-ethylenedioxythiophene-thiophene copolymers》, and you may find the article in Materials Today: Proceedings.Category: bromides-buliding-blocks The information in the text is summarized as follows:

Alternate donor-acceptor 3,4-ethylenedioxythiophene (EDOT) based copolymers with thiophene and 3-Me thiophene were designed by employing d. functional theory (DFT) in the periodic boundary condition using HSE06 exchange correlation functional and 6-31G basis set. The designed copolymers were synthesized via a simple and facile route, i.e., direct arylation and their third-order nonlinear optical properties were investigated by Z-scan technique. The resultant copolymers, P(EDOT-THP) and P(EDOT-MeTHP) were characterized by spectroscopic anal. The photophys. and electrochem. properties of EDOT-thiophene copolymers were investigated by UV-visible spectra and cyclic voltammetry, resp. The copolymers revealed low band gap and better electronic properties as compared to the homopolymers. The introduction of EDOT unit in the polythiophene leads to decreased HOMO-LUMO energy levels, and the absorption spectra was red shifted when compared with that of the parent compound The nonlinear absorption and nonlinear refraction coefficient of copolymers have been investigated at 532 nm. The optical limiting properties of copolymers have also been measured. The copolymers exhibited strong optical nonlinearity owing to the presence of alternate donor-π-acceptor scheme in the polymers. The results came from multiple reactions, including the reaction of 2,5-Dibromothiophene(cas: 3141-27-3Category: bromides-buliding-blocks)

2,5-Dibromothiophene(cas: 3141-27-3) , is mainly used as pharmaceutical intermediate and synthesis intermediate. 2,5-Dibromothiophene may be used as starting reagent for the synthesis of α,α′-didecylquater-, -quinque- and -sexi-thiophenes.Category: bromides-buliding-blocks

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《A Bithiophene-Promoted ppm Levels of Palladium-Catalyzed Regioselective Hydrosilylation of Terminal Allenes》 was published in Advanced Synthesis & Catalysis in 2020. These research results belong to Chen, Jun-Jia; Zeng, Jia-Hao; Yang, Ying; Liu, Zhi-Kai; Jiang, Ya-Nan; Li, Miao-Ran; Chen, Li; Zhan, Zhuang-Ping. Computed Properties of C4H2Br2S The article mentions the following:

A bithiophene-alkyne-based compound was synthesized and 1st used as a ligand for the selective hydrosilylation of allenes with primary and secondary phenylsilanes. It shows high selectivity towards the production of branched allylsilanes with a wide range of allenes. It is worth mentioning that the catalytic loading of the Pd can be reduced to 500 ppm. This work opens a new front of using bidentate thiophene ligand as a reaction promoter in transition-metal-catalyzed organic reaction. The experimental process involved the reaction of 2,5-Dibromothiophene(cas: 3141-27-3Computed Properties of C4H2Br2S)

2,5-Dibromothiophene(cas: 3141-27-3) , is mainly used as pharmaceutical intermediate and synthesis intermediate. 2,5-Dibromothiophene may be used in the preparation of soluble α,ω-diformyl-a-oligothiophenes.Computed Properties of C4H2Br2S

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary