Category: 30752-31-9

Formula: C12H15BrOOn May 2, 2005 ,《Copper-catalyzed etherification of aryl iodides using KF/Al2O3. An improved protocol》 appeared in Synlett. The author of the article were Hosseinzadeh, Rahman; Tajbakhsh, Mahmood; Mohadjerani, Maryam; Alikarami, Mohammad. The article conveys some information:

A simple and efficient method for the coupling of aryl iodides with aliphatic alcs. and phenols that does not require the use of alkoxide bases is described. This C-O bond forming procedure shows that the combination of air stable CuI and 1,10-phenanthroline in the presence of KF/Al2O3 comprises an extremely efficient and general catalyst system for the etherification of aryl iodides. Different functionalized aryl iodides were coupled with alcs. and phenols using this method. In the experimental materials used by the author, we found 1-Bromo-4-(cyclohexyloxy)benzene(cas: 30752-31-9Formula: C12H15BrO)

1-Bromo-4-(cyclohexyloxy)benzene(cas: 30752-31-9) belongs to organobromine compounds.Organobromine chemicals are produced naturally by an array of biological and other chemical processes in our environment. Formula: C12H15BrOSome of these compounds are identical to man-made organobromine compounds, such as methyl bromide, bromoform, and bromophenols, but many others are entirely new moleclar entities, often possessing extraordinary and important biological properties.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Decarboxylative C(sp3)-O Cross-Coupling》 was published in Angewandte Chemie, International Edition in 2018. These research results belong to Mao, Runze; Balon, Jonathan; Hu, Xile. Application of 30752-31-9 The article mentions the following:

Alkyl aryl ethers are an important class of compounds in medicinal and agricultural chem. Catalytic C(sp3)-O cross-coupling of alkyl electrophiles with phenols is an unexplored disconnection strategy to the synthesis of alkyl aryl ethers, with the potential to overcome some of the major limitations of existing methods such as C(sp2)-O cross-coupling and SN2 reactions. Reported here is a tandem photoredox and copper catalysis to achieve decarboxylative C(sp3)-O coupling of alkyl N-hydroxyphthalimide (NHPI) esters with phenols under mild reaction conditions. This method was used to synthesize a diverse set of alkyl aryl ethers using readily available alkyl carboxylic acids, including many natural products and drug mols. Complementarity in scope and functional-group tolerance to existing methods was demonstrated. In the experimental materials used by the author, we found 1-Bromo-4-(cyclohexyloxy)benzene(cas: 30752-31-9Application of 30752-31-9)

1-Bromo-4-(cyclohexyloxy)benzene(cas: 30752-31-9) belongs to organobromine compounds.The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. Application of 30752-31-9 The principal reactions for organobromides include dehydrobromination, Grignard reactions, reductive coupling, and nucleophilic substitution.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

The author of 《Kaolin-assisted Aromatic Chlorination and Bromination》 were Hirano, Masao; Monobe, Hiroyuki; Yakabe, Shigetaka; Morimoto, Takashi. And the article was published in Journal of Chemical Research, Synopses in 1998. HPLC of Formula: 30752-31-9 The author mentioned the following in the article:

Moist kaolin catalyzes the regioselective and high-yielding chlorination and bromination of C6H5OR (R = C1-C8 alkyl, But, allyl, cyclohexyl, benzyl) to 4-XC6H4OR (X = Cl and Br, resp.) with NaClO2 and Mn(acac)3 in CH2Cl2 in the absence and presence of NaBr, resp., under mild and neutral conditions. After reading the article, we found that the author used 1-Bromo-4-(cyclohexyloxy)benzene(cas: 30752-31-9HPLC of Formula: 30752-31-9)

1-Bromo-4-(cyclohexyloxy)benzene(cas: 30752-31-9) belongs to organobromine compounds.The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. The principal reactions for organobromides include dehydrobromination, Grignard reactions, reductive coupling, and nucleophilic substitution.HPLC of Formula: 30752-31-9

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Usutani, Hirotsugu; Cork, David G. published an article in Organic Process Research & Development. The title of the article was 《Effective Utilization of Flow Chemistry: Use of Unstable Intermediates, Inhibition of Side Reactions, and Scale-Up for Boronic Acid Synthesis》.Formula: C12H15BrO The author mentioned the following in the article:

Flow chem. processes for boronic acid syntheses utilizing lithiation-borylation have been developed. The side reactions in the lithiation step that occur in batch were suppressed, and unstable lithium intermediates were handled safely. Flow technol. was applied to several kinds of boronic acid syntheses, and scale-up was successfully conducted to allow kilogram-scale production Some of the key benefits of flow flash chem. were utilized, both to avoid side reactions and to enable dianion chem. that is difficult to perform successfully in batch reactions. The examples showed further perspectives on the utility of flow technologies for process development. In the experimental materials used by the author, we found 1-Bromo-4-(cyclohexyloxy)benzene(cas: 30752-31-9Formula: C12H15BrO)

1-Bromo-4-(cyclohexyloxy)benzene(cas: 30752-31-9) belongs to organobromine compounds.Most of the natural organobromine compounds are produced by marine organisms , and several brominated metabolites with antibacterial , antitumor , antiviral , and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. Formula: C12H15BrO In contrast, terrestrial plants account only for a few bromine-containing compounds.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《A simple regioselective nuclear bromination of alkyl phenyl ethers》 was written by Yakabe, Shigetaka; Hirano, Masao; Morimoto, Takashi. SDS of cas: 30752-31-9 And the article was included in Organic Preparations and Procedures International on April 30 ,1998. The article conveys some information:

The regioselective bromination of alkyl Ph ethers was carried out with sodium perchlorate/sodium bromide/tris(acetylacetonato)manganese/moist alumina. In the experimental materials used by the author, we found 1-Bromo-4-(cyclohexyloxy)benzene(cas: 30752-31-9SDS of cas: 30752-31-9)

1-Bromo-4-(cyclohexyloxy)benzene(cas: 30752-31-9) belongs to organobromine compounds.Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. SDS of cas: 30752-31-9 Alkyl bromides are mainly used as alkylating agents and also find application as a solvent to extract oil from seeds and wool.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary