Category: 30432-16-7

Some common heterocyclic compound, 30432-16-7, name is 1,4-Dibromo-2,3-bis(bromomethyl)but-2-ene, molecular formula is C6H8Br4, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. Product Details of 30432-16-7

General procedure: Alkyl 4-hydroxy benzoate 2a,b (10 mmol) and potassium hydroxide (0.56 g, 10 mmol) were dissolved in absolute ethanol. 1,1,2,2-tetrayl-tetramethylene-tetrabromide (1) (1.00 g, 2.5 mmol) was then added into this solution. The reaction mixture was refluxed for 6 h. The mixture was cooled and filtrated. The white precipitate was filtered off and washed with H2O and crystallized from the appropriate solvent.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 30432-16-7, its application will become more common.

Reference:
Article; Er, Mustafa; De?irmencio?lu, Ismail; Tahtaci, Hakan; Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy; vol. 139; 1; (2015); p. 68 – 74;,
Bromide – Wikipedia,
bromide – Wiktionary

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 30432-16-7, name is 1,4-Dibromo-2,3-bis(bromomethyl)but-2-ene, This compound has unique chemical properties. The synthetic route is as follows., HPLC of Formula: C6H8Br4

4-Hydroxy benzonitrile (3) (1.19 g, 10 mmol) and potassium hydroxide (0.56 g, 10 mmol) were dissolved in absolute ethanol. 1,1,2,2-tetrayl-tetramethylene-tetrabromide (1) (1.00 g, 2.5 mmol) was then added into this solution. The reaction mixture was refluxed for 8 h. The solution was cooled and filtrated. The white solid obtained was washed with H2O, alcohol and crystallized from DMF. Yield: 1.14 g (83%). mp 212-214 C. IR (ATR, cm-1): 3080 nu(=CH), 2949 nu(-CH2), 2222 nu(C?N), 1601 nu(C=C), 1573, 1504 nu(C-C), 1298, 1236, 1113 nu(C-O-C), 1086 nu(Ester C-O-C),833 nu(1,4-disubst.), 695 deltar(CH2). 1H NMR (400 MHz, DMSO-d6, delta ppm): 4.94 (s, 8H, O-CH2), 7.08 (d, AA’ , 8H, J = 16.0 Hz, Ar-H), 7.72 (d, AA’ , 8H, J = 16.0 Hz, Ar-H). 13C NMR (100 MHz, DMSOd6, delta ppm): 65.55 (O-CH2), Ar-C: [103.60 (C), 116.26 (CH),134.53 (CH), 162.06 (C)], 135.50 (C=C); 119.52 (C?N). Analysis (% calculated/found) for C34H24N4O4 (Mw 552.58) C: 73.90/73.81;H: 4.38/4.44; N: 10.14/10.17. MS(ESI-m/z): 575.36 [M+Na]+.

According to the analysis of related databases, 30432-16-7, the application of this compound in the production field has become more and more popular.

Reference:
Article; Er, Mustafa; De?irmencio?lu, Ismail; Tahtaci, Hakan; Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy; vol. 139; 1; (2015); p. 68 – 74;,
Bromide – Wikipedia,
bromide – Wiktionary

Reference of 30432-16-7, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 30432-16-7, name is 1,4-Dibromo-2,3-bis(bromomethyl)but-2-ene belongs to bromides-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.

Dissolve p-toluenesulfonamide (39.4g, 0.23mol) and potassium carbonate (202g, 1.45mol) in N,N-dimethylformamide (400mL), add 1,4-dibromo-2,3-bis(bromomethyl)but-2-ene (40g, 0.10mol), react at room temperature for 24 hours. Water (100 mL) was added to quench the reaction, stirred for 10 minutes, filtered, the filter cake was slurried with ethyl acetate (50 mL), filtered, and the filter cake was collected and dried to give the title compound 9b (39 g, yield 93%) as a white solid.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1,4-Dibromo-2,3-bis(bromomethyl)but-2-ene, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; Guangdong Dongyangguang Pharmaceutical Co., Ltd.; Gu Zheng; Li Jianhao; Wang Weihua; Tan Haoxiong; Liu Jianyu; Zhang Yingjun; (73 pag.)CN111196806; (2020); A;,
Bromide – Wikipedia,
bromide – Wiktionary

Related Products of 30432-16-7,Some common heterocyclic compound, 30432-16-7, name is 1,4-Dibromo-2,3-bis(bromomethyl)but-2-ene, molecular formula is C6H8Br4, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

In a two-necked flask, 4-hydroxybenzaldehyde (1) (0.02 mol) and KOH (0.02 mol) were dissolved in absolute ethyl alcohol (100 mL) and the solution was stirred for 30 minutes at room temperature. 1,4-dibromo-2,3-bis(bromomethyl)but-2-ene (2) (0.005 mol) was dissolved in absolute ethanol (25 mL) and added drop-wise to this solution at room temperature with the assistance of a dropping funnel. The mixture was then refluxed and stirred for 10 h. After completion of the reaction, the solution was filtered and the solid matter was obtained. It was washed with deionized water, ethanol and diethyl ether, subsequently. The solid matter was recrystallized using DMF/EtOH (1:1). The synthesized compound was dried with P2O5 in a vacuum oven. Some physical properties, the yield and FT-IR data for compound (3) are given in Table 1 and Table 2.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 1,4-Dibromo-2,3-bis(bromomethyl)but-2-ene, its application will become more common.

Reference:
Article; Uysal, ?aban; Er, Mustafa; Tahtaci, Hakan; Synthetic Communications; vol. 46; 22; (2016); p. 1820 – 1832;,
Bromide – Wikipedia,
bromide – Wiktionary

Synthetic Route of 30432-16-7, These common heterocyclic compound, 30432-16-7, name is 1,4-Dibromo-2,3-bis(bromomethyl)but-2-ene, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.

General procedure: Alkyl 4-hydroxy benzoate 2a,b (10 mmol) and potassium hydroxide (0.56 g, 10 mmol) were dissolved in absolute ethanol. 1,1,2,2-tetrayl-tetramethylene-tetrabromide (1) (1.00 g, 2.5 mmol) was then added into this solution. The reaction mixture was refluxed for 6 h. The mixture was cooled and filtrated. The white precipitate was filtered off and washed with H2O and crystallized from the appropriate solvent.

The synthetic route of 30432-16-7 has been constantly updated, and we look forward to future research findings.

Reference:
Article; Er, Mustafa; De?irmencio?lu, Ismail; Tahtaci, Hakan; Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy; vol. 139; 1; (2015); p. 68 – 74;,
Bromide – Wikipedia,
bromide – Wiktionary