Category: 2635-13-4

Wang, Chengdong; Guo, Yingjie; Wang, Xiaoming; Wang, Zheng; Ding, Kuiling published their research in Chemistry – A European Journal in 2021. The article was titled 《Ni-Catalyzed Regioselective Hydroarylation of 1-Aryl-1,3-Butadienes with Aryl Halides》.Related Products of 2635-13-4 The article contains the following contents:

An efficient nickel-catalyzed regioselective hydroarylation of 1,3-dienes with aryl halides and a silane has been developed, affording a range of allylic arenes in good to excellent yields under mild conditions. This method exhibits broad substrate scope, and excellent functional group tolerance. Late-stage modification of complex architectures was demonstrated.5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4Related Products of 2635-13-4) was used in this study.

Furthermore, the coupling of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4) with β-methallyl alcohol was catalyzed by Pd(OAc)2 in combination with P(t-Bu)3.Related Products of 2635-13-4

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Sterman, Andrej; Kosmrlj, Janez; Zigart, Nina; Gobec, Stanislav; Sosic, Izidor; Casar, Zdenko published their research in Advanced Synthesis & Catalysis in 2021. The article was titled 《Catalytic Approach to Diverse α-Aminoboronic Acid Derivatives by Iridium-Catalyzed Hydrogenation of Trifluoroborate-Iminiums》.Safety of 5-Bromobenzo[d][1,3]dioxole The article contains the following contents:

Structurally diverse benzyl protected trifluoroborate-ammoniums were prepared in good to high yields by an efficient hydrogenation of corresponding trifluoroborate-iminiums using Crabtree’s catalyst. Subsequent N- and B-deprotections were demonstrated on selected examples to provide several α-aminoboronic acids. Preliminary experiments on asym. version of the reaction indicated a correlation between E/Z-ratio in the trifluoroborate-iminium substrate and enantioselectivity. The broad scope, operational simplicity and efficiency of the presented method imply its high potential for a facile access to libraries of α-aminoboronic acid derivatives that can be used in medicinal chem. applications and beyond. In addition to this study using 5-Bromobenzo[d][1,3]dioxole, there are many other studies that have used 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4Safety of 5-Bromobenzo[d][1,3]dioxole) was used in this study.

Furthermore, the coupling of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4) with β-methallyl alcohol was catalyzed by Pd(OAc)2 in combination with P(t-Bu)3.Safety of 5-Bromobenzo[d][1,3]dioxole

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Saikia, Rakhee; Park, Kwihwan; Masuda, Hayato; Itoh, Miki; Yamada, Tsuyoshi; Sajiki, Hironao; Mahanta, Sanjeev P.; Thakur, Ashim J.; Bora, Utpal published an article in 2021. The article was titled 《Revisiting the synthesis of aryl nitriles: a pivotal role of CAN》, and you may find the article in Organic & Biomolecular Chemistry.Synthetic Route of C7H5BrO2 The information in the text is summarized as follows:

Facilitated by the dual role of ceric ammonium nitrate (CAN), herein a cost-effective approach for the cyanation of aryl iodides/bromides with CAN-DMF as an addition to the existing pool of combined cyanation sources was reported. In addition to being an oxidant, CAN acted as a source of nitrogen in our protocol. The reaction was catalyzed by a readily available Cu(II) salt and the ability of CAN to generate ammonia in the reaction medium was utilized to eliminate the addnl. requirement of a nitrogen source, ligand, additive or toxic reagents. The mechanistic study suggested an evolution of CN- leading to the synthesis of a variety of aryl nitriles ArCN [Ar = Ph, 4-OHC6H4, 4-H2NC6H4, etc.] in moderate to good yields. The proposed mechanism was supported by a series of control reactions and labeling experiments After reading the article, we found that the author used 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4Synthetic Route of C7H5BrO2)

Furthermore, the coupling of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4) with β-methallyl alcohol was catalyzed by Pd(OAc)2 in combination with P(t-Bu)3.Synthetic Route of C7H5BrO2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2022,Zhu, Jin; Wang, Yidong; Charlack, Aaron D.; Wang, Yi-Ming published an article in Journal of the American Chemical Society. The title of the article was 《Enantioselective and Diastereodivergent Allylation of Propargylic C-H Bonds》.Product Details of 2635-13-4 The author mentioned the following in the article:

An iridium-catalyzed stereoselective coupling of allylic ethers and alkynes to generate 3,4-substituted 1,5-enynes was reported. Under optimized conditions, the coupling products were formed with excellent regio-, diastereo-, and enantioselectivities, and the protocol was functional group tolerant. Moreover, conditions that allowed the reaction to proceed with complete reversal of diastereoselectivity was reported. Mechanistic studies were consistent with an unprecedented dual role for the iridium catalyst, enabling the propargylic deprotonation of the alkyne through π-coordination, as well as the generation of a π-allyl species from the allylic ether starting material. The experimental part of the paper was very detailed, including the reaction process of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4Product Details of 2635-13-4)

Furthermore, the coupling of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4) with β-methallyl alcohol was catalyzed by Pd(OAc)2 in combination with P(t-Bu)3.Product Details of 2635-13-4

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《trans-Selective Aryldifluoroalkylation of Endocyclic Enecarbamates and Enamides by Nickel Catalysis》 was written by Xu, Chang; Cheng, Ran; Luo, Yun-Cheng; Wang, Ming-Kuan; Zhang, Xingang. Name: 5-Bromobenzo[d][1,3]dioxole And the article was included in Angewandte Chemie, International Edition in 2020. The article conveys some information:

Efficient methods for the dicarbofunctionalization of the cyclic alkenes 2-pyrroline and 2-azetine are limited. Particularly, the dicarbofunctionalization of endocyclic enecarbamates to achieve fluorinated compounds remains an unsolved issue. Reported here is a nickel-catalyzed trans-selective dicarbofunctionalization of N-Boc-2-pyrroline and N-Boc-2-azetine, a class of endocyclic enecarbamates previously unexplored for transition metal catalyzed dicarbofunctionalization. The reaction can be extended to six- and seven-membered endocyclic enamides. A variety of arylzinc reagents and bromodifluoroacetate, and its derivatives, undergo the reaction, providing straightforward and efficient access to an array of pyrrolidine- and azetidine-containing fluorinated amino acids and oligopeptides, which may have applications in the life sciences. The results came from multiple reactions, including the reaction of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4Name: 5-Bromobenzo[d][1,3]dioxole)

Furthermore, the coupling of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4) with β-methallyl alcohol was catalyzed by Pd(OAc)2 in combination with P(t-Bu)3.Name: 5-Bromobenzo[d][1,3]dioxole

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Catalytic Enantioselective Synthesis of anti-Vicinal Silylboronates by Conjunctive Cross-Coupling》 was written by Meng, Yan; Kong, Ziyin; Morken, James P.. Quality Control of 5-Bromobenzo[d][1,3]dioxole And the article was included in Angewandte Chemie, International Edition in 2020. The article conveys some information:

Chiral 1,2-bimetallic reagents are useful motifs in synthetic chem. Although syn-1,2-bimetallic compounds can be prepared by alkene dimetalation, anti-1,2-bimetallics are still rare. The stereospecific 1,2-metalate shift that occurs during conjunctive cross-coupling is shown to enable a practical and modular approach to the catalytic synthesis of enantioenriched anti-1,2-borosilanes. In addition to reaction development, the synthetic utility of anti-1,2-borosilanes was studied, including applications to the synthesis of anti-1,2-diols and anti-1,2-amino alcs. The experimental part of the paper was very detailed, including the reaction process of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4Quality Control of 5-Bromobenzo[d][1,3]dioxole)

Furthermore, the coupling of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4) with β-methallyl alcohol was catalyzed by Pd(OAc)2 in combination with P(t-Bu)3.Quality Control of 5-Bromobenzo[d][1,3]dioxole

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Waterford, Matthew; Saubern, Simon; Hornung, Christian H. published their research in Australian Journal of Chemistry in 2021. The article was titled 《Evaluation of a Continuous-Flow Photo-Bromination Using N-Bromosuccinimide for Use in Chemical Manufacture》.SDS of cas: 2635-13-4 The article contains the following contents:

A continuous-flow photo-bromination reaction on benzyl and Ph groups was conducted using N-bromosuccinimide as the bromine source inside a preparatory-scale glass plate reactor. This flow reactor system was capable of independently controlling light intensity, wavelength, and reaction temperature, hence exerting an exceptional level of control over the reaction. A short optimization study for the synthesis of 2-bromomethyl-4-trifluoromethoxyphenylboronic acid pinacol ester resulted in best conditions of 20° and 10 min residence time using an LED (light-emitting diode) array at 405 nm and acetonitrile as the solvent. The present study evaluates the potential for this easy-to-handle bromination system to be scaled up for chem. manufacture inside a continuous-flow glass plate reactor. The combination with an in-line continuous flow liquid-liquid extraction and separation system, using a membrane separator, demonstrates the potential for continuous flow reaction with purification in an integrated multi-stage operation with minimal manual handling in between. After reading the article, we found that the author used 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4SDS of cas: 2635-13-4)

Furthermore, the coupling of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4) with β-methallyl alcohol was catalyzed by Pd(OAc)2 in combination with P(t-Bu)3.SDS of cas: 2635-13-4

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Trifluoromethyl Sulfoxides: Reagents for Metal-Free C-H Trifluoromethylthiolation》 was published in Angewandte Chemie, International Edition in 2020. These research results belong to Wang, Dong; Carlton, C. Grace; Tayu, Masanori; McDouall, Joseph J. W.; Perry, Gregory J. P.; Procter, David J.. Recommanded Product: 5-Bromobenzo[d][1,3]dioxole The article mentions the following:

Indoles, pyrroles, thiophenes, a benzothiophene, a benzofuran, and arenes underwent metal-free regioselective trifluoromethylthiolation with trifluoromethyl sulfoxides RCH2S(:O)CF3 (R = Ph, EtO2C) mediated by triflic anhydride and diethylamine in acetonitrile or nitromethane to yield heteroaryl and aryl trifluoromethyl thioethers. An aryl(ethoxycarbonylmethyl)(trifluoromethyl)sulfonium triflate was isolated as a trifluoromethylthiolation intermediate and its structure determined by X-ray crystallog., supporting an interrupted Pummerer reaction mechanism for the trifluoromethylthiolation. In the experiment, the researchers used 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4Recommanded Product: 5-Bromobenzo[d][1,3]dioxole)

Furthermore, the coupling of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4) with β-methallyl alcohol was catalyzed by Pd(OAc)2 in combination with P(t-Bu)3.Recommanded Product: 5-Bromobenzo[d][1,3]dioxole

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Kim, Minjae; Park, Bohyun; Shin, Minkyeong; Kim, Suyeon; Kim, Junghoon; Baik, Mu-Hyun; Cho, Seung Hwan published their research in Journal of the American Chemical Society in 2021. The article was titled 《Copper-Catalyzed Enantiotopic-Group-Selective Allylation of gem-Diborylalkanes》.SDS of cas: 2635-13-4 The article contains the following contents:

The authors report a Cu-catalyzed enantiotopic-group-selective allylation of gem-diborylalkanes with allyl bromides. The combination of Cu(I) bromide and H8-BINOL derived phosphoramidite ligand proved to be the most effective catalytic system to provide various enantioenriched homoallylic boronate esters, containing a B-substituted stereogenic center that is solely derived from gem-diborylalkanes, in good yields with high enantiomeric ratios under mild conditions. Exptl. and theor. studies were conducted to elucidate the reaction mechanism, revealing how the enatiotopic-group-selective transmetalation of gem-diborylalkanes with chiral Cu complex occurs to generate chiral α-borylalkyl-Cu species for the 1st time. Addnl. synthetic applications to the synthesis of various chiral building blocks are also included. In the experiment, the researchers used 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4SDS of cas: 2635-13-4)

Furthermore, the coupling of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4) with β-methallyl alcohol was catalyzed by Pd(OAc)2 in combination with P(t-Bu)3.SDS of cas: 2635-13-4

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Zuo, Ziqing; Kim, Raphael S.; Watson, Donald A. published an article in 2021. The article was titled 《Synthesis of Axially Chiral 2,2′-Bisphosphobiarenes via a Nickel-Catalyzed Asymmetric Ullmann Coupling: General Access to Privileged Chiral Ligands without Optical Resolution》, and you may find the article in Journal of the American Chemical Society.SDS of cas: 2635-13-4 The information in the text is summarized as follows:

The authors report an asym. homocoupling of ortho-(iodo)arylphosphine oxides and ortho-(iodo)arylphosphonates resulting in highly enantioenriched axially chiral bisphosphine oxides and bisphosphonates. These products are readily converted to enantioenriched biaryl bisphosphines without need for chiral auxiliaries or optical resolution This provides a practical route for the development of previously unstudied atroposelective biaryl bisphosphine ligands. The conditions also proved effective for asym. dimerization of other, nonphosphorus-containing aryl halides. In addition to this study using 5-Bromobenzo[d][1,3]dioxole, there are many other studies that have used 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4SDS of cas: 2635-13-4) was used in this study.

Furthermore, the coupling of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4) with β-methallyl alcohol was catalyzed by Pd(OAc)2 in combination with P(t-Bu)3.SDS of cas: 2635-13-4

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary