Category: 2635-13-4

《Iron-catalyzed cross-coupling of Bis-(aryl)manganese nucleophiles with alkenyl halides: optimization and mechanistic investigations》 was published in Molecules in 2020. These research results belong to Rousseau, Lidie; Desaintjean, Alexandre; Knochel, Paul; Lefevre, Guillaume. Safety of 5-Bromobenzo[d][1,3]dioxole The article mentions the following:

Various substituted bis-(aryl)manganese species I (R = 4-MeOC6H4, 4-OCF3, 3,4-dioxole, etc.) were prepared from aryl bromides by one-pot insertion of magnesium turnings in the presence of LiCl and in situ trans-metalation with MnCl2 in THF at -5° within 2 h. These bis-(aryl)manganese reagents underwent smooth iron-catalyzed cross-couplings using 10 mol% Fe(acac)3 with various functionalized alkenyl iodides and bromides in 1 h at 25°. The aryl-alkenyl cross-coupling reaction mechanism was thoroughly investigated through paramagnetic 1H-NMR, which identified the key role of tris-coordinated ate-iron(II) species in the catalytic process.5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4Safety of 5-Bromobenzo[d][1,3]dioxole) was used in this study.

Furthermore, the coupling of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4) with β-methallyl alcohol was catalyzed by Pd(OAc)2 in combination with P(t-Bu)3.Safety of 5-Bromobenzo[d][1,3]dioxole

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Moriguchi, Kento; Sasaki, Ryosuke; Morita, Jun-ichi; Kamakura, Yoshinobu; Tanaka, Daisuke; Tanabe, Yoo published their research in ACS Omega in 2021. The article was titled 《Ipso-Type Regiocontrolled Benzannulation for the Synthesis of Uniquely Substituted α-Arylnaphthalenes: Application to the First Total Synthesis of Chaihunaphthone》.Recommanded Product: 2635-13-4 The article contains the following contents:

A distinctive method for synthesizing a variety of multisubstituted α-arylnaphthalenes utilizing novel regiocontrolled ipso-type [4+2]-benzannulation is presented. Ortho- and para-substituted 1-Ar1-1-Ar2-2,2-dichlorocyclopropylmethanols (AACM), I [R1 = H, Ar1 = Ph, 2-MeC6H4, 3-MeOC6H4, 2-ClC6H4, Ar2 = 2-MeC6H4, 2-ClC6H4, 2-MeOC6H4, 4-MeC6H4, 4-ClC6H4, 4-MeOC6H4; R1 = Me, Ar1 = Ph, 2-MeC6H4, 2-MeOC6H4, 3-MeOC6H4, Ar2 = 4-MeC6H4, 4-ClC6H4], were transformed to the corresponding ipso-type α-arylnaphthalenes II (Ar1 = Ph, 2-MeC6H4, 2-ClC6H4, 2-MeOC6H4, R2 = Me, Cl, OMe), and III (R1 = H, Me, R2 = Me, Cl, OMe, Ar1 = Ph, 2- MeC6H4, 2-ClC6H4, 2-MeOC6H4, 3-MeOC6H4, 4-MeC6H4). The reaction of ortho-AACM using TiCl4 or SnCl4 (1.0 equiv) proceeded smoothly to afford ipso-type α-arylnaphthalenes (seven examples; 49-69% yield) exclusively, without producing conventional benzannulation isomers. Para-AACM also underwent the reaction successfully to afford the desired ipso-type α-arylnaphthalenes (14 examples; 39-98% yield) without producing conventional benzannulation isomers. In contrast, meta-AACM underwent the previously reported conventional benzannulation. The present method exhibited sufficient substrate generality for application to ortho- and para-substituted AACM substrates bearing Me-, Cl-, and MeO- groups. The six key structures were unambiguously confirmed by X-ray structure analyses. A plausible reaction mechanism for the present ipso-type reaction is proposed and supported by three careful cross-over and comparable experiments To demonstrate the utility of the present reaction, the authors achieved the first total synthesis of chaihunaphthone, IV, a uniquely (highly congested) substituted and less accessible natural lignan lactone with three contiguous trimethoxy substituents (total of eight steps, overall 6.4% yield). In the experimental materials used by the author, we found 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4Recommanded Product: 2635-13-4)

Furthermore, the coupling of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4) with β-methallyl alcohol was catalyzed by Pd(OAc)2 in combination with P(t-Bu)3.Recommanded Product: 2635-13-4

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Recommanded Product: 5-Bromobenzo[d][1,3]dioxoleIn 2020 ,《Palladium-catalyzed intermolecular transthioetherification of aryl halides with thioethers and thioesters》 was published in Chemical Science. The article was written by Li, Yahui; Bao, Gao; Wu, Xiao-Feng. The article contains the following contents:

A new palladium-catalyzed intermol. transthioetherification reaction of aryl halides with thioethers and thioesters was developed. The synthetic utility and practicality of this catalytic protocol were demonstrated in a wide range of successful transformations (>70 examples). This catalytic protocol was applicable in carbonylative coupling processes as well, and the first example of carbonylative methylthioesterification of aryl halides was achieved. Notably, this work also provided an approach to using natural products, such as methionine and selenomethionine, as the functional group sources. The experimental part of the paper was very detailed, including the reaction process of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4Recommanded Product: 5-Bromobenzo[d][1,3]dioxole)

Furthermore, the coupling of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4) with β-methallyl alcohol was catalyzed by Pd(OAc)2 in combination with P(t-Bu)3.Recommanded Product: 5-Bromobenzo[d][1,3]dioxole

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Stereospecific Iron-Catalyzed Carbon (sp2)-Carbon (sp2) Cross-Coupling of Aryllithium with Vinyl Halides》 was written by Chen, Peng; Wang, Zhi-Yong; Peng, Xiao-Shui; Wong, Henry N. C.. Product Details of 2635-13-4This research focused onvinyl halide aryllithium prepare iron catalyst diastereoselective cross coupling; styrene preparation. The article conveys some information:

An efficient synthetic protocol involving iron-catalyzed cross-coupling of organolithium compounds with vinyl halides as key coupling partners. More than 30 examples were obtained with moderate to good yields and high stereoselectivities. The practicality of this method was evidenced by a gram-scale synthesis. In addition, a preliminary mechanistic investigation were also performed. In the experimental materials used by the author, we found 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4Product Details of 2635-13-4)

Furthermore, the coupling of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4) with β-methallyl alcohol was catalyzed by Pd(OAc)2 in combination with P(t-Bu)3.Product Details of 2635-13-4

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《An Efficient Palladium-Catalyzed α-Arylation of Acetone Below its Boiling Point》 was published in Synlett in 2020. These research results belong to Richardson, Jeffery; Mutton, Simon P.; Martin, Fionna M.; Walton, Lesley; Ledgard, Andrew J.. Name: 5-Bromobenzo[d][1,3]dioxole The article mentions the following:

The monoarylation of acetone is a powerful transformation, but is typically performed at temperatures significantly in excess of its b.p. Conditions described for performing the reaction at ambient temperatures led to significant dehalogenation when applied to a complex aryl halide. The attempts to overcome both issues in the context of our drug-discovery program was described. In the experimental materials used by the author, we found 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4Name: 5-Bromobenzo[d][1,3]dioxole)

Furthermore, the coupling of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4) with β-methallyl alcohol was catalyzed by Pd(OAc)2 in combination with P(t-Bu)3.Name: 5-Bromobenzo[d][1,3]dioxole

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Li, Xiaolan; Sun, Kai; Shen, Wenjuan; Zhang, Yong; Lu, Ming-Zhu; Luo, Xuzhong; Luo, Haiqing published their research in Organic Letters in 2021. The article was titled 《Rhodium(III)-Catalyzed Direct C-H Arylation of Various Acyclic Enamides with Arylsilanes》.HPLC of Formula: 2635-13-4 The article contains the following contents:

The stereoselective β-C(sp2)-H arylation of various acyclic enamides with arylsilanes via Rh(III)-catalyzed cross-coupling reaction was illustrated. The methodol. was characterized by extraordinary efficacy and stereoselectivity, a wide scope of substrates, good functional group tolerance, and the adoption of environmentally friendly arylsilanes. The utility of this present method was evidenced by the gram-scale synthesis and further elaboration of the product. In addition, Rh(III)-catalyzed C-H activation is considered to be the critical step in the reaction mechanism. The experimental process involved the reaction of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4HPLC of Formula: 2635-13-4)

Furthermore, the coupling of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4) with β-methallyl alcohol was catalyzed by Pd(OAc)2 in combination with P(t-Bu)3.HPLC of Formula: 2635-13-4

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Effect of Aryl Ligand Identity on Catalytic Performance of Trineopentylphosphine Arylpalladium Complexes in N-Arylation Reactions》 was written by Hu, Huaiyuan; Burlas, Corrie E.; Curley, Sabrina J.; Gruchala, Tomasz; Qu, Fengrui; Shaughnessy, Kevin H.. Computed Properties of C7H5BrO2 And the article was included in Organometallics in 2020. The article conveys some information:

Air-stable [(Np3P)Pd(Ar)Br]2 (Np = neopentyl) and (Np3P)Pd(Ar)(amine)Br complexes (amine = morpholine and isobutylamine) were prepared and tested as precatalysts for the coupling of sterically demanding aryl bromides and aniline derivatives The complexes are more active than the catalyst generated in situ from Pd2(dba)3 and PNp3. Increasing steric demand of the aryl group on Pd correlates with increased catalyst activity. Reactions catalyzed by [(Np3P)Pd(2,6-Me2C6H3)Br]2 occur efficiently at lower temperatures and with similar or higher yields than those using Pd2(dba)3/PNp3. The amine adducts give lower reaction rates and conversion to product than the [(Np3P)Pd(Ar)Br]2 complexes. The lower activity of the amine adducts appears to result from slow base-promoted reductive elimination to generate the catalytically active LPd(0) species. The results came from multiple reactions, including the reaction of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4Computed Properties of C7H5BrO2)

Furthermore, the coupling of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4) with β-methallyl alcohol was catalyzed by Pd(OAc)2 in combination with P(t-Bu)3.Computed Properties of C7H5BrO2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Ru-catalyzed isomerization of ω-alkenylboronates towards stereoselective synthesis of vinylboronates with subsequent in situ functionalization》 was published in Chemical Science in 2020. These research results belong to Ho, Guo-Ming; Segura, Lucas; Marek, Ilan. Electric Literature of C7H5BrO2 The article mentions the following:

The stereoselective preparation of synthetically versatile vinylboronates from ω-alkenylboronates was achieved through a ruthenium-catalyzed isomerization reaction. A variety of di- and trisubstituted vinylboronates were conveniently produced and could be used as a new starting point for subsequent in situ remote functionalization through either a sequential Ru/Pd or Ru/Cu double catalytic system. In the experimental materials used by the author, we found 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4Electric Literature of C7H5BrO2)

Furthermore, the coupling of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4) with β-methallyl alcohol was catalyzed by Pd(OAc)2 in combination with P(t-Bu)3.Electric Literature of C7H5BrO2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Generation of organozinc reagents from arylsulfonium salts using a nickel catalyst and zinc dust》 was published in Organic Letters in 2020. These research results belong to Yamada, Kodai; Yanagi, Tomoyuki; Yorimitsu, Hideki. Product Details of 2635-13-4 The article mentions the following:

Readily available aryldimethylsulfonium triflates react with zinc powder under nickel catalysis via the selective cleavage of the sp2-hybridized carbon-sulfur bond to produce salt-free arylzinc triflates under mild conditions. This zincation displays superb chemoselectivity and thus represents a protocol that is complementary or orthogonal to existing methods. The generated arylzinc reagents show both high reactivity and chemoselectivity in palladium-catalyzed and copper-mediated cross-coupling reactions.5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4Product Details of 2635-13-4) was used in this study.

Furthermore, the coupling of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4) with β-methallyl alcohol was catalyzed by Pd(OAc)2 in combination with P(t-Bu)3.Product Details of 2635-13-4

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Stereoselective synthesis of pentasubstituted 1,3-dienes via Ni-catalyzed reductive coupling of unsymmetrical internal alkynes》 was published in Chemical Science in 2020. These research results belong to Zhou, Zhijun; Chen, Jiachang; Chen, Herong; Kong, Wangqing. Application In Synthesis of 5-Bromobenzo[d][1,3]dioxole The article mentions the following:

The nickel-catalyzed reductive coupling of two unsym. internal alkynes overcomed the above-mentioned limitations by using a hemilabile directing group strategy to control the regioselectivity was reported. A series of synthetically challenging penta-substituted 1,3-dienes were obtained in good yields with high regio- and enantioselectivity (mostly > 20/1 rr, >90% ee). In the experimental materials used by the author, we found 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4Application In Synthesis of 5-Bromobenzo[d][1,3]dioxole)

Furthermore, the coupling of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4) with β-methallyl alcohol was catalyzed by Pd(OAc)2 in combination with P(t-Bu)3.Application In Synthesis of 5-Bromobenzo[d][1,3]dioxole

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary