Category: 2623-87-2

《Remote control of mechanical forces via mitochondrial-targeted magnetic nanospinners for efficient cancer treatment》 was written by Chen, Mengwei; Wu, Jiaojiao; Ning, Peng; Wang, Jingjing; Ma, Zuan; Huang, Liqun; Plaza, Gustavo R.; Shen, Yajing; Xu, Chang; Han, Yu; Lesniak, Maciej S.; Liu, Zhongmin; Cheng, Yu. Related Products of 2623-87-2 And the article was included in Small in 2020. The article conveys some information:

In cells, mech. forces play a key role in impacting cell behaviors, including adhesion, differentiation, migration, and death. Herein, a 20 nm mitochondria-targeted zinc-doped iron oxide nanocube is designed as a nanospinner to exert mech. forces under a rotating magnetic field (RMF) at 15 Hz and 40 mT to fight against cancer. The nanospinners can efficiently target the mitochondria of cancer cells. By means of the RMF, the nanocubes assemble in alignment with the external field and produce a localized mech. force to impair the cancer cells. Both in vitro and in vivo studies show that the nanospinners can damage the cancer cells and reduce the brain tumor growth rate after the application of the RMF. This nanoplatform provides an effective magnetomech. approach to treat deep-seated tumors in a spatiotemporal fashion. The experimental process involved the reaction of 4-Bromobutanoic acid(cas: 2623-87-2Related Products of 2623-87-2)

4-Bromobutanoic acid(cas: 2623-87-2) belongs to carboxylic acids. The chief chemical characteristic of the carboxylic acids is their acidity. They are generally more acidic than other organic compounds containing hydroxyl groups but are generally weaker than the familiar mineral acids (e.g., hydrochloric acid, HCl, sulfuric acid, H2SO4, etc.).Related Products of 2623-87-2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《New zwitterionic polyurethanes containing pendant carboxyl-pyridinium with shape memory, shape reconfiguration, and self-healing properties》 was written by Xiao, Xuan; Chen, Heng; Chen, Shaojun. Computed Properties of C4H7BrO2This research focused onzwitterionic polyurethane shape memory self healing property. The article conveys some information:

In this paper, novel zwitterionic polyurethane containing pendant carboxyl-pyridinium were successfully prepared with N,N-bis(2-hydroxyethyl) isonicotinamide (BINA) and hexamethylene diisocyanate (HDI), followed by zwitterionization with 4-bromobutyric acid. The structure, morphol. and properties, including shape memory, shape reconfiguration and self-healing properties, were carefully investigated. The obtained results showed that introduction of zwitterionic units reduced glass transition temperature The shape recovery increased with increasing carboxyl zwitterion content. Finally, good shape memory properties with 99% shape memory and 99% shape recovery was achieved. Addnl., the carboxyl-pyridinium zwitterionic polyurethane had good shape reconfiguration properties, and new permanent shapes could be reconfigured easily upon heating. Moreover, the carboxyl-pyridinium zwitterionic polyurethanes possessed moisture-induced self-healing properties, where its complex structure was self-repaired in a humidity-rich environment after inevitable damage. This study opens a new door to intelligent zwitterionic polymers, which is highly significance in the field of smart biomedical. In the experiment, the researchers used 4-Bromobutanoic acid(cas: 2623-87-2Computed Properties of C4H7BrO2)

4-Bromobutanoic acid(cas: 2623-87-2) belongs to carboxylic acids. The chief chemical characteristic of the carboxylic acids is their acidity. They are generally more acidic than other organic compounds containing hydroxyl groups but are generally weaker than the familiar mineral acids (e.g., hydrochloric acid, HCl, sulfuric acid, H2SO4, etc.).Computed Properties of C4H7BrO2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Computed Properties of C4H7BrO2In 2019 ,《A new quinoline-derived highly-sensitive fluorescent probe for the detection of hydrazine with excellent large-emission-shift ratiometric response》 appeared in Talanta. The author of the article were Wu, Qingqing; Zheng, Jianlu; Zhang, Wencui; Wang, Jianbo; Liang, Wenlang; Stadler, Florian J.. The article conveys some information:

Hydrazine is an important industrial material yet highly toxic and extremely harmful to people’s health when over-exposed in the environment, thus monitoring hydrazine is of great significance. A novel highly fluorescent fluorophore BQ-OH, based on hydroxyl- and benzo[d]oxazole-substituted quinoline structure, was synthesized and esterified with 4-bromobutyric acid to afford a fluorescent probe BQABr for the selective detection of hydrazine. The probe follows SN2(nucleophilic substitution)-cyclization sensing mechanism with remarkable response, excellent sensitivity and selectivity. Spectra experiments in aqueous solutions demonstrated that BQABr exhibited an excellent ratiometric fluorescence response toward hydrazine with 2 well separated emission bands before/after sensing reaction. Emission peak shifted over 130 nm from 387 nm to 521 nm, and unexpectedly outstanding ratio signal enhancement over 3000-fold was achieved. Due to the large spectra response, a very low detection limit of 5.8 nM (0.19 ppb) was obtained. Selectivity experiment was performed, showing BQABr had nearly no spectra response to other possible disturbing analytes. The probe-coated test papers were fabricated and successfully applied to detect gaseous hydrazine. Also, potential application for the detection of hydrazine in both environmental samples and biol. samples (living cells) was demonstrated.4-Bromobutanoic acid(cas: 2623-87-2Computed Properties of C4H7BrO2) was used in this study.

4-Bromobutanoic acid(cas: 2623-87-2) belongs to carboxylic acids. The chief chemical characteristic of the carboxylic acids is their acidity. They are generally more acidic than other organic compounds containing hydroxyl groups but are generally weaker than the familiar mineral acids (e.g., hydrochloric acid, HCl, sulfuric acid, H2SO4, etc.).Computed Properties of C4H7BrO2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Degradable PE-Based Copolymer with Controlled Ester Structure Incorporation by Cobalt-Mediated Radical Copolymerization under Mild Condition》 was published in iScience in 2020. These research results belong to Zeng, Tianyou; You, Wei; Chen, Guang; Nie, Xuan; Zhang, Ze; Xia, Lei; Hong, Chunyan; Chen, Changle; You, Yezi. Related Products of 2623-87-2 The article mentions the following:

Polyethylene (PE) is one of the most widely used materials in the world, but it is virtually undegradable and quickly accumulates in nature, which may contaminate the environment. We utilized the cobalt-mediated radical copolymerization (CMRP) of ethylene and cyclic ketene acetals (CKAs) to effectively incorporate ester groups into PE backbone as cleavable structures to make PE-based copolymer degradable under mild conditions. The content of ethylene and ester units in the produced copolymer could be finely regulated by CKA concentration or ethylene pressure. Also, the copolymerization of ethylene and CKA with other functional vinyl monomers can produce functional and degradable PE-based copolymer. All the formed PE-based copolymers could degrade in the presence of trimethylamine (Et3N). In the part of experimental materials, we found many familiar compounds, such as 4-Bromobutanoic acid(cas: 2623-87-2Related Products of 2623-87-2)

4-Bromobutanoic acid(cas: 2623-87-2) belongs to carboxylic acids. The chief chemical characteristic of the carboxylic acids is their acidity. They are generally more acidic than other organic compounds containing hydroxyl groups but are generally weaker than the familiar mineral acids (e.g., hydrochloric acid, HCl, sulfuric acid, H2SO4, etc.).Related Products of 2623-87-2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2019,ACS Catalysis included an article by Zhu, Kai; Xu, Kai; Fang, Qi; Wang, Yi; Tang, Bencan; Zhang, Fengzhi. SDS of cas: 2623-87-2. The article was titled 《Enantioselective Synthesis of Axially Chiral Biaryls via Cu-Catalyzed Acyloxylation of Cyclic Diaryliodonium Salts》. The information in the text is summarized as follows:

We report here a Cu-catalyzed enantioselective acyloxylation of cyclic diaryliodonium salts. With readily available cyclic diaryliodonium salts and ubiquitous aliphatic or (hetero)aromatic carboxylic acids as the starting materials, various axially chiral acyloxylated 2-iodobiaryls were prepared in excellent yield and with excellent enantioselectivity (mostly 99% yield and 99% ee). D. functional theory calculations were conducted to reveal the stereo- and regioselectivities. This simple reaction protocol can be employed for the late-stage modification of some drug mols. Finally, by diversity-oriented transformations, these acyloxylated 2-iodobiaryl products can be easily transformed into diverse valuable functionalized biaryls that could be used as chiral ligands or functional materials.4-Bromobutanoic acid(cas: 2623-87-2SDS of cas: 2623-87-2) was used in this study.

4-Bromobutanoic acid(cas: 2623-87-2) belongs to carboxylic acids. The chief chemical characteristic of the carboxylic acids is their acidity. They are generally more acidic than other organic compounds containing hydroxyl groups but are generally weaker than the familiar mineral acids (e.g., hydrochloric acid, HCl, sulfuric acid, H2SO4, etc.).SDS of cas: 2623-87-2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Louwsma, Jeroen; Carvalho, Alain; Lutz, Jean-Francois; Joly, Stephane; Chan-Seng, Delphine published an article in 2021. The article was titled 《Adsorption of phenylalanine-rich sequence-defined oligomers onto Kevlar fibers for fiber-reinforced polyolefin composite materials》, and you may find the article in Polymer.Recommanded Product: 4-Bromobutanoic acid The information in the text is summarized as follows:

Oligomers comprising four or sixteen phenylalanine residues with regularly intercalated aliphatic chains of different lengths prepared by solid-phase synthesis exhibit sufficient thermal stability to be used as interfacial agents and processed for the preparation of poly(propylene-co-ethylene)-based composite materials. The investigation of their adsorption on Kevlar fibers by SEM is difficult due to the surface heterogeneity of the bare Kevlar fibers. However, oligomers with four successive phenylalanine residues have been clearly observed suggesting their better adsorption on the fiber. The quantification of those oligomers adsorbed on the fibers performed gravimetrically on pellets of fibers has however revealed no significant impact of the length of the aliphatic chain.4-Bromobutanoic acid(cas: 2623-87-2Recommanded Product: 4-Bromobutanoic acid) was used in this study.

4-Bromobutanoic acid(cas: 2623-87-2) belongs to carboxylic acids. The chief chemical characteristic of the carboxylic acids is their acidity. They are generally more acidic than other organic compounds containing hydroxyl groups but are generally weaker than the familiar mineral acids (e.g., hydrochloric acid, HCl, sulfuric acid, H2SO4, etc.).Recommanded Product: 4-Bromobutanoic acid

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Yang, Dong; Chen, Jiaming; Huang, Yanping; Pan, Huiquan; Shi, Jingqi; Zhang, Yingyue; Wang, Fang; Li, Ziyuan published their research in ACS Catalysis in 2021. The article was titled 《Room-temperature Formal Aza-Wacker Cyclization through Synergistic Copper/TEMPO-catalyzed Radical Relay》.Recommanded Product: 2623-87-2 The article contains the following contents:

A formal aza-Wacker cyclization of alkenylated carbamates or amides through a synergistic Cu/TEMPO-catalyzed radical relay pathway using N-fluorobenzenesulfonimide (NFSI) as an external oxidant afforded oxazolidinones, pyrrolidones I [R= Cl, Br, F, R1 = Me, Et, n-Pr; R2 = H, Me, Et; R1R2 = cyclohex-1-en-1-yl; X = CH2, O] and isoindolinones II [R3 = Ph, 4-MeOC6H4, OBn, etc.] under mild conditions. In this efficient cyclization of alkenylated carbamates or amides at room temperature, the imidyl nitrogen-centered radical (NCR) generated by NFSI induced carbamate or amido NCR from the substrate via N-H homolysis to realize the radical relay process, which was supported by results of control experiments In the experiment, the researchers used 4-Bromobutanoic acid(cas: 2623-87-2Recommanded Product: 2623-87-2)

4-Bromobutanoic acid(cas: 2623-87-2) belongs to carboxylic acids. The chief chemical characteristic of the carboxylic acids is their acidity. They are generally more acidic than other organic compounds containing hydroxyl groups but are generally weaker than the familiar mineral acids (e.g., hydrochloric acid, HCl, sulfuric acid, H2SO4, etc.).Recommanded Product: 2623-87-2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

The author of 《Fine-Tuning the Linear Release Rate of Paclitaxel-Bearing Supramolecular Filament Hydrogels through Molecular Engineering》 were Chakroun, Rami W.; Wang, Feihu; Lin, Ran; Wang, Yin; Su, Hao; Pompa, Danielle; Cui, Honggang. And the article was published in ACS Nano in 2019. Related Products of 2623-87-2 The author mentioned the following in the article:

One key design feature in the development of any local drug delivery system is the controlled release of therapeutic agents over a certain period of time. In this context, we report the characteristic feature of a supramol. filament hydrogel system that enables a linear and sustainable drug release over the period of several months. Through covalent linkage with a short peptide sequence, we are able to convert an anticancer drug, paclitaxel (PTX), to a class of prodrug hydrogelators with varying critical gelation concentrations These self-assembling PTX prodrugs associate into filamentous nanostructures in aqueous conditions and consequently percolate into a supramol. filament network in the presence of appropriate counterions. The intriguing linear drug release profile is rooted in the supramol. nature of the self-assembling filaments which maintain a constant monomer concentration at the gelation conditions. We found that mol. engineering of the prodrug design, such as varying the number of oppositely charged amino acids or through the incorporation of hydrophobic segments, allows for the fine-tuning of the PTX linear release rate. In cell studies, these PTX prodrugs can exert effective cytotoxicity against glioblastoma cell lines and also primary brain cancer cells derived from patients and show enhanced tumor penetration in a cancer spheroid model. We believe this drug-bearing hydrogel platform offers an exciting opportunity for the local treatment of human diseases. The results came from multiple reactions, including the reaction of 4-Bromobutanoic acid(cas: 2623-87-2Related Products of 2623-87-2)

4-Bromobutanoic acid(cas: 2623-87-2) belongs to carboxylic acids. The chief chemical characteristic of the carboxylic acids is their acidity. They are generally more acidic than other organic compounds containing hydroxyl groups but are generally weaker than the familiar mineral acids (e.g., hydrochloric acid, HCl, sulfuric acid, H2SO4, etc.).Related Products of 2623-87-2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

The author of 《Iminyl Radicals by Reductive Cleavage of N-O Bond in Oxime Ether Promoted by SmI2: A Straightforward Synthesis of Five-Membered Cyclic Imines》 were Huang, Fei; Zhang, Songlin. And the article was published in Organic Letters in 2019. Related Products of 2623-87-2 The author mentioned the following in the article:

A new generation method of N-centered radicals from the reductive cleavage of the N-O bond in oxime ether promoted by SmI2 is reported for the first time. The in-situ-generated N-centered radicals underwent intramol. cyclization to afford five-membered cyclic imines in two manners: N-centered radical addition and N-centered anion nucleophilic substitution. From a synthetic point of view, an efficient synthetic method of five-membered cyclic imines was developed. A mechanism of the transformation was proposed. In the experiment, the researchers used many compounds, for example, 4-Bromobutanoic acid(cas: 2623-87-2Related Products of 2623-87-2)

4-Bromobutanoic acid(cas: 2623-87-2) belongs to carboxylic acids. The chief chemical characteristic of the carboxylic acids is their acidity. They are generally more acidic than other organic compounds containing hydroxyl groups but are generally weaker than the familiar mineral acids (e.g., hydrochloric acid, HCl, sulfuric acid, H2SO4, etc.).Related Products of 2623-87-2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《A “”turn-on”” fluorescent probe based on V-shaped bis-coumarin for detection of hydrazine》 was written by Jiang, Xingzong; Shangguan, Mingqin; Lu, Zhen; Yi, Sili; Zeng, Xiaoyang; Zhang, Yongle; Hou, Linxi. Electric Literature of C4H7BrO2 And the article was included in Tetrahedron in 2020. The article conveys some information:

Hydrazine (N2H4) has been classified as an environmental contaminant and human carcinogen owing to its high toxicity. Exposed to high concentration of hydrazine can cause irreversible damage to human bodies. Hence, it is significant to explore an effective anal. method to selectively recognize and detect it. In this work, an intramol. charge transfer (ICT) based probe 1 (I) was designed and synthesized by condensation of V-shaped bis-coumarin and 4-bromobutyric acid. The V-shaped bis-coumarin with π-expanded system endowed the probe 1 larger stokes shift and superior tolerance to photobleaching. This “”turn-on”” probe exhibited a high selectivity towards hydrazine over other common ions and amine-containing species with a distinct fluorescent enhancement at 555 nm. It could rapidly detect hydrazine over a wide pH range and the detection limit was as low as 4.2 ppb. The large shift of absorption spectrum enabled it to detect hydrazine in real water samples and gas-state hydrazine by “”naked-eyes””. In the experiment, the researchers used many compounds, for example, 4-Bromobutanoic acid(cas: 2623-87-2Electric Literature of C4H7BrO2)

4-Bromobutanoic acid(cas: 2623-87-2) belongs to carboxylic acids. The chief chemical characteristic of the carboxylic acids is their acidity. They are generally more acidic than other organic compounds containing hydroxyl groups but are generally weaker than the familiar mineral acids (e.g., hydrochloric acid, HCl, sulfuric acid, H2SO4, etc.).Electric Literature of C4H7BrO2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary